Density	1.294±0.06 g/cm3 (20 º

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Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine.Marisol Chang et al.PloS one, 7(6), e40087-e40087 (2012-07-07) Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine.Li-Hui Sun et al.Journal of microbiology and biotechnology, 22(6), 826-831 (2012-05-11) Hypoglycemic properties of some preparations and compounds from Artemisia ludoviciana Nutt.Gerardo D Anaya-Eugenio et al.Journal of ethnopharmacology, 155(1), 416-425 (2014-06-04) Novel GAA mutations in patients with Pompe disease.Lauro Thiago Turaça et al.Gene, 561(1), 124-131 (2015-02-15) [The Study TO Prevent Non-Insulin Dependent Diabetes Mellitus trial (acarbose)].Rimei Nishimura Nihon rinsho. Japanese journal of clinical medicine, 63 Suppl 2, 478-482 (2005-03-23) Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases.David R da Rocha et al.Carbohydrate research, 350, 14-19 (2012-01-25) Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of Morinda lucida and Momordica charantia Leaves from Benin.Michaelle Chokki et al.Foods (Basel, Switzerland), 9(4) (2020-04-09) Human blood vessel organoids as a model of diabetic vasculopathy.Reiner A Wimmer et al.Nature, 565(7740), 505-510 (2019-01-18) Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and sulfonylureas: meta-analysis of placebo-controlled trials.Matteo Monami et al.Advances in therapy, 29(9), 736-746 (2012-08-28) Halogenated metabolites isolated from Penicillium citreonigrum.Wei-Hua Yuan et al.Chemistry & biodiversity, 11(7), 1078-1087 (2014-07-22) Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus.Sophie Delorme et al.Current opinion in pharmacology, 5(2), 184-189 (2005-03-23) Early improvement in carotid plaque echogenicity by acarbose in patients with acute coronary syndromes.Mitsumasa Hirano et al.Circulation journal : official journal of the Japanese Circulation Society, 76(6), 1452-1460 (2012-03-29) Lactobacillus strains isolated from infant faeces possess potent inhibitory activity against intestinal alpha- and beta-glucosidases suggesting anti-diabetic potential.Harsh Panwar et al.European journal of nutrition, 53(7), 1465-1474 (2014-01-15) Role of intestinal peptides and the autonomic nervous system in postprandial hypotension in patients with multiple system atrophy.Takeshi Fukushima et al.Journal of neurology, 260(2), 475-483 (2012-09-18) Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.Malose J Mphahlele et al.Bioorganic chemistry, 97, 103702-103702 (2020-03-09) Cardiovascular benefits of acarbose in impaired glucose tolerance and type 2 diabetes.Uwe Zeymer International journal of cardiology, 107(1), 11-20 (2005-12-13) Four flavonoid compounds from Phyllostachys edulis leaf extract retard the digestion of starch and its working mechanisms.Jun-Peng Yang et al.Journal of agricultural and food chemistry, 62(31), 7760-7770 (2014-07-16) Clinical utility of acarbose, an alpha-glucosidase inhibitor in cardiometabolic disorders.Sho-ichi Yamagishi et al.Current drug metabolism, 10(2), 159-163 (2009-03-12) Modified Regulatory Pathways to Approve Generic Drugs in the US and a Systematic Review of Their Outcomes.Aaron S Kesselheim et al.Drugs, 75(6), 633-650 (2015-03-31) Nimbandiolactone-21 and nimbandioloxyfuran, two new 28-norlimonoids from the leaves of Azadirachta indica (Meliaceae).Nhi Y Thi Nguyen et al.Journal of Asian natural products research, 21(9), 867-872 (2018-07-11) Effect of Moringa oleifera Leaf Powder on Postprandial Blood Glucose Response: In Vivo Study on Saharawi People Living in Refugee Camps.Alessandro Leone et al.Nutrients, 10(10) (2018-10-17) Efficacy and safety profile evaluation of acarbose alone and in association with other antidiabetic drugs: a systematic review.Giuseppe Derosa et al.Clinical therapeutics, 34(6), 1221-1236 (2012-05-09) Review of acarbose therapeutic strategies in the long-term treatment and in the prevention of type 2 diabetes.H W M Breuer International journal of clinical pharmacology and therapeutics, 41(10), 421-440 (2004-01-06) Effect of acarbose on vascular disease in patients with abnormal glucose tolerance.Markolf Hanefeld et al.Cardiovascular drugs and therapy, 22(3), 225-231 (2008-03-01) Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial.Rury R Holman et al.American heart journal, 168(1), 23-29 (2014-06-24) Antitumor effects and immune regulation activities of a purified polysaccharide extracted from Juglan regia.Wang Ruijun et al.International journal of biological macromolecules, 72, 771-775 (2014-09-30) Inhibitory activity of minor phlorotannins from Ecklonia cava on α-glucosidase.Sae Rom Park et al.Food chemistry, 257, 128-134 (2018-04-07) Comparative antioxidant and antidiabetic effects of Syzygium polyanthumleaf and Momordica charantia fruit extracts.Muhammad Jihad Sandikapura et al.Pakistan journal of pharmaceutical sciences, 31(2(Suppl.)), 623-635 (2018-04-08) Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes.Markolf Hanefeld Cardiovascular diabetology, 6, 20-20 (2007-08-19) Antibacterial, antioxidant and hypoglycaemic effects of Thymus capitatus (L.) Hoffmanns. et Link leaves' fractions.Liliana Iauk et al.Journal of enzyme inhibition and medicinal chemistry, 30(3), 360-365 (2014-07-18) Inhibitory potential of Turbinaria ornata against key metabolic enzymes linked to diabetes.P S Unnikrishnan et al.BioMed research international, 2014, 783895-783895 (2014-07-23) Study of Antiglycation, Hypoglycemic, and Nephroprotective Activities of the Green Dwarf Variety Coconut Water (Cocos nucifera L.) in Alloxan-Induced Diabetic Rats.Isabella F D Pinto et al.Journal of medicinal food, 18(7), 802-809 (2015-02-05) Usefulness of acarbose and dietary modifications to limit glycemic variability following Roux-en-Y gastric bypass as assessed by continuous glucose monitoring.Patrick Ritz et al.Diabetes technology & therapeutics, 14(8), 736-740 (2012-08-03) Influence of Acarbose on Plasma Glucose Fluctuations in Insulin-Treated Patients with Type 2 Diabetes: A Pilot Study.Feng-Fei Li et al.International journal of endocrinology, 2015, 903524-903524 (2015-12-08) Effect of acarbose on postprandial blood glucose concentrations in healthy cats fed low and high carbohydrate diets.Ranee Singh et al.Journal of feline medicine and surgery, 17(10), 848-857 (2014-10-26) Vindogentianine, a hypoglycemic alkaloid from Catharanthus roseus (L.) G. Don (Apocynaceae).Soon Huat Tiong et al.Fitoterapia, 102, 182-188 (2015-02-11) An effective and simplified scale-up strategy for acarbose fermentation based on the carbon source control.Kun-tai Li et al.World journal of microbiology & biotechnology, 28(2), 749-753 (2012-07-19) Podocyte as a potential target of inflammation: role of pioglitazone hydrochloride in patients with type 2 diabetes.Yan Xing et al.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 18(4), 493-498 (2012-03-24) Mechanistic investigation of anthocyanidin derivatives as α-glucosidase inhibitors.Jang Hoon Kim et al.Bioorganic chemistry, 87, 803-809 (2019-04-13) Melanogenesis inhibitory effect of aerial part of Pueraria thunbergiana in vitro and in vivo.EunByeol Han et al.Archives of dermatological research, 307(1), 57-72 (2014-07-27) Utility of an oxidation reaction for the spectrophotometric determination of acarbose in controlled release tablets at various simulated gastrointestinal media.Vivek Ranjan Sinha et al.Acta poloniae pharmaceutica, 69(1), 23-32 (2012-05-12) Hypolipidemic and hypoglycemic effects of Centella asiatica (L.) extract in vitro and in vivo.Nattapon Supkamonseni et al.Indian journal of experimental biology, 52(10), 965-971 (2014-10-28) Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes.Qian Li et al.Food & function, 6(12), 3693-3701 (2015-10-08) Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida-A Comparative Study.Joanna Truba et al.Plants (Basel, Switzerland), 9(1) (2020-01-23) Pneumatosis coli induced by acarbose administration for diabetes mellitus. Case report and literature review.L Furio et al.Minerva gastroenterologica e dietologica, 52(3), 339-346 (2006-09-15) A column-switching HPLC-MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders.Antonina Gucciardi et al.Biomedical chromatography : BMC, 28(8), 1131-1139 (2014-01-23) [Acarbose-induced acute hepatitis. Report of two events in the same patient].J de la Vega et al.Gastroenterologia y hepatologia, 23(6), 282-284 (2004-08-25) Postprandial hyperglycaemia and vascular damage--the benefits of acarbose.Peter N Båvenholm et al.Diabetes & vascular disease research, 3(2), 72-79 (2006-10-25) Berry components inhibit α-glucosidase in vitro: synergies between acarbose and polyphenols from black currant and rowanberry.Ashley S Boath et al.Food chemistry, 135(3), 929-936 (2012-09-08) Comparative Cholinesterase, α-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives.Ashfaq Ahmad et al.Drug design, development and therapy, 14, 2165-2178 (2020-07-02) A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants.L H Gu et al.Journal of chromatography. A, 1411, 116-122 (2015-08-19) The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.Patrick Schwientek et al.BMC genomics, 13, 112-112 (2012-03-27) [Cost-effectiveness of the addition of acarbose to the treatment of patients with type-2 diabetes in Spain].Carme Piñol et al.Gaceta sanitaria, 21(2), 97-104 (2007-04-11) The anthocyanins in black currants regulate postprandial hyperglycaemia primarily by inhibiting α-glucosidase while other phenolics modulate salivary α-amylase, glucose uptake and sugar transporters.Sisir Kumar Barik et al.The Journal of nutritional biochemistry, 78, 108325-108325 (2020-01-18) Anti-diabetic activity of peony seed oil, a new resource food in STZ-induced diabetic mice.Jianhui Su et al.Food & function, 6(9), 2930-2938 (2015-08-08) Enhanced production of acarbose and concurrently reduced formation of impurity c by addition of validamine in fermentation of Actinoplanes utahensis ZJB-08196.Ya-Ping Xue et al.BioMed research international, 2013, 705418-705418 (2013-03-14) Possible effects of dietary polyphenols on sugar absorption and digestion.Gary Williamson Molecular nutrition & food research, 57(1), 48-57 (2012-11-28) Hypoglycemic, antihyperglycemic, and antioxidant effects of the edible plant Anoda cristata.Krutzkaya Juárez-Reyes et al.Journal of ethnopharmacology, 161, 36-45 (2014-12-10) Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis.Qing Liu et al.Journal of natural products, 77(7), 1594-1600 (2014-06-24) Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in Chinese patients with type 2 diabetes mellitus.Benli Su et al.Journal of diabetes, 7(5), 729-739 (2014-10-21) Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.Eberhard Standl et al.Diabetes & vascular disease research, 9(3), 163-169 (2012-04-18) Molecular basis for the recognition of long-chain substrates by plant α-glucosidases.Takayoshi Tagami et al.The Journal of biological chemistry, 288(26), 19296-19303 (2013-05-21) An optimized industrial fermentation processes for acarbose production by Actinoplanes sp. A56.Kun-tai Li et al.Bioresource technology, 118, 580-583 (2012-06-19) A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi.Dinh Tri Mai et al.Natural product research, 29(15), 1437-1441 (2015-02-13) Sucrose induces vesicle accumulation and autophagy.Takahiro Higuchi et al.Journal of cellular biochemistry, 116(4), 609-617 (2014-11-13) Hypoglycemic, antihyperglycemic, and antioxidant