Boiling point	83-85 ºC (4 mmHg)
Flash point	>110 ºC
Density	1.065
Refractive index	1.509

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

MMP Inhibition Preserves Integrin Ligation and FAK Activation to Induce Survival and Regeneration in RGCs Following Optic Nerve Damage.Philippe M D'Onofrio et al.Investigative ophthalmology & visual science, 60(2), 634-649 (2019-02-12) Black rice-derived anthocyanins inhibit HER-2-positive breast cancer epithelial-mesenchymal transition-mediated metastasis in vitro by suppressing FAK signaling.Jie Zhou et al.International journal of molecular medicine, 40(6), 1649-1656 (2017-10-19) Mechanical Force Induces Phosphorylation-Mediated Signaling that Underlies Tissue Response and Robustness in Xenopus Embryos.Yutaka Hashimoto et al.Cell systems, 8(3), 226-241 (2019-03-11) The role of focal adhesion kinase in transforming growth factor-β2 induced migration of human lens epithelial cells.Jie Liu et al.International journal of molecular medicine, 42(6), 3591-3601 (2018-10-04) Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin.Dieter Rondas et al.Diabetes, 60(4), 1146-1157 (2011-03-02) Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.Daisuke Aoyama et al.PloS one, 8(11), e81133-e81133 (2013-11-28) Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts.Laura L Stafman et al.Scientific reports, 9(1), 13259-13259 (2019-09-15) In vivo toxicity, metabolism and pharmacokinetic properties of FAK inhibitor 14 or Y15 (1, 2, 4, 5-benzenetetramine tetrahydrochloride).Vita Golubovskaya et al.Archives of toxicology, 89(7), 1095-1101 (2014-06-12) Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors.Friedrich Erhart et al.NPJ vaccines, 5, 5-5 (2020-01-24) On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing.Ayman Husari et al.Cellular signalling, 63, 109382-109382 (2019-08-04) CD44-Targeting PLGA Nanoparticles Incorporating Paclitaxel and FAK siRNA Overcome Chemoresistance in Epithelial Ovarian Cancer.Yeongseon Byeon et al.Cancer research, 78(21), 6247-6256 (2018-08-18) Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.Vita Golubovskaya et al.Journal of cancer research and clinical oncology, 141(9), 1613-1631 (2015-02-07) Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma.Arun Kumar Nalla et al.PloS one, 5(9), e13006-e13006 (2010-10-05) Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling.Ali M Ethaeb et al.Apoptosis : an international journal on programmed cell death, 25(1-2), 29-41 (2019-10-28) Regulators of Intestinal Epithelial Migration in Sepsis.Mei Meng et al.Shock (Augusta, Ga.), 51(1), 88-96 (2018-02-10) Photocatalytic oxygen evolution from low-bandgap conjugated microporous polymer nanosheets: a combined first-principles calculation and experimental study.Lei Wang et al.Nanoscale, 9(12), 4090-4096 (2017-03-16) Conductive Metal-Organic Frameworks with Extra Metallic Sites as an Efficient Electrocatalyst for the Hydrogen Evolution Reaction.Hao Huang et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(9), 2000012-2000012 (2020-05-10) CEACAM6 promotes tumor angiogenesis and vasculogenic mimicry in gastric cancer via FAK signaling.Mingde Zang et al.Biochimica et biophysica acta, 1852(5), 1020-1028 (2015-02-24) FAK is a critical regulator of neuroblastoma liver metastasis.Sora Lee et al.Oncotarget, 3(12), 1576-1587 (2012-12-06) Azo dyes in clothing textiles can be cleaved into a series of mutagenic aromatic amines which are not regulated yet.Beat J Brüschweiler et al.Regulatory toxicology and pharmacology : RTP, 88, 214-226 (2017-06-29) Contribution of activated beta3 integrin in the PDI release from endothelial cells.Halszka Ponamarczuk et al.Frontiers in bioscience (Landmark edition), 23, 1612-1627 (2018-01-03)

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