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4,6-Dichloro-2-(trifluoromethyl)-5-pyrimidinamine | CAS:2344-17-4
4,6-Dichloro-2-(trifluoromethyl)-5-pyrimidinamine
  • Name:4,6-Dichloro-2-(trifluoromethyl)-5-pyrimidinamine
  • CAS:2344-17-4
  • Synonyms:NSC 56143
  • Molecular Formula:C5H2Cl2F3N3
  • Molecular Weight:231.99
  • EINESC:

Description

Properties

Boiling point 202 ºC
Flash point 76 ºC
Density 1.711

Safety

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SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.Cüneyt Cirak et al.Natural product communications, 5(6), 897-898 (2010-07-10) 1H NMR determination of hypericin and pseudohypericin in complex natural mixtures by the use of strongly deshielded OH groups.Evangelos C Tatsis et al.Analytica chimica acta, 607(2), 219-226 (2008-01-15) LC-MS and LC-PDA analysis of Hypericum empetrifolium and Hypericum sinaicum.Feras Q Alali et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 64(7-8), 476-482 (2009-10-02) The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?Hilde Laggner et al.Free radical research, 41(2), 234-241 (2007-03-17) Effects of UV-B on secondary metabolites of St. John's Wort (Hypericum perforatum L.) grown in controlled environments.Melissa L Brechner et al.Photochemistry and photobiology, 87(3), 680-684 (2011-02-01) Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss. subsp. apollinis (Boiss. & Heldr.) Robson & Strid methanol extract.E M Galati et al.Phytotherapy research : PTR, 22(6), 766-771 (2008-05-01) Determination of enantiomerization barriers of hypericin and pseudohypericin by dynamic high-performance liquid chromatography on immobilized polysaccharide-type chiral stationary phases and off-column racemization experiments.Alessia Ciogli et al.Chirality, 22(5), 463-471 (2009-08-01) Flavonoid glycosides and naphthodianthrones in the sawfly Tenthredo zonula and its host-plants, Hypericum perforatum and H. hirsutum.Sara L Crockett et al.Journal of chemical ecology, 37(9), 943-952 (2011-08-05) Hypericum perforatum: a 'modern' herbal antidepressant: pharmacokinetics of active ingredients.Mario Wurglics et al.Clinical pharmacokinetics, 45(5), 449-468 (2006-04-28) Elicitation of secondary metabolism in Hypericum perforatum by rhizosphere bacteria and derived elicitors in seedlings and shoot cultures.F Javier Gutiérrez Mañero et al.Pharmaceutical biology, 50(10), 1201-1209 (2012-08-21) In vitro photochemical and phototoxicological characterization of major constituents in St. John's Wort (Hypericum perforatum) extracts.Satomi Onoue et al.Phytochemistry, 72(14-15), 1814-1820 (2011-07-26) Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.Emilio Russo et al.Phytotherapy research : PTR, 28(5), 643-655 (2013-07-31) Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L.Silvio Sosa et al.The Journal of pharmacy and pharmacology, 59(5), 703-709 (2007-05-26) Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum.Souvik Kusari et al.Phytochemistry, 70(10), 1222-1232 (2009-08-18) Investigating the effectiveness of St John's wort herb as an antimicrobial agent against mycobacteria.Trent Mortensen et al.Phytotherapy research : PTR, 26(9), 1327-1333 (2012-02-02) Inhibition of 17β-estradiol activation by CYP1A1: genotype- and regioselective inhibition by St. John's Wort and several natural polyphenols.Dieter Schwarz et al.Biochimica et biophysica acta, 1814(1), 168-174 (2010-10-05) Pseudohypericin and hyperforin in Hypericum perforatum from Northern Turkey: variation among populations, plant parts and phenological stages.Cüneyt Cirak et al.Journal of integrative plant biology, 50(5), 575-580 (2008-08-21) Inhibition of prostaglandin E(2) production by anti-inflammatory hypericum perforatum extracts and constituents in RAW264.7 Mouse Macrophage Cells.Kimberly D P Hammer et al.Journal of agricultural and food chemistry, 55(18), 7323-7331 (2007-08-19) Hypericin and pseudohypericin concentrations of a valuable medicinal plant Hypericum perforatum L. are enhanced by arbuscular mycorrhizal fungi.Szymon Zubek et al.Mycorrhiza, 22(2), 149-156 (2011-06-01) [The influence of some elicitors on growth and morphogenesis of Hypericum perforatum callus cultures].G R Vardapetian et al.Ontogenez, 37(6), 419-423 (2006-12-16) Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction.Kimberly D P Hammer et al.Phytochemistry, 69(12), 2354-2362 (2008-08-19) Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species.Cüneyt Cirak et al.Natural product research, 23(13), 1189-1195 (2009-09-05) The inhibition of lipopolysaccharide-induced macrophage inflammation by 4 compounds in Hypericum perforatum extract is partially dependent on the activation of SOCS3.Nan Huang et al.Phytochemistry, 76, 106-116 (2012-01-17) Rapid and efficient purification of naphthodianthrones from St. John's wort extract by using liquid-liquid extraction and SEC.Anastasia Karioti et al.Journal of separation science, 32(9), 1374-1382 (2009-04-11) Identification of anti-inflammatory constituents in Hypericum perforatum and Hypericum gentianoides extracts using RAW 264.7 mouse macrophages.Nan Huang et al.Phytochemistry, 72(16), 2015-2023 (2011-08-23) Variation of hypericins in Hypericum triquetrifolium Turra growing in different locations of Turkey during plant growth.Ali Kemal Ayan et al.Natural product research, 22(18), 1597-1604 (2008-12-17)
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