没有数据	没有数据

没有数据	没有数据

Source	SDS/MSDS Samples
Matrix	View & Download
Combi-Blocks	View & Download

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Difference in Developmental Kinetics of Y-Specific Monoclonal Antibody Sorted Male and Female In Vitro Produced Bovine Embryos.Tabinda Sidrat et al.International journal of molecular sciences, 21(1) (2020-01-08) Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells.Tingyan Hu et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 127, 188-196 (2019-03-25) Serine is required for the maintenance of redox balance and proliferation in the intestine under oxidative stress.Liuqin He et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4702-4717 (2020-02-08) Adenosine AJingman Xu et al.Free radical biology & medicine, 106, 208-218 (2017-02-22) Cytotoxicity of Saikosaponin A targets HEKa cell through apoptosis induction by ROS accumulation and inflammation suppression via NF-κB pathway.Meng Liu et al.International immunopharmacology, 86, 106751-106751 (2020-07-08) Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative stress.Jiahong Zhong et al.Redox biology, 16, 47-58 (2018-02-24) The beneficial effects of resveratrol on steatosis and mitochondrial oxidative stress in HepG2 cells.Magdalena Izdebska et al.Canadian journal of physiology and pharmacology, 95(12), 1442-1453 (2017-08-02) Tanshinone IIa protects retinal endothelial cells against mitochondrial fission induced by methylglyoxal through glyoxalase 1.Shuhong Qian et al.European journal of pharmacology, 857, 172419-172419 (2019-05-29) The protective effect of propofol against TNF-α-induced apoptosis was mediated via inhibiting iNOS/NO production and maintaining intracellular CaZheng Xu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 91, 664-672 (2017-05-13) Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.Babak Baban et al.PloS one, 10(4), e0124059-e0124059 (2015-04-23) Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.Hiroaki Goto et al.Cancer chemotherapy and pharmacology, 85(4), 773-783 (2020-03-08) The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.Yi-Hua Sheng et al.Molecules (Basel, Switzerland), 25(12) (2020-07-08) Apatinib, a novel tyrosine kinase inhibitor, suppresses tumor growth in cervical cancer and synergizes with Paclitaxel.Haifeng Qiu et al.Cell cycle (Georgetown, Tex.), 17(10), 1235-1244 (2018-06-12) Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.Zixuan Liu et al.Chemical research in toxicology, 30(10), 1804-1814 (2017-08-22) Qian Li et al.Infectious diseases (London, England), 51(11-12), 793-801 (2019-08-15)Background:Porphyromonas gingivalis, a major pathogen of chronic periodontitis, adheres to and invades epithelial cells via an interaction between fimbriae and integrin. P. gingivalis proliferation and infection may affect the survival of cells. In this study, we further examined alternative signaling... Rapid thawing and stabilizing procedure improve postthaw survival and in vitro penetrability of boar spermatozoa cryopreserved with a glycerol-free trehalose-based extender.Rukmali Athurupana et al.Theriogenology, 84(6), 940-947 (2015-07-02) Baicalein protects tert‑butyl hydroperoxide‑induced hepatotoxicity dependent of reactive oxygen species removal.Ya-Fang Wang et al.Molecular medicine reports, 16(6), 8392-8398 (2017-09-26) Garcinia xanthochymus extract protects PC12 cells from HJing Xu et al.Chinese journal of natural medicines, 15(11), 825-833 (2018-01-14) Fucoidan inhibits the proliferation of human urinary bladder cancer T24 cells by blocking cell cycle progression and inducing apoptosis.Hye Young Park et al.Molecules (Basel, Switzerland), 19(5), 5981-5998 (2014-05-14) XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis.Zhi-Chuan Zhu et al.Cell death & disease, 10(6), 395-395 (2019-05-23) ROS-mediated activation of AMPK plays a critical role in sulforaphane-induced apoptosis and mitotic arrest in AGS human gastric cancer cells.Yung H Choi General physiology and biophysics, 37(2), 129-140 (2018-03-30) The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748.Barbara Borowa-Mazgaj et al.Biochemical pharmacology, 142, 21-38 (2017-06-25) Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells.Kai Jiang et al.Oncology reports, 33(6), 2711-2718 (2015-04-22) MTERF4 regulates the mitochondrial dysfunction induced by MPP(+) in SH-SY5Y cells.Xiaofei Ye et al.Biochemical and biophysical research communications, 464(1), 214-220 (2015-06-24) Osteochondritis Dissecans (OCD)-Derived Chondrocytes Display Increased Senescence, Oxidative Stress, Chaperone-Mediated Autophagy and, in Co-Culture with Adipose-Derived Stem Cells (ASCs), Enhanced Expression of MMP-13.Katarzyna Kornicka et al.Journal of clinical medicine, 8(3) (2019-03-13) Apoptosis signal-regulating kinase 1 promotes Ochratoxin A-induced renal cytotoxicity.Rui Liang et al.Scientific reports, 5, 8078-8078 (2015-01-30) Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway.Pei Zhang et al.Gene, 745, 144623-144623 (2020-03-31) Lycopene alleviates AFB1-induced immunosuppression by inhibiting oxidative stress and apoptosis in the spleen of mice.Feibo Xu et al.Food & function, 10(7), 3868-3879 (2019-06-12) Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells.Neha Kaushik et al.Scientific reports, 5, 8726-8726 (2015-03-05) Ursodeoxycholyl lysophosphatidylethanolamide protects against hepatic ischemia/reperfusion injury via phospholipid metabolism-mediated mitochondrial quality control.Jian Gu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6198-6214 (2020-03-13) Inhibition of NAMPT markedly enhances plasma-activated medium-induced cell death in human breast cancer MDA-MB-231 cells.Misaki Nagaya et al.Archives of biochemistry and biophysics, 676, 108155-108155 (2019-10-20) Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity.Xiao-Yun Liu et al.Cell death & disease, 9(6), 610-610 (2018-05-26) Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.Min Ho Han et al.Drug development research, 78(1), 37-48 (2016-09-23) Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis.Ruilong Li et al.Biochemical and biophysical research communications, 529(1), 15-22 (2020-06-21) Regulation and actions of activin A and follistatin in myocardial ischaemia-reperfusion injury.Yi Chen et al.Cytokine, 69(2), 255-262 (2014-07-24) BAFF attenuates oxidative stress-induced cell death by the regulation of mitochondria membrane potential via Syk activation in WiL2-NS B lymphoblasts.Sojin Park et al.Scientific reports, 10(1), 11784-11784 (2020-07-18) Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects.Francesco Paolo Intini et al.Inorganic chemistry, 56(3), 1483-1497 (2017-01-20) Elatoside C protects against hypoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes through the reduction of endoplasmic reticulum stress partially depending on STAT3 activation.Min Wang et al.Apoptosis : an international journal on programmed cell death, 19(12), 1727-1735 (2014-10-19) Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotic effects in A549 lung cancer cell lines.Qing-Lin Niu et al.PloS one, 15(5), e0231437-e0231437 (2020-05-02) Sulfur dioxide induces apoptosis via reactive oxygen species generation in rat cardiomyocytes.Shuyue Li et al.Environmental science and pollution research international, 26(9), 8758-8767 (2019-02-04) Bisphenol A suppresses proliferation and induces apoptosis in colonic epithelial cells through mitochondrial and MAPK/AKT pathways.Wei Qu et al.Life sciences, 208, 167-174 (2018-07-24) Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.Sung-Kyun Ko et al.Nature chemistry, 6(10), 885-892 (2014-09-23) Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells.Yisen Cheng et al.Toxicology letters, 292, 136-150 (2018-05-04) β-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway.Daoju Gan et al.Oncology letters, 19(1), 291-300 (2020-01-04) Knockout serum replacement is an efficient serum substitute for cryopreservation of human spermatozoa.Seyed Mohamad Javad Taher-Mofrad et al.Cryobiology, 92, 208-214 (2020-02-01) Schizandra chinensis extracts induce apoptosis in human gastric cancer cells via JNK/p38 MAPK activation and the ROS-mediated/mitochondria-dependent pathway.Hyun Sul Kim et al.Pharmaceutical biology, 53(2), 212-219 (2014-09-23) Combined cell death of co-exposure to aldehyde mixtures on human bronchial epithelial BEAS-2B cells: Molecular insights into the joint action.Sen Zhang et al.Chemosphere, 244, 125482-125482 (2019-12-10) NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.Carolina Hassibe Thomé et al.Scientific reports, 10(1), 10315-10315 (2020-06-27) MiR-363 sensitizes cisplatin-induced apoptosis targeting in Mcl-1 in breast cancer.Ruiguang Zhang et al.Medical oncology (Northwood, London, England), 31(12), 347-347 (2014-11-25) Quercetin supplemented casein-based extender improves the post-thaw quality of rooster semen.Michael Osei Appiah et al.Cryobiology, 94, 57-65 (2020-05-22) Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression.Bin Zhang et al.Molecules (Basel, Switzerland), 24(2) (2019-01-13) Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells.Jin Seok et al.Stem cell research & therapy, 11(1), 1-1 (2020-01-05) Deoxynucleosides with benzimidazoles as aglycone moiety are potent anticancer agents.Mirosława Koronkiewicz et al.European journal of pharmacology, 820, 146-155 (2017-12-17) Perfluoro-octanoic acid impairs sperm motility through the alteration of plasma membrane.I Šabović et al.Journal of endocrinological investigation, 43(5), 641-652 (2019-11-30) Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death.Hyun Kyung Park et al.International journal of molecular sciences, 21(7) (2020-04-16) Artesunate induces apoptosis through caspase-dependent and -independent mitochondrial pathways in human myelodysplastic syndrome SKM-1 cells.Ying Wang et al.Chemico-biological interactions, 219, 28-36 (2014-04-08) Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.Tahir Mehmood et al.Journal of Cancer, 8(18), 3707-3717 (2017-11-21) DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.Qian Zhang et al.The Journal of experimental medicine, 211(13), 2549-2566 (2014-11-26) A novel chalcone derivative S17 induces apoptosis through ROS dependent DR5 up-regulation in gastric cancer cells.Saiyang Zhang et al.Scientific reports, 7(1), 9873-9873 (2017-08-31) Gallic acid caused cultured mice TM4 Sertoli cells apoptosis and necrosis.Wanhong Li et al.Asian-Australasian journal of animal sciences, 32(5), 629-636 (2018-11-02) Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons.Kaihua Wang et al.International journal of molecular medicine, 40(5), 1582-1590 (2017-09-28) FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway.Lihua Cui et al.Life sciences, 217, 243-250 (2018-12-15) EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells.Ju-Hee Lee et al.Oncotarget, 6(12), 9701-9717 (2015-05-21) Short-term exposure to ZnO/MCB persistent free radical particles causes mouse lung lesions via inflammatory reactions and apoptosis pathways.Xing Zhang et al.Environmental pollution (Barking, Essex : 1987), 261, 114039-114039 (2020-03-30) Urban particulate matter disturbs the equilibrium of mitochondrial dynamics and biogenesis in human vascular endothelial cells.Yan Wang et al.Environmental pollution (Barking, Essex : 1987), 264, 114639-114639 (2020-05-11) 2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1).Jie Yu et al.Free radical biology & medicine, 152, 336-347 (2020-04-03) The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis.Jiankai Zhong et al.Aging, 12(13), 13618-13632 (2020-07-10) Sonodynamic therapy in atherosclerosis by curcumin nanosuspensions: Preparation design, efficacy evaluation, and mechanisms analysis.Lei Jiang et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 101-110 (2019-12-17) Escin induces apoptosis in human bladder cancer cells: An in vitro and in vivo study.Chen-Li Cheng et al.European journal of pharmacology, 840, 79-88 (2018-10-06) A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.Jingwen Xu et al.Steroids, 161, 108672-108672 (2020-06-03) Inverse opal substrate-loaded mesenchymal stem cells contribute to decreased myocardial remodeling after transplantation into acute myocardial infarction mice.Wenbin Lu et al.International journal of nanomedicine, 13, 7033-7046 (2018-11-23) Altered cellular metabolism of HepG2 cells caused by microcystin-LR.Junguo Ma et al.Environmental pollution (Barking, Essex : 1987), 225, 610-619 (2017-03-25) Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage.Xiaojuan Qie et al.Frontiers in pharmacology, 8, 639-639 (2017-09-30) Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity.Leonel A Cortes et al.PloS one, 10(8), e0136852-e0136852 (2015-09-01) Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways.Jiumao Lin et al.BMC cancer, 14, 729-729 (2014-10-01) Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells.Yuefan Ma et al.Oncology reports, 39(6), 2899-2905 (2018-04-06) Targeting cyclophilin-D by compound 19 protects neuronal cells from oxygen glucose deprivation/re-oxygenation.Jinyu Zheng et al.Oncotarget, 8(52), 90238-90249 (2017-11-23) Lycopene Inhibits Reactive Oxygen Species-Mediated NF-κB Signaling and Induces Apoptosis in Pancreatic Cancer Cells.Yoonseon Jeong et al.Nutrients, 11(4) (2019-04-04) The effect of two packaging systems on the post-thaw characteristics of canine sperm.R Strzeżek et al.Polish journal of veterinary sciences, 18(2), 249-253 (2015-07-15) A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse.Radovan Krejcir et al.International journal of molecular sciences, 20(17) (2019-08-31) Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways.Ruixue Xia et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(3), 987-998 (2017-07-01) Ganoderic acid A exerts antitumor activity against MDA-MB-231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway.Yuguang Yang et al.Oncology letters, 16(5), 6515-6521 (2018-11-09) Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-β/STAT3 Pathway.Zhenghuan Fang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(5), 1751-1768 (2018-06-29) Physakengose G induces apoptosis via EGFR/mTOR signaling and inhibits autophagic flux in human osteosarcoma cells.Hua Lin et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 42, 190-198 (2018-04-16) Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization.Yuta Kanamori et al.Experimental and therapeutic medicine, 19(2), 1511-1521 (2020-02-06) Cytoplasmic upregulation of Cyto c and AIF serve as biomarkers of mechanical asphyxia death.Heng Zhang et al.American journal of translational research, 11(7), 4568-4583 (2019-08-10) Comparison of changes in mitochondrial bioenergetics between keratinocytes in human external auditory canal skin and cholesteatomas from normoxia to hypoxia.Cheng-Ping Shih et al.Scientific reports, 8(1), 125-125 (2018-01-11) Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway.Dhiraj Kumar et al.BMC cancer, 18(1), 52-52 (2018-01-10) Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.Guiping Cai et al.European journal of medicinal chemistry, 174, 236-251 (2019-05-03) SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy.Yiyang Wang et al.Aging, 12(16), 16126-16141 (2020-07-21) Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells.Yapeng Lu et al.Biochemical and biophysical research communications, 519(1), 153-159 (2019-09-05) Hyperbaric Oxygen Ameliorated Acute Pancreatitis in Rats via the Mitochondrial Pathway.He Zhao et al.Digestive diseases and sciences, 65(12), 3558-3569 (2020-02-02) High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway.Guo-Sheng Zhao et al.American journal of translational research, 11(4), 2117-2139 (2019-05-21) Obacunone attenuates high glucose-induced oxidative damage in NRK-52E cells by inhibiting the activity of GSK-3β.Jie Zhou et al.Biochemical and biophysical research communications, 513(1), 226-233 (2019-04-08) Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway.Zhiyun Cao et al.Molecular medicine reports, 12(2), 2800-2806 (2015-05-06) JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1.Jiong Yang et al.International journal of molecular sciences, 16(10), 25744-25758 (2015-10-31) TiO2 Nanotubes Alleviate Diabetes-Induced Osteogenetic Inhibition.Jinghong Yang et al.International journal of nanomedicine, 15, 3523-3537 (2020-06-18) Erianin protects against high glucose-induced oxidative injury in renal tubular epithelial cells.Mei-Fen Chen et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 126, 97-105 (2019-02-15) Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.Zhong Wang et al.Translational stroke research, 9(1), 74-91 (2017-08-03) Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.J Abdi et al.The Journal of nutritional biochemistry, 25(12), 1254-1262 (2014-10-04) Induction of autophagy, apoptosis and aquisition of resistance in response to piceatannol toxicity in MOLT-4 human leukemia cells.Kamila Siedlecka-Kroplewska et al.Toxicology in vitro : an international journal published in association with BIBRA, 59, 12-25 (2019-04-04) Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.Junying Wang et al.Aging, 12(1), 650-671 (2020-01-08) Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality.Akwasi Atakora Amoako et al.Fertility and sterility, 102(5), 1260-1267 (2014-09-13) Compound K inhibits autophagy-mediated apoptosis induced by oxygen and glucose deprivation/reperfusion via regulating AMPK-mTOR pathway in neurons.Qingxia Huang et al.Life sciences, 254, 117793-117793 (2020-05-18) Butylparaben Is Toxic to Porcine Oocyte Maturation and Subsequent Embryonic Development Following In Vitro Fertilization.Pil-Soo Jeong et al.International journal of molecular sciences, 21(10) (2020-05-28) Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy.Jae Woong Han et al.International journal of nanomedicine, 12, 7529-7549 (2017-10-27) Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.Kirsten L Bryant et al.Nature medicine, 25(4), 628-640 (2019-03-06) Effects of resveratrol, granulocyte-macrophage colony-stimulating factor or dichloroacetic acid in the culture media on embryonic development and pregnancy rates in aged mice.Jeong Yoon et al.Aging, 12(3), 2659-2669 (2020-02-07) Tanshinone IIA induces apoptosis via inhibition of Wnt/β‑catenin/MGMT signaling in AtT‑20 cells.Zong-Yang Li et al.Molecular medicine reports, 16(5), 5908-5914 (2017-08-30) CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.Wenlong Zhang et al.Theranostics, 10(7), 3000-3021 (2020-03-21) Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro.Shigeru Murakami et al.Amino acids, 50(9), 1279-1288 (2018-06-28) Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice.Belén Mollá et al.Frontiers in molecular neuroscience, 10, 264-264 (2017-09-16) Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy.Hua Bai et al.Neurochemistry international, 134, 104671-104671 (2020-01-12) Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease.Chunyue Wang et al.International journal of molecular medicine, 43(2), 956-966 (2018-12-21) Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate.Jarmila Navrátilová et al.Journal of cellular and molecular medicine, 21(9), 1859-1869 (2017-03-01) LncRNA-uc.40 silence promotes P19 embryonic cells differentiation to cardiomyocyte via the PBX1 gene.Rongqiang Wu et al.In vitro cellular & developmental biology. Animal, 54(8), 600-609 (2018-08-17) Effect of Aruncus dioicus var. kamtschaticus Extract on Neurodegeneration Improvement: Ameliorating Role in Cognitive Disorder Caused by High-Fat Diet Induced Obesity.Su Bin Park et al.Nutrients, 11(6) (2019-06-20) Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes.Tatyana G Pekun et al.SpringerPlus, 3, 560-560 (2014-10-22) Betulin exhibits anti-inflammatory activity in LPS-stimulated macrophages and endotoxin-shocked mice through an AMPK/AKT/Nrf2-dependent mechanism.Xinxin Ci et al.Cell death & disease, 8(5), e2798-e2798 (2017-05-19) Sulforaphene inhibits esophageal cancer progression via suppressing SCD and CDH3 expression, and activating the GADD45B-MAP2K3-p38-p53 feedback loop.Sichong Han et al.Cell death & disease, 11(8), 713-713 (2020-09-03) Ginsenoside compound K protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury via inhibition of nuclear factor-κB, p38, and JNK MAPK pathways.Shan Lu et al.Journal of ginseng research, 43(1), 95-104 (2019-01-22) ROS-Mediated Necroptosis Is Involved in Iron Overload-Induced Osteoblastic Cell Death.Qing Tian et al.Oxidative medicine and cellular longevity, 2020, 1295382-1295382 (2020-10-31) Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits.Jing Wu et al.Journal of neuroinflammation, 17(1), 110-110 (2020-04-12) Autophagy activation promotes removal of damaged mitochondria and protects against renal tubular injury induced by albumin overload.Jin Tan et al.Histology and histopathology, 33(7), 681-690 (2018-01-11) Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential.He Liu et al.Cell death and differentiation, 26(6), 1048-1061 (2018-08-30) Nucleobase-modified polyamidoamine-mediated miR-23b delivery to inhibit the proliferation and migration of lung cancer.Haobo Han et al.Biomaterials science, 5(11), 2268-2275 (2017-10-05) Long non-coding RNA LINC01419 mediates miR-519a-3p/PDRG1 axis to promote cell progression in osteosarcoma.Zhiqian Gu et al.Cancer cell international, 20, 147-147 (2020-05-12) Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy.Manisha Ahir et al.Biomaterials science, 8(10), 2939-2954 (2020-04-23) Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation.Rita U Ostrovskaya et al.Journal of biomedical science, 21, 74-74 (2014-08-07) RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics.Youlim Hong et al.Cell death and differentiation, 27(5), 1633-1643 (2019-10-30) The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction.Yun-Ju Wang et al.Toxicology and applied pharmacology, 402, 115133-115133 (2020-07-16) J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential.M Reers et al.Biochemistry, 30(18), 4480-4486 (1991-05-07) Hippo/Mst1 overexpression induces mitochondrial death in head and neck squamous cell carcinoma via activating β-catenin/Drp1 pathway.Chao Ma et al.Cell stress & chaperones, 24(4), 807-816 (2019-05-28) The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells.Ewa Augustin et al.Acta pharmacologica Sinica, 36(3), 385-399 (2015-02-03) Mitoxantrone as photothermal agents for ultrasound/fluorescence imaging-guided chemo-phototherapy enhanced by intratumoral H2O2-Induced CO.Ya Wang et al.Biomaterials, 252, 120111-120111 (2020-05-19) Mn-TAT PTD-Ngb ameliorates inflammation through the elimination of damaged mitochondria and the activation of Nrf2-antioxidant signaling pathway.Cui Zhang et al.Biochemical pharmacology, 178, 114055-114055 (2020-05-30) Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells.Marina Figliuzzi et al.Archives of toxicology, 94(9), 2965-2979 (2020-06-25) Suppression of HAX-1 induced by miR-325 resensitizes bladder cancer cells to cisplatin-induced apoptosis.R Li et al.European review for medical and pharmacological sciences, 24(18), 9303-9314 (2020-10-06) Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein.Shuichi Sekine et al.Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30) Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines.Hamideh Abedi et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(11), 11027-11039 (2014-08-07) Curcumin inhibits appoptosin-induced apoptosis via upregulating heme oxygenase-1 expression in SH-SY5Y cells.Kun-mu Zheng et al.Acta pharmacologica Sinica, 36(5), 544-552 (2015-04-22) CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk.Pinjia Chen et al.Free radical biology & medicine, 104, 280-297 (2017-01-31) T59, a New Compound Reconstructed from Curcumin, Induces Cell Apoptosis through Reactive Oxygen Species Activation in Human Lung Cancer Cells.Zhendong Zhao et al.Molecules (Basel, Switzerland), 23(6) (2018-06-09) N-Isopropylacrylamide-modified polyethylenimine-mediated p53 gene delivery to prevent the proliferation of cancer cells.Jianxu Zhang et al.Colloids and surfaces. B, Biointerfaces, 129, 54-62 (2015-04-02) Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice.Dongtao Wang et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 75(11), 2081-2088 (2020-08-29) Icariin may benefit the mesenchymal stem cells of patients with steroid-associated osteonecrosis by ABCB1-promoter demethylation: a preliminary study.Z-B Sun et al.