effects of the edible plant Anoda cristata.Krutzkaya Juárez-Reyes et al.Journal of ethnopharmacology, 161, 36-45 (2014-12-10) Possible effects of dietary polyphenols on sugar absorption and digestion.Gary Williamson Molecular nutrition & food research, 57(1), 48-57 (2012-11-28) Enhanced production of acarbose and concurrently reduced formation of impurity c by addition of validamine in fermentation of Actinoplanes utahensis ZJB-08196.Ya-Ping Xue et al.BioMed research international, 2013, 705418-705418 (2013-03-14) A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants.L H Gu et al.Journal of chromatography. A, 1411, 116-122 (2015-08-19) The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.Patrick Schwientek et al.BMC genomics, 13, 112-112 (2012-03-27) Enzyme inhibitory and radical scavenging effects of some antidiabetic plants of Turkey.Nilüfer Orhan et al.Iranian journal of basic medical sciences, 17(6), 426-432 (2014-08-21) Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.Doudou Huang et al.Journal of ethnopharmacology, 163, 256-263 (2015-01-27) [Cost-effectiveness of the addition of acarbose to the treatment of patients with type-2 diabetes in Spain].Carme Piñol et al.Gaceta sanitaria, 21(2), 97-104 (2007-04-11) Antithrombotic and antidiabetic flavonoid glycosides from the grains of Sorghum bicolor (L.) Moench var. hwanggeumchal.Phi-Hung Nguyen et al.Archives of pharmacal research, 37(11), 1394-1402 (2014-06-25) Antidiabetic property of Symplocos cochinchinensis is mediated by inhibition of alpha glucosidase and enhanced insulin sensitivity.Kalathookunnel Antony Antu et al.PloS one, 9(9), e105829-e105829 (2014-09-04) Acarbose: oral anti-diabetes drug with additional cardiovascular benefits.Markolf Hanefeld et al.Expert review of cardiovascular therapy, 6(2), 153-163 (2008-02-06) Peptide modulators of alpha-glucosidase.Irena Roskar et al.Journal of diabetes investigation, 6(6), 625-631 (2015-11-07) Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats.Ramith Ramu et al.Journal of the science of food and agriculture, 95(1), 165-173 (2014-04-23) Treatment of impaired glucose tolerance with acarbose and its effect on intima-media thickness: a substudy of the STOP-NIDDM trial (study to prevent non-insulin-dependent diabetes mellitus).Markolf Hanefeld Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 12 Suppl 1, 56-59 (2006-04-22) Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.Md Nurul Islam et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 55-62 (2014-04-10) The ethanol extract of Eucommia ulmoides Oliv. leaves inhibits disaccharidase and glucose transport in Caco-2 cells.Yanyan Zhang et al.Journal of ethnopharmacology, 163, 99-105 (2015-01-27) Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial.Jean-Louis Chiasson Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 12 Suppl 1, 25-30 (2006-04-22) Reducing the risk of type 2 diabetes: early identification of high-risk individuals and treatment with acarbose.Chang-Yu Pan Current diabetes reviews, 3(2), 141-148 (2008-01-29) A case of slowly progressive type 1 diabetes with insulin independence maintained for 10 years with α-glucosidase inhibitor monotherapy.Yuichiro Munakata et al.Internal medicine (Tokyo, Japan), 51(24), 3391-3394 (2012-12-22) Protein-protein interactions among enzymes of starch biosynthesis in high-amylose barley genotypes reveal differential roles of heteromeric enzyme complexes in the synthesis of A and B granules.Zaheer Ahmed et al.Plant science : an international journal of experimental plant biology, 233, 95-106 (2015-02-26) Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase.Mezna Saleh Altowyan et al.Molecules (Basel, Switzerland), 24(12) (2019-06-28) Inhibitory Potential of Constituents from Osmanthus fragrans and Structural Analogues Against Advanced