Melting point	102-103 ºC
Density	1.255

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Source	SDS/MSDS Samples
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Peer-Reviewed Papers

Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium.Moon Kyoung Kim et al.Journal of pharmaceutical sciences, 94(12), 2644-2655 (2005-11-01) Effect of ethanol on hepatobiliary transport of cationic drugs. A study in the isolated perfused rat liver, rat hepatocytes and rat mitochondria.H Steen et al.Journal of hepatology, 21(3), 308-314 (1994-09-01) Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract.Won-Sik Shim et al.Archives of pharmacal research, 31(5), 671-677 (2008-05-16) Effect of a new hepatoprotective agent, YH-439, on the hepatobiliary transport of organic cations (OCs): selective inhibition of sinusoidal OCs uptake without influencing glucose uptake and canalicular OCs excretion.Soon-Sun Hong et al.Archives of pharmacal research, 28(3), 330-334 (2005-04-19) Ammonium-based cellulose solvents suitable for homogeneous etherification.Sarah Köhler et al.Macromolecular bioscience, 9(9), 836-841 (2009-07-23) Hepatobiliary excretion of tributylmethylamonium in rats with lipopolysaccharide-induced acute inflammation.In-Kyung Lee et al.Archives of pharmacal research, 25(6), 969-972 (2003-01-04) [Determination of carboxylic acid on a new capillary column prepared by ourselves].D M Kou et al.Se pu = Chinese journal of chromatography, 17(6), 550-552 (2003-01-30) Decreased biliary excretion of tributylmethyl ammonium in cholestyramine pretreated rats due to reduced formation of ion-pair complexes with hepatic bile salts.M K Choi et al.Biopharmaceutics & drug disposition, 28(9), 485-490 (2007-10-24) Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.R H Moseley et al.The Journal of pharmacology and experimental therapeutics, 276(2), 561-567 (1996-02-01) Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes.Im-Sook Song et al.Archives of pharmacal research, 25(6), 984-988 (2003-01-04) Modulators of the protein kinase C system influence biliary excretion of cationic drugs.H Steen et al.Hepatology (Baltimore, Md.), 18(5), 1208-1215 (1993-11-01) Functional impairment of sinusoidal membrane transport of organic cations in rats with CCl4-induced hepatic failure.S S Hong et al.Pharmaceutical research, 17(7), 833-838 (2000-09-16) Sequestration of organic cations by acidified hepatic endocytic vesicles and implications for biliary excretion.R W Van Dyke et al.The Journal of pharmacology and experimental therapeutics, 261(1), 1-11 (1992-04-01) Mechanism of the stationary canalicular excretion of tributylmethyl ammonium in rats with a CCl4-induced acute hepatic injury.Min-Koo Choi et al.Journal of pharmaceutical sciences, 94(2), 317-326 (2004-12-01) Differential effects of metabolic inhibitors on cellular and mitochondrial uptake of organic cations in rat liver.H Steen et al.Biochemical pharmacology, 45(4), 809-818 (1993-02-24) Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted.J W Smit et al.British journal of pharmacology, 124(2), 416-424 (1998-06-26) Heterologous expression of various P-glycoproteins in polarized epithelial cells induces directional transport of small (type 1) and bulky (type 2) cationic drugs.J W Smit et al.The Journal of pharmacology and experimental therapeutics, 286(1), 321-327 (1998-07-10) Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers.Soon-Sun Hong et al.Archives of pharmacal research, 29(4), 318-322 (2006-05-10) A multispecific uptake system for taurocholate, cardiac glycosides and cationic drugs in the liver.H Steen et al.Biochemical pharmacology, 44(12), 2323-2331 (1992-12-15) Different activity of ATP dependent transport across the canalicular membrane for tributylmethylammonium and triethylmethylammonium as a potential mechanism of the preferential biliary excretion for tributylmethylammonium in the rat.I S Song et al.Pharmaceutical research, 16(4), 540-544 (1999-05-05) Canalicular membrane transport is primarily responsible for the difference in hepatobiliary excretion of triethylmethylammonium and tributylmethylammonium in rats.Y H Han et al.Drug metabolism and disposition: the biological fate of chemicals, 27(8), 872-879 (1999-07-27) Contribution of ion pair complexation with bile salts to biliary excretion of organic cations in rats.I S Song et al.American journal of physiology. Gastrointestinal and liver physiology, 281(2), G515-G525 (2001-07-12) Altered pharmacokinetics and hepatic uptake of TBuMA in ethynylestradiol-induced cholestasis.Soon-Sun Hong et al.Archives of pharmacal research, 29(4), 323-327 (2006-05-10) Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides.J E van Montfoort et al.The Journal of pharmacology and experimental therapeutics, 298(1), 110-115 (2001-06-16) Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level.J W Smit et al.British journal of pharmacology, 123(3), 361-370 (1998-03-21)

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