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 26(1), 187-197 (2014-08-13) Amyloid-β25-35 Upregulates Endogenous Neuroprotectant Neuroglobin via NFκB Activation in vitro.Ning Liu et al.Journal of Alzheimer's disease : JAD, 64(4), 1163-1174 (2018-07-17) KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.Zhi-Chuan Zhu et al.Oncogene, 37(22), 2936-2952 (2018-03-10) Design, synthesis and evaluation of 3-arylidene azetidin-2-ones as potential antifungal agents against Alternaria solani Sorauer.Wang Delong et al.Bioorganic & medicinal chemistry, 25(24), 6661-6673 (2017-11-16) Involvement of autophagy in cordycepin-induced apoptosis in human prostate carcinoma LNCaP cells.Hye Hyeon Lee et al.Environmental toxicology and pharmacology, 38(1), 239-250 (2014-06-29) Apoptosis effects of imperatorin on synoviocytes in rheumatoid arthritis through mitochondrial/caspase-mediated pathways.Ke-Feng Zhai et al.Food & function, 9(4), 2070-2079 (2018-03-27) Selenocysteine inhibits human osteosarcoma cells growth through triggering mitochondrial dysfunction and ROS-mediated p53 phosphorylation.Wei Wang et al.Cell biology international, 42(5), 580-588 (2018-01-13) Persistent mitoKYan Yang et al.Molecular neurobiology, 54(2), 1101-1110 (2016-01-25) Activation of the Nrf2/HO-1 Signaling Pathway Contributes to the Protective Effects of Sargassum serratifolium Extract against Oxidative Stress-Induced DNA Damage and Apoptosis in SW1353 Human Chondrocytes.Cheol Park et al.International journal of environmental research and public health, 15(6) (2018-06-08) Biochanin A Induces S Phase Arrest and Apoptosis in Lung Cancer Cells.Yan Li et al.BioMed research international, 2018, 3545376-3545376 (2018-11-08) Antitumor effects of Xi Huang pills on MDA‑MB‑231 cells in vitro and in vivo.Wenxian Zheng et al.Molecular medicine reports, 18(2), 2068-2078 (2018-06-30) Artemisinin Attenuated Hydrogen Peroxide (H2O2)-Induced Oxidative Injury in SH-SY5Y and Hippocampal Neurons via the Activation of AMPK Pathway.Xia Zhao et al.International journal of molecular sciences, 20(11) (2019-06-04) Extracellular vesicle-encapsulated IL-10 as novel nanotherapeutics against ischemic AKI.Tao-Tao Tang et al.Science advances, 6(33), eaaz0748-eaaz0748 (2020-08-28) DPP-4 Inhibitor Linagliptin Attenuates Aβ-induced Cytotoxicity through Activation of AMPK in Neuronal Cells.Edy Kornelius et al.CNS neuroscience & therapeutics, 21(7), 549-557 (2015-05-27) α-Hederin induces the apoptosis of gastric cancer cells accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway.Jing Wang et al.Phytotherapy research : PTR, 34(3), 601-611 (2019-11-30) MicroRNA-143 promotes cardiac ischemia-mediated mitochondrial impairment by the inhibition of protein kinase Cepsilon.Hong Hong et al.Basic research in cardiology, 112(6), 60-60 (2017-09-10) Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.Huanliang Liu et al.Journal of hazardous materials, 392, 122312-122312 (2020-02-28) A small-molecule activator of mitochondrial aldehyde dehydrogenase 2 reduces the severity of cerulein-induced acute pancreatitis.Shengchuan Cao et al.Biochemical and biophysical research communications, 522(2), 518-524 (2019-12-01) Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels.Mustafa Nazıroğlu et al.PloS one, 12(6), e0179950-e0179950 (2017-06-24) Isorhamnetin Protects Human Keratinocytes against Ultraviolet B-Induced Cell Damage.Xia Han et al.Biomolecules & therapeutics, 23(4), 357-366 (2015-07-15) Natural compound Alternol induces oxidative stress-dependent apoptotic cell death preferentially in prostate cancer cells.Yuzhe Tang et al.Molecular cancer therapeutics, 13(6), 1526-1536 (2014-04-02) Vitamin D3 affects mitochondrial biogenesis through mitogen-activated protein kinase in polycystic ovary syndrome mouse model.Zahra Safaei et al.Journal of cellular physiology, 235(9), 6113-6126 (2020-02-13) Analgesic effect of Photobiomodulation Therapy: An in vitro and in vivo study.Luisa Zupin et al.Journal of biophotonics, 12(10), e201900043-e201900043 (2019-06-21) 5,7-Dimethoxyflavone induces apoptotic cell death in human endometriosis cell lines by activating the endoplasmic reticulum stress pathway.Wonhyoung Park et al.Phytotherapy research : PTR, 34(9), 2275-2286 (2020-03-20) Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma.Zhen Dong et al.British journal of cancer, 116(12), 1572-1584 (2017-05-12) Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes.Dmitry E Andreev et al.Genome biology, 16, 90-90 (2015-05-07) Total flavones of Dracocephalum moldavica L. protect astrocytes against H2O2-induced apoptosis through a mitochondria-dependent pathway.Rui-Fang Zheng et al.BMC complementary medicine and therapies, 20(1), 78-78 (2020-03-14) Oxidative stress and cell cycle arrest induced by short-term exposure to dustfall PM2.5 in A549 cells.Jie Yang et al.Environmental science and pollution research international, 25(23), 22408-22419 (2017-11-04) Taxifolin synergizes Andrographolide-induced cell death by attenuation of autophagy and augmentation of caspase dependent and independent cell death in HeLa cells.Mazen Alzaharna et al.PloS one, 12(2), e0171325-e0171325 (2017-02-10) LncRNA FOXP4-AS1 is activated by PAX5 and promotes the growth of prostate cancer by sequestering miR-3184-5p to upregulate FOXP4.Xingcheng Wu et al.Cell death & disease, 10(7), 472-472 (2019-06-19) A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis.Jessica K T Sousa et al.Parasitology international, 73, 101966-101966 (2019-07-31) Mitochondrial delivery of antisense RNA by MITO-Porter results in mitochondrial RNA knockdown, and has a functional impact on mitochondria.Ryo Furukawa et al.Biomaterials, 57, 107-115 (2015-04-29) Pyocyanin induces NK92 cell apoptosis via mitochondrial damage and elevated intracellular Ca2.Ting Li et al.Innate immunity, 25(1), 3-12 (2018-11-15) Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action.Anissa Nofita Sari et al.Cancers, 12(5) (2020-05-10) Paracrine Anti-inflammatory Effects of Adipose Tissue-Derived Mesenchymal Stem Cells in Human Monocytes.Maria I Guillén et al.Frontiers in physiology, 9, 661-661 (2018-06-16) Resveratrol improves intestinal barrier function, alleviates mitochondrial dysfunction and induces mitophagy in diquat challenged piglets1.Shuting Cao et al.Food & function, 10(1), 344-354 (2019-01-03) Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27.Sung Won Lee et al.Bone research, 6, 20-20 (2018-07-14) Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells.Shuangyue Li et al.Industrial health, 55(2), 108-118 (2016-11-15) Transcranial low-level laser therapy improves brain mitochondrial function and cognitive impairment in D-galactose-induced aging mice.Farzad Salehpour et al.Neurobiology of aging, 58, 140-150 (2017-07-25) PERK pathway is involved in oxygen-glucose-serum deprivation-induced NF-kB activation via ROS generation in spinal cord astrocytes.Jinbo Liu et al.Biochemical and biophysical research communications, 467(2), 197-203 (2015-10-11) Attenuation of cyclosporine A induced nephrotoxicity by schisandrin B through suppression of oxidative stress, apoptosis and autophagy.Qiao Lai et al.International immunopharmacology, 52, 15-23 (2017-08-29) Development of erianin-loaded dendritic mesoporous silica nanospheres with pro-apoptotic effects and enhanced topical delivery.Canlong Mo et al.Journal of nanobiotechnology, 18(1), 55-55 (2020-04-02) Potent hydrazone derivatives targeting esophageal cancer cells.Ling-Yu Li et al.European journal of medicinal chemistry, 148, 359-371 (2018-02-24) Intravenous administration of mitochondria for treating experimental Parkinson's disease.Xianxun Shi et al.Mitochondrion, 34, 91-100 (2017-03-01) Wogonoside promotes apoptosis in gastric cancer AGS and SGC-7901 cells through induction of mitochondrial dysfunction and endoplasmic reticulum stress.Xiao-Miao Hu et al.FEBS open bio, 9(8), 1469-1476 (2019-06-30) Investigating the role of Sirt1-modulated oxidative stress in relation to benign paroxysmal positional vertigo and Parkinson's disease.Kun-Ling Tsai et al.Neurobiology of aging, 36(9), 2607-2616 (2015-07-02) Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation.Ganesh M Mohite et al.Biochemistry, 57(35), 5183-5187 (2018-05-18) Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Aβ-Induced Cognitive Impairment in Vivo.Jun Yan et al.ACS chemical neuroscience, 10(6), 2903-2914 (2019-05-01) Hypoxia induces lactate secretion and glycolytic efflux by downregulating mitochondrial pyruvate carrier levels in human umbilical vein endothelial cells.Dong Wang et al.Molecular medicine reports, 18(2), 1710-1717 (2018-05-31) Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.Lulu Chen et al.American journal of translational research, 12(2), 428-446 (2020-03-21) A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer.Huihui Bu et al.International journal of pharmaceutics, 471(1-2), 206-213 (2014-05-29) Ginsenoside Rg3 restores hepatitis C virus-induced aberrant mitochondrial dynamics and inhibits virus propagation.Seong-Jun Kim et al.Hepatology (Baltimore, Md.), 66(3), 758-771 (2017-03-23) Drug-free macromolecular therapeutics exhibit amplified apoptosis in G2/M phase arrested cells.Lian Li et al.Journal of drug targeting, 27(5-6), 566-572 (2018-09-11) Dietary Tributyrin Attenuates Intestinal Inflammation, Enhances Mitochondrial Function, and Induces Mitophagy in Piglets Challenged with Diquat.Chunchun Wang et al.Journal of agricultural and food chemistry, 67(5), 1409-1417 (2019-01-03) Early prepubertal cyclophosphamide exposure in mice results in long-term loss of ovarian reserve, and impaired embryonic development and blastocyst quality.Sujith Raj Salian et al.PloS one, 15(6), e0235140-e0235140 (2020-06-24) The mitochondrial-targeted peptide SBT-20 ameliorates inflammation and oxidative stress in chronic renal failure.Lina Sun et al.Aging, 12(18), 18238-18250 (2020-09-27) Caffeic acid phenethyl ester against cadmium induced toxicity mediated by CircRNA modulates autophagy in HepG2 cells.Rili Hao et al.Ecotoxicology and environmental safety, 197, 110610-110610 (2020-04-17) TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells.Ján Remšík et al.Scientific reports, 10(1), 11396-11396 (2020-07-11) Rapid isolation and purification of functional platelet mitochondria using a discontinuous Percoll gradient.Jacob L Léger et al.Platelets, 31(2), 258-264 (2019-05-07) Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.Seog-Young Kim et al.Apoptosis : an international journal on programmed cell death, 19(11), 1603-1615 (2014-08-27) Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury.Wei Chen et al.Theranostics, 10(13), 5879-5894 (2020-06-03) Dietary Tributyrin Attenuates Intestinal Inflammation, Enhances Mitochondrial Function, and Induces Mitophagy in Piglets Challenged with Diquat.Chunchun Wang et al.Journal of agricultural and food chemistry, 67(5), 1409-1417 (2019-01-03) Actinomycin D synergistically enhances the cytotoxicity of CDDP on KB cells by activating P53 via decreasing P53-MDM2 complex.Lin Wang et al.Journal of Asian natural products research, 19(6), 630-643 (2017-04-26) Early prepubertal cyclophosphamide exposure in mice results in long-term loss of ovarian reserve, and impaired embryonic development and blastocyst quality.Sujith Raj Salian et al.PloS one, 15(6), e0235140-e0235140 (2020-06-24) Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.Xihong Liu et al.Journal of experimental & clinical cancer research : CR, 38(1), 184-184 (2019-05-06) Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis.Ruilong Li et al.Biochemical and biophysical research communications, 529(1), 15-22 (2020-06-21) In vitro apoptotic mechanism of a novel synthetic Quinazolinyl derivative: Induces caspase-dependent intrinsic pathway on THP-1, leukemia cell line.Sridhar Vakamullu et al.Chemico-biological interactions, 280, 117-127 (2017-12-12) Regulation and actions of activin A and follistatin in myocardial ischaemia-reperfusion injury.Yi Chen et al.Cytokine, 69(2), 255-262 (2014-07-24) BAFF attenuates oxidative stress-induced cell death by the regulation of mitochondria membrane potential via Syk activation in WiL2-NS B lymphoblasts.Sojin Park et al.Scientific reports, 10(1), 11784-11784 (2020-07-18) Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects.Francesco Paolo Intini et al.Inorganic chemistry, 56(3), 1483-1497 (2017-01-20) Inhibition of NAMPT markedly enhances plasma-activated medium-induced cell death in human breast cancer MDA-MB-231 cells.Misaki Nagaya et al.Archives of biochemistry and biophysics, 676, 108155-108155 (2019-10-20) MITF acts as an anti-oxidant transcription factor to regulate mitochondrial biogenesis and redox signaling in retinal pigment epithelial cells.Jiajia Hua et al.Experimental eye research, 170, 138-147 (2018-02-28) Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.Hui Liu et al.Journal of leukocyte biology, 108(1), 253-266 (2020-04-10) Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.Pei-Feng Liu et al.Theranostics, 8(3), 830-845 (2018-01-19) Resveratrol ameliorates disorders of mitochondrial biogenesis and dynamics in a rat chronic ocular hypertension model.Xi Zhang et al.Life sciences, 207, 234-245 (2018-06-13) Pyoluteorin induces cell cycle arrest and apoptosis in human triple-negative breast cancer cells MDA-MB-231.Ting Ding et al.The Journal of pharmacy and pharmacology, 72(7), 969-978 (2020-04-05) Integrating virtual screening and biochemical experimental approach to identify potential anti-cancer agents from drug databank.Suman Jyoti Deka et al.Journal of bioinformatics and computational biology, 16(3), 1850002-1850002 (2018-03-24) Effects of Inhibin A on Apoptosis and Proliferation of Bovine Granulosa Cells.Huitao Xu et al.Animals : an open access journal from MDPI, 10(2) (2020-02-28) Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.Verónica Gómez-Pérez et al.European journal of medicinal chemistry, 89, 362-369 (2014-12-03) Development of apoptosis-inducing polypeptide via simultaneous mitochondrial membrane disruption and Ca2+ delivery.JongHoon Ha et al.Biomaterials, 197, 51-59 (2019-01-15) Runting and Stunting Syndrome Is Associated With Mitochondrial Dysfunction in Sex-Linked Dwarf Chicken.Hongmei Li et al.Frontiers in genetics, 10, 1337-1337 (2020-02-06) Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.Min Chul Kim et al.International journal of molecular medicine, 33(6), 1657-1663 (2014-03-22) Sulfated polysaccharide-protein complex sensitizes doxorubicin-induced apoptosis of breast cancer cells in vitro and in vivoJie Wang Experimental and Therapeutic Medicine (2016) iTRAQ-based proteomic analysis on the mitochondrial responses in gill tissues of juvenile olive flounder Paralichthys olivaceus exposed to cadmium.Zhen Lu et al.Environmental pollution (Barking, Essex : 1987), 257, 113591-113591 (2019-11-21) MiR-124-3p.1 Sensitizes Ovarian Cancer Cells to Mitochondrial Apoptosis Induced by Carboplatin.Xiaohong Deng et al.OncoTargets and therapy, 13, 5375-5386 (2020-07-02) Mitochondrial dysfunction and oxidative damage in the brain of diet-induced obese rats but not in diet-resistant rats.Weiwei Ma et al.Life sciences, 110(2), 53-60 (2014-07-25) Therapeutic hypothermia protects photoreceptors through activating Cirbp pathway.Ying-Jian Sun et al.Neurochemistry international, 126, 86-95 (2019-03-18) Antibiotic drug piperacillin induces neuron cell death through mitochondrial dysfunction and oxidative damage.Shan Jiang et al.Canadian journal of physiology and pharmacology, 96(6), 562-568 (2017-08-02) c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine.Pankaj Chaudhary et al.Biochemical pharmacology, 91(4), 457-473 (2014-09-03) The toxic mode of action of cyclic lipodepsipeptide fusaricidins, produced by Paenibacillus polymyxa, toward mammalian cells.R Mikkola et al.Journal of applied microbiology, 123(2), 436-449 (2017-05-31) Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity.Ritta Jubran et al.International journal of oncology, 57(4), 1013-1026 (2020-07-24) Enhancement of the Effect of Methyl Pyropheophorbide-a-Mediated Photodynamic Therapy was Achieved by Increasing ROS through Inhibition of Nrf2-HO-1 or Nrf2-ABCG2 Signaling.Si Tian et al.Anti-cancer agents in medicinal chemistry, 17(13), 1824-1836 (2017-03-31) Electroacupuncture pretreatment alleviates myocardial injury through regulating mitochondrial function.Chunai Wang et al.European journal of medical research, 25(1), 29-29 (2020-08-03) Mitochondrial transplantation attenuates lipopolysaccharide- induced depression-like behaviors.Yun Wang et al.Progress in neuro-psychopharmacology & biological psychiatry, 93, 240-249 (2019-04-26) Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice.Hongli Ma et al.Clinical science (London, England : 1979), 134(16), 2161-2175 (2020-08-15) Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.Yu Wang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41(6), 2432-2446 (2017-05-04) hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury.Yongmin Yan et al.Molecular therapy : the journal of the American Society of Gene Therapy, 25(2), 465-479 (2017-01-17) Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2.Jie Yu et al.International journal of molecular sciences, 19(6) (2018-06-21) High glucose condition induces autophagy in endothelial progenitor cells contributing to angiogenic impairment.Kyeong-A Kim et al.Biological & pharmaceutical bulletin, 37(7), 1248-1252 (2014-07-06) Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects.Yanqiu Han et al.International journal of biological macromolecules, 131, 769-778 (2019-03-18) Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer.Man Hu et al.Aging, 12(1), 138-155 (2020-01-07) Acanthopanax senticosus Protects Structure and Function of Mesencephalic Mitochondria in A Mouse Model of Parkinson's Disease.Shu-Min Liu et al.Chinese journal of integrative medicine, 24(11), 835-843 (2018-08-10) Protective Effects of Salidroside against Carbon Tetrachloride (CCl4)-Induced Liver Injury by Initiating Mitochondria to Resist Oxidative Stress in Mice.Shi-Yu Lin et al.International journal of molecular sciences, 20(13) (2019-07-03) CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.Juan Liu et al.Immunity, 50(3), 600-615 (2019-03-03) Major urinary protein 1 interacts with cannabinoid receptor type 1 in fatty acid-induced hepatic insulin resistance in a mouse hepatocyte model.Chin-Chang Chen et al.Biochemical and biophysical research communications, 460(4), 1063-1068 (2015-04-07) AdipoRon Protects Against Secondary Brain Injury After Intracerebral Hemorrhage via Alleviating Mitochondrial Dysfunction: Possible Involvement of AdipoR1-AMPK-PGC1α Pathway.Jun Yu et al.Neurochemical research, 44(7), 1678-1689 (2019-04-15) Salvianolic acid B inhibits intermittent high glucose-induced INS-1 cell apoptosis through regulation of Bcl-2 proteins and mitochondrial membrane potential.Shanjun Tao et al.European journal of pharmacology, 814, 56-62 (2017-08-13) Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence.Yue-Hua Jiang et al.Frontiers in pharmacology, 11, 512-512 (2020-05-16) Desipramine induces apoptosis in hepatocellular carcinoma cells.Dong Kwon Yang et al.Oncology reports, 38(2), 1029-1034 (2017-06-20) Herbometallic nano-drug inducing metastatic growth inhibition in breast cancer through intracellular energy depletion.Bhuban Ruidas et al.Molecular biology reports, 47(5), 3745-3763 (2020-05-04) Demethoxycurcumin in combination with ultraviolet radiation B induces apoptosis through the mitochondrial pathway and caspase activation in A431 and HaCaT cells.Yong Xin et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39(6), 1010428317706216-1010428317706216 (2017-06-18) Dibenzoxanthenes induce apoptosis and autophagy in HeLa cells by modeling the PI3K/Akt pathway.Xiu-Zhen Wang et al.Journal of photochemistry and photobiology. B, Biology, 187, 76-88 (2018-08-14) The peptide encoded by a novel putative lncRNA HBVPTPAP inducing the apoptosis of hepatocellular carcinoma cells by modulating JAK/STAT signaling pathways.Yong-Zhi Lun et al.Virus research, 287, 198104-198104 (2020-08-07) CGA ameliorates cognitive decline by regulating the PI3K/AKT signaling pathway and neurotransmitter systems in rats with multi-infarct dementia.Ying Fu et al.Experimental and therapeutic medicine, 20(5), 70-70 (2020-09-24) Qiliqiangxin attenuates hypoxia-induced injury in primary rat cardiac microvascular endothelial cells via promoting HIF-1α-dependent glycolysis.Yanyan Wang et al.Journal of cellular and molecular medicine, 22(5), 2791-2803 (2018-03-05) Intranasal delivery of paeoniflorin nanocrystals for brain targeting.Chaoyin Wu et al.Asian journal of pharmaceutical sciences, 15(3), 326-335 (2020-07-09) COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.Yiting Jia et al.Cell death & disease, 9(6), 676-676 (2018-06-06) Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast.Cory H T Boone et al.Redox biology, 12, 139-149 (2017-02-27) Chrysin induces death of prostate cancer cells by inducing ROS and ER stress.Soomin Ryu et al.Journal of cellular physiology, 232(12), 3786-3797 (2017-02-19) Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.Jiro Ogura et al.Biochemical pharmacology, 97(1), 89-98 (2015-06-30) H9 induces apoptosis via the intrinsic pathway in non-small-cell lung cancer A549 cells.Sae-Bom Kwon et al.Journal of microbiology and biotechnology, 25(3), 343-352 (2015-01-08) Structure and Anti-Tumor Activities of Exopolysaccharides from Alternaria mali Roberts.Pingchuan Yuan et al.Molecules (Basel, Switzerland), 24(7) (2019-04-10) Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells.Zhanpeng Yan et al.BMC complementary and alternative medicine, 19(1), 151-151 (2019-06-28) NAMPT maintains mitochondria content via NRF2-PPARα/AMPKα pathway to promote cell survival under oxidative stress.An Yu et al.Cellular signalling, 66, 109496-109496 (2019-12-10) Targeting hepatocellular carcinoma with piperine by radical-mediated mitochondrial pathway of apoptosis: An in vitro and in vivo study.Vetrichelvi Gunasekaran et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 105, 106-118 (2017-03-28) Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway.Hai Lan et al.Molecular medicine reports, 16(5), 7796-7804 (2017-09-26) Itraconazole exerts anti-liver cancer potential through the Wnt, PI3K/AKT/mTOR, and ROS pathways.Wenping Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 131, 110661-110661 (2020-09-18) Combined toxicity of prevalent mycotoxins studied in fish cell line and zebrafish larvae revealed that type of interactions is dose-dependent.Hongyuan Zhou et al.Aquatic toxicology (Amsterdam, Netherlands), 193, 60-71 (2017-10-19) Apoptotic-like changes in epididymal spermatozoa of soft-shelled turtles, Pelodiscus sinensis, during long-term storage at 4 ºC.Hong Chen et al.Animal reproduction science, 205, 134-143 (2019-05-08) The augmentation of O-GlcNAcylation reduces glyoxal-induced cell injury by attenuating oxidative stress in human retinal microvascular endothelial cells.Guo Dong Liu et al.International journal of molecular medicine, 36(4), 1019-1027 (2015-08-28) Calenduloside E Ameliorates Myocardial Ischemia-Reperfusion Injury through Regulation of AMPK and Mitochondrial OPA1.Min Wang et al.Oxidative medicine and cellular longevity, 2020, 2415269-2415269 (2020-09-17) Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson's disease model.Mi Jin Kim et al.Biomaterials, 64, 45-56 (2015-06-29) Oxidative stress mediates heat-induced changes of tight junction proteins in porcine sertoli cells via inhibiting CaMKKβ-AMPK pathway.Wei-Rong Yang et al.Theriogenology, 142, 104-113 (2019-10-07) Maresin 1 attenuates mitochondrial dysfunction through the ALX/cAMP/ROS pathway in the cecal ligation and puncture mouse model and sepsis patients.Jiaqi Gu et al.Laboratory investigation; a journal of technical methods and pathology, 98(6), 715-733 (2018-02-23) Reducing-Autophagy Derived Mitochondrial Dysfunction during Resveratrol Promotes Fibroblast-Like Synovial Cell Apoptosis.Wei Cao et al.Anatomical record (Hoboken, N.J. : 2007), 301(7), 1179-1188 (2018-02-21) Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression.Peng Shen et al.Cell death & disease, 11(5), 362-362 (2020-05-15) Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells.Guang Yang et al.Chemico-biological interactions, 288, 24-31 (2018-04-01) Sirtuin 3 Inhibits Airway Epithelial Mitochondrial Oxidative Stress in Cigarette Smoke-Induced COPD.Ming Zhang et al.Oxidative medicine and cellular longevity, 2020, 7582980-7582980 (2020-10-03) Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury.Yuan Liu et al.Journal of hepatology, 71(4), 719-730 (2019-06-16) (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one inhibited osteosarcoma growth by inducing apoptosis.Ming-Zhu Song et al.Experimental and therapeutic medicine, 18(2), 1107-1114 (2019-07-19) Role of mitochondrial dysfunction in renal fibrosis promoted by hypochlorite-modified albumin in a remnant kidney model and protective effects of antioxidant peptide SS-31.Hao Zhao et al.European journal of pharmacology, 804, 57-67 (2017-03-23) Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.S T Smiley et al.Proceedings of the National Academy of Sciences of the United States of America, 88(9), 3671-3675 (1991-05-01) Glycine-nitronyl nitroxide conjugate protects human umbilical vein endothelial cells against hypoxia/reoxygenation injury via multiple mechanisms and ameliorates hind limb ischemia/reperfusion injury in rats.Xiang Gao et al.Biochemical and biophysical research communications, 488(1), 239-246 (2017-05-14) Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway.Xin An et al.Nutrients, 12(5) (2020-05-28) Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives-Biological Activity Towards Cancer Cells.Jakub Iwanejko et al.Materials (Basel, Switzerland), 13(10) (2020-05-28) Oleanolic acid induces osteosarcoma cell apoptosis by inhibition of Notch signaling.Ying Xu et al.Molecular carcinogenesis, 57(7), 896-902 (2018-03-23) Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade.Lohanathan Bharathi Priya et al.Scientific reports, 7(1), 12283-12283 (2017-09-28) Zinc depletion promotes apoptosis-like death in drug-sensitive and antimony-resistance Leishmania donovani.Shalini Saini et al.Scientific reports, 7(1), 10488-10488 (2017-09-07) Schisandrin A prevents oxidative stress-induced DNA damage and apoptosis by attenuating ROS generation in C2C12 cells.Yung Hyun Choi Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 106, 902-909 (2018-08-19) The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.Zhiguo Li et al.Free radical biology & medicine, 130, 576-591 (2018-11-21) PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer.Shailender S Chauhan et al.Oncogene, 39(12), 2597-2611 (2020-01-30) Protection of Porcine Intestinal-Epithelial Cells from Deoxynivalenol-Induced Damage by Resveratrol via the Nrf2 Signaling Pathway.Jun Yang et al.Journal of agricultural and food chemistry, 67(6), 1726-1735 (2018-11-20) Neuroprotective role of hyperforin on aluminum maltolate-induced oxidative damage and apoptosis in PC12 cells and SH-SY5Y cells.Haoran Wang et al.Chemico-biological interactions, 299, 15-26 (2018-11-28) PKR Promotes Oxidative Stress and Apoptosis of Human Articular Chondrocytes by Causing Mitochondrial Dysfunction through p38 MAPK Activation-PKR Activation Causes Apoptosis in Human Chondrocytes.Ching-Hou Ma et al.Antioxidants (Basel, Switzerland), 8(9) (2019-09-06) Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells.Weilin Wang et al.Cancer letters, 358(1), 47-58 (2014-12-30) Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells.Yao Lu et al.International journal of molecular medicine, 36(5), 1223-1232 (2015-09-24) Antioxidative and cytoprotective response elicited by molybdenum nanoparticles in human cells.Mohd Javed Akhtar et al.Journal of colloid and interface science, 457, 370-377 (2015-07-22) Superparamagnetic iron oxide nanoparticles exacerbate the risks of reactive oxygen species-mediated external stresses.Cheng Luo et al.Archives of toxicology, 89(3), 357-369 (2014-05-23) Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.Gil Mendes Viana et al.Chemical & pharmaceutical bulletin, 65(10), 911-919 (2017-10-03) Comparison between electroporation and polyfection in pig sperm: efficiency and cell viability implications.Zigomar da Silva et al.Zygote (Cambridge, England), 26(4), 286-293 (2018-09-14) A comparison of radiation-induced mitochondrial damage between neural progenitor stem cells and differentiated cells.Tsutomu Shimura et al.Cell cycle (Georgetown, Tex.), 16(6), 565-573 (2017-01-25) Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis.Songfeng Chen et al.Apoptosis : an international journal on programmed cell death, 23(5-6), 299-313 (2018-05-01) PDGF-AA-induced filamentous mitochondria benefit dermal papilla cells in cellular migration.C Mifude et al.International journal of cosmetic science, 37(3), 266-271 (2014-12-09) The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells.Agnieszka Gornowicz et al.International journal of molecular sciences, 21(15) (2020-07-29) Mitigating effect of paxilline against injury produced by Cd2+ in rat pheochromocytoma PC12 and ascites hepatoma AS-30D cells.Elena A Belyaeva et al.Ecotoxicology and environmental safety, 196, 110519-110519 (2020-04-04) HOE-642 improves the protection of hypothermia on neuronal mitochondria after cardiac arrest in rats.Lanying Wei et al.American journal of translational research, 12(5), 2181-2191 (2020-06-09) Mechanisms of the immune response cause by cationic and anionic surface functionalized cellulose nanocrystals using cell-based assays.Hannah W Despres et al.Toxicology in vitro : an international journal published in association with BIBRA, 55, 124-133 (2018-12-24) WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner.K Brown et al.Oncogene, 36(22), 3119-3136 (2017-01-17) Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.Zhijun Guo et al.Cell chemical biology, 24(10), 1259-1275 (2017-09-19) A Tailored Multifunctional Anticancer Nanodelivery System for Ruthenium-Based Photosensitizers: Tumor Microenvironment Adaption and Remodeling.Jin-Hao Liang et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(1), 1901992-1901992 (2020-01-11) Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma.Sze-Kwan Lam et al.International journal of oncology, 46(1), 113-122 (2014-10-22) Female reproductive aging is master-planned at the level of ovary.Sayani Banerjee et al.PloS one, 9(5), e96210-e96210 (2014-05-03) O-GlcNAc Signaling Augmentation Protects Human Corneal Endothelial Cells from Oxidative Stress via AKT Pathway Activation.Chang Ki Yoon et al.Current eye research, 45(5), 556-562 (2020-01-11) Silencing of circFoxO3 Protects HT22 Cells from Glutamate-Induced Oxidative Injury via Regulating the Mitochondrial Apoptosis Pathway.Shao-Peng Lin et al.Cellular and molecular neurobiology, 40(7), 1231-1242 (2020-03-07) ZhiShiXiaoPi tang inhibits autophagy induced by corticosterone and functional dyspepsia through blockade of the mTOR pathway.Song Gao et al.Journal of ethnopharmacology, 238, 111836-111836 (2019-03-30) Regulation of Signaling Pathways Involved in the Anti-proliferative and Apoptosis-inducing Effects of M22 against Non-small Cell Lung Adenocarcinoma A549 Cells.Yao Yuan et al.Scientific reports, 8(1), 992-992 (2018-01-19) Protective effect of ethyl vanillin against Aβ-induced neurotoxicity in PC12 cells via the reduction of oxidative stress and apoptosis.Lei Zhong et al.Experimental and therapeutic medicine, 17(4), 2666-2674 (2019-04-02) Caspase-Independent Pathway is Related to Nilotinib Cytotoxicity in Cultured Cardiomyocytes.Qinghui Yang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(6), 2182-2193 (2017-08-17) Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency.Fiorella Colasuonno et al.Oxidative medicine and cellular longevity, 2020, 6821247-6821247 (2020-08-29) Restoration of GLP-1 secretion by Berberine is associated with protection of colon enterocytes from mitochondrial overheating in diet-induced obese mice.Yongning Sun et al.Nutrition & diabetes, 8(1), 53-53 (2018-09-27) A novel ferulic acid derivative attenuates myocardial cell hypoxia reoxygenation injury through a succinate dehydrogenase dependent antioxidant mechanism.Fei Wang et al.European journal of pharmacology, 856, 172417-172417 (2019-05-28) Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells.Zhifei Shao et al.Translational research : the journal of laboratory and clinical medicine, 166(1), 89-102 (2015-01-15) Zinc and calcium modulate mitochondrial redox state and morphofunctional integrity.Mahmoud S Sharaf et al.Free radical biology & medicine, 84, 142-153 (2015-04-07) Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells.Jinjing Wu et al.Drug design, development and therapy, 14, 2047-2060 (2020-06-18) Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade.Manuel Canedo-Antelo et al.Frontiers in molecular neuroscience, 11, 333-333 (2018-10-03) Tethering Interleukin-22 to Apolipoprotein A-I Ameliorates Mice from Acetaminophen-induced Liver Injury.Wei Chen et al.Theranostics, 7(17), 4135-4148 (2017-11-22) Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission.Jin Wang et al.Redox biology, 30, 101415-101415 (2020-01-07) Inhibition of miR-23a attenuates doxorubicin-induced mitochondria-dependent cardiomyocyte apoptosis by targeting the PGC-1α/Drp1 pathway.Jingjing Du et al.Toxicology and applied pharmacology, 369, 73-81 (2019-03-05) Toxicarioside N induces apoptosis in human gastric cancer SGC-7901 cell by activating the p38MAPK pathway.Huan-Ge Zhao et al.Archives of pharmacal research, 41(1), 71-78 (2017-09-25) Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA.Anastassia Serguienko et al.Oncotarget, 6(4), 2451-2465 (2015-02-12) Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.Wen Sun et al.Free radical biology & medicine, 108, 433-444 (2017-04-18) Overexpression of miR‑30c‑5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5.Xin Wang et al.International journal of molecular medicine, 45(2), 375-384 (2020-01-03) Myocardial ischemia/reperfusion upregulates the transcription of the Neuregulin1 receptor ErbB3, but only postconditioning preserves protein translation: Role in oxidative stress.Michela Morano et al.International journal of cardiology, 233, 73-79 (2017-02-07) Novel Homo-Bivalent and Polyvalent Compounds Based on Ligustrazine and Heterocyclic Ring as Anticancer Agents.Jiawen Wang et al.Molecules (Basel, Switzerland), 24(24) (2019-12-15) Therapeutic effects of melatonin on cerebral ischemia reperfusion injury: Role of Yap-OPA1 signaling pathway and mitochondrial fusion.Na Wei et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 110, 203-212 (2018-11-27) Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes.Guoyuan Qi et al.Biochimica et biophysica acta, 1863(6), 549-562 (2018-03-05) AMPK mediates the neurotoxicity of iron oxide nanoparticles retained in mitochondria or lysosomes.Hui Huang et al.Metallomics : integrated biometal science, 11(7), 1200-1206 (2019-06-27) Miconazole triggers various forms of cell death in human breast cancer MDA-MB-231 cells.W U Chengzhu et al.Die Pharmazie, 74(5), 290-294 (2019-05-22) Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.Sung-Kyun Ko et al.Nature chemistry, 6(10), 885-892 (2014-09-23) Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells.Yisen Cheng et al.Toxicology letters, 292, 136-150 (2018-05-04) β-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway.Daoju Gan et al.Oncology letters, 19(1), 291-300 (2020-01-04) Knockout serum replacement is an efficient serum substitute for cryopreservation of human spermatozoa.Seyed Mohamad Javad Taher-Mofrad et al.Cryobiology, 92, 208-214 (2020-02-01) Schizandra chinensis extracts induce apoptosis in human gastric cancer cells via JNK/p38 MAPK activation and the ROS-mediated/mitochondria-dependent pathway.Hyun Sul Kim et al.Pharmaceutical biology, 53(2), 212-219 (2014-09-23) Combined cell death of co-exposure to aldehyde mixtures on human bronchial epithelial BEAS-2B cells: Molecular insights into the joint action.Sen Zhang et al.Chemosphere, 244, 125482-125482 (2019-12-10) NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.Carolina Hassibe Thomé et al.Scientific reports, 10(1), 10315-10315 (2020-06-27) Osteochondritis Dissecans (OCD)-Derived Chondrocytes Display Increased Senescence, Oxidative Stress, Chaperone-Mediated Autophagy and, in Co-Culture with Adipose-Derived Stem Cells (ASCs), Enhanced Expression of MMP-13.Katarzyna Kornicka et al.Journal of clinical medicine, 8(3) (2019-03-13) Qian Li et al.Infectious diseases (London, England), 51(11-12), 793-801 (2019-08-15)Background:Porphyromonas gingivalis, a major pathogen of chronic periodontitis, adheres to and invades epithelial cells via an interaction between fimbriae and integrin. P. gingivalis proliferation and infection may affect the survival of cells. In this study, we further examined alternative signaling... Lycopene alleviates AFB1-induced immunosuppression by inhibiting oxidative stress and apoptosis in the spleen of mice.Feibo Xu et al.Food & function, 10(7), 3868-3879 (2019-06-12) The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748.Barbara Borowa-Mazgaj et al.Biochemical pharmacology, 142, 21-38 (2017-06-25) MTERF4 regulates the mitochondrial dysfunction induced by MPP(+) in SH-SY5Y cells.Xiaofei Ye et al.Biochemical and biophysical research communications, 464(1), 214-220 (2015-06-24) Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.Babak Baban et al.PloS one, 10(4), e0124059-e0124059 (2015-04-23) Quercetin supplemented casein-based extender improves the post-thaw quality of rooster semen.Michael Osei Appiah et al.Cryobiology, 94, 57-65 (2020-05-22) [D-Ala2, D-Leu5] Enkephalin Improves Liver Preservation During Normothermic Ex Vivo Perfusion.Eliza W Beal et al.The Journal of surgical research, 241, 323-335 (2019-05-10) Radiation induces apoptosis primarily through the intrinsic pathway in mammalian cells.Xianbin Cao et al.Cellular signalling, 62, 109337-109337 (2019-06-08) The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability.Shinji Ohkubo et al.International journal of oncology, 53(3), 1257-1268 (2018-06-30) 20-Hydroxyeicosatetraenoic Acid Is a Key Mediator of Angiotensin II-induced Apoptosis in Cardiac Myocytes.Huiying Zhao et al.Journal of cardiovascular pharmacology, 66(1), 86-95 (2015-07-15) Light-activatable Chlorin e6 (Ce6)-imbedded erythrocyte membrane vesicles camouflaged Prussian blue nanoparticles for synergistic photothermal and photodynamic therapies of cancer.Lihong Sun et al.Biomaterials science, 6(11), 2881-2895 (2018-09-08) Apoptosis signal-regulating kinase 1 promotes Ochratoxin A-induced renal cytotoxicity.Rui Liang et al.Scientific reports, 5, 8078-8078 (2015-01-30) Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway.Pei Zhang et al.Gene, 745, 144623-144623 (2020-03-31) Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells.Neha Kaushik et al.Scientific reports, 5, 8726-8726 (2015-03-05) The water extract of Liuwei dihuang possesses multi-protective properties on neurons and muscle tissue against deficiency of survival motor neuron protein.Yu-Ting Tseng et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 34, 97-105 (2017-09-14) The protective effects of moscatilin against methylglyoxal-induced neurotoxicity via the regulation of p38/JNK MAPK pathways in PC12 neuron-like cells.Mei Chou Lai et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 140, 111369-111369 (2020-04-24) Drug-free macromolecular therapeutics exhibit amplified apoptosis in G2/M phase arrested cells.Lian Li et al.Journal of drug targeting, 27(5-6), 566-572 (2018-09-11) Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke.Kai-Di Ren et al.European journal of pharmacology, 861, 172617-172617 (2019-08-21) Skin-derived precursor Schwann cells protect SH-SY5Y cells against 6-OHDA-induced neurotoxicity by PI3K/AKT/Bcl-2 pathway.Ying Chen et al.Brain research bulletin, 161, 84-93 (2020-05-04) Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth.Maria Eugenia Sabatino et al.Free radical biology & medicine, 120, 41-55 (2018-03-20) Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.Xiao-Man Liu et al.Endocrinology, 158(11), 3988-3999 (2017-09-25) Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.Chengzhi Xie et al.Molecular oncology, 9(2), 409-421 (2014-10-14) Composite ammonium glycyrrhizin has hepatoprotective effects in chicken hepatocytes with lipopolysaccharide/enrofloxacin-induced injury.Xuewen Guo et al.Experimental and therapeutic medicine, 20(5), 52-52 (2020-09-22) Mitofusin-2 mediated mitochondrial CaRuo-Peng Liang et al.World journal of gastroenterology, 23(38), 6995-7008 (2017-11-04) Preclinical evaluation of a regimen combining chidamide and ABT-199 in acute myeloid leukemia.Kai Chen et al.Cell death & disease, 11(9), 778-778 (2020-09-20) Stomatin-like protein 2 inhibits cisplatin-induced apoptosis through MEK/ERK signaling and the mitochondrial apoptosis pathway in cervical cancer cells.Guolin Hu et al.Cancer science, 109(5), 1357-1368 (2018-03-09) PERK/eIF-2α/CHOP Pathway Dependent ROS Generation Mediates Butein-induced Non-small-cell Lung Cancer Apoptosis and G2/M Phase Arrest.Shouyin Di et al.International journal of biological sciences, 15(8), 1637-1653 (2019-07-31) Specific cyprinid HIF isoforms contribute to cellular mitochondrial regulation.Jing Chen et al.Scientific reports, 10(1), 17246-17246 (2020-10-16) P38 MAP kinase is involved in oleuropein-induced apoptosis in A549 cells by a mitochondrial apoptotic cascade.Shasha Cao et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1425-1435 (2017-09-28) Effect of apigenin isolated from Aster yomena against Candida albicans: apigenin-triggered apoptotic pathway regulated by mitochondrial calcium signaling.Wonjong Lee et al.Journal of ethnopharmacology, 231, 19-28 (2018-11-09) Smokeless tobacco induces toxicity and apoptosis in neuronal cells: a mechanistic evaluation.Sushobhan Biswas et al.Free radical research, 54(7), 477-496 (2020-08-28) Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line.Alak Manna et al.Anti-cancer agents in medicinal chemistry, 15(9), 1156-1163 (2015-06-03) HSP90 maintains boar spermatozoa motility and mitochondrial membrane potential during heat stress.V Calle-Guisado et al.Animal reproduction science, 187, 13-19 (2017-10-17) Semen quality and fertilization ability of myostatin-knockout boars.Sheng-Zhong Han et al.Theriogenology, 135, 109-114 (2019-06-18) Robustaflavone induces G0/G1 cell cycle arrest and apoptosis in human umbilical vein endothelial cells and exhibits anti-angiogenic effects in vivo.Woo Kyung Sim et al.Scientific reports, 10(1), 11070-11070 (2020-07-08) Silymarin and its active component silibinin act as novel therapeutic alternatives for salivary gland cancer by targeting the ERK1/2-Bim signaling cascade.Eun-Sun Choi et al.Cellular oncology (Dordrecht), 40(3), 235-246 (2017-04-13) LncRNA WEE2-AS1 promotes proliferation and inhibits apoptosis in triple negative breast cancer cells via regulating miR-32-5p/TOB1 axis.Rong Wang et al.Biochemical and biophysical research communications, 526(4), 1005-1012 (2020-04-21) Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways.Ian T Saunders et al.Cancer cell international, 19, 98-98 (2019-04-24) Identification of N-Hydroxycinnamamide analogues and their bio-evaluation against breast cancer cell lines.Akhilesh Kumar Shukla et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 107, 475-483 (2018-08-15) Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice.Ting-Ting Zhou et al.Acta pharmacologica Sinica, 40(9), 1193-1204 (2019-03-06) Zinc enhances chemosensitivity to paclitaxel in PC‑3 prostate cancer cells.Ping Zhang et al.Oncology reports, 40(4), 2269-2277 (2018-08-15) A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma.Gabriela C Segat et al.Investigational new drugs, 38(4), 977-989 (2019-09-08) Tranexamic acid toxicity in human periarticular tissues.M McLean et al.Bone & joint research, 8(1), 11-18 (2019-02-26) Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma.Yang Gao et al.Theranostics, 9(5), 1264-1279 (2019-03-15) Dual mTOR/PI3K inhibitor NVP‑BEZ235 arrests colorectal cancer cell growth and displays differential inhibition of 4E‑BP1.Naif Alqurashi et al.Oncology reports, 40(2), 1083-1092 (2018-05-31) A Novel Isoquinoline Derivative Anticancer Agent and Its Targeted Delivery to Tumor Cells Using Transferrin-Conjugated Liposomes.Xuewei Yang et al.PloS one, 10(8), e0136649-e0136649 (2015-08-27) 13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity Against Oral Cancer Cells Through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts.Yi-Chang Liu et al.Marine drugs, 18(8) (2020-07-29) ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.Qi-Qiang Guo et al.The EMBO journal, 39(10), e103111-e103111 (2020-03-19) Eucalrobusone C suppresses cell proliferation and induces ROS-dependent mitochondrial apoptosis via the p38 MAPK pathway in hepatocellular carcinoma cells.Kai-Li Jian et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 25, 71-82 (2017-02-14) Centaurea cyanus extracted 13-O-acetylsolstitialin A decrease Bax/Bcl-2 ratio and expression of cyclin D1/Cdk-4 to induce apoptosis and cell cycle arrest in MCF-7 and MDA-MB-231 breast cancer cell lines.Mohammad Keyvanloo Shahrestanaki et al.Journal of cellular biochemistry, 120(10), 18309-18319 (2019-06-05) Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.Wei Qian et al.Proceedings of the National Academy of Sciences of the United States of America, 116(37), 18435-18444 (2019-08-28) Peptide-Templated Gold Clusters as Enzyme-Like Catalyst Boost Intracellular Oxidative Pressure and Induce Tumor-Specific Cell Apoptosis.Ya Zhang et al.Nanomaterials (Basel, Switzerland), 8(12) (2018-12-14) Autoinflammation in addition to combined immunodeficiency: SLC29A3 gene defect.Deniz Çağdaş et al.Molecular immunology, 121, 28-37 (2020-03-11) Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs).Xin He et al.Cell and tissue research, 362(2), 379-388 (2015-06-19) Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway.Hyun Hwangbo et al.Biomolecules & therapeutics, 28(5), 443-455 (2020-08-29) Upregulation of Mitochondrial Transcription Factor A Promotes the Repairment of Renal Tubular Epithelial Cells in Sepsis by Inhibiting Reactive Oxygen Species-Mediated Toll-Like Receptor 4/p38MAPK Signaling.Xin-Gui Dai et al.Pathobiology : journal of immunopathology, molecular and cellular biology, 86(5-6), 263-273 (2019-08-21) Preincubation with a low-dose hydrogen peroxide enhances anti-oxidative stress ability of BMSCs.Lei Wang et al.Journal of orthopaedic surgery and research, 15(1), 392-392 (2020-09-11) Paeonol alleviates interleukin-1β-induced inflammatory responses in chondrocytes during osteoarthritis.Mingran Liu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 914-921 (2017-09-16) Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.Chuan Li et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 28, 10-18 (2017-05-10) Altered FoF1 ATP synthase and susceptibility to mitochondrial permeability transition pore during ischaemia and reperfusion in aging cardiomyocytes.Celia Fernandez-Sanz et al.Thrombosis and haemostasis, 113(3), 441-451 (2015-01-30) Synthetic Dibenzoxanthene Derivatives Induce Apoptosis Through Mitochondrial Pathway in Human Hepatocellular Cancer Cells.Zhi Jia et al.Applied biochemistry and biotechnology, 186(1), 145-160 (2018-03-13) Monocyte-derived multipotent cell delivered programmed therapeutics to reverse idiopathic pulmonary fibrosis.Xin Chang et al.Science advances, 6(22), eaba3167-eaba3167 (2020-06-11) Novel K6-K14 keratin fusion enhances cancer stemness and aggressiveness in oral squamous cell carcinoma.Fuu-Jen Tsai et al.Oncogene, 38(26), 5113-5126 (2019-03-15) Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.Tahir Mehmood et al.Journal of Cancer, 8(18), 3707-3717 (2017-11-21) DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.Qian Zhang et al.The Journal of experimental medicine, 211(13), 2549-2566 (2014-11-26) Gallic acid caused cultured mice TM4 Sertoli cells apoptosis and necrosis.Wanhong Li et al.Asian-Australasian journal of animal sciences, 32(5), 629-636 (2018-11-02) Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons.Kaihua Wang et al.International journal of molecular medicine, 40(5), 1582-1590 (2017-09-28) FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway.Lihua Cui et al.Life sciences, 217, 243-250 (2018-12-15) EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells.Ju-Hee Lee et al.Oncotarget, 6(12), 9701-9717 (2015-05-21) Sirt6 Suppresses High Glucose-Induced Mitochondrial Dysfunction and Apoptosis in Podocytes through AMPK Activation.Yanqin Fan et al.International journal of biological sciences, 15(3), 701-713 (2019-02-13) Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression.Bin Zhang et al.Molecules (Basel, Switzerland), 24(2) (2019-01-13) Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells.Jin Seok et al.Stem cell research & therapy, 11(1), 1-1 (2020-01-05) Deoxynucleosides with benzimidazoles as aglycone moiety are potent anticancer agents.Mirosława Koronkiewicz et al.European journal of pharmacology, 820, 146-155 (2017-12-17) Perfluoro-octanoic acid impairs sperm motility through the alteration of plasma membrane.I Šabović et al.Journal of endocrinological investigation, 43(5), 641-652 (2019-11-30) Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death.Hyun Kyung Park et al.International journal of molecular sciences, 21(7) (2020-04-16) Artesunate induces apoptosis through caspase-dependent and -independent mitochondrial pathways in human myelodysplastic syndrome SKM-1 cells.Ying Wang et al.Chemico-biological interactions, 219, 28-36 (2014-04-08) Short-term exposure to ZnO/MCB persistent free radical particles causes mouse lung lesions via inflammatory reactions and apoptosis pathways.Xing Zhang et al.Environmental pollution (Barking, Essex : 1987), 261, 114039-114039 (2020-03-30) Urban particulate matter disturbs the equilibrium of mitochondrial dynamics and biogenesis in human vascular endothelial cells.Yan Wang et al.Environmental pollution (Barking, Essex : 1987), 264, 114639-114639 (2020-05-11) 2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1).Jie Yu et al.Free radical biology & medicine, 152, 336-347 (2020-04-03) The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis.Jiankai Zhong et al.Aging, 12(13), 13618-13632 (2020-07-10) Sonodynamic therapy in atherosclerosis by curcumin nanosuspensions: Preparation design, efficacy evaluation, and mechanisms analysis.Lei Jiang et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 101-110 (2019-12-17) Escin induces apoptosis in human bladder cancer cells: An in vitro and in vivo study.Chen-Li Cheng et al.European journal of pharmacology, 840, 79-88 (2018-10-06) Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.Jian-guo Sun et al.Cancer letters, 355(2), 253-263 (2014-10-12) Deoxyelephantopin induces apoptosis via oxidative stress and enhances gemcitabine sensitivity in vitro and in vivo through targeting the NF-κB signaling pathway in pancreatic cancer.Daolin Ji et al.Aging, 12(11), 11116-11138 (2020-06-12) Ferulic acid renders protection to HEK293 cells against oxidative damage and apoptosis induced by hydrogen peroxide.Yuan-Yuan Bian et al.In vitro cellular & developmental biology. Animal, 51(7), 722-729 (2015-02-14) Housefly Pupae-Derived Antioxidant Peptides Exerting Neuroprotective Effects on Hydrogen Peroxide-Induced Oxidative Damage in PC12 Cells.Tingting Sun et al.Molecules (Basel, Switzerland), 24(24) (2019-12-11) Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells.Bo Ra You et al.Oncotarget, 8(11), 17726-17737 (2017-01-19) Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin.Min-Hua Wu et al.Oncotarget, 9(4), 4787-4797 (2018-02-13) Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity.Li-Na He et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(4), 361-372 (2015-03-31) Near-Infrared-Triggered Release of Ca2+ Ions for Potential Application in Combination Cancer Therapy.Qiaoshan Chen et al.Advanced healthcare materials, 8(6), e1801113-e1801113 (2018-11-06) Anti-leukemia activity of a Hsp70 inhibitor and its hybrid molecules.Seong-Hyun Park et al.Scientific reports, 7(1), 3537-3537 (2017-06-16) EGCG stimulates the recruitment of brite adipocytes, suppresses adipogenesis and counteracts TNF-α-triggered insulin resistance in adipocytes.Yashi Mi et al.Food & function, 9(6), 3374-3386 (2018-06-06) NOX1 down-regulation attenuated the autophagy and oxidative damage in pig intestinal epithelial cell following transcriptome analysis of transport stress.Huari Li et al.Gene, 763, 145071-145071 (2020-08-23) MicroRNA-34a promotes mitochondrial dysfunction-induced apoptosis in human lens epithelial cells by targeting Notch2.Fan Fan et al.Oncotarget, 8(66), 110209-110220 (2018-01-05) FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis.Di Wang et al.British journal of pharmacology, 177(2), 432-448 (2019-10-28) Lycopene induces apoptosis in Candida albicans through reactive oxygen species production and mitochondrial dysfunction.Hyemin Choi et al.Biochimie, 115, 108-115 (2015-05-26) Anandamide exerts a suppressive effect on sperm binding to oviduct explants through CB1 receptors in the water buffalo (Bubalus bubalis).Vimlesh Kumar et al.Animal reproduction science, 185, 188-194 (2017-09-05) Synergic prooxidant, apoptotic and TRPV1 channel activator effects of alpha-lipoic acid and cisplatin in MCF-7 breast cancer cells.Gökhan Nur et al.Journal of receptor and signal transduction research, 37(6), 569-577 (2017-08-30) Pharmacological modulation of autophagy to protect cardiomyocytes according to the time windows of ischaemia/reperfusion.Qiulin Xu et al.British journal of pharmacology, 172(12), 3072-3085 (2015-02-11) Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.Chengzhi Xie et al.Molecular oncology, 9(2), 409-421 (2014-10-14) Composite ammonium glycyrrhizin has hepatoprotective effects in chicken hepatocytes with lipopolysaccharide/enrofloxacin-induced injury.Xuewen Guo et al.Experimental and therapeutic medicine, 20(5), 52-52 (2020-09-22) PERK/eIF-2α/CHOP Pathway Dependent ROS Generation Mediates Butein-induced Non-small-cell Lung Cancer Apoptosis and G2/M Phase Arrest.Shouyin Di et al.International journal of biological sciences, 15(8), 1637-1653 (2019-07-31) Specific cyprinid HIF isoforms contribute to cellular mitochondrial regulation.Jing Chen et al.Scientific reports, 10(1), 17246-17246 (2020-10-16) P38 MAP kinase is involved in oleuropein-induced apoptosis in A549 cells by a mitochondrial apoptotic cascade.Shasha Cao et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1425-1435 (2017-09-28) Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling.Daniele Mercatelli et al.Frontiers in pharmacology, 11, 630-630 (2020-05-28) Synergistic Effect of Graphene Oxide Coated Nanotised Apigenin with Paclitaxel (GO-NA/PTX): A ROS Dependent Mitochondrial Mediated Apoptosis in Ovarian Cancer.Manish Kumar Pal et al.Anti-cancer agents in medicinal chemistry, 17(12), 1721-1732 (2017-04-27) Protective Effects of Nargenicin A1 against Tacrolimus-Induced Oxidative Stress in Hirame Natural Embryo Cells.Cheol Park et al.International journal of environmental research and public health, 16(6) (2019-03-27) Taurine attenuates isoproterenol-induced H9c2 cardiomyocytes hypertrophy by improving antioxidative ability and inhibiting calpain-1-mediated apoptosis.Weiwei Li et al.Molecular and cellular biochemistry, 469(1-2), 119-132 (2020-04-19) Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway.Jun-Shan Liu et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 61, 152843-152843 (2019-05-01) A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.Jingwen Xu et al.Steroids, 161, 108672-108672 (2020-06-03) Inverse opal substrate-loaded mesenchymal stem cells contribute to decreased myocardial remodeling after transplantation into acute myocardial infarction mice.Wenbin Lu et al.International journal of nanomedicine, 13, 7033-7046 (2018-11-23) Altered cellular metabolism of HepG2 cells caused by microcystin-LR.Junguo Ma et al.Environmental pollution (Barking, Essex : 1987), 225, 610-619 (2017-03-25) Nutrition deficiency promotes apoptosis of cartilage endplate stem cells in a caspase-independent manner partially through upregulating BNIP3.Zhiliang He et al.Acta biochimica et biophysica Sinica, 49(1), 25-32 (2016-11-20) Peroxiredoxin 6 Confers Protection Against Nonalcoholic Fatty Liver Disease Through Maintaining Mitochondrial Function.Dong Hun Lee et al.Antioxidants & redox signaling, 31(5), 387-402 (2019-04-23) Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy.Yu-Ting Tseng et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 53, 96-106 (2019-01-23) Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity.Leonel A Cortes et al.PloS one, 10(8), e0136852-e0136852 (2015-09-01) Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways.Jiumao Lin et al.BMC cancer, 14, 729-729 (2014-10-01) Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells.Yuefan Ma et al.Oncology reports, 39(6), 2899-2905 (2018-04-06) Targeting cyclophilin-D by compound 19 protects neuronal cells from oxygen glucose deprivation/re-oxygenation.Jinyu Zheng et al.Oncotarget, 8(52), 90238-90249 (2017-11-23) Lycopene Inhibits Reactive Oxygen Species-Mediated NF-κB Signaling and Induces Apoptosis in Pancreatic Cancer Cells.Yoonseon Jeong et al.Nutrients, 11(4) (2019-04-04) Skin-derived precursor Schwann cells protect SH-SY5Y cells against 6-OHDA-induced neurotoxicity by PI3K/AKT/Bcl-2 pathway.Ying Chen et al.Brain research bulletin, 161, 84-93 (2020-05-04) Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth.Maria Eugenia Sabatino et al.Free radical biology & medicine, 120, 41-55 (2018-03-20) Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.Xiao-Man Liu et al.Endocrinology, 158(11), 3988-3999 (2017-09-25) NGF protects bone marrow mesenchymal stem cells against 2,5-hexanedione-induced apoptosis in vitro via Akt/Bad signal pathway.Qi Wang et al.Molecular and cellular biochemistry, 457(1-2), 133-143 (2019-03-27) The marine toxin palytoxin induces necrotic death in HaCaT cells through a rapid mitochondrial damage.Marco Pelin et al.Toxicology letters, 229(3), 440-450 (2014-07-30) Leveraging growth factor induced macropinocytosis for targeted treatment of lung cancer.Raul Iglesias et al.Medical oncology (Northwood, London, England), 32(12), 259-259 (2015-11-01) Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways.Yunmin Lu et al.Pharmaceutical biology, 52(6), 789-795 (2014-05-16) Md Abdul Hannan et al.Antioxidants (Basel, Switzerland), 9(3) (2020-03-19)Oxidative stress is known to be critically implicated in the pathophysiology of several neurological disorders, including Alzheimer's disease and ischemic stroke. The remarkable neurotrophic activity of Gelidium amansii, which has been reported consistently in a series of our previous studies... Pharmacological profile of opicapone, a third-generation nitrocatechol catechol-O-methyl transferase inhibitor, in the rat.M J Bonifácio et al.British journal of pharmacology, 172(7), 1739-1752 (2014-11-21) Anti-tumor Properties of Picrasma quassioides Extracts in H-RasG12V Liver Cancer Are Mediated Through ROS-dependent Mitochondrial Dysfunction.Dan-Ping Xie et al.Anticancer research, 40(7), 3819-3830 (2020-07-06) Homocysteine induces oxidative stress to damage trabecular meshwork cells.Zhi-Peng You et al.Experimental and therapeutic medicine, 15(5), 4379-4385 (2018-05-05) The Effects of Cadmium at Low Environmental Concentrations on THP-1 Macrophage Apoptosis.Tomasz Olszowski et al.International journal of molecular sciences, 16(9), 21410-21427 (2015-09-16) The effect of two packaging systems on the post-thaw characteristics of canine sperm.R Strzeżek et al.Polish journal of veterinary sciences, 18(2), 249-253 (2015-07-15) A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse.Radovan Krejcir et al.International journal of molecular sciences, 20(17) (2019-08-31) Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways.Ruixue Xia et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(3), 987-998 (2017-07-01) Ganoderic acid A exerts antitumor activity against MDA-MB-231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway.Yuguang Yang et al.Oncology letters, 16(5), 6515-6521 (2018-11-09) Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-β/STAT3 Pathway.Zhenghuan Fang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(5), 1751-1768 (2018-06-29) Physakengose G induces apoptosis via EGFR/mTOR signaling and inhibits autophagic flux in human osteosarcoma cells.Hua Lin et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 42, 190-198 (2018-04-16) Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization.Yuta Kanamori et al.Experimental and therapeutic medicine, 19(2), 1511-1521 (2020-02-06) Cytoplasmic upregulation of Cyto c and AIF serve as biomarkers of mechanical asphyxia death.Heng Zhang et al.American journal of translational research, 11(7), 4568-4583 (2019-08-10) Comparison of changes in mitochondrial bioenergetics between keratinocytes in human external auditory canal skin and cholesteatomas from normoxia to hypoxia.Cheng-Ping Shih et al.Scientific reports, 8(1), 125-125 (2018-01-11) Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway.Dhiraj Kumar et al.BMC cancer, 18(1), 52-52 (2018-01-10) Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone triggers mitochondrial dysfunction and apoptosis in neutrophils through calcium signaling.Pradeep Kumar Singh et al.Medical microbiology and immunology, 208(6), 855-868 (2019-08-05) Cardiomyocytes cultured on mechanically compliant substrates, but not on conventional culture devices, exhibit prominent mitochondrial dysfunction due to reactive oxygen species and insulin resistance under high glucose.Masaki Morishima et al.PloS one, 13(8), e0201891-e0201891 (2018-08-24) Melatonin alleviates aluminium chloride-induced immunotoxicity by inhibiting oxidative stress and apoptosis associated with the activation of Nrf2 signaling pathway.Hongyan Yu et al.Ecotoxicology and environmental safety, 173, 131-141 (2019-02-17) Phytanic acid induces Neuro2a cell death via histone deacetylase activation and mitochondrial dysfunction.Kaoru Nagai Neurotoxicology and teratology, 48, 33-39 (2015-01-27) Nobiletin (NOB) suppresses autophagic degradation via over-expressing AKT pathway and enhances apoptosis in multidrug-resistant SKOV3/TAX ovarian cancer cells.Ya-Ping Jiang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 29-37 (2018-04-11) Mitofusin-2 mediated mitochondrial CaRuo-Peng Liang et al.World journal of gastroenterology, 23(38), 6995-7008 (2017-11-04) Preclinical evaluation of a regimen combining chidamide and ABT-199 in acute myeloid leukemia.Kai Chen et al.Cell death & disease, 11(9), 778-778 (2020-09-20) The peptide encoded by a novel putative lncRNA HBVPTPAP inducing the apoptosis of hepatocellular carcinoma cells by modulating JAK/STAT signaling pathways.Yong-Zhi Lun et al.Virus research, 287, 198104-198104 (2020-08-07) Mitigating effect of paxilline against injury produced by Cd2+ in rat pheochromocytoma PC12 and ascites hepatoma AS-30D cells.Elena A Belyaeva et al.Ecotoxicology and environmental safety, 196, 110519-110519 (2020-04-04) HOE-642 improves the protection of hypothermia on neuronal mitochondria after cardiac arrest in rats.Lanying Wei et al.American journal of translational research, 12(5), 2181-2191 (2020-06-09) Oxidative stress mediates heat-induced changes of tight junction proteins in porcine sertoli cells via inhibiting CaMKKβ-AMPK pathway.Wei-Rong Yang et al.Theriogenology, 142, 104-113 (2019-10-07) Maresin 1 attenuates mitochondrial dysfunction through the ALX/cAMP/ROS pathway in the cecal ligation and puncture mouse model and sepsis patients.Jiaqi Gu et al.Laboratory investigation; a journal of technical methods and pathology, 98(6), 715-733 (2018-02-23) Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.Yu Wang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41(6), 2432-2446 (2017-05-04) α-Mangostin reduced the viability of A594 cells in vitro by provoking ROS production through downregulation of NAMPT/NAD.Yan-Yun Ding et al.Cell stress & chaperones, 25(1), 163-172 (2020-01-04) A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.Anja Bastian et al.The Journal of pharmacology and experimental therapeutics, 353(2), 392-404 (2015-02-28) Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.Sudhir Pandey et al.American journal of physiology. Cell physiology, 317(2), C235-C243 (2019-05-23) Gadolinium Oxide Nanoparticles Induce Toxicity in Human Endothelial HUVECs via Lipid Peroxidation, Mitochondrial Dysfunction and Autophagy Modulation.Mohd Javed Akhtar et al.Nanomaterials (Basel, Switzerland), 10(9) (2020-08-30) Mechanisms of the immune response cause by cationic and anionic surface functionalized cellulose nanocrystals using cell-based assays.Hannah W Despres et al.Toxicology in vitro : an international journal published in association with BIBRA, 55, 124-133 (2018-12-24) WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner.K Brown et al.Oncogene, 36(22), 3119-3136 (2017-01-17) Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.Zhijun Guo et al.Cell chemical biology, 24(10), 1259-1275 (2017-09-19) A Tailored Multifunctional Anticancer Nanodelivery System for Ruthenium-Based Photosensitizers: Tumor Microenvironment Adaption and Remodeling.Jin-Hao Liang et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(1), 1901992-1901992 (2020-01-11) Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma.Sze-Kwan Lam et al.International journal of oncology, 46(1), 113-122 (2014-10-22) Female reproductive aging is master-planned at the level of ovary.Sayani Banerjee et al.PloS one, 9(5), e96210-e96210 (2014-05-03) O-GlcNAc Signaling Augmentation Protects Human Corneal Endothelial Cells from Oxidative Stress via AKT Pathway Activation.Chang Ki Yoon et al.Current eye research, 45(5), 556-562 (2020-01-11) Silencing of circFoxO3 Protects HT22 Cells from Glutamate-Induced Oxidative Injury via Regulating the Mitochondrial Apoptosis Pathway.Shao-Peng Lin et al.Cellular and molecular neurobiology, 40(7), 1231-1242 (2020-03-07) ZhiShiXiaoPi tang inhibits autophagy induced by corticosterone and functional dyspepsia through blockade of the mTOR pathway.Song Gao et al.Journal of ethnopharmacology, 238, 111836-111836 (2019-03-30) PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.Jiachao Guo et al.Aging, 12(4), 3976-3992 (2020-02-26) A combination of low-dose decitabine and chidamide resulted in synergistic effects on the proliferation and apoptosis of human myeloid leukemia cell lines.Fangfang Xu et al.American journal of translational research, 11(12), 7644-7655 (2020-01-15) Inhibition of GPR35 Preserves Mitochondrial Function After Myocardial Infarction by Targeting Calpain 1/2.Ken Chen et al.Journal of cardiovascular pharmacology, 75(6), 556-563 (2020-03-21) The selective target of capsaicin on FASN expression and de novo fatty acid synthesis mediated through ROS generation triggers apoptosis in HepG2 cells.Hathaichanok Impheng et al.PloS one, 9(9), e107842-e107842 (2014-09-26) Luteolin inhibits ROS-activated MAPK pathway in myocardial ischemia/reperfusion injury.Dongsheng Yu et al.Life sciences, 122, 15-25 (2014-12-06) High glucose condition induces autophagy in endothelial progenitor cells contributing to angiogenic impairment.Kyeong-A Kim et al.Biological & pharmaceutical bulletin, 37(7), 1248-1252 (2014-07-06) CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.Juan Liu et al.Immunity, 50(3), 600-615 (2019-03-03) Major urinary protein 1 interacts with cannabinoid receptor type 1 in fatty acid-induced hepatic insulin resistance in a mouse hepatocyte model.Chin-Chang Chen et al.Biochemical and biophysical research communications, 460(4), 1063-1068 (2015-04-07) AdipoRon Protects Against Secondary Brain Injury After Intracerebral Hemorrhage via Alleviating Mitochondrial Dysfunction: Possible Involvement of AdipoR1-AMPK-PGC1α Pathway.Jun Yu et al.Neurochemical research, 44(7), 1678-1689 (2019-04-15) Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury.Yuan Liu et al.Journal of hepatology, 71(4), 719-730 (2019-06-16) (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one inhibited osteosarcoma growth by inducing apoptosis.Ming-Zhu Song et al.Experimental and therapeutic medicine, 18(2), 1107-1114 (2019-07-19) Role of mitochondrial dysfunction in renal fibrosis promoted by hypochlorite-modified albumin in a remnant kidney model and protective effects of antioxidant peptide SS-31.Hao Zhao et al.European journal of pharmacology, 804, 57-67 (2017-03-23) Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1.Kuan-Chou Chen et al.International journal of molecular sciences, 21(9) (2020-05-15) Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.Eun Ji Joo et al.Chemico-biological interactions, 233, 25-34 (2015-04-01) Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells.Y Dong et al.European review for medical and pharmacological sciences, 23(3), 1047-1054 (2019-02-20) Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype.Hripsimé Nahapetyan et al.Cell death & disease, 10(2), 119-119 (2019-02-12) Quercetin improves the activity of the ubiquitin-proteasomal system in 150Q mutated huntingtin-expressing cells but exerts detrimental effects on neuronal survivability.J Chakraborty et al.Journal of neuroscience research, 93(10), 1581-1591 (2015-07-15) Bovine serum albumin and skim-milk improve boar sperm motility by enhancing energy metabolism and protein modifications during liquid storage at 17 °C.Jieli Fu et al.Theriogenology, 102, 87-97 (2017-08-02) Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells.Thomas Henzi et al.PloS one, 10(11), e0142005-e0142005 (2015-11-06) Mitogenic activity of Artocarpus lingnanensis lectin and its apoptosis induction in Jurkat T cells.Linjie Zeng et al.Journal of natural medicines, 72(3), 745-756 (2018-04-14) BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo.Longchuan Bai et al.PloS one, 9(6), e99404-e99404 (2014-06-06) α-Arbutin Protects Against Parkinson's Disease-Associated Mitochondrial Dysfunction In Vitro and In Vivo.Yaqi Ding et al.Neuromolecular medicine, 22(1), 56-67 (2019-08-12) Antibiotic drug piperacillin induces neuron cell death through mitochondrial dysfunction and oxidative damage.Shan Jiang et al.Canadian journal of physiology and pharmacology, 96(6), 562-568 (2017-08-02) c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine.Pankaj Chaudhary et al.Biochemical pharmacology, 91(4), 457-473 (2014-09-03) The toxic mode of action of cyclic lipodepsipeptide fusaricidins, produced by Paenibacillus polymyxa, toward mammalian cells.R Mikkola et al.Journal of applied microbiology, 123(2), 436-449 (2017-05-31) Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity.Ritta Jubran et al.International journal of oncology, 57(4), 1013-1026 (2020-07-24) A novel polysaccharide from the Sarcodon aspratus triggers apoptosis in Hela cells via induction of mitochondrial dysfunction.Dan-Dan Wang et al.Food & nutrition research, 62 (2018-03-17) A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.Jeong Eon Park et al.Biomolecules & therapeutics, 25(4), 404-410 (2017-05-31) Edaravone Attenuates the Proinflammatory Response in Amyloid-β-Treated Microglia by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion.Hong-Mei Wang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(3), 1113-1125 (2017-10-05) microRNA-579 upregulation mediates death of human macrophages with mycobacterium tuberculosis infection.Jun Ma et al.Biochemical and biophysical research communications, 518(2), 219-226 (2019-08-23) Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells.Jiyeon Ham et al.Journal of cellular physiology, 233(2), 1638-1649 (2017-06-29) Osthole resensitizes CD133+ hepatocellular carcinoma cells to cisplatin treatment via PTEN/AKT pathway.Junfeng Ye et al.Aging, 12(14), 14406-14417 (2020-07-17) SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.Dejun Xu et al.International journal of molecular sciences, 20(6) (2019-03-21) Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro.Yun-Yi Ma et al.Journal of ovarian research, 10(1), 47-47 (2017-07-22) Changshuang Fu et al.Oncology letters, 17(1), 303-313 (2019-01-19)Cistanche tubulosa has various biological functions. In the present study, the antitumor effect of water-soluble phenylethanoid glycosides of C. tubulosa (CTPG-W) on esophageal cancer was investigated. Eca-109 cells were treated with CTPG-W and the cell viability was measured by MTT... Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells.Jingchao Wu et al.Journal of neuro-oncology, 120(1), 33-41 (2014-07-23) Acetylcholinesterase overexpression mediated by oncolytic adenovirus exhibited potent anti-tumor effect.Haineng Xu et al.BMC cancer, 14, 668-668 (2014-09-16) Capsaicin inhibits proliferation and induces apoptosis in osteosarcoma cell lines via the mitogen‑activated protein kinase pathway.Yuan Zhang et al.Oncology reports, 38(5), 2685-2696 (2017-10-20) Tumour growth-suppressive effect of arsenic trioxide in squamous cell lung carcinoma.Leanne Lee Leung et al.Oncology letters, 14(3), 3748-3754 (2017-09-21) Human Osteoblast Cell Behaviour on Titanium Discs Treated with Argon Plasma.Carolina González-Blanco et al.Materials (Basel, Switzerland), 12(11) (2019-05-31) Cytotoxic and chemosensitization effects of Scutellarin from traditional Chinese herb Scutellaria altissima L. in human prostate cancer cells.Chen Gao et al.Oncology reports, 38(3), 1491-1499 (2017-07-25) Necrosulfonamide Ameliorates Neurological Impairment in Spinal Cord Injury by Improving Antioxidative Capacity.Jianhang Jiao et al.Frontiers in pharmacology, 10, 1538-1538 (2020-01-31) TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury.Zhiping Li et al.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 25(4), 595-600 (2017-06-06) A novel chalcone derivative S17 induces apoptosis through ROS dependent DR5 up-regulation in gastric cancer cells.Saiyang Zhang et al.Scientific reports, 7(1), 9873-9873 (2017-08-31) Obacunone attenuates high glucose-induced oxidative damage in NRK-52E cells by inhibiting the activity of GSK-3β.Jie Zhou et al.Biochemical and biophysical research communications, 513(1), 226-233 (2019-04-08) Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway.Zhiyun Cao et al.Molecular medicine reports, 12(2), 2800-2806 (2015-05-06) JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1.Jiong Yang et al.International journal of molecular sciences, 16(10), 25744-25758 (2015-10-31) TiO2 Nanotubes Alleviate Diabetes-Induced Osteogenetic Inhibition.Jinghong Yang et al.International journal of nanomedicine, 15, 3523-3537 (2020-06-18) Erianin protects against high glucose-induced oxidative injury in renal tubular epithelial cells.Mei-Fen Chen et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 126, 97-105 (2019-02-15) Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.Zhong Wang et al.Translational stroke research, 9(1), 74-91 (2017-08-03) Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.J Abdi et al.The Journal of nutritional biochemistry, 25(12), 1254-1262 (2014-10-04) Induction of autophagy, apoptosis and aquisition of resistance in response to piceatannol toxicity in MOLT-4 human leukemia cells.Kamila Siedlecka-Kroplewska et al.Toxicology in vitro : an international journal published in association with BIBRA, 59, 12-25 (2019-04-04) Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468.Maryam Hamzeloo-Moghadam et al.OncoTargets and therapy, 11, 7669-7677 (2018-11-23) lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.Xiaomin Su et al.Molecular therapy. Nucleic acids, 20, 841-850 (2020-05-29) Effect of the TYK-2/STAT-3 pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate.Wen Qi et al.Molecular and cellular endocrinology, 484, 52-58 (2019-01-21) Mitoquinone restores platelet production in irradiation-induced thrombocytopenia.Haley Ramsey et al.Platelets, 26(5), 459-466 (2014-07-16) Nickel and zinc complexes of testosterone N4-substituted thiosemicarbazone: Selective cytotoxicity towards human colorectal carcinoma cell line HCT 116 and their cell death mechanisms.Mok Piew Heng et al.Journal of inorganic biochemistry, 208, 111097-111097 (2020-05-22) Combination cancer treatment through photothermally controlled release of selenous acid from gold nanocages.Haoyan Cheng et al.Biomaterials, 178, 517-526 (2018-04-11) Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells.Swati Mandal et al.The Biochemical journal, 468(3), 435-447 (2015-04-08) Resveratrol alleviates inflammatory injury and enhances the apoptosis of fibroblast‑like synoviocytes via mitochondrial dysfunction and ER stress in rats with adjuvant arthritis.Jinsen Lu et al.Molecular medicine reports, 20(1), 463-472 (2019-06-11) Shikonin protects H9C2 cardiomyocytes against hypoxia/reoxygenation injury through activation of PI3K/Akt signaling pathway.Shuang Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 104, 712-717 (2018-05-29) Synthesis, characterization and in vitro and in vivo photodynamic activities of a gallium(iii) tris(ethoxycarbonyl)corrole.Zhao Zhang et al.Dalton transactions (Cambridge, England : 2003), 46(29), 9481-9490 (2017-07-14) Folate acid-Cyclodextrin/Docetaxel induces apoptosis in KB cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.Jin Tao et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 111, 540-548 (2017-11-04) Melatonin Enhances Palladium-Nanoparticle-Induced Cytotoxicity and Apoptosis in Human Lung Epithelial Adenocarcinoma Cells A549 and H1229.Sangiliyandi Gurunathan et al.Antioxidants (Basel, Switzerland), 9(4) (2020-04-30) Human Osteoblast Cell Behaviour on Titanium Discs Treated with Argon Plasma.Carolina González-Blanco et al.Materials (Basel, Switzerland), 12(11) (2019-05-31) Cytotoxic and chemosensitization effects of Scutellarin from traditional Chinese herb Scutellaria altissima L. in human prostate cancer cells.Chen Gao et al.Oncology reports, 38(3), 1491-1499 (2017-07-25) MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma.Lin Yang et al.Biochimica et biophysica acta. Molecular cell research, 1867(12), 118826-118826 (2020-08-19) Induction of Live Cell Phagocytosis by a Specific Combination of Inflammatory Stimuli.Takamasa Ishidome et al.EBioMedicine, 22, 89-99 (2017-07-25) Liquiritigenin restores osteoblast damage through regulating oxidative stress and mitochondrial dysfunction.Eun Mi Choi et al.Phytotherapy research : PTR, 28(6), 880-886 (2013-10-15) Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells.Liping Xu et al.Molecular medicine reports, 20(1), 613-621 (2019-05-23) Carnosic acid induces apoptosis associated with mitochondrial dysfunction and Akt inactivation in HepG2 cells.Qisen Xiang et al.International journal of food sciences and nutrition, 66(1), 76-84 (2014-09-30) Half-sandwich Os(ii) and Ru(ii) bathophenanthroline complexes: anticancer drug candidates with unusual potency and a cellular activity profile in highly invasive triple-negative breast cancer cells.Jitka Pracharova et al.Dalton transactions (Cambridge, England : 2003), 47(35), 12197-12208 (2018-08-17) High Surface Reactivity and Biocompatibility of Y2O3 NPs in Human MCF-7 Epithelial and HT-1080 FibroBlast Cells.Mohd Javed Akhtar et al.Molecules (Basel, Switzerland), 25(5) (2020-03-07) Induction of apoptosis in MDA-MB-231 human breast carcinoma cells with an ethanol extract of Cyperus rotundus L. by activating caspases.Sang Eun Park et al.Oncology reports, 32(6), 2461-2470 (2014-09-23) Favourable metabolic profile sustains mitophagy and prevents metabolic abnormalities in metabolically healthy obese individuals.Shipra Bhansali et al.Diabetology & metabolic syndrome, 9, 99-99 (2017-12-20) Centella asiatica Fraction-3 Suppresses the Nuclear Factor Erythroid 2-Related Factor 2 Anti-Oxidant Pathway and Enhances Reactive Oxygen Species-Mediated Cell Death in Cancerous Lung A549 Cells.Dhaneshree Bestinee Naidoo et al.Journal of medicinal food, 20(10), 959-968 (2017-10-19) Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.Eun Ji Joo et al.Chemico-biological interactions, 233, 25-34 (2015-04-01) Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells.Y Dong et al.European review for medical and pharmacological sciences, 23(3), 1047-1054 (2019-02-20) A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.Anja Bastian et al.The Journal of pharmacology and experimental therapeutics, 353(2), 392-404 (2015-02-28) Insulin-like growth factor II receptor-α is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.Sudhir Pandey et al.American journal of physiology. Cell physiology, 317(2), C235-C243 (2019-05-23) Gadolinium Oxide Nanoparticles Induce Toxicity in Human Endothelial HUVECs via Lipid Peroxidation, Mitochondrial Dysfunction and Autophagy Modulation.Mohd Javed Akhtar et al.Nanomaterials (Basel, Switzerland), 10(9) (2020-08-30) α-Mangostin reduced the viability of A594 cells in vitro by provoking ROS production through downregulation of NAMPT/NAD.Yan-Yun Ding et al.Cell stress & chaperones, 25(1), 163-172 (2020-01-04) Changshuang Fu et al.Oncology letters, 17(1), 303-313 (2019-01-19)Cistanche tubulosa has various biological functions. In the present study, the antitumor effect of water-soluble phenylethanoid glycosides of C. tubulosa (CTPG-W) on esophageal cancer was investigated. Eca-109 cells were treated with CTPG-W and the cell viability was measured by MTT... Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells.Jingchao Wu et al.Journal of neuro-oncology, 120(1), 33-41 (2014-07-23) Synergized Multimodal Therapy for Safe and Effective Reversal of Cancer Multidrug Resistance Based on Low-Level Photothermal and Photodynamic Effects.Luming Xu et al.Small (Weinheim an der Bergstrasse, Germany), e1800785-e1800785 (2018-06-23) Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics.Florian Engert et al.Oncotarget, 8(30), 48794-48806 (2016-07-23) Induction of apoptosis and cell cycle arrest by ethyl acetate fraction of Phoenix dactylifera L. (Ajwa dates) in prostate cancer cells.Muqtadir Baig Mirza et al.Journal of ethnopharmacology, 218, 35-44 (2018-02-25) Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury.Lan Li et al.Journal of controlled release : official journal of the Controlled Release Society, 317, 259-272 (2019-11-30) Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway.Tso-Ting Lai et al.Antioxidants (Basel, Switzerland), 9(8) (2020-08-14) Divergent roles of three cytochrome c in CTSB-modulating coelomocyte apoptosis in Apostichopus japonicus.Huahui Chen et al.Developmental and comparative immunology, 76, 65-76 (2017-05-28) ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics.Zhongqi Fan et al.Experimental cell research, 335(1), 68-81 (2015-05-06) Cellular uptake of paraquat determines subsequent toxicity including mitochondrial damage in lung epithelial cells.Sanae Kanno et al.Legal medicine (Tokyo, Japan), 37, 7-14 (2018-12-07) Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78.Youli Cai et al.Cell death & disease, 9(6), 636-636 (2018-05-29) Glucagon-like peptide-1 receptor agonist stimulates mitochondrial bioenergetics in human adipocytes.Joanna Góralska et al.Acta biochimica Polonica, 64(3), 423-429 (2017-08-22) Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells.Haobin Zhao et al.AMB Express, 8(1), 78-78 (2018-05-20) High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway.Guo-Sheng Zhao et al.American journal of translational research, 11(4), 2117-2139 (2019-05-21) Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA.Min Kang et al.Molecular cancer, 19(1), 143-143 (2020-09-16) pH-sensitive pluronic micelles combined with oxidative stress amplification for enhancing multidrug resistance breast cancer therapy.Xu Cheng et al.Journal of colloid and interface science, 565, 254-269 (2020-01-25) Berberine Promotes Cardiac Function by Upregulating PINK1/Parkin-Mediated Mitophagy in Heart Failure.Miyesaier Abudureyimu et al.Frontiers in physiology, 11, 565751-565751 (2020-10-27) Four-octyl itaconate activates Nrf2 cascade to protect osteoblasts from hydrogen peroxide-induced oxidative injury.Yuehuan Zheng et al.Cell death & disease, 11(9), 772-772 (2020-09-19) Mitochondrion-targeted selenium nanoparticles enhance reactive oxygen species-mediated cell death.Yuan Zhuang et al.Nanoscale, 12(3), 1389-1396 (2020-01-09) Auranofin, an inhibitor of thioredoxin reductase, induces apoptosis in hepatocellular carcinoma Hep3B cells by generation of reactive oxygen species.Hyun Hwang-Bo et al.General physiology and biophysics, 36(2), 117-128 (2017-02-22) Two repeated low doses of doxorubicin are more effective than a single high dose against tumors overexpressing P-glycoprotein.Chiara Riganti et al.Cancer letters, 360(2), 219-226 (2015-02-15) Role of monocarboxylate transporter 4 in Alzheimer disease.Ping Hong et al.Neurotoxicology, 76, 191-199 (2019-11-19) Single wavelength light-mediated, synergistic bimodal cancer photoablation and amplified photothermal performance by graphene/gold nanostar/photosensitizer theranostics.Chunhui Wu et al.Acta biomaterialia, 53, 631-642 (2017-02-06) High glucose induces apoptosis of HUVECs in a mitochondria-dependent manner by suppressing hexokinase 2 expression.Jia Zhang et al.Experimental and therapeutic medicine, 18(1), 621-629 (2019-07-02) Huaier Restrains Cholangiocarcinoma Progression in vitro and in vivo Through Modulating lncRNA TP73-AS1 and Inducing Oxidative Stress.Daolin Ji et al.OncoTargets and therapy, 13, 7819-7837 (2020-08-28) Dual-targeting of aberrant glucose metabolism in glioblastoma.Han Shen et al.Journal of experimental & clinical cancer research : CR, 34, 14-14 (2015-02-06) Dioscin facilitates ROS-induced apoptosis via the p38-MAPK/HSP27-mediated pathways in lung squamous cell carcinoma.Yinan Yao et al.International journal of biological sciences, 16(15), 2883-2894 (2020-10-17) miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway.Yuchen Li et al.Stem cell research & therapy, 11(1), 330-330 (2020-10-27) B lymphocytes undergo TLR2-dependent apoptosis upon Shigella infection.Katharina Nothelfer et al.The Journal of experimental medicine, 211(6), 1215-1229 (2014-05-28) Disturbed mitochondrial quality control involved in hepatocytotoxicity induced by silica nanoparticles.Yi Qi et al.Nanoscale, 12(24), 13034-13045 (2020-06-17) Rifampicin inhibits rotenone-induced microglial inflammation via enhancement of autophagy.Yanran Liang et al.Neurotoxicology, 63, 137-145 (2017-10-08) In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics.Angèle Nalbandian et al.Mitochondrion, 22, 1-8 (2015-03-01) Chlorogenic acid protects against aluminium-induced cytotoxicity through chelation and antioxidant actions in primary hippocampal neuronal cells.Xiaomei Wang et al.Food & function, 8(8), 2924-2934 (2017-07-27) Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS.Xianzhi Qu et al.PloS one, 12(3), e0173712-e0173712 (2017-03-17) A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H2O2-Induced Cytotoxicity in SH-SY5Y Cells.Chen Cheng et al.Neurochemical research, 45(9), 2113-2127 (2020-06-20) Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-κB pathways.Yuying Huang et al.Food & function, 11(1), 596-605 (2019-12-21) Effect of cysteine and glutamine added to extender on post-thaw sperm functional parameters of buffalo bull.T R Topraggaleh et al.Andrologia, 46(7), 777-783 (2013-08-21) T-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor.Hyosun Tak et al.Cell death and differentiation, 24(1), 49-58 (2016-09-10) Phenalenone-photodynamic therapy induces apoptosis on human tumor cells mediated by caspase-8 and p38-MAPK activation.María L Salmerón et al.Molecular carcinogenesis, 57(11), 1525-1539 (2018-07-24) BCI induces apoptosis via generation of reactive oxygen species and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.Jong-Woon Shin et al.Science China. Life sciences, 61(10), 1243-1253 (2018-03-11) Melatonin prevents postovulatory oocyte aging and promotes subsequent embryonic development in the pig.Tao Wang et al.Aging, 9(6), 1552-1564 (2017-06-29) Growth inhibition and apoptosis induction by alternol in pancreatic carcinoma cells.Pei-Fang Cong et al.World journal of gastroenterology, 21(15), 4526-4535 (2015-04-29) Luteolin Attenuates Doxorubicin-Induced Cardiotoxicity Through Promoting Mitochondrial Autophagy.Haixia Xu et al.Frontiers in physiology, 11, 113-113 (2020-03-03) Resveratrol inhibits aflatoxin B1-induced oxidative stress and apoptosis in bovine mammary epithelial cells and is involved the Nrf2 signaling pathway.Yongfeng Zhou et al.Toxicon : official journal of the International Society on Toxinology, 164, 10-15 (2019-04-05) Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy.Xiu-Wu Pan et al.Oncology reports, 35(1), 334-342 (2015-10-27) Deltamethrin exposure induces oxidative stress and affects meiotic maturation in mouse oocyte.Zhen-Zhen Jia et al.Chemosphere, 223, 704-713 (2019-02-26) A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.Jeong Eon Park et al.Biomolecules & therapeutics, 25(4), 404-410 (2017-05-31) Edaravone Attenuates the Proinflammatory Response in Amyloid-β-Treated Microglia by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion.Hong-Mei Wang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(3), 1113-1125 (2017-10-05) microRNA-579 upregulation mediates death of human macrophages with mycobacterium tuberculosis infection.Jun Ma et al.Biochemical and biophysical research communications, 518(2), 219-226 (2019-08-23) miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway.Yuchen Li et al.Stem cell research & therapy, 11(1), 330-330 (2020-10-27) B lymphocytes undergo TLR2-dependent apoptosis upon Shigella infection.Katharina Nothelfer et al.The Journal of experimental medicine, 211(6), 1215-1229 (2014-05-28) Disturbed mitochondrial quality control involved in hepatocytotoxicity induced by silica nanoparticles.Yi Qi et al.Nanoscale, 12(24), 13034-13045 (2020-06-17) Huaier Restrains Cholangiocarcinoma Progression in vitro and in vivo Through Modulating lncRNA TP73-AS1 and Inducing Oxidative Stress.Daolin Ji et al.OncoTargets and therapy, 13, 7819-7837 (2020-08-28) Dual-targeting of aberrant glucose metabolism in glioblastoma.Han Shen et al.Journal of experimental & clinical cancer research : CR, 34, 14-14 (2015-02-06) Dioscin facilitates ROS-induced apoptosis via the p38-MAPK/HSP27-mediated pathways in lung squamous cell carcinoma.Yinan Yao et al.International journal of biological sciences, 16(15), 2883-2894 (2020-10-17) Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA.Min Kang et al.Molecular cancer, 19(1), 143-143 (2020-09-16) pH-sensitive pluronic micelles combined with oxidative stress amplification for enhancing multidrug resistance breast cancer therapy.Xu Cheng et al.Journal of colloid and interface science, 565, 254-269 (2020-01-25) Berberine Promotes Cardiac Function by Upregulating PINK1/Parkin-Mediated Mitophagy in Heart Failure.Miyesaier Abudureyimu et al.Frontiers in physiology, 11, 565751-565751 (2020-10-27) Effects of fluorescent carbon dots from the baked lamb on energy and lipid metabolism.Lijuan Zhang et al.Food chemistry, 338, 127832-127832 (2020-08-21) Transfer of healthy fibroblast-derived mitochondria to HeLa ρ0 and SAS ρ0 cells recovers the proliferation capabilities of these cancer cells under conventional culture medium, but increase their sensitivity to cisplatin-induced apoptotic death.Amaneh Mohammadi Roushandeh et al.Molecular biology reports, 47(6), 4401-4411 (2020-05-13) Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.Jilong Zou et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(5), 1812-1821 (2017-07-28) Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.Daojuan Wang et al.Journal of translational medicine, 18(1), 84-84 (2020-02-19) Discovery of novel pyrazoline derivatives containing methyl-1H-indole moiety as potential inhibitors for blocking APC-Asef interactions.Peng-Fei Qi et al.Bioorganic chemistry, 99, 103838-103838 (2020-04-26) Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function.Jin-Huan Jiang et al.Pathology, research and practice, 214(5), 691-699 (2018-03-24) Combined toxicity of prevalent mycotoxins studied in fish cell line and zebrafish larvae revealed that type of interactions is dose-dependent.Hongyuan Zhou et al.Aquatic toxicology (Amsterdam, Netherlands), 193, 60-71 (2017-10-19) Apoptotic-like changes in epididymal spermatozoa of soft-shelled turtles, Pelodiscus sinensis, during long-term storage at 4 ºC.Hong Chen et al.Animal reproduction science, 205, 134-143 (2019-05-08) The augmentation of O-GlcNAcylation reduces glyoxal-induced cell injury by attenuating oxidative stress in human retinal microvascular endothelial cells.Guo Dong Liu et al.International journal of molecular medicine, 36(4), 1019-1027 (2015-08-28) Calenduloside E Ameliorates Myocardial Ischemia-Reperfusion Injury through Regulation of AMPK and Mitochondrial OPA1.Min Wang et al.Oxidative medicine and cellular longevity, 2020, 2415269-2415269 (2020-09-17) Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson's disease model.Mi Jin Kim et al.Biomaterials, 64, 45-56 (2015-06-29) Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse.Gerardo Ramos-Mandujano et al.Stem cell research, 12(3), 690-702 (2014-04-01) The Combination of Glycolytic Inhibitor 2-Deoxyglucose and Microbubbles Increases the Effect of 5-Aminolevulinic Acid-Sonodynamic Therapy in Liver Cancer Cells.Rui Xie et al.Ultrasound in medicine & biology, 43(11), 2640-2650 (2017-08-28) Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.Gil Mendes Viana et al.Chemical & pharmaceutical bulletin, 65(10), 911-919 (2017-10-03) Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-CaJing Zhang et al.Oncotarget, 8(53), 91223-91237 (2017-12-07) Protective Effect of N-Acetylcysteine against Oxidative Stress Induced by Zearalenone via Mitochondrial Apoptosis Pathway in SIEC02 Cells.Jingjing Wang et al.Toxins, 10(10) (2018-10-12) BST204, a Rg3 and Rh2 Enriched Ginseng Extract, Upregulates Myotube Formation and Mitochondrial Function in TNF-α-Induced Atrophic Myotubes.Sang-Jin Lee et al.The American journal of Chinese medicine, 48(3), 631-650 (2020-04-25) Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.Junru Wen et al.International journal of molecular medicine, 45(3), 873-885 (2020-01-11) Exogenous hydrogen sulfide restores cardioprotection of ischemic post-conditioning via inhibition of mPTP opening in the aging cardiomyocytes.Hongzhu Li et al.Cell & bioscience, 5, 43-43 (2015-08-01) (20S)-Protopanaxadiol Ginsenosides Induced Cytotoxicity via Blockade of Autophagic Flux in HGC-27 Cells.Qingqing Han et al.Chemistry & biodiversity, 17(7), e2000187-e2000187 (2020-05-10) Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells.Kan Yin et al.Stem cells and development, 26(10), 762-775 (2017-02-10) Activation of the Nrf2-ARE Pathway Ameliorates Hyperglycemia-Mediated Mitochondrial Dysfunction in Podocytes Partly Through Sirt1.Qunzi Zhang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(1), 1-15 (2018-07-12) Simulation of hypoxia of myocardial cells in microfluidic systems.Anna Kobuszewska et al.Scientific reports, 10(1), 15524-15524 (2020-09-25) Reducing-Autophagy Derived Mitochondrial Dysfunction during Resveratrol Promotes Fibroblast-Like Synovial Cell Apoptosis.Wei Cao et al.Anatomical record (Hoboken, N.J. : 2007), 301(7), 1179-1188 (2018-02-21) Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression.Peng Shen et al.Cell death & disease, 11(5), 362-362 (2020-05-15) Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells.Zhanpeng Yan et al.BMC complementary and alternative medicine, 19(1), 151-151 (2019-06-28) The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells.Agnieszka Gornowicz et al.International journal of molecular sciences, 21(15) (2020-07-29) Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.Shinji Ohkubo et al.International journal of oncology, 54(6), 2080-2094 (2019-05-14) Enhanced Aerobic Glycolysis by S-Nitrosoglutathione via HIF-1α Associated GLUT1/Aldolase A Axis in Human Endothelial Cells.Jieping Yan et al.Journal of cellular biochemistry, 118(8), 2443-2453 (2017-01-26) Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress.Yi Yang et al.Food & function, 11(5), 4171-4184 (2020-05-01) Mitochondrial transplantation attenuates lipopolysaccharide- induced depression-like behaviors.Yun Wang et al.Progress in neuro-psychopharmacology & biological psychiatry, 93, 240-249 (2019-04-26) Centella asiatica Fraction-3 Suppresses the Nuclear Factor Erythroid 2-Related Factor 2 Anti-Oxidant Pathway and Enhances Reactive Oxygen Species-Mediated Cell Death in Cancerous Lung A549 Cells.Dhaneshree Bestinee Naidoo et al.Journal of medicinal food, 20(10), 959-968 (2017-10-19) Platinum(II) ring-fused chlorins as efficient theranostic agents: Dyes for tumor-imaging and photodynamic therapy of cancer.Mafalda Laranjo et al.European journal of medicinal chemistry, 200, 112468-112468 (2020-06-09) Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives-Biological Activity Towards Cancer Cells.Jakub Iwanejko et al.Materials (Basel, Switzerland), 13(10) (2020-05-28) The Antioxidant from Ethanolic Extract of Rosa cymosa Fruits Activates Phosphatase and Tensin Homolog In Vitro and In Vivo: A New Insight on Its Antileukemic Effect.Kuan-Chih Wang et al.International journal of molecular sciences, 20(8) (2019-04-24) Baicalein attenuates impairment of hepatic lysosomal acidification induced by high fat diet via maintaining V-ATPase assembly.Xinhong Zhu et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 136, 110990-110990 (2019-11-24) Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562.Pinar Mega Tiber et al.Gene, 692, 217-222 (2019-01-27) Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway.Yanji Cui et al.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 23(2), 121-130 (2019-03-02) Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells.Ling Liu et al.Journal of experimental & clinical cancer research : CR, 37(1), 142-142 (2018-07-11) Neuroprotective Effects of an Aqueous Extract of Forsythia viridissima and Its Major Constituents on Oxaliplatin-Induced Peripheral Neuropathy.Jin-Mu Yi et al.Molecules (Basel, Switzerland), 24(6) (2019-04-03) Role of autophagy in the chemopreventive effect of the IFC-305 compound in the sequential model of cirrhosis-hepatocellular carcinoma in the rat and in vitro.Enrique Chávez et al.American journal of cancer research, 10(6), 1844-1856 (2020-07-10) Brusatol Protects HepG2 Cells against Oxygen-Glucose Deprivation-Induced Injury via Inhibiting Mitochondrial Reactive Oxygen Species-Induced Oxidative Stress.Shajun Zhu et al.Pharmacology, 105(7-8), 416-423 (2019-12-12) Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function.Diego Mastroeni et al.ACS chemical neuroscience, 6(4), 588-598 (2015-02-11) Oxidative damage to mitochondria at the nodes of Ranvier precedes axon degeneration in ex vivo transected axons.Helena Bros et al.Experimental neurology, 261, 127-135 (2014-06-29) Expression of GRIM-19 in missed abortion and possible pathogenesis.Honglei Chen et al.Fertility and sterility, 103(1), 138-146 (2014-12-03) The antimicrobial peptide nisin Z induces selective toxicity and apoptotic cell death in cultured melanoma cells.Angélique Lewies et al.Biochimie, 144, 28-40 (2017-10-22) Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage.Xin Tan et al.Frontiers in pharmacology, 10, 1551-1551 (2020-02-11) Excessive zinc chloride induces murine photoreceptor cell death via reactive oxygen species and mitochondrial signaling pathway.Hui Wang et al.Journal of inorganic biochemistry, 187, 25-32 (2018-07-25) Mitochondrial membrane potential in 2-cell stage embryos correlates with the success of preimplantation development.Kouji Komatsu et al.Reproduction (Cambridge, England), 147(5), 627-638 (2014-01-25) β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression.Ang Zhao et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 69, 153183-153183 (2020-03-01) Diabetes aggravates renal ischemia-reperfusion injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy.Yuan-Yuan Yang et al.American journal of physiology. Renal physiology, 317(4), F852-F864 (2019-08-08) Grifolic acid causes osteosarcoma cell death in vitro and in tumor-bearing mice.Yu-Feng Zhao et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 1035-1042 (2018-05-02) The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in vitro.Nazli Kuter et al.Neonatology, 113(4), 360-365 (2018-03-07) Induction of oxidative stress biomarkers following whole-body irradiation in mice.Tsutomu Shimura et al.PloS one, 15(10), e0240108-e0240108 (2020-10-02) Induction of apoptosis by ethanol extract of Citrus unshiu Markovich peel in human bladder cancer T24 cells through ROS-mediated inactivation of the PI3K/Akt pathway.Kyu Im Ahn et al.Bioscience trends, 11(5), 565-573 (2017-10-27) Interaction of α-synuclein and Parkin in iron toxicity on SH-SY5Y cells: implications in the pathogenesis of Parkinson's disease.Upasana Ganguly et al.The Biochemical journal, 477(6), 1109-1122 (2020-02-29) Pinellia pedatisecta lectin exerts a proinflammatory activity correlated with ROS-MAPKs/NF-κB pathways and the NLRP3 inflammasome in RAW264.7 cells accompanied by cell pyroptosis.Wei Wang et al.International immunopharmacology, 66, 1-12 (2018-11-12) Selenium attenuates apoptosis and p-AMPK expressions in fluoride-induced NRK-52E cells.Jiping Gao et al.Environmental science and pollution research international, 26(15), 15685-15697 (2019-04-06) Autophagy plays an important role in triptolide-induced apoptosis in cardiomyocytes.Jie Zhou et al.Toxicology letters, 236(3), 168-183 (2015-05-27) Layered double hydroxide eliminate embryotoxicity of chemotherapeutic drug through BMP-SMAD signaling pathway.Zhaojie Wang et al.Biomaterials, 230, 119602-119602 (2019-11-19) Mitigation in Multiple Effects of Graphene Oxide Toxicity in Zebrafish Embryogenesis Driven by Humic Acid.Yuming Chen et al.Environmental science & technology, 49(16), 10147-10154 (2015-07-15) Ethyl acetate extract of Caesalpinia sappan L. inhibited acute myeloid leukemia via ROS-mediated apoptosis and differentiation.Hao-Yue Ma et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 68, 153142-153142 (2020-02-12) Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer's disease.Hui Wang et al.Toxicology letters, 282, 100-108 (2017-11-04) Activation of Nrf2 signaling by oltipraz inhibits death of human macrophages with mycobacterium tuberculosis infection.Qin Sun et al.Biochemical and biophysical research communications, 531(3), 312-319 (2020-08-18) DNMT and HDAC inhibitors together abrogate endotoxemia mediated macrophage death by STAT3-JMJD3 signaling.Saheli Samanta et al.The international journal of biochemistry & cell biology, 102, 117-127 (2018-07-17) Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells.Soyeon Jeong et al.Cancers, 11(6) (2019-06-15) Pre-arrest hypothermia improved cardiac function of rats by ameliorating the myocardial mitochondrial injury after cardiac arrest.Yuanzheng Lu et al.Experimental biology and medicine (Maywood, N.J.), 244(14), 1186-1192 (2019-09-19) Ocean acidification impacts on sperm mitochondrial membrane potential bring sperm swimming behaviour near its tipping point.Peter Schlegel et al.The Journal of experimental biology, 218(Pt 7), 1084-1090 (2015-04-04) Improvement of mitochondrial function mediated the neuroprotective effect of 5-(4-hydroxy-3-dimethoxybenzylidene)-2-thioxo-4-thiazolidinone in rats with cerebral ischemia-reperfusion injuries.Mingyang Wang et al.Oncotarget, 8(37), 61193-61202 (2017-10-06) Fusaricidin-Type Compounds Create Pores in Mitochondrial and Plasma Membranes of Mammalian Cells.Raimo Mikkola et al.Biomolecules, 9(9) (2019-09-05) MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity.Xibo Jing et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(2), 692-704 (2018-07-20) Effect of 1,2,3-triazole salts, non-classical bioisosteres of miltefosine, on Leishmania amazonensis.Pedro H F Stroppa et al.Bioorganic & medicinal chemistry, 25(12), 3034-3045 (2017-04-24) SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.Dejun Xu et al.Life sciences, 232, 116639-116639 (2019-07-12) Apelin-13 Administration Protects Against LPS-Induced Acute Lung Injury by Inhibiting NF-κB Pathway and NLRP3 Inflammasome Activation.Hailin Zhang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(5), 1918-1932 (2018-09-21) Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis.Yue Li et al.Theranostics, 10(7), 2897-2917 (2020-03-21) circARF3 Alleviates Mitophagy-Mediated Inflammation by Targeting miR-103/TRAF3 in Mouse Adipose Tissue.Zhenzhen Zhang et al.Molecular therapy. Nucleic acids, 14, 192-203 (2019-01-10) The Combination Effect of Aspalathin and Phenylpyruvic Acid-2-O-β-D-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study.Phiwayinkosi V Dludla et al.Nutrients, 12(4) (2020-04-25) Platinum nanoparticles induced genotoxicity and apoptotic activity in human normal and cancer hepatic cells via oxidative stress-mediated Bax/Bcl-2 and caspase-3 expression.Mohammed H A Almarzoug et al.Environmental toxicology, 35(9), 930-941 (2020-04-21) Hypericin damages the ectatic capillaries in a Roman cockscomb model and inhibits the growth of human endothelial cells more potently than hematoporphyrin does through induction of apoptosis.Zhuo-heng Li et al.Photochemistry and photobiology, 90(6), 1368-1375 (2014-07-30) Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin.Lele Guo et al.PloS one, 10(4), e0124002-e0124002 (2015-04-14) Attenuation of doxorubicin-induced cardiotoxicity by cryptotanshinone detected through association analysis of transcriptomic profiling and KEGG pathway.Le Li et al.Aging, 12(10), 9585-9603 (2020-05-28) Centchroman induces redox-dependent apoptosis and cell-cycle arrest in human endometrial cancer cells.Hari Shyam et al.Apoptosis : an international journal on programmed cell death, 22(4), 570-584 (2017-02-09) Effects of TLR4 overexpression on sperm quality, seminal plasma biomarkers, sperm DNA methylation and pregnancy rate in sheep.Yi Fang et al.Theriogenology, 142, 368-375 (2019-11-13) Design, synthesis and anticancer properties of novel oxa/azaspiro[4,5]trienones as potent apoptosis inducers through mitochondrial disruption.D Yugandhar et al.European journal of medicinal chemistry, 101, 348-357 (2015-07-15) Design and synthesis of imidazolidinone derivatives as potent anti-leishmanial agents by bioisosterism.Dandugudumula Ramu et al.Archiv der Pharmazie, 352(4), e1800290-e1800290 (2019-02-26) Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.Seog-Young Kim et al.Apoptosis : an international journal on programmed cell death, 19(11), 1603-1615 (2014-08-27) Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury.Wei Chen et al.Theranostics, 10(13), 5879-5894 (2020-06-03) Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1.Toshiyuki Matsunaga et al.Chemico-biological interactions, 279, 10-20 (2017-11-08) Glucocorticoids impair oocyte competence and trigger apoptosis of ovarian cells via activating the TNF-α system.Hong-Jie Yuan et al.Reproduction (Cambridge, England), 160(1), 129-140 (2020-06-03) BDNF-mediated mitophagy alleviates high-glucose-induced brain microvascular endothelial cell injury.Hong Jin et al.Apoptosis : an international journal on programmed cell death, 24(5-6), 511-528 (2019-03-17) Inhibition of Inositol 1, 4, 5-Trisphosphate Receptor Induce Breast Cancer Cell Death Through Deregulated Autophagy and Cellular Bioenergetics.Aru Singh et al.Journal of cellular biochemistry, 118(8), 2333-2346 (2017-01-21) Sibutramine facilitates apoptosis and contraction of aortic smooth muscle cells through elevating production of reactive oxygen species.Yoshifumi Morikawa et al.European journal of pharmacology, 841, 113-121 (2018-10-20) Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway.Wenqin Xiao et al.Cancer letters, 444, 45-59 (2018-12-26) Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer.Wenjie Guo et al.Autophagy, 10(6), 972-985 (2014-06-01) β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression.Ang Zhao et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 69, 153183-153183 (2020-03-01) Diabetes aggravates renal ischemia-reperfusion injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy.Yuan-Yuan Yang et al.American journal of physiology. Renal physiology, 317(4), F852-F864 (2019-08-08) Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.Ke Wang et al.Anti-cancer drugs, 26(1), 15-24 (2014-09-18) Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway.Yujie Huang et al.Aging, 11(8), 2217-2240 (2019-04-17) Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells.Waleed F A Marei et al.Scientific reports, 9(1), 3673-3673 (2019-03-08) Ephedrine-induced mitophagy via oxidative stress in human hepatic stellate cells.Ah Young Lee et al.The Journal of toxicological sciences, 42(4), 461-473 (2017-07-19) Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cells.Jenn-Haung Lai et al.EMBO reports, 19(8) (2018-06-09) Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome.Hiroki Kato et al.Biochemical and biophysical research communications, 493(1), 207-212 (2017-09-14) Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection.Qi-Wen Wang et al.Molecular medicine reports, 12(3), 4448-4454 (2015-06-13) Overcoming Multidrug Resistance through the GLUT1-Mediated and Enzyme-Triggered Mitochondrial Targeting Conjugate with Redox-Sensitive Paclitaxel Release.Pengkai Ma et al.ACS applied materials & interfaces, 10(15), 12351-12363 (2018-03-24) Sulfate Aerosols Promote Lung Cancer Metastasis by Epigenetically Regulating the Epithelial-to-Mesenchymal Transition (EMT).Yang Yun et al.Environmental science & technology, 51(19), 11401-11411 (2017-09-14) Sodium Fluoride Induces Apoptosis in H9c2 Cardiomyocytes by Altering Mitochondrial Membrane Potential and Intracellular ROS Level.Xiaoyan Yan et al.Biological trace element research, 166(2), 210-215 (2015-02-25) Co-treatment of breast cancer cells with pharmacologic doses of 2-deoxy-D-glucose and metformin: Starving tumors.Ulrike Wokoun et al.Oncology reports, 37(4), 2418-2424 (2017-03-30) β-Carbolines in Experiments on Laboratory Animals.Renata Zawirska-Wojtasiak et al.International journal of molecular sciences, 21(15) (2020-07-30) Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen peroxide.Yunchuan Zhou et al.International journal of molecular medicine, 36(1), 43-52 (2015-05-09) Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells.Xianghong Lei et al.Mediators of inflammation, 2020, 3934769-3934769 (2020-09-04) Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade.Lin Liu et al.Developmental cell, 52(2), 196-209 (2019-12-24) Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention.Subhadeep Roy et al.Oncotarget, 8(41), 70049-70071 (2017-10-21) Luteolin alleviates cardiac ischemia/reperfusion injury in the hypercholesterolemic rat via activating Akt/Nrf2 signaling.Jin-Ting Yang et al.Naunyn-Schmiedeberg's archives of pharmacology, 391(7), 719-728 (2018-04-20) A novel lead compound CM-118: antitumor activity and new insight into the molecular mechanism and combination therapy strategy in c-Met- and ALK-dependent cancers.Lanfang Meng et al.Cancer biology & therapy, 15(6), 721-734 (2014-03-13) Alda-1, an ALDH2 activator, protects against hepatic ischemia/reperfusion injury in rats via inhibition of oxidative stress.Tao Zhang et al.Free radical research, 52(6), 629-638 (2018-03-29) A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction.Xuanxuan Dai et al.Cancer management and research, 10, 3069-3082 (2018-09-15) In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer.Zhigao Wang et al.ACS applied materials & interfaces, 10(48), 41056-41069 (2018-11-06) Polystyrene nanoplastics cause growth inhibition, morphological damage and physiological disturbance in the marine microalga Platymonas helgolandica.Shuyu Wang et al.Marine pollution bulletin, 158, 111403-111403 (2020-08-06) HMGB1 contributes to adriamycin-induced cardiotoxicity via up-regulating autophagy.Peihua Luo et al.Toxicology letters, 292, 115-122 (2018-05-02) Morin hydrate attenuates CSE-induced lipid accumulation, ER stress, and oxidative stress in RPE cells: implications for age-related macular degeneration.Sung Hwan Kim et al.Free radical research, 53(8), 865-874 (2019-07-02) Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.Ting Yang et al.Toxicology in vitro : an international journal published in association with BIBRA, 66, 104868-104868 (2020-04-23) The neuroprotective effects of taurine against nickel by reducing oxidative stress and maintaining mitochondrial function in cortical neurons.Shangcheng Xu et al.Neuroscience letters, 590, 52-57 (2015-02-01) Selective Inhibition of PKCβ2 Restores Ischemic Postconditioning-Mediated Cardioprotection by Modulating Autophagy in Diabetic Rats.Yafeng Wang et al.Journal of diabetes research, 2020, 2408240-2408240 (2020-04-28) Sirtuin‑1 protects hair follicle stem cells from TNFα-mediated inflammatory stress via activating the MAPK-ERK-Mfn2 pathway.Jingjing Liu et al.Life sciences, 212, 213-224 (2018-10-08) Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance.Kelsey J Yamada et al.PLoS pathogens, 16(3), e1008354-e1008354 (2020-03-07) Treatment of acetaminophen-induced liver injury with exogenous mitochondria in mice.Xianxun Shi et al.Translational research : the journal of laboratory and clinical medicine, 196, 31-41 (2018-03-20) Apoptosis and necrosis induced by novel realgar quantum dots in human endometrial cancer cells via endoplasmic reticulum stress signaling pathway.Huan Wang et al.International journal of nanomedicine, 10, 5505-5512 (2015-09-12) Modulation of mitochondrial function by stem cell-derived cellular components.Tian Liu et al.Biochemical and biophysical research communications, 448(4), 403-408 (2014-05-08) Protective effect of a 3 kDa peptide obtained from beef myofibrillar protein using alkaline-AK on neuronal cells.Seung Yun Lee et al.Neurochemistry international, 129, 104459-104459 (2019-05-12) Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.Xiayun Yang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 105, 161-176 (2017-03-28) Connexin 43 enhances Bax activation via JNK activation in sunitinib-induced apoptosis in mesothelioma cells.Miaki Uzu et al.Journal of pharmacological sciences, 134(2), 101-107 (2017-06-13) Imperatorin induces Mcl-1 degradation to cooperatively trigger Bax translocation and Bak activation to suppress drug-resistant human hepatoma.Xia Li et al.Cancer letters, 348(1-2), 146-155 (2014-04-01) Platelet microRNA-15b protects against high platelet reactivity in patients undergoing percutaneous coronary intervention through Bcl-2-mediated platelet apoptosis.Jinghan Wang et al.Annals of translational medicine, 8(6), 364-364 (2020-05-02) Stable expression of infliximab in CRISPR/Cas9-mediated BAK1-deficient CHO cells.Zhi Miao et al.Biotechnology letters (2018-06-20) ARV-825-induced BRD4 protein degradation as a therapy for thyroid carcinoma.Ling He et al.Aging, 12(5), 4547-4557 (2020-03-13) Effect of polyethylene glycol surface charge functionalization of SWCNT on the in vitro and in vivo nanotoxicity and biodistribution monitored noninvasively using MRI.Asma Sultana Shaik et al.Toxicology mechanisms and methods, 29(4), 233-243 (2018-11-28) Neuroprotective effects of torularhodin against H2O2-induced oxidative injury and apoptosis in PC12 cells.Jia-Ling Wu et al.Die Pharmazie, 70(1), 17-23 (2015-05-16) γδ T Cells Kill Plasmodium falciparum in a Granzyme- and Granulysin-Dependent Mechanism during the Late Blood Stage.Maria Andrea Hernández-Castañeda et al.Journal of immunology (Baltimore, Md. : 1950), 204(7), 1798-1809 (2020-02-19) Inhibition of aerobic glycolysis enhances the anti-tumor efficacy of Zoptarelin Doxorubicin in triple-negative breast cancer cells.Carsten Gründker et al.The journal of obstetrics and gynaecology research, 45(7), 1334-1342 (2019-04-25) Adapentpronitrile, a New Dipeptidyl Peptidase-IV Inhibitor, Ameliorates Diabetic Neuronal Injury Through Inhibiting Mitochondria-Related Oxidative Stress and Apoptosis.Lu Yang et al.Frontiers in cellular neuroscience, 12, 214-214 (2018-08-04) Metallic wear debris collected from patients induces apoptosis in rat primary osteoblasts via reactive oxygen species‑mediated mitochondrial dysfunction and endoplasmic reticulum stress.Fei Yang et al.Molecular medicine reports, 19(3), 1629-1637 (2019-01-11) Restoring mitochondrial function and normalizing ROS-JNK/MAPK pathway exert key roles in glutamine ameliorating bisphenol A-induced intestinal injury.Ning Jiao et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(6), 7442-7461 (2020-04-15) Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection.Daniela Surico et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(6), 2108-2120 (2015-08-19) Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.Wanda van der Stel et al.Archives of toxicology, 94(8), 2707-2729 (2020-07-02) Carmustine induces platelet apoptosis.Jie Zhang et al.Platelets, 26(5), 437-442 (2014-06-24) Overexpression of IκBα in cardiomyocytes alleviates hydrogen peroxide-induced apoptosis and autophagy by inhibiting NF-κB activation.Min Han et al.Lipids in health and disease, 19(1), 150-150 (2020-06-26) Ferrocene-cinchona hybrids with triazolyl-chalcone linkers act as pro-oxidants and sensitize human cancer cell lines to paclitaxel.Ana Podolski-Renić et al.Metallomics : integrated biometal science, 9(8), 1132-1141 (2017-07-25) Evaluation of hexane and ethyl acetate extracts of the sponge Jaspis diastra collected from Mauritius Waters on HeLa cells.Girish Beedessee et al.The Journal of pharmacy and pharmacology, 66(9), 1317-1327 (2014-04-25) Bioactivity Evaluation of a Novel Formulated Curcumin.Se-Chun Liao et al.Nutrients, 11(12) (2019-12-11) Attenuated SAG expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of H9c2 cardiomyocytes.J H Park et al.Free radical research, 49(8), 962-972 (2015-04-09) Cytotoxic effects of a chlorhexidine mouthwash and of an enzymatic mouthwash on human gingival fibroblasts.Ana Sofia Coelho et al.Odontology, 108(2), 260-270 (2019-10-19) Inhibition of TRIM32 Induced by miR-519d Increases the Sensitivity of Colorectal Cancer Cells to Cisplatin.Xueliang Su et al.OncoTargets and therapy, 13, 277-289 (2020-02-06) Dual function of IL-33 on proliferation of NIH-3T3 cells.Shin-Ichi Tominaga et al.Cytokine, 72(1), 105-108 (2015-01-13) Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production.J Reyes-Ocampo et al.Neurotoxicology, 50, 81-91 (2015-08-10) PINK1/Parkin-mediated mitophagy was activated against 1,4-Benzoquinone-induced apoptosis in HL-60 cells.Chunxiao Zhang et al.Toxicology in vitro : an international journal published in association with BIBRA, 50, 217-224 (2018-03-24) Effects of selection by the Percoll density gradient method on motility, mitochondrial membrane potential and fertility in a subpopulation of Atlantic salmon (Salmo salar) testicular spermatozoa.Williams Bravo et al.Animal reproduction science, 216, 106344-106344 (2020-05-18) Effects of Isatis root polysaccharide on boar sperm quality during liquid storage and in vitro fertilization.Zhiqiang Ren et al.Animal reproduction science, 210, 106178-106178 (2019-10-23) Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts.Mark J Pearson et al.Scientific reports, 8(1), 12887-12887 (2018-08-29) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria.Mahmoud S Sharaf et al.Aquatic toxicology (Amsterdam, Netherlands), 189, 170-183 (2017-06-25) Methamphetamine causes neurotoxicity by promoting polarization of macrophages and inflammatory response.X Li et al.Human & experimental toxicology, 37(5), 486-495 (2017-06-18) Control of stress-induced apoptosis by freezing tolerance-associated wheat proteins during cryopreservation of rat hepatocytes.Mélanie Chow-Shi-Yée et al.Cell stress & chaperones, 25(6), 869-886 (2020-06-13) Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.Yael Haberman et al.Nature communications, 10(1), 38-38 (2019-01-04) Cadmium inhibits the vitellogenesis of freshwater crab Sinopotamon henanense.Jian Yang et al.Environmental toxicology and chemistry, 34(7), 1609-1616 (2015-03-03) Nutrient values and bioactivities of the extracts from three fern species in China: a comparative assessment.Guoyuan Qi et al.Food & function, 6(9), 2918-2929 (2015-08-01) Irradiance plays a significant role in photobiomodulation of B16F10 melanoma cells by increasing reactive oxygen species and inhibiting mitochondrial function.Zeqing Chen et al.Biomedical optics express, 11(1), 27-39 (2020-02-06) Salvianolic acid A shows selective cytotoxicity against multidrug-resistant MCF-7 breast cancer cells.Xin Wang et al.Anti-cancer drugs, 26(2), 210-223 (2014-11-25) Evodiamine induces reactive oxygen species-dependent apoptosis and necroptosis in human melanoma A-375 cells.Ning Liu et al.Oncology letters, 20(4), 121-121 (2020-08-31) Interleukin-1β and tumor necrosis factor-α augment acidosis-induced rat articular chondrocyte apoptosis via nuclear factor-kappaB-dependent upregulation of ASIC1a channel.Ren-Peng Zhou et al.Biochimica et biophysica acta, 1864(1), 162-177 (2017-10-08) Cardioprotective effects of dihydroquercetin against ischemia reperfusion injury by inhibiting oxidative stress and endoplasmic reticulum stress-induced apoptosis via the PI3K/Akt pathway.Zunpeng Shu et al.Food & function, 10(1), 203-215 (2018-12-14) The protective effect of cordyceps sinensis extract on cerebral ischemic injury via modulating the mitochondrial respiratory chain and inhibiting the mitochondrial apoptotic pathway.Xue Bai et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 124, 109834-109834 (2020-01-25) Zn Supplement-Antagonized Cadmium-Induced Cytotoxicity in Macrophages In Vitro: Involvement of Cadmium Bioaccumulation and Metallothioneins Regulation.Ding Zhang et al.Journal of agricultural and food chemistry, 67(16), 4611-4622 (2019-04-04) Mechanistic study of mtROS-JNK-SOD2 signaling in bupivacaine-induced neuron oxidative stress.Zhongjie Liu et al.Aging, 12(13), 13463-13476 (2020-07-14) Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo.Debasmita Dutta et al.Scientific reports, 9(1), 11506-11506 (2019-08-10) Bioactive components and mechanisms of Chinese poplar propolis alleviates oxidized low-density lipoprotein-induced endothelial cells injury.Huasong Chang et al.BMC complementary and alternative medicine, 18(1), 142-142 (2018-05-05) 1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy.Barbara Kaproń et al.Journal of enzyme inhibition and medicinal chemistry, 35(1), 993-1002 (2020-04-08) Inhibition of the electron transport chain in propofol induced neurotoxicity in zebrafish embryos.Lin He et al.Neurotoxicology and teratology, 78, 106856-106856 (2020-01-11) Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma.Ying Shen et al.Frontiers in pharmacology, 11, 444-444 (2020-05-21) Synergistic enhancement of parasiticidal activity of amphotericin B using copaiba oil in nanoemulsified carrier for oral delivery: an approach for non-toxic chemotherapy.Pramod K Gupta et al.British journal of pharmacology, 172(14), 3596-3610 (2015-04-01) Thrombopoietin Protects Cardiomyocytes from Iron-Overload Induced Oxidative Stress and Mitochondrial Injury.Shing Chan et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(5), 2063-2071 (2015-07-24) Neurotoxic effects of aflatoxin B1 on human astrocytes in vitro and on glial cell development in zebrafish in vivo.Sunwoo Park et al.Journal of hazardous materials, 386, 121639-121639 (2019-12-04) Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90.Min Wang et al.Frontiers in pharmacology, 8, 353-353 (2017-06-24) Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity.Hong Lei et al.Oncology reports, 40(6), 3447-3457 (2018-10-03) Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.Wojciech Senkowski et al.Molecular cancer therapeutics, 14(6), 1504-1516 (2015-04-26) Fucoidan Induces Apoptosis of HT-29 Cells via the Activation of DR4 and Mitochondrial Pathway.Xu Bai et al.Marine drugs, 18(4) (2020-04-25) Expression of mitofusin 2 in human sperm and its relationship to sperm motility and cryoprotective potentials.Fang Fang et al.Experimental biology and medicine (Maywood, N.J.), 243(12), 963-969 (2018-07-31) SH003‑induced G1 phase cell cycle arrest induces apoptosis in HeLa cervical cancer cells.Kang Min Lee et al.Molecular medicine reports, 16(6), 8237-8244 (2017-09-26) Carbon Chain Length Modulates MDA-MB-231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl-Urea Fatty Acids.Michael Murray et al.ChemMedChem, 15(2), 247-255 (2019-11-28) Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.Irene H Heijink et al.American journal of respiratory cell and molecular biology, 52(5), 554-562 (2014-09-06) Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome.Chih-Yu Hsieh et al.Cells, 9(2) (2020-01-26) ITGB4 deficiency induces senescence of airway epithelial cells through p53 activation.Lin Yuan et al.The FEBS journal, 286(6), 1191-1203 (2019-01-13) Effects of fluorescent carbon dots from the baked lamb on energy and lipid metabolism.Lijuan Zhang et al.Food chemistry, 338, 127832-127832 (2020-08-21) Transfer of healthy fibroblast-derived mitochondria to HeLa ρ0 and SAS ρ0 cells recovers the proliferation capabilities of these cancer cells under conventional culture medium, but increase their sensitivity to cisplatin-induced apoptotic death.Amaneh Mohammadi Roushandeh et al.Molecular biology reports, 47(6), 4401-4411 (2020-05-13) Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.Jilong Zou et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(5), 1812-1821 (2017-07-28) Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.Daojuan Wang et al.Journal of translational medicine, 18(1), 84-84 (2020-02-19) Discovery of novel pyrazoline derivatives containing methyl-1H-indole moiety as potential inhibitors for blocking APC-Asef interactions.Peng-Fei Qi et al.Bioorganic chemistry, 99, 103838-103838 (2020-04-26) Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function.Jin-Huan Jiang et al.Pathology, research and practice, 214(5), 691-699 (2018-03-24) Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse.Gerardo Ramos-Mandujano et al.Stem cell research, 12(3), 690-702 (2014-04-01) The Combination of Glycolytic Inhibitor 2-Deoxyglucose and Microbubbles Increases the Effect of 5-Aminolevulinic Acid-Sonodynamic Therapy in Liver Cancer Cells.Rui Xie et al.Ultrasound in medicine & biology, 43(11), 2640-2650 (2017-08-28) Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway.Yanji Cui et al.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 23(2), 121-130 (2019-03-02) Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells.Ling Liu et al.Journal of experimental & clinical cancer research : CR, 37(1), 142-142 (2018-07-11) Neuroprotective Effects of an Aqueous Extract of Forsythia viridissima and Its Major Constituents on Oxaliplatin-Induced Peripheral Neuropathy.Jin-Mu Yi et al.Molecules (Basel, Switzerland), 24(6) (2019-04-03) Cytotoxic effects of a chlorhexidine mouthwash and of an enzymatic mouthwash on human gingival fibroblasts.Ana Sofia Coelho et al.Odontology, 108(2), 260-270 (2019-10-19) Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.Yael Haberman et al.Nature communications, 10(1), 38-38 (2019-01-04) Inhibition of TRIM32 Induced by miR-519d Increases the Sensitivity of Colorectal Cancer Cells to Cisplatin.Xueliang Su et al.OncoTargets and therapy, 13, 277-289 (2020-02-06) PINK1/Parkin-mediated mitophagy was activated against 1,4-Benzoquinone-induced apoptosis in HL-60 cells.Chunxiao Zhang et al.Toxicology in vitro : an international journal published in association with BIBRA, 50, 217-224 (2018-03-24) Effects of selection by the Percoll density gradient method on motility, mitochondrial membrane potential and fertility in a subpopulation of Atlantic salmon (Salmo salar) testicular spermatozoa.Williams Bravo et al.Animal reproduction science, 216, 106344-106344 (2020-05-18) Effects of Isatis root polysaccharide on boar sperm quality during liquid storage and in vitro fertilization.Zhiqiang Ren et al.Animal reproduction science, 210, 106178-106178 (2019-10-23) Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts.Mark J Pearson et al.Scientific reports, 8(1), 12887-12887 (2018-08-29) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria.Mahmoud S Sharaf et al.Aquatic toxicology (Amsterdam, Netherlands), 189, 170-183 (2017-06-25) Methamphetamine causes neurotoxicity by promoting polarization of macrophages and inflammatory response.X Li et al.Human & experimental toxicology, 37(5), 486-495 (2017-06-18) Control of stress-induced apoptosis by freezing tolerance-associated wheat proteins during cryopreservation of rat hepatocytes.Mélanie Chow-Shi-Yée et al.Cell stress & chaperones, 25(6), 869-886 (2020-06-13) Cadmium inhibits the vitellogenesis of freshwater crab Sinopotamon henanense.Jian Yang et al.Environmental toxicology and chemistry, 34(7), 1609-1616 (2015-03-03) Nutrient values and bioactivities of the extracts from three fern species in China: a comparative assessment.Guoyuan Qi et al.Food & function, 6(9), 2918-2929 (2015-08-01) Irradiance plays a significant role in photobiomodulation of B16F10 melanoma cells by increasing reactive oxygen species and inhibiting mitochondrial function.Zeqing Chen et al.Biomedical optics express, 11(1), 27-39 (2020-02-06) Oleic acid ameliorates adrenaline induced dysfunction of rat heart mitochondria by binding with adrenaline: An isothermal titration calorimetry study.Sanatan Mishra et al.Life sciences, 218, 96-111 (2018-12-24) Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo.Debasmita Dutta et al.Scientific reports, 9(1), 11506-11506 (2019-08-10) Bioactive components and mechanisms of Chinese poplar propolis alleviates oxidized low-density lipoprotein-induced endothelial cells injury.Huasong Chang et al.BMC complementary and alternative medicine, 18(1), 142-142 (2018-05-05) Salvianolic acid A shows selective cytotoxicity against multidrug-resistant MCF-7 breast cancer cells.Xin Wang et al.Anti-cancer drugs, 26(2), 210-223 (2014-11-25) Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma.Ying Shen et al.Frontiers in pharmacology, 11, 444-444 (2020-05-21) Dual function of IL-33 on proliferation of NIH-3T3 cells.Shin-Ichi Tominaga et al.Cytokine, 72(1), 105-108 (2015-01-13) Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production.J Reyes-Ocampo et al.Neurotoxicology, 50, 81-91 (2015-08-10) Cardioprotective effects of dihydroquercetin against ischemia reperfusion injury by inhibiting oxidative stress and endoplasmic reticulum stress-induced apoptosis via the PI3K/Akt pathway.Zunpeng Shu et al.Food & function, 10(1), 203-215 (2018-12-14) Synergistic enhancement of parasiticidal activity of amphotericin B using copaiba oil in nanoemulsified carrier for oral delivery: an approach for non-toxic chemotherapy.Pramod K Gupta et al.British journal of pharmacology, 172(14), 3596-3610 (2015-04-01) Thrombopoietin Protects Cardiomyocytes from Iron-Overload Induced Oxidative Stress and Mitochondrial Injury.Shing Chan et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(5), 2063-2071 (2015-07-24) Neurotoxic effects of aflatoxin B1 on human astrocytes in vitro and on glial cell development in zebrafish in vivo.Sunwoo Park et al.Journal of hazardous materials, 386, 121639-121639 (2019-12-04) Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90.Min Wang et al.Frontiers in pharmacology, 8, 353-353 (2017-06-24) Cytoplasm lipids can be modulated through hormone-sensitive lipase and are related to mitochondrial function in porcine IVM oocytes.Qingrui Zhuan et al.Reproduction, fertility, and development, 32(7), 667-675 (2020-03-17) Extraction, selenylation modification and antitumor activity of the glucan from Castanea mollissima Blume.Hongyan Li et al.Glycoconjugate journal, 34(2), 207-217 (2016-12-16) Exogenous HJichao Wu et al.Cell death & disease, 8(8), e2992-e2992 (2017-08-11) Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice.Yong Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 116, 108970-108970 (2019-05-20) Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy.Sitong Du et al.Theranostics, 9(7), 1878-1892 (2019-05-01) Etlingera elatior Extract promotes cell death in B16 melanoma cells via down-regulation of ERK and Akt signaling pathways.Aungkana Krajarng et al.BMC complementary and alternative medicine, 17(1), 415-415 (2017-08-24) Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis via enhancement of oxidative stress in human colorectal cancer SW620 cells.Yali Zhang et al.Oncology reports, 38(6), 3319-3326 (2017-10-19) Xihuang Pill Induces Apoptosis of Human Glioblastoma U-87 MG Cells via Targeting ROS-Mediated Akt/mTOR/FOXO1 Pathway.Meng Shao et al.Evidence-based complementary and alternative medicine : eCAM, 2018, 6049498-6049498 (2018-07-27) GLP-1 Receptor Agonist Exenatide Attenuates the Detrimental Effects of Obesity on Inflammatory Profile in Testis and Sperm Quality in Mice.Erhong Zhang et al.American journal of reproductive immunology (New York, N.Y. : 1989), 74(5), 457-466 (2015-08-20) Interferon regulatory factor 5 (IRF5) suppresses hepatitis C virus (HCV) replication and HCV-associated hepatocellular carcinoma.Ozge Cevik et al.The Journal of biological chemistry, 292(52), 21676-21689 (2017-10-29) Plasma membrane vesicles of human umbilical cord mesenchymal stem cells ameliorate acetaminophen-induced damage in HepG2 cells: a novel stem cell therapy.Mei-Jia Lin et al.Stem cell research & therapy, 11(1), 225-225 (2020-06-10) Carbon monoxide (CO) modulates hydrogen peroxide (H2O2)-mediated cellular dysfunction by targeting mitochondria in rabbit lens epithelial cells.Yang Huang et al.Experimental eye research, 169, 68-78 (2018-02-07) Salinomycin induces autophagic cell death in salinomycin-sensitive melanoma cells through inhibition of autophagic flux.Yajing Liu et al.Scientific reports, 10(1), 18515-18515 (2020-10-30) Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression.Weimei Ruan et al.Oncogene, 38(22), 4352-4365 (2019-02-17) The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation.Rui-Qi Wang et al.Cancer cell international, 19, 145-145 (2019-05-30) Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.Jiaxin Liu et al.Acta biochimica et biophysica Sinica, 49(6), 479-486 (2017-04-28) ROS generation and autophagosome accumulation contribute to the DMAMCL-induced inhibition of glioma cell proliferation by regulating the ROS/MAPK signaling pathway and suppressing the Akt/mTOR signaling pathway.Yanjun Wang et al.OncoTargets and therapy, 12, 1867-1880 (2019-03-19) Structural characterization and cardioprotective activity of a novel polysaccharide from Fructus aurantii.Zunpeng Shu et al.International journal of biological macromolecules, 144, 847-856 (2019-11-13) In vitro antifungal activity of baicalin against Candida albicans biofilms via apoptotic induction.TianMing Wang et al.Microbial pathogenesis, 87, 21-29 (2015-07-15) Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function inFeng-Juan Gao et al.Frontiers in molecular neuroscience, 10, 285-285 (2017-09-25) AKT mediated glycolytic shift regulates autophagy in classically activated macrophages.Sumit Kumar Matta et al.The international journal of biochemistry & cell biology, 66, 121-133 (2015-07-30) ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury.Hui Yu et al.Theranostics, 10(5), 2342-2357 (2020-02-28) Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes.Yi Li et al.Journal of inorganic biochemistry, 205, 110976-110976 (2020-01-12) Ebselen protects mitochondrial function and oxidative stress while inhibiting the mitochondrial apoptosis pathway after acute spinal cord injury.Zhi-Qiang Jia et al.Neuroscience letters, 678, 110-117 (2018-05-08) Two new flavonoid-triterpene saponin meroterpenoids from Clinopodium chinense and their protective effects against anoxia/reoxygenation-induced apoptosis in H9c2 cells.Yin-Di Zhu et al.Fitoterapia, 128, 180-186 (2018-05-22) Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling.E Litwa et al.The Journal of steroid biochemistry and molecular biology, 144 Pt B, 334-347 (2014-08-06) 6-Formyl-5-isopropyl-3-hydroxymethyl- 7-methyl-1H-indene mitigates methamphetamine-induced photoreceptor cell toxicity through inhibiting oxidative stress.H Xu et al.Human & experimental toxicology, 39(5), 712-720 (2020-01-14) Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells.Seyma Aydinlik et al.Biochimica et biophysica acta. General subjects, 1863(5), 903-916 (2019-03-03) Carbon nanotube filler enhances incinerated thermoplastics-induced cytotoxicity and metabolic disruption in vitro.Jayme P Coyle et al.Particle and fibre toxicology, 17(1), 40-40 (2020-08-14) Nitration of Hsp90 on Tyrosine 33 Regulates Mitochondrial Metabolism.Maria C Franco et al.The Journal of biological chemistry, 290(31), 19055-19066 (2015-06-19) Cannabidiol induced apoptosis in human monocytes through mitochondrial permeability transition pore-mediated ROS production.Hsin-Ying Wu et al.Free radical biology & medicine, 124, 311-318 (2018-06-26) In vivo hepatocellular expression of interleukin-22 using penetratin-based hybrid nanoparticles as potential anti-hepatitis therapeutics.Wei Chen et al.Biomaterials, 187, 66-80 (2018-10-09) Mitofusin-2-mediated tethering of mitochondria and endoplasmic reticulum promotes cell cycle arrest of vascular smooth muscle cells in G0/G1 phase.Dan Li et al.Acta biochimica et biophysica Sinica, 47(6), 441-450 (2015-05-01) Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes.Maria Ylenia Farrugia et al.Scientific reports, 10(1), 17733-17733 (2020-10-22) pH-sensitive micelles for the intracellular co-delivery of curcumin and Pluronic L61 unimers for synergistic reversal effect of multidrug resistance.Wei Hong et al.Scientific reports, 7, 42465-42465 (2017-02-15) Aegeline inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance.Sujith Rajan et al.Metabolism: clinical and experimental, 85, 1-13 (2018-03-11) Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression.Dandan Yu et al.Acta biochimica et biophysica Sinica, 50(8), 782-792 (2018-07-03) Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors.Ai-ting Wang et al.Biomaterials, 53, 160-172 (2015-04-22) The effect of resveratrol, its naturally occurring derivatives and tannic acid on the induction of cell cycle arrest and apoptosis in rat C6 and human T98G glioma cell lines.Małgorzata Zielińska-Przyjemska et al.Toxicology in vitro : an international journal published in association with BIBRA, 43, 69-75 (2017-06-10) Mesenchymal stem cell conditioned medium alleviates oxidative stress injury induced by hydrogen peroxide via regulating miR143 and its target protein in hepatocytes.Xuejing Xu et al.BMC immunology, 18(1), 51-51 (2017-12-21) Released Mitochondrial DNA Following Intestinal Ischemia Reperfusion Induces the Inflammatory Response and Gut Barrier Dysfunction.Qiongyuan Hu et al.Scientific reports, 8(1), 7350-7350 (2018-05-11) Cardiac molecular pathways influenced by doxorubicin treatment in mice.Ben F Bulten et al.Scientific reports, 9(1), 2514-2514 (2019-02-23) Melatonin attenuates postovulatory oocyte dysfunction by regulating SIRT1 expression.Qingling Yang et al.Reproduction (Cambridge, England), 156(1), 81-92 (2018-05-13) AβPP-induced UPR Transcriptomic Signature of Glial Cells to Oxidative Stress as an Adaptive Mechanism to Preserve Cell Function and Survival.Naima Chalour et al.Current Alzheimer research, 15(7), 643-654 (2018-01-24) Protective effects of apigenin against 1-methyl-4-phenylpyridinium ion‑induced neurotoxicity in PC12 cells.Weihai Liu et al.International journal of molecular medicine, 35(3), 739-746 (2015-01-13) High oxygen partial pressure increases photodynamic effect on HeLa cell lines in the presence of chloraluminium phthalocyanine.Robert Bajgar et al.Anticancer research, 34(8), 4095-4099 (2014-07-31) New cycloartane type-triterpenoids from the areal parts of Caragana sukiensis and their biological activities.S Divya Reddy et al.European journal of medicinal chemistry, 136, 74-84 (2017-05-10) Tetramethylpyrazine Attenuates the Endotheliotoxicity and the Mitochondrial Dysfunction by Doxorubicin via 14-3-3γ/Bcl-2.Bin Yang et al.Oxidative medicine and cellular longevity, 2019, 5820415-5820415 (2019-12-31) 1,2-Dichloroethane induces cerebellum granular cell apoptosis via mitochondrial pathway in vitro and in vivo.Manqi Huang et al.Toxicology letters, 322, 87-97 (2020-01-15) Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells.Kristina Shilnikova et al.Oncology letters, 15(4), 5417-5424 (2018-03-23) PACS2 is required for ox-LDL-induced endothelial cell apoptosis by regulating mitochondria-associated ER membrane formation and mitochondrial Ca2+ elevation.Sanjiu Yu et al.Experimental cell research, 379(2), 191-202 (2019-04-11) AMPK-SIRT1-PGC1α Signal Pathway Influences the Cognitive Function of Aged Rats in Sevoflurane-Induced Anesthesia.Xiao-Yu Yang et al.Journal of molecular neuroscience : MN, 70(12), 2058-2067 (2020-06-10) Quantitative Proteomics of Presynaptic Mitochondria Reveal an Overexpression and Biological Relevance of Neuronal MitoNEET in Postnatal Brain Development.Kelly L Stauch et al.Developmental neurobiology, 79(4), 370-386 (2019-05-03) Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers.Chiara Calorio et al.The Journal of physiology, 597(6), 1705-1733 (2019-01-11) Fucoidan Inhibition of Osteosarcoma Cells Is Species and Molecular Weight Dependent.Dhanak Gupta et al.Marine drugs, 18(2) (2020-02-13) Drug resistance reversal in ovarian cancer cells of paclitaxel and borneol combination therapy mediated by PEG-PAMAM nanoparticles.Liang Zou et al.Oncotarget, 8(36), 60453-60468 (2017-09-28) Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.Haifeng Zhang et al.Experimental cell research, 393(2), 112089-112089 (2020-05-23) Upregulation of mitochondrial E3 ubiquitin ligase 1 in rat heart contributes to ischemia/reperfusion injury.Shi-Jing Wang et al.Canadian journal of physiology and pharmacology, 98(5), 259-266 (2019-12-12) Bortezomib-Induced Muscle Toxicity in Multiple Myeloma.Valeria Guglielmi et al.Journal of neuropathology and experimental neurology, 76(7), 620-630 (2017-09-03) Reactive oxygen species-dependent apoptosis induction by water extract of Citrus unshiu peel in MDA-MB-231 human breast carcinoma cells.Min Yeong Kim et al.Nutrition research and practice, 12(2), 129-134 (2018-04-10) Intrahepatic Delivery of Pegylated Catalase Is Protective in a Rat Ischemia/Reperfusion Injury Model.Clifford Akateh et al.The Journal of surgical research, 238, 152-163 (2019-02-17) Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.Amara Maryam et al.Oxidative medicine and cellular longevity, 2018, 3853409-3853409 (2018-03-27) Sestrin‑2 regulates podocyte mitochondrial dysfunction and apoptosis under high‑glucose conditions via AMPK.Qiaoxuan Lin et al.International journal of molecular medicine, 45(5), 1361-1372 (2020-04-24) Growth Hormone Receptor Gene is Essential for Chicken Mitochondrial Function In Vivo and In Vitro.Bowen Hu et al.International journal of molecular sciences, 20(7) (2019-04-03) Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.Yanyan Wang et al.International immunopharmacology, 73, 471-481 (2019-06-07) Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury.Jihoon Nah et al.The Journal of clinical investigation, 130(6), 2978-2991 (2020-05-05) Effect of post-thaw supplementation of fractionated seminal plasma on survival of boar spermatozoa.K Wasilewska-Sakowska et al.Polish journal of veterinary sciences, 22(3), 617-625 (2019-09-29) Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma.A C Mamede et al.Medical oncology (Northwood, London, England), 32(12), 257-257 (2015-10-29) Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of peroxiredoxins.B Fiuza et al.Free radical research, 49(2), 122-132 (2014-11-07) PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.Xudong Yao et al.Stem cell research & therapy, 11(1), 140-140 (2020-04-02) Selective phenylalanine to proline substitution for improved antimicrobial and anticancer activities of peptides designed on phenylalanine heptad repeat.Amit Kumar Tripathi et al.Acta biomaterialia, 57, 170-186 (2017-05-10) Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.Liwei Wu et al.British journal of pharmacology, 177(16), 3760-3777 (2020-05-24) Chicoric acid mitigates impaired insulin sensitivity by improving mitochondrial function.Ji-Sun Kim et al.Bioscience, biotechnology, and biochemistry, 82(7), 1197-1206 (2018-03-21) Astragaloside IV Protects Ethanol-Induced Gastric Mucosal Injury by Preventing Mitochondrial Oxidative Stress and the Activation of Mitochondrial Pathway Apoptosis in Rats.Shumin Qin et al.Frontiers in pharmacology, 10, 894-894 (2019-09-03) Melatonin protects hepatocytes against bile acid-induced mitochondrial oxidative stress via the AMPK-SIRT3-SOD2 pathway.Y Chen et al.Free radical research, 49(10), 1275-1284 (2015-06-30) Effect of inhibin A on proliferation of porcine granulosa cells in vitro.Wanhong Li et al.Theriogenology, 114, 136-142 (2018-04-04) Xun Zhou et al.International journal of molecular sciences, 21(8) (2020-04-25)Halogenation of amphetamines and methcathinones has become a common method to obtain novel psychoactive substances (NPS) also called "legal highs". The para-halogenated derivatives of amphetamine and methcathinone are available over the internet and have entered the illicit drug market but... YAN, a novel microtubule inhibitor, inhibits P-gp and MRP1 function and induces mitotic slippage followed by apoptosis in multidrug-resistant A549/Taxol cells.Minghuan Gao et al.Toxicology in vitro : an international journal published in association with BIBRA, 69, 104971-104971 (2020-08-18) Baicalein Protects against Rotenone-Induced Neurotoxicity through Induction of Autophagy.Lianghong Kuang et al.Biological & pharmaceutical bulletin, 40(9), 1537-1543 (2017-07-01) LncRNA-Malat1 is Involved in Lipotoxicity-Induced ß-cell Dysfunction and the Therapeutic Effect of Exendin-4 via Ptbp1.Li Xiong et al.Endocrinology, 161(7) (2020-04-24) Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretionLi L Cell Death & Disease (2016) Dimeric and tetrameric forms of muscle fructose-1,6-bisphosphatase play different roles in the cell.Janusz Wiśniewski et al.Oncotarget, 8(70), 115420-115433 (2018-02-01) Synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents.Xiaochao Huang et al.European journal of medicinal chemistry, 132, 11-25 (2017-03-25) Dexmedetomidine Protects Against Chemical Hypoxia-Induced Neurotoxicity in Differentiated PC12 Cells Via Inhibition of NADPH Oxidase 2-Mediated Oxidative Stress.Xiao-Hui Chen et al.Neurotoxicity research, 35(1), 139-149 (2018-08-17) Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia.Jan Ježek et al.Frontiers in endocrinology, 9, 637-637 (2018-11-13) Obesity-exposed oocytes accumulate and transmit damaged mitochondria due to an inability to activate mitophagy.Anna L Boudoures et al.Developmental biology, 426(1), 126-138 (2017-04-26) Inhibition of VDAC1 prevents Ca²⁺-mediated oxidative stress and apoptosis induced by 5-aminolevulinic acid mediated sonodynamic therapy in THP-1 macrophages.Haibo Chen et al.Apoptosis : an international journal on programmed cell death, 19(12), 1712-1726 (2014-10-25) Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis.Binwu Hu et al.Frontiers in cell and developmental biology, 8, 685-685 (2020-08-28) Abyssinone V-4' Methyl Ether, a Flavanone Isolated from Erythrina droogmansiana, Exhibits Cytotoxic Effects on Human Breast Cancer Cells by Induction of Apoptosis and Suppression of Invasion.Stéphane Zingue et al.Evidence-based complementary and alternative medicine : eCAM, 2020, 6454853-6454853 (2020-08-11) Protection of miR-19b in hypoxia/reoxygenation-induced injury by targeting PTEN.Wan-Gen Liu et al.Journal of cellular physiology (2019-02-16) Effects of Brain-Derived Mitochondria on the Function of Neuron and Vascular Endothelial Cell After Traumatic Brain Injury.Baoliang Zhang et al.World neurosurgery, 138, e1-e9 (2019-12-10) FOXP1-induced lncRNA CLRN1-AS1 acts as a tumor suppressor in pituitary prolactinoma by repressing the autophagy via inactivating Wnt/β-catenin signaling pathway.Chao Wang et al.Cell death & disease, 10(7), 499-499 (2019-06-27) Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness.Mayumi Fujita et al.BMC cancer, 20(1), 929-929 (2020-10-01) Lotus Seedpod Extracts Reduced Lipid Accumulation and Lipotoxicity in Hepatocytes.Yen-Tze Liu et al.Nutrients, 11(12) (2019-12-05) Dynamin 3 suppresses growth and induces apoptosis of hepatocellular carcinoma cells by activating inducible nitric oxide synthase production.Chao Gu et al.Oncology letters, 13(6), 4776-4784 (2017-06-11) p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke.Ming Zhang et al.Oxidative medicine and cellular longevity, 2018, 5837123-5837123 (2018-06-01) Epoxycytochalasin H: An Endophytic Phomopsis Compound Induces Apoptosis in A2780 Cells Through Mitochondrial Damage and Endoplasmic Reticulum Stress.Jiabin Wang et al.OncoTargets and therapy, 13, 4987-4997 (2020-06-26) Protective effects of apigenin against 3-MCPD-induced renal injury in rat.Yujie Zhong et al.Chemico-biological interactions, 296, 9-17 (2018-08-15) Design and Synthesis of Molecular Hybrids of Sophora Alkaloids and Cinnamic Acids as Potential Antitumor Agents.Hai Shang et al.Molecules (Basel, Switzerland), 25(5) (2020-03-11) Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer.Venkatesh Pooladanda et al.Toxicology in vitro : an international journal published in association with BIBRA, 51, 114-128 (2018-05-21) T-2 Toxin-Induced Oxidative Stress Leads to Imbalance of Mitochondrial Fission and Fusion to Activate Cellular Apoptosis in the Human Liver 7702 Cell Line.Junhua Yang et al.Toxins, 12(1) (2020-01-16) Oridonin induces the apoptosis of mucoepidermoid carcinoma cell lines in a myeloid cell leukemia‑1‑dependent manner.Jung-Min Han et al.International journal of oncology, 57(1), 377-385 (2020-05-30) Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.Zengxian Sun et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 115, 108933-108933 (2019-05-07) OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway.Xiaolong Yu et al.Chemosphere, 221, 693-702 (2019-01-23) In Vitro and In Vivo Evaluation of Antitumor Activity of Ligustrum robustum, A Chinese Herbal Tea.Hao-Jiang Zuo et al.Chinese journal of integrative medicine, 25(6), 425-430 (2018-05-24) NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis.Wei Zhao et al.Scientific reports, 10(1), 3078-3078 (2020-02-23) Mono-(2-ethylhexyl) phthalate induced ROS-dependent autophagic cell death in human vascular endothelial cells.Nairong Liu et al.Toxicology in vitro : an international journal published in association with BIBRA, 44, 49-56 (2017-06-29) Troxerutin, a plant flavonoid, protects cells against oxidative stress-induced cell death through radical scavenging mechanism.Niranjan A Panat et al.Food chemistry, 194, 32-45 (2015-10-17) Proanthocyanidins Ameliorated Deficits of Lipid Metabolism in Type 2 Diabetes Mellitus Via Inhibiting Adipogenesis and Improving Mitochondrial Function.Fangfang Tie et al.International journal of molecular sciences, 21(6) (2020-03-20) Therapeutic potential of ReACp53 targeting mutant p53 protein in CRPC.Yaqun Zhang et al.Prostate cancer and prostatic diseases, 23(1), 160-171 (2019-09-01) Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis via inhibition of mitochondrial‑derived oxidative stress.Yujie Liu et al.Molecular medicine reports, 15(5), 2457-2464 (2017-04-28) New ruthenium compounds bearing semicarbazone 2-formylopyridine moiety: Playing with auxiliary ligands for tuning the mechanism of biological activity.Michał Łomzik et al.Journal of inorganic biochemistry, 175, 80-91 (2017-07-25) Protective effects of zinc and N-acetyl-L-cysteine supplementation against cadmium induced erythrocyte cytotoxicity in Arbor Acres broiler chickens (Gallus gallus domesticus).Ding Zhang et al.Ecotoxicology and environmental safety, 163, 331-339 (2018-07-31) Cinobufagin induces cell cycle arrest at the S phase and promotes apoptosis in nasopharyngeal carcinoma cells.Zhaohai Pan et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 122, 109763-109763 (2020-01-10) Role of zinc trafficking in male fertility: from germ to sperm.Carlo Foresta et al.Human reproduction (Oxford, England), 29(6), 1134-1145 (2014-04-29) Mitochondrion-Mediated Apoptosis Induced by Acrylamide is Regulated by a Balance Between Nrf2 Antioxidant and MAPK Signaling Pathways in PC12 Cells.Xiaoqi Pan et al.Molecular neurobiology, 54(6), 4781-4794 (2016-08-10) Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways.Sayilaxi Jieensinue et al.BMC cell biology, 19(1), 21-21 (2018-09-27) Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.Veronica R Placencio et al.PloS one, 10(7), e0133786-e0133786 (2015-07-25) Betaine is a positive regulator of mitochondrial respiration.Icksoo Lee Biochemical and biophysical research communications, 456(2), 621-625 (2014-12-17) Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening.Ahmed Elkamhawy et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 104, 366-381 (2017-04-25) Vancomycin induces reactive oxygen species-dependent apoptosis via mitochondrial cardiolipin peroxidation in renal tubular epithelial cells.Yuya Sakamoto et al.European journal of pharmacology, 800, 48-56 (2017-02-22) SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo.Xiuli Yi et al.Theranostics, 9(6), 1614-1633 (2019-05-01) Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wnt/β-catenin signaling pathways.Anna Xiao-Dan Yu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4311-4328 (2020-01-23) Oligostilbenes extracts from Iris lactea Pall. var. chinensis (Fisch.) Koidz improve lipid metabolism in HFD/STZ-induced diabetic mice and inhibit adipogenesis in 3T3-L1 cells.Fangfang Tie et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 131, 110800-110800 (2020-11-07) Induction of Apoptosis and Reduction of Endogenous Glutathione Level by the Ethyl-Acetate Soluble Fraction of the Methanol Extract of the Roots of Potentilla fulgens in Cancer Cells.Debabrata Tripathy et al.PloS one, 10(8), e0135890-e0135890 (2015-08-19) The Effect of Velvet Antler Proteins on Cardiac Microvascular Endothelial Cells Challenged with Ischemia-Hypoxia.Xiang Xiao et al.Frontiers in pharmacology, 8, 601-601 (2017-09-25) Induction of Apoptosis in HepaRG Cell Line by Aloe-Emodin through Generation of Reactive Oxygen Species and the Mitochondrial Pathway.Xiaoxv Dong et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(2), 685-696 (2017-06-16) Cryoprotective effect of melatonin supplementation on post-thawed rooster sperm quality.Gamal M K Mehaisen et al.Animal reproduction science, 212, 106238-106238 (2019-12-23) Effect of magnesium on reducing the UV-induced oxidative damage in marrow mesenchymal stem cells.Yangmei Chen et al.Journal of biomedical materials research. Part A, 107(6), 1253-1263 (2019-02-01) Resveratrol prevents nanoparticles-induced inflammation and oxidative stress via downregulation of PKC-α and NADPH oxidase in lung epithelial A549 cells.Hung-Te Hsu et al.BMC complementary and alternative medicine, 18(1), 211-211 (2018-07-11) Sitagliptin ameliorates renal tubular injury in diabetic kidney disease via STAT3-dependent mitochondrial homeostasis through SDF-1α/CXCR4 pathway.Qunzi Zhang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(6), 7500-7519 (2020-04-14) Defeating relapsed and refractory malignancies through a nano-enabled mitochondria-mediated respiratory inhibition and damage pathway.Zhengyang Yang et al.Biomaterials, 229, 119580-119580 (2019-11-11) Molecular Hydrogen Protects Human Melanocytes from Oxidative Stress by Activating Nrf2 Signaling.Wei Fang et al.The Journal of investigative dermatology, 140(11), 2230-2241 (2020-04-03) In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin.Miriam Durante et al.European journal of pharmacology, 880, 173164-173164 (2020-05-22) Transmembrane protein 126B protects against high fat diet (HFD)-induced renal injury by suppressing dyslipidemia via inhibition of ROS.Chen Weihong et al.Biochemical and biophysical research communications, 509(1), 40-47 (2018-12-26) Mitochondrial characteristics contribute to proliferation and migration potency of MDA-MB-231 cancer cells and their response to cisplatin treatment.Mojdeh Kheirandish-Rostami et al.Life sciences, 244, 117339-117339 (2020-01-24) Overexpression of miR-216b sensitizes NSCLC cells to cisplatin-induced apoptosis by targeting c-Jun.Gang Huang et al.Oncotarget, 8(61), 104206-104215 (2017-12-22) Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation.Shuo Zhang et al.Neural regeneration research, 15(11), 2143-2153 (2020-05-13) Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein.Wenjia Ma et al.Aging, 11(9), 2670-2680 (2019-05-06) Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex.Rui Zhang et al.Oncotarget, 8(28), 45213-45223 (2017-04-20) Activation of Cannabinoid Receptors Attenuates Endothelin-1-Induced Mitochondrial Dysfunction in Rat Ventricular Myocytes.Yan Lu et al.Journal of cardiovascular pharmacology, 75(1), 54-63 (2019-12-10) Resveratrol Prevents Acrylamide-Induced Mitochondrial Dysfunction and Inflammatory Responses via Targeting Circadian Regulator Bmal1 and Cry1 in Hepatocytes.Xintong Tan et al.Journal of agricultural and food chemistry, 67(31), 8510-8519 (2019-07-12) Pheretima aspergillum extract attenuates high-KCl-induced mitochondrial injury and pro-fibrotic events in cardiomyoblast cells.Pei-Chen Huang et al.Environmental toxicology, 34(8), 921-927 (2019-05-09) Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury.Chaojin Chen et al.Antioxidants & redox signaling (2018-05-24) Antioxidant activity and anticancer effect of ethanolic and aqueous extracts of the roots of Ficus beecheyana and their phenolic components.Gow-Chin Yen et al.Journal of food and drug analysis, 26(1), 182-192 (2018-02-02) Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer.Mousumi Bhattacharjee et al.Biochimica et biophysica acta. General subjects, 1864(11), 129695-129695 (2020-08-01) H2 O2 induces PP2A demethylation to downregulate mTORC1 signaling in HEK293 cells.Shen Tang et al.Cell biology international (2018-05-13) Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission.Zhuyun Chen et al.Oncotarget, 8(51), 88792-88803 (2017-11-29) Alpha7 nicotinic acetylcholine receptor activation protects against myocardial reperfusion injury through modulation of autophagy.Zuoxu Hou et al.Biochemical and biophysical research communications, 500(2), 357-364 (2018-04-18) Aggregation is impaired in starved platelets due to enhanced autophagy and cellular energy depletion.Manoj Paul et al.Platelets, 30(4), 487-497 (2018-05-26) Melatonin alleviates defects induced by zearalenone during porcine embryo development.Xuerui Yao et al.Theriogenology, 151, 66-73 (2020-04-21) RETRACTED: Bovine Herpesvirus 5 promotes mitochondrial dysfunction in cultured bovine monocyte-derived macrophages and not affect virus replication.Tereza C Cardoso et al.Veterinary microbiology, 229, 153-158 (2019-01-16) Alpinoid c analog inhibits angiogenesis and induces apoptosis in COLO205 cell line.Loka Reddy Velatooru et al.Chemico-biological interactions, 308, 1-10 (2019-05-10) CypD deficiency confers neuroprotection against mitochondrial abnormality caused by lead in SH-SY5Y cell.Fang Ye et al.Toxicology letters, 323, 25-34 (2019-12-25) Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) components against pathogenic fungi.Xia Da et al.Scientific reports, 9(1), 1683-1683 (2019-02-10) Evaluating the Efficacy of Taurodeoxycholic Acid in Providing Otoprotection Using an in vitro Model of Electrode Insertion Trauma.Viraj Shah et al.Frontiers in molecular neuroscience, 13, 113-113 (2020-08-08) Activation of NaXiaofei Yan et al.Apoptosis : an international journal on programmed cell death, 22(4), 531-543 (2017-02-10) Pharmacological Basis for the Use of Evodiamine in Alzheimer's Disease: Antioxidation and Antiapoptosis.Yongfeng Zhang et al.International journal of molecular sciences, 19(5) (2018-06-09) Nicotine-induced cellular stresses and autophagy in human cancer colon cells: A supportive effect on cell homeostasis via up-regulation of Cox-2 and PGE(2) production.Marjolaine A Pelissier-Rota et al.The international journal of biochemistry & cell biology, 65, 239-256 (2015-06-24) Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway.Yi Liu et al.Toxins, 10(5) (2018-05-16) A hybrid platinum drug dichloroacetate-platinum(II) overcomes cisplatin drug resistance through dual organelle targeting.Yu Zhang et al.Anti-cancer drugs, 26(7), 698-705 (2015-03-27) Mitochondria P-glycoprotein confers paclitaxel resistance on ovarian cancer cells.Weina Guo et al.OncoTargets and therapy, 12, 3881-3891 (2019-06-14) Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study.H-Y Li et al.Cell death & disease, 6, e1604-e1604 (2015-01-23) Effects of the Emitted Light Spectrum of Liquid Crystal Displays on Light-Induced Retinal Photoreceptor Cell Damage.Chao-Wen Lin et al.International journal of molecular sciences, 20(9) (2019-05-15) JNK1 and JNK3 play a significant role in both neuronal apoptosis and necrosis. Evaluation based on in vitro approach using tert-butylhydroperoxide induced oxidative stress in neuro-2A cells and perturbation through 3-aminobenzamide.Vijaya Prakash Krishnan Muthaiah et al.Toxicology in vitro : an international journal published in association with BIBRA, 41, 168-178 (2017-03-05) Synthesis and antibacterial activity of iron-hexacyanocobaltate nanoparticles.Michela Ciabocco et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 23(3), 385-398 (2018-02-27) Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway.Yu Li et al.Frontiers in cell and developmental biology, 8, 245-245 (2020-05-16) MicroRNA‑138 promotes proliferation and suppresses mitochondrial depolarization in human pulmonary artery smooth muscle cells through targeting TASK‑1.Jin-Jun Liu et al.Molecular medicine reports, 17(2), 3021-3027 (2017-12-20) N-Acetyl Cysteine (NAC)-Directed Detoxification of Methacryloxylethyl Cetyl Ammonium Chloride (DMAE-CB).Yang Jiao et al.PloS one, 10(8), e0135815-e0135815 (2015-08-15) Aloe-emodin induces hepatotoxicity by the inhibition of multidrug resistance protein 2.De-Ming Liu et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 68, 153148-153148 (2020-02-07) Sodium hydrosulfide attenuates hyperhomocysteinemia rat myocardial injury through cardiac mitochondrial protection.Yuwen Wang et al.Molecular and cellular biochemistry, 399(1-2), 189-200 (2014-11-08) Baicalin inhibits C2C12 myoblast apoptosis and prevents against skeletal muscle injury.Yutao Pan et al.Molecular medicine reports, 20(1), 709-718 (2019-06-11) Resveratrol prevents ammonia-induced mitochondrial dysfunction and cellular redox imbalance in C6 astroglial cells.Larissa Daniele Bobermin et al.Nutritional neuroscience, 21(4), 276-285 (2017-02-07) Apoptosis inhibition of Atlantic salmon (Salmo salar) peritoneal macrophages by Piscirickettsia salmonis.S Díaz et al.Journal of fish diseases, 40(12), 1895-1902 (2017-07-13) Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts.Yang Wang et al.Journal of experimental & clinical cancer research : CR, 37(1), 251-251 (2018-10-18) Cytotoxicity induced by carbon nanotubes in experimental malignant glioma.Samuel Romano-Feinholz et al.International journal of nanomedicine, 12, 6005-6026 (2017-09-02) Stephanthraniline A suppresses proliferation of HCT116 human colon cancer cells through induction of caspase-dependent apoptosis, dysregulation of mitochondrial function, cell cycle arrest and regulation of Akt/p38 signaling pathways.Lu Wang et al.The Journal of toxicological sciences, 44(8), 523-533 (2019-08-06) Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats.Jiayu Diao et al.Journal of physiology and biochemistry, 75(1), 39-51 (2018-09-19) Curcumin ameliorates oxidative stress-induced intestinal barrier injury and mitochondrial damage by promoting Parkin dependent mitophagy through AMPK-TFEB signal pathway.Shuting Cao et al.Free radical biology & medicine, 147, 8-22 (2019-12-10) Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation.Tadahide Furuno et al.Molecular and cellular biochemistry, 410(1-2), 215-221 (2015-09-10) GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump.Georg Schneditz et al.Science signaling, 12(562) (2019-01-03) Eckol Inhibits Particulate Matter 2.5-Induced Skin Keratinocyte Damage via MAPK Signaling Pathway.Ao Xuan Zhen et al.Marine drugs, 17(8) (2019-07-31) Tetramethylpyrazine attenuates lipopolysaccharide-induced cardiomyocyte injury via improving mitochondrial function mediated by 14-3-3γ.Bowei Huang et al.European journal of pharmacology, 832, 67-74 (2018-05-22) MiR-122-5p increases radiosensitivity and aggravates radiation-induced rectal injury through CCAR1.Yulong Ge et al.Toxicology and applied pharmacology, 399, 115054-115054 (2020-05-19) Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate.Jiandong Sun et al.Toxicology and applied pharmacology, 378, 114612-114612 (2019-06-09) Isosteviol Protects Free Fatty Acid- and High Fat Diet-Induced Hepatic Injury via Modulating PKC-β/p66Shc/ROS and Endoplasmic Reticulum Stress Pathways.Hongwei Yi et al.Antioxidants & redox signaling, 30(17), 1949-1968 (2018-11-30) Oxygen glucose deprivation/re-oxygenation-induced neuronal cell death is associated with Lnc-D63785 m6A methylation and miR-422a accumulation.Shu Xu et al.Cell death & disease, 11(9), 816-816 (2020-10-02) Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes.Zhe Gao et al.Biochemical pharmacology, 92(2), 358-368 (2014-09-15) Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.Delu Dong et al.Life sciences, 255, 117846-117846 (2020-05-30) N-benzyl-N-methyldecan-1-amine, a phenylamine derivative isolated from garlic cloves, induces G2/M phase arrest and apoptosis in U937 human leukemia cells.Jin-Woo Jeong et al.Oncology reports, 32(1), 373-381 (2014-05-27) The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy.Dongwei Xu et al.Cell death & disease, 8(8), e2983-e2983 (2017-08-11) Anticancer Effect of Mountain Ginseng on Human Breast Cancer: Comparison with Farm-Cultivated Ginseng.Jungeun Kim et al.Evidence-based complementary and alternative medicine : eCAM, 2020, 2584783-2584783 (2020-08-11) Targets Fishing and Identification of Calenduloside E as Hsp90AB1: Design, Synthesis, and Evaluation of Clickable Activity-Based Probe.Shan Wang et al.Frontiers in pharmacology, 9, 532-532 (2018-06-08) 2-Deoxy-Rh2: A novel ginsenoside derivative, as dual-targeting anti-cancer agent via regulating apoptosis and glycolysis.Huan Gao et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 124, 109891-109891 (2020-01-29) Overexpression of miR-101 promotes TRAIL-induced mitochondrial apoptosis in papillary thyroid carcinoma by targeting c-met and MCL-1.Jie Zhu et al.Oncotarget, 8(65), 108665-108675 (2018-01-10) Human Sialic acid O-acetyl esterase (SIAE) - mediated changes in sensitivity to etoposide in a medulloblastoma cell line.Rebecca L Mather et al.Scientific reports, 9(1), 8609-8609 (2019-06-15) Non-Benzoquinone Geldanamycin Analog, WK-88-1, Induces Apoptosis in Human Breast Cancer Cell Lines.Yu-Ru Zhao et al.Journal of microbiology and biotechnology, 28(4), 542-550 (2018-04-06) Exosome-Mediated Transfer of ACE2 (Angiotensin-Converting Enzyme 2) from Endothelial Progenitor Cells Promotes Survival and Function of Endothelial Cell.Jinju Wang et al.Oxidative medicine and cellular longevity, 2020, 4213541-4213541 (2020-02-14) Diallyl trisulfide induces apoptosis and mitotic arrest in AGS human gastric carcinoma cells through reactive oxygen species-mediated activation of AMP-activated protein kinase.Yung Hyun Choi Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 94, 63-71 (2017-07-29) Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells.Xiao-Huang Xu et al.Scientific reports, 7(1), 10718-10718 (2017-09-08) Arachidonyl-2-Chloroethylamide Alleviates Cerebral Ischemia Injury Through Glycogen Synthase Kinase-3β-Mediated Mitochondrial Biogenesis and Functional Improvement.Fuhai Bai et al.Molecular neurobiology, 54(2), 1240-1253 (2016-01-29) Autophagic cell death of human hepatoma G2 cells mediated by procyanidins from Castanea mollissima Bl. Shell-induced reactive oxygen species generation.Yuqing Duan et al.Chemico-biological interactions, 224, 13-23 (2014-10-08) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells.Aleksey V Zholobenko et al.PloS one, 12(10), e0185691-e0185691 (2017-10-05) Triclocarban Disrupts the Epigenetic Status of Neuronal Cells and Induces AHR/CAR-Mediated Apoptosis.M Kajta et al.Molecular neurobiology, 56(5), 3113-3131 (2018-08-12) Anti-Tumor Effect of Pinus massoniana Bark Proanthocyanidins on Ovarian Cancer through Induction of Cell Apoptosis and Inhibition of Cell Migration.Jia Liu et al.PloS one, 10(11), e0142157-e0142157 (2015-11-06) A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer.Jing Dong et al.European journal of pharmacology, 828, 67-79 (2018-03-23) Curcumin reduces mitomycin C resistance in breast cancer stem cells by regulating Bcl-2 family-mediated apoptosis.Qian-Mei Zhou et al.Cancer cell international, 17, 84-84 (2017-09-30) Enhancing autophagy protects platelets in immune thrombocytopenia patients.Chun-Yan Wang et al.Annals of translational medicine, 7(7), 134-134 (2019-06-04) Hesperetin induces an apoptosis-triggered extrinsic pathway and a p53- independent pathway in human lung cancer H522 cells.Ramesh Elango et al.Journal of Asian natural products research, 20(6), 559-569 (2017-05-26) Knockdown of 15-kDa selenoprotein (Sep15) increases hLE cells' susceptibility to tunicamycin-induced apoptosis.Na Yin et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 20(8), 1307-1317 (2015-11-05) Effect of reduced glutathione supplementation on cryopreservation induced sperm cryoinjuries in Murrah bull semen.Chetna Gangwar et al.Animal reproduction science, 192, 171-178 (2018-03-22) Apoptosis of bone marrow mesenchymal stem cells caused by hypoxia/reoxygenation via multiple pathways.Tie-Long Chen et al.International journal of clinical and experimental medicine, 7(12), 4686-4697 (2015-02-11) Arecoline Increases Glycolysis and Modulates pH Regulator Expression in HA22T/VGH Hepatoma Cells, Leading to Increase of Intracellular CaHsiao-Ling Cheng et al.Journal of Cancer, 8(16), 3173-3182 (2017-11-22) Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways.X Meng et al.Free radical research, 48(7), 823-838 (2014-04-12) Optically-controlled bacterial metabolite for cancer therapy.Di-Wei Zheng et al.Nature communications, 9(1), 1680-1680 (2018-04-28) Luteolin induces myelodysplastic syndrome‑derived cell apoptosis via the p53‑dependent mitochondrial signaling pathway mediated by reactive oxygen species.Weimin Dong et al.International journal of molecular medicine, 42(2), 1106-1115 (2018-05-23) CRISPR/Cas9-Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors.Polina R Matre et al.Stem cells (Dayton, Ohio), 37(12), 1615-1628 (2019-10-02) Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes.Junfeng Zhou et al.Frontiers in pharmacology, 10, 497-497 (2019-05-30) IL-20 promotes hypoxia/reoxygenation-induced mitochondrial dysfunction and apoptosis in cardiomyocytes by upregulating oxidative stress by activating the PKC/NADPH oxidase pathway.Kun-Ling Tsai et al.Biochimica et biophysica acta. Molecular basis of disease, 1866(5), 165684-165684 (2020-01-19) Exposure to etoxazole induces mitochondria-mediated apoptosis in porcine trophectoderm and uterine luminal epithelial cells.Wonhyoung Park et al.Environmental pollution (Barking, Essex : 1987), 257, 113480-113480 (2019-11-21) Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.Pauline Rimmelé et al.EMBO reports, 16(9), 1164-1176 (2015-07-26) Neuroprotective effect of Annona muricata-derived polysaccharides in neuronal HT22 cell damage induced by hydrogen peroxide.Woo Sik Kim et al.Bioscience, biotechnology, and biochemistry, 84(5), 1001-1012 (2020-01-22) Photo-protective effect of americanin B against ultraviolet B-induced damage in cultured human keratinocytes.Jian Zheng et al.Environmental toxicology and pharmacology, 38(3), 891-900 (2014-12-03) DL0410 attenuates oxidative stress and neuroinflammation via BDNF/TrkB/ERK/CREB and Nrf2/HO-1 activation.Baoyue Zhang et al.International immunopharmacology, 86, 106729-106729 (2020-07-10) Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cellsYing Wang et al.Oncology letters, 13(6), 4762-4768 (2017-06-11) Proinflammatory Effect of Endothelial Microparticles Is Mitochondria Mediated and Modulated Through MAPKAPK2 (MAPK-Activated Protein Kinase 2) Leading to Attenuation of Cardiac Hypertrophy.Dipti Tripathi et al.Arteriosclerosis, thrombosis, and vascular biology, 39(6), 1100-1112 (2019-05-10) ULK1-regulated autophagy: A mechanism in cellular protection for ALDH2 against hyperglycemia.Min Liu et al.Toxicology letters, 283, 106-115 (2017-11-13) Coumestrol induces mitochondrial dysfunction by stimulating ROS production and calcium ion influx into mitochondria in human placental choriocarcinoma cells.Whasun Lim et al.Molecular human reproduction, 23(11), 786-802 (2017-10-19) 2,2'-Dipyridyl diselenide (Py2Se2) induces G1 arrest and apoptosis in human lung carcinoma (A549) cells through ROS scavenging and reductive stress.V V Gandhi et al.Metallomics : integrated biometal science, 12(8), 1253-1266 (2020-08-20) Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.Li Zhou et al.OncoTargets and therapy, 12, 1729-1739 (2019-03-19) Nicotine affects rat Leydig cell function in vivo and vitro via down-regulating some key steroidogenic enzyme expressions.Xiaoling Guo et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 110, 13-24 (2017-10-08) The age-related changes and differences in energy metabolism and glutamate-glutamine recycling in the d-gal-induced and naturally occurring senescent astrocytes in vitro.Pei Cao et al.Experimental gerontology, 118, 9-18 (2019-01-06) Truncated Bid Regulates Cisplatin Response via Activation of Mitochondrial Apoptosis Pathway in Ovarian Cancer.Yun Dai et al.Human gene therapy, 31(5-6), 325-338 (2020-02-07) Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.Jia Wang et al.Cells, 8(12) (2019-12-11) Fructose-coated Angstrom silver inhibits osteosarcoma growth and metastasis via promoting ROS-dependent apoptosis through the alteration of glucose metabolism by inhibiting PDK.Xiong-Ke Hu et al.Theranostics, 10(17), 7710-7729 (2020-07-21) Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12.Wei Sun et al.Acta pharmacologica Sinica, 38(6), 806-822 (2017-01-10) Amplification of CD20 Cross-Linking in Rituximab-Resistant B-Lymphoma Cells Enhances Apoptosis Induction by Drug-Free Macromolecular Therapeutics.Lian Li et al.ACS nano, 12(4), 3658-3670 (2018-03-30) Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.Iryna Bohovych et al.Scientific reports, 5, 13989-13989 (2015-09-15) Tilapia Skin Peptides Ameliorate Diabetic Nephropathy in STZ-Induced Diabetic Rats and HG-Induced GMCs by Improving Mitochondrial Dysfunction.Lin Jin et al.Marine drugs, 18(7) (2020-07-19) Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.Santanu Maji et al.Oncotarget, 6(18), 16623-16637 (2015-05-27) Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function.Man Liu et al.JCI insight, 4(1) (2019-01-11) Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.She-Hung Chan et al.International journal of molecular sciences, 21(7) (2020-04-08) Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53.Hyeon-Jun Shin et al.Scientific reports, 5, 15798-15798 (2015-11-03) Antitumor effect of a dual cancer-specific oncolytic adenovirus on prostate cancer PC-3 cells.Chuan-Xin Cui et al.Urologic oncology, 37(6), 352-352 (2019-01-23) Sodium hydrosulfide mitigates dexamethasone-induced osteoblast dysfunction by interfering with mitochondrial function.Jun Ma et al.Biotechnology and applied biochemistry, 66(4), 690-697 (2019-06-08) Evaluation of mitochondrial toxicity of cadmium in clam Ruditapes philippinarum using iTRAQ-based proteomics.Chenglong Ji et al.Environmental pollution (Barking, Essex : 1987), 251, 802-810 (2019-05-28) Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos.Ying-Jie Niu et al.Journal of pineal research, 68(2), e12627-e12627 (2019-11-28) Compound Fuling Granule Suppresses Ovarian Cancer Development and Progression by disrupting mitochondrial function, galactose and fatty acid metabolism.Shanming Ruan et al.Journal of Cancer, 9(18), 3382-3393 (2018-10-03) MiR-29 Targets PUMA to Suppress Oxygen and Glucose Deprivation/Reperfusion (OGD/R)-induced Cell Death in Hippocampal Neurons.Rong Wei et al.Current neurovascular research, 15(1), 47-54 (2018-04-07) Lycium barbarum polysaccharides protect human lens epithelial cells against oxidative stress-induced apoptosis and senescence.Bing Qi et al.PloS one, 9(10), e110275-e110275 (2014-10-22) Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics.Jarosław Walczak et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4388-4403 (2018-12-15) Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.Sailaja Ghanta et al.American journal of respiratory cell and molecular biology, 56(3), 300-309 (2016-09-17) Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation.Catarina Roma-Rodrigues et al.Bioorganic chemistry, 99, 103849-103849 (2020-04-24) DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2.Yuanyuan Kong et al.Cancer management and research, 11, 4797-4808 (2019-06-20) Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest.Jian Zhou et al.Respiratory research, 19(1), 96-96 (2018-05-23) Effects of novel brominated flame retardant TBPH and its metabolite TBMEHP on human vascular endothelial cells: Implication for human health risks.Ping Xiang et al.Environmental research, 156, 834-842 (2017-03-21) Salidroside protects PC-12 cells against amyloid β-induced apoptosis by activation of the ERK1/2 and AKT signaling pathways.Zheng-Luan Liao et al.International journal of molecular medicine, 43(4), 1769-1777 (2019-02-06) Effects of cashew gum and nanoparticles on cooled stallion semen.Kahynna Cavalcante Loureiro et al.Acta veterinaria Scandinavica, 62(1), 31-31 (2020-06-20) Therapeutic effects of matrine derivate MASM in mice with collagen-induced arthritis and on fibroblast-like synoviocytes.Yuming Zou et al.Scientific reports, 7(1), 2454-2454 (2017-05-28) Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway.Qiyan Cai et al.International journal of biological sciences, 12(12), 1415-1426 (2016-12-21) Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation.Dong Hun Lee et al.Redox biology, 32, 101496-101496 (2020-03-17) Aberrant Buildup of All-Trans-Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes to the Degeneration of the Retinal Pigment Epithelium.Junli Zhao et al.Investigative ophthalmology & visual science, 58(2), 1063-1075 (2017-02-14) Inhibitory effect of (-)-epigallocatechin-3-gallate and bleomycin on human pancreatic cancer MiaPaca-2 cell growth.Sabrina Bimonte et al.Infectious agents and cancer, 10, 22-22 (2015-08-01) Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis.Dongmei Han et al.Scientific reports, 8(1), 15137-15137 (2018-10-13) Drug-free macromolecular therapeutics induce apoptosis in cells isolated from patients with B cell malignancies with enhanced apoptosis induction by pretreatment with gemcitabine.Jiawei Wang et al.Nanomedicine : nanotechnology, biology, and medicine, 16, 217-225 (2019-01-15) Ewa Kochan et al.Molecules (Basel, Switzerland), 25(9) (2020-05-15)American ginseng, Panax quinquefolium (L.), is traditionally used in folk medicine. It exhibits a range of anti-inflammatory, hepatoprotective, anti-diabetic, anti-obesity, anti-hyperlipidemic and anti-carcinogenic effects. Its main components are ginsenosides, also known as panaxosides or triterpene saponins. In order to obtain... Mfn2 Affects Embryo Development via Mitochondrial Dysfunction and Apoptosis.Na Zhao et al.PloS one, 10(5), e0125680-e0125680 (2015-05-16) Codelivery of sorafenib and curcumin by directed self-assembled nanoparticles enhances therapeutic effect on hepatocellular carcinoma.Haiqiang Cao et al.Molecular pharmaceutics, 12(3), 922-931 (2015-01-27) Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.Xu Li et al.Cancer letters, 357(1), 219-230 (2014-12-03) Limonin ameliorates acetaminophen-induced hepatotoxicity by activating Nrf2 antioxidative pathway and inhibiting NF-κB inflammatory response via upregulating Sirt1.Runyu Yang et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 69, 153211-153211 (2020-04-08) Arabinogalactan derived from Lycium barbarum fruit inhibits cancer cell growth via cell cycle arrest and apoptosis.Guiping Gong et al.International journal of biological macromolecules, 149, 639-650 (2020-01-29) Effect of Cryopreservation on Casa Characteristics, Mitochondrial Transmembrane Potential, Plasma and Acrosome Integrities, Morphology and in vivo Fertility of Buffalo Bull Spermatozoa.H Ahmed et al.Cryo letters, 40(3), 173-180 (2019-05-17) Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke.Yang Jiao et al.Molecular biology reports, 47(4), 2417-2425 (2020-02-29) NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter.Dong-Eun Lee et al.Cell death & disease, 11(1), 38-38 (2020-01-22) Individual and seasonal variations in the quality of fractionated boar ejaculates.L Zasiadczyk et al.Theriogenology, 83(8), 1287-1303 (2015-03-01) Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis.Huan Qin et al.Frontiers in pharmacology, 11, 156-156 (2020-03-18) Facilitation of brain mitochondrial activity by 5-aminolevulinic acid in a mouse model of Alzheimer's disease.Chiori Omori et al.Nutritional neuroscience, 20(9), 538-546 (2016-06-23) Inhibitory Effect of Damulin B from Gynostemma pentaphyllum on Human Lung Cancer Cells.Shao-Fang Xing et al.Planta medica, 85(5), 394-405 (2018-12-19) TRAIL attenuates sulforaphane-mediated Nrf2 and sustains ROS generation, leading to apoptosis of TRAIL-resistant human bladder cancer cells.Cheng-Yun Jin et al.Toxicology and applied pharmacology, 352, 132-141 (2018-05-25) Cinnamaldehyde, a Promising Natural Preservative Against Aspergillus flavus.Su Qu et al.Frontiers in microbiology, 10, 2895-2895 (2020-01-11) Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy.Stefano De De Cillà et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(5), 1725-1738 (2017-07-26) Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway.Wan-Rong Huang et al.Molecules (Basel, Switzerland), 19(6), 7785-7797 (2014-06-26) Neuroprotective Effect of ent-Kaur-15-en-17-al-18-oic Acid on Amyloid Beta Peptide-Induced Oxidative Apoptosis in Alzheimer's Disease.Caiyun Zhang et al.Molecules (Basel, Switzerland), 25(1) (2020-01-08) Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells.Nini Cao et al.Frontiers in pharmacology, 11, 1094-1094 (2020-08-15) Parkin Modulates ERRα/eNOS Signaling Pathway in Endothelial Cells.Weiwei Xia et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(5), 2022-2034 (2018-09-24) Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations.Mariia Lunova et al.Cellular and molecular life sciences : CMLS, 77(14), 2815-2838 (2019-10-05) Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer.David R Wallace et al.International journal of molecular medicine, 44(1), 145-156 (2019-05-23) Zeylenone inhibits proliferation and promotes apoptosis in ovarian carcinoma cells via Janus kinase 2 / signal transducers and activators of transcription 3 pathways.Xiaoli Xu et al.The journal of obstetrics and gynaecology research, 44(8), 1451-1457 (2018-07-06) Responses of solid tumor cells in DMEM to reactive oxygen species generated by non-thermal plasma and chemically induced ROS systems.Neha Kaushik et al.Scientific reports, 5, 8587-8587 (2015-02-27) Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway.Kyoung Ah Kang et al.In vitro cellular & developmental biology. Animal, 51(3), 300-309 (2014-11-09) Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models.Yan Liu et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 21(23), 5338-5348 (2015-07-15) Neuroprotective effects of Dendropanax morbifera leaves on glutamate-induced oxidative cell death in HT22 mouse hippocampal neuronal cells.Hye-Jin Park et al.Journal of ethnopharmacology, 251, 112518-112518 (2019-12-31) Effect of SOX2 Repression on Corneal Endothelial Cells.Jin Sun Hwang et al.International journal of molecular sciences, 21(12) (2020-06-25) Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways.Mengyao Zhao et al.Carbohydrate polymers, 224, 115171-115171 (2019-09-02) Trametenolic acid B protects against cerebral ischemia and reperfusion injury through modulation of microRNA-10a and PI3K/Akt/mTOR signaling pathways.Junzhi Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 112, 108692-108692 (2019-02-25) 18α-Glycyrrhetinic acid (GA) ameliorates fructose-induced nephropathy in mice by suppressing oxidative stress, dyslipidemia and inflammation.Xiaoli Cheng et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 109702-109702 (2020-02-29) Mechanistic Study of Bakuchiol-Induced Anti-breast Cancer Stem Cell andLi Li et al.Frontiers in pharmacology, 8, 746-746 (2017-11-03) Induced pluripotent stem cell-derived conditional medium promotes Leydig cell anti-apoptosis and proliferation via autophagy and Wnt/β-catenin pathway.Xiaoling Guo et al.Journal of cellular and molecular medicine, 22(7), 3614-3626 (2018-04-19) Luteolin induces cell cycle arrest and apoptosis through extrinsic and intrinsic signaling pathways in MCF-7 breast cancer cells.Su-Ho Park et al.Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 33(3), 219-231 (2014-10-02) Actinidia chinensis planch polysaccharide protects against hypoxia‑induced apoptosis of cardiomyocytes in vitro.Qiang Wang et al.Molecular medicine reports, 18(1), 193-201 (2018-05-12) Human sperm motility is downregulated by the AMPK activator A769662.V Calle-Guisado et al.Andrology, 5(6), 1131-1140 (2017-10-06) Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury.Sun Woo Lim et al.Aging, 11(15), 5548-5569 (2019-08-11) Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis.Feifei Kong et al.Cell death & disease, 8(10), e3121-e3121 (2017-10-13) Aldehyde Dehydrogenase-2 Attenuates Myocardial Remodeling and Contractile Dysfunction Induced by a High-Fat Diet.Chuanbao Li et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(5), 1843-1853 (2018-08-10) Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization.Xiucui Ma et al.Journal of the American Heart Association, 8(4), e010866-e010866 (2019-02-19) Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl) imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity.Qi-Pin Qin et al.European journal of medicinal chemistry, 89, 77-87 (2014-12-03) SNAP reverses temozolomide resistance in human glioblastoma multiforme cells through down-regulation of MGMT.Chia-Kuang Tsai et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 14171-14184 (2019-11-15) Effects of organophosphorus flame retardant TDCPP on normal human corneal epithelial cells: Implications for human health.Ping Xiang et al.Environmental pollution (Barking, Essex : 1987), 230, 22-30 (2017-06-24) Age-related changes in the mitochondria of human mural granulosa cells.Yifan Liu et al.Human reproduction (Oxford, England), 32(12), 2465-2473 (2017-10-19) Melatonin Attenuates Cardiac Reperfusion Stress by Improving OPA1-Related Mitochondrial Fusion in a Yap-Hippo Pathway-Dependent Manner.Shuxian Ma et al.Journal of cardiovascular pharmacology, 73(1), 27-39 (2018-11-13) Tailored Reconstituted Lipoprotein for Site-Specific and Mitochondria-Targeted Cyclosporine A Delivery to Treat Traumatic Brain Injury.Lepei Chen et al.ACS nano, 14(6), 6636-6648 (2020-05-29) LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells.Y Guler et al.Bratislavske lekarske listy, 1(5), 334-338 (2020-05-02) Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway.Wuyang He et al.Skeletal muscle, 10(1), 25-25 (2020-09-17) Design, Synthesis, and Anticancer Evaluation of Novel Indole Derivatives of Ursolic Acid as Potential Topoisomerase II Inhibitors.A-Liang Li et al.International journal of molecular sciences, 21(8) (2020-04-25) Quercetin, a Lead Compound against Type 2 Diabetes Ameliorates Glucose Uptake via AMPK Pathway in Skeletal Muscle Cell Line.R Dhanya et al.Frontiers in pharmacology, 8, 336-336 (2017-06-24) Ginseng-Sanqi-Chuanxiong (GSC) Extracts Ameliorate Diabetes-Induced Endothelial Cell Senescence through Regulating Mitophagy via the AMPK Pathway.Xue Wang et al.Oxidative medicine and cellular longevity, 2020, 7151946-7151946 (2020-09-24) Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells.Mohana Krishna Gopisetty et al.Journal of nanobiotechnology, 17(1), 9-9 (2019-01-24) Phospho-valproic acid (MDC-1112) suppresses glioblastoma growth in preclinical models through the inhibition of STAT3 phosphorylation.Dingyuan Luo et al.Carcinogenesis, 40(12), 1480-1491 (2019-04-18) Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma.Zhu-Ling Guo et al.Journal of hematology & oncology, 8, 99-99 (2015-08-20) Liraglutide protects renal mesangial cells against hyperglycemia‑mediated mitochondrial apoptosis by activating the ERK‑Yap signaling pathway and upregulating Sirt3 expression.Jian Li et al.Molecular medicine reports, 19(4), 2849-2860 (2019-03-01) Lipid storage droplet protein 5 reduces sodium palmitate‑induced lipotoxicity in human normal liver cells by regulating lipid metabolism‑related factors.Xueqiang Ma et al.Molecular medicine reports, 20(2), 879-886 (2019-06-08) TOM40 Inhibits Ovarian Cancer Cell Growth by Modulating Mitochondrial Function Including Intracellular ATP and ROS Levels.Wookyeom Yang et al.Cancers, 12(5) (2020-05-28) Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction.Siyu Li et al.Food & function, 11(4), 3361-3370 (2020-04-02) Lunasin attenuates oxidant-induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE-/- mice by up-regulating heme oxygenase-1 via PI3K/Akt/Nrf2/ARE pathway.Lili Gu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(4), 4836-4850 (2019-01-03) Sp-CBL inhibits white spot syndrome virus replication by enhancing apoptosis in mud crab (Scylla paramamosain).Tongtong Kong et al.Developmental and comparative immunology, 105, 103580-103580 (2020-01-07) Hydrogen sulfide attenuates lung ischemia-reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats.Tao Jiang et al.Surgery, 165(5), 1014-1026 (2019-03-03) Knockdown of lncRNA HCP5 protects against cerebral ischemia/reperfusion injury by regulating miR-652-3p.J D Gao et al.Journal of biological regulators and homeostatic agents, 34(3), 893-900 (2020-07-14) Two-way immune effects of deoxynivalenol in weaned piglets and porcine alveolar macrophages: Due mainly to its exposure dosage.Dandan Liu et al.Chemosphere, 249, 126464-126464 (2020-04-02) Individual and combined effects of Aflatoxin BHongyuan Zhou et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 103, 18-27 (2017-02-23) Maduramicin induces apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.Xiuge Gao et al.Toxicology in vitro : an international journal published in association with BIBRA, 50, 190-200 (2018-03-28) NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.Smriti Shukla et al.Pesticide biochemistry and physiology, 123, 74-86 (2015-08-13) Intricatinol synergistically enhances the anticancerous activity of cisplatin in human A549 cells via p38 MAPK/p53 signalling.Vipendra Kumar Singh et al.Apoptosis : an international journal on programmed cell death, 22(10), 1273-1286 (2017-08-02) Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.Wenjie Guo et al.Nature communications, 8(1), 2168-2168 (2017-12-20) Maresin conjugates in tissue regeneration 1 prevents lipopolysaccharide-induced cardiac dysfunction through improvement of mitochondrial biogenesis and function.Yi Yang et al.Biochemical pharmacology, 177, 114005-114005 (2020-05-04) Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo.Hui-Hui Zhang et al.Molecular carcinogenesis, 57(1), 44-56 (2017-08-24) Screening Mold Colonies by Using Two Toxicity Assays Revealed Indoor Strains of Aspergillus calidoustus Producing Ophiobolins G and K.Marja Johanna Salo et al.Toxins, 11(12) (2019-11-27) Effect of cigarette smoke on DNA damage, oxidative stress, and morphological alterations in mouse testis and spermatozoa.Sebastiano La Maestra et al.International journal of hygiene and environmental health, 218(1), 117-122 (2014-09-28) Hexavalent chromium induced oxidative stress and apoptosis in Pycnoporus sanguineus.Mi Feng et al.Environmental pollution (Barking, Essex : 1987), 228, 128-139 (2017-05-22) Targeting mitochondrial respiration selectively sensitizes pediatric acute lymphoblastic leukemia cell lines and patient samples to standard chemotherapy.Xuedong Fu et al.American journal of cancer research, 7(12), 2395-2405 (2018-01-10) The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition.Matthijs J van Haren et al.The international journal of biochemistry & cell biology, 98, 127-136 (2018-03-20) Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells.Qiong Shi et al.Toxicology letters, 306, 25-34 (2019-02-12) Walnut ( Juglans regia) Peptides Reverse Sleep Deprivation-Induced Memory Impairment in Rat via Alleviating Oxidative Stress.Shuguang Wang et al.Journal of agricultural and food chemistry, 66(40), 10617-10627 (2018-09-19) Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kγ/Akt inhibition.Yan Shen et al.British journal of pharmacology, 175(10), 1621-1636 (2018-02-20) Anti-proliferation of triple-negative breast cancer cells with physagulide P: ROS/JNK signaling pathway induces apoptosis and autophagic cell death.Pei Yu et al.Oncotarget, 8(38), 64032-64049 (2017-10-04) Poly (ADP-ribose) polymerase-1: an emerging target in right ventricle dysfunction associated with pulmonary hypertension.Gurpreet Kaur et al.Pulmonary pharmacology & therapeutics, 30, 66-79 (2014-12-08) Glucose fluctuation increased hepatocyte apoptosis under lipotoxicity and the involvement of mitochondrial permeability transition opening.Xueyao Yin et al.Journal of molecular endocrinology, 55(3), 169-181 (2015-10-16) Inhibition of Phosphoglycerate Mutase 5 Reduces Necroptosis in Rat Hearts Following Ischemia/Reperfusion Through Suppression of Dynamin-Related Protein 1.Lang She et al.Cardiovascular drugs and therapy, 33(1), 13-23 (2019-01-15) Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response.Xiaochen Qiu et al.International immunopharmacology, 84, 106517-106517 (2020-05-04) Low‑dose radiation‑induced apoptosis in human leukemia K562 cells through mitochondrial pathways.Yong Xin et al.Molecular medicine reports, 10(3), 1569-1575 (2014-07-26) Effect of sulphoraphane on newborn mouse cardiomyocytes undergoing ischaemia/reperfusion injury.Na Peng et al.Pharmaceutical biology, 57(1), 753-759 (2019-11-07) Polyphenol Stilbenes from Fenugreek (Trigonella foenum-graecum L.) Seeds Improve Insulin Sensitivity and Mitochondrial Function in 3T3-L1 Adipocytes.Gang Li et al.Oxidative medicine and cellular longevity, 2018, 7634362-7634362 (2018-07-04) Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco(endo)plasmic reticulum-mitochondria coupling in hyperglycemic cardiomyocytes.Erkan Tuncay et al.Mitochondrion, 44, 41-52 (2018-01-09) A Low Dose of Nanoparticulate Silver Induces Mitochondrial Dysfunction and Autophagy in Adult Rat Brain.Joanna Skalska et al.Neurotoxicity research, 38(3), 650-664 (2020-06-27) Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease.Lei Zhang et al.Biomaterials, 197, 393-404 (2019-02-01) Differences in toxicity, mitochondrial function and miRNome in human cells exposed in vitro to Cd as CdS quantum dots or ionic Cd.Laura Paesano et al.Journal of hazardous materials, 393, 122430-122430 (2020-03-11) A reactive oxygen species activation mechanism contributes to Sophoridine-induced apoptosis in rat liver BRL-3A cells.Mingning Qiu et al.Journal of ethnopharmacology, 213, 376-383 (2017-11-06) UCP2 regulates cholangiocarcinoma cell plasticity via mitochondria-to-AMPK signals.Jianhua Yu et al.Biochemical pharmacology, 166, 174-184 (2019-05-16) PGC1α promotes cisplatin resistance in human ovarian carcinoma cells through upregulation of mitochondrial biogenesis.Luyan Shen et al.International journal of oncology, 53(1), 404-416 (2018-05-12) Apoptotic effects of norfloxacin on corneal endothelial cells.Ting-Jun Fan et al.Naunyn-Schmiedeberg's archives of pharmacology, 393(1), 77-88 (2019-08-20) Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis.Andrea Masotti et al.Aging, 6(12), 1094-1108 (2015-01-09) Neuroprotective Effects of Acetylcholinesterase Inhibitory Peptides from Anchovy (Coilia mystus) against Glutamate-Induced Toxicity in PC12 Cells.Tiantian Zhao et al.Journal of agricultural and food chemistry, 65(51), 11192-11201 (2017-12-01) Pentacyclic triterpenoid-rich fraction of the Hardy kiwi (Actinidia arguta) improves brain dysfunction in high fat diet-induced obese mice.Jeong Su Ha et al.Scientific reports, 10(1), 5788-5788 (2020-04-03) Repeated administrations of Mn3O4 nanoparticles cause testis damage and fertility decrease through PPAR-signaling pathway.Xiao Zhang et al.Nanotoxicology, 14(3), 326-340 (2020-01-08) Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-FePoorani Krishnan et al.Scientific reports, 7(1), 10962-10962 (2017-09-10) BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1α pathway in spermatogenic cells both in vitro and in vivo.Wang Yang et al.Toxicology and applied pharmacology, 376, 17-37 (2019-05-16) pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities.Jinming Zhang et al.Acta biomaterialia, 58, 349-364 (2017-04-30) Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells.Ding-Ping Bai et al.International journal of nanomedicine, 12, 6521-6535 (2017-09-19) Polyphenol epigallocatechin-3-gallate inhibits hypoxia/reoxygenation-induced H9C2 cell apoptosis.Wenlong Wang et al.Minerva medica, 109(2), 95-102 (2017-11-09) Mitochondrial activity and cytoskeleton organization in three pronuclei oocytes after intracytoplasmic sperm injection.Tuğba Kotil et al.Zygote (Cambridge, England), 26(4), 319-325 (2018-10-04) A Cronobacter