Glycation End Products, α-Amylase, α-Glucosidase, and Oxidative Stress.Ji-Yeon Yang et al.Scientific reports, 7, 45746-45746 (2017-04-01) [Effects of acarbose, alpha-glucosidase inhibitor in treatment of impaired glucose tolerance].Noriko Sakamoto et al.Nihon rinsho. Japanese journal of clinical medicine, 63 Suppl 2, 451-456 (2005-03-23) Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases.Hanumantharayappa Bharathkumar et al.PloS one, 9(7), e102759-e102759 (2014-07-23) Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase of Escherichia coli.Simon C Weiss et al.The Journal of biological chemistry, 290(35), 21352-21364 (2015-07-04) Enzymatic synthesis of Acarviosyl-maltooligosaccharides using disproportionating enzyme 1.Takayoshi Tagami et al.Bioscience, biotechnology, and biochemistry, 77(2), 312-319 (2013-02-09) Effects of acarbose on proinsulin and insulin secretion and their potential significance for the intermediary metabolism and cardiovascular system.Christoph Rosak et al.Current diabetes reviews, 5(3), 157-164 (2009-08-20) Seven-day subcutaneous continuous glucose monitoring demonstrates that treatment with acarbose attenuates late dumping syndrome in a woman with gastrectomy for gastric cancer.Silvio Buscemi et al.Diabetes research and clinical practice, 99(1), e1-e2 (2012-11-14) A review of the economic evidence for acarbose in the prevention of diabetes and cardiovascular events in individuals with impaired glucose tolerance.R G Josse et al.International journal of clinical practice, 60(7), 847-855 (2006-07-22) Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.S Kim et al.Journal of clinical pharmacy and therapeutics, 39(4), 424-431 (2014-05-09) Screening of α-glucosidase inhibitory activity from some plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae.Berna Elya et al.Journal of biomedicine & biotechnology, 2012, 281078-281078 (2011-12-22) In vitro studies to assess the antidiabetic, antiperoxidative, and radical scavenging potential of Stereospermum colais.M Priya Rani et al.Pharmaceutical biology, 50(10), 1254-1260 (2012-08-21) Antimicrobial and enzyme inhibitory activities of the constituents of Plectranthus madagascariensis (Pers.) Benth.Renata Kubínová et al.Journal of enzyme inhibition and medicinal chemistry, 29(5), 749-752 (2014-02-11) The hypoglycemic effect of a polysaccharide (GLP) from Gracilaria lemaneiformis and its degradation products in diabetic mice.Xubiao Liao et al.Food & function, 6(8), 2542-2549 (2015-06-27) Acarbose treatment enhances mid-regional pro-atrial natriuretic peptide concentrations in non-diabetic individuals: further evidence for a common cardiometabolic pathway?N Rudovich et al.Diabetologia, 55(12), 3392-3395 (2012-09-20) Novel Flavonoid Glycosides of Quercetin from Leaves and Flowers of Gaiadendron punctatum G.Don. (Violeta de Campo), used by the Saraguro Community in Southern Ecuador, Inhibit α-Glucosidase Enzyme.Héctor Cedeño et al.Molecules (Basel, Switzerland), 24(23) (2019-11-28) Hypoglycemic and antioxidant effects of Daraesoon (Actinidia arguta shoot) in animal models of diabetes mellitus.Ah-Yeon Lee et al.Nutrition research and practice, 9(3), 262-267 (2015-06-11) The anti-obesity potential of sigmoidin A.Solomon Habtemariam Pharmaceutical biology, 50(12), 1519-1522 (2012-09-18) Inhibitory effect of a weight-loss Chinese herbal formula RCM-107 on pancreatic α-amylase activity: Enzymatic and in silico approaches.Shiqi Luo et al.PloS one, 15(4), e0231815-e0231815 (2020-04-30) Multiple cerebral infarctions related to famotidine-induced eosinophilia.Chi-Shun Wu et al.Journal of neurology, 259(10), 2229-2231 (2012-05-16) Alpha glucosidase inhibitors.Sanjay Kalra JPMA. The Journal of the Pakistan Medical Association, 64(4), 474-476 (2014-05-29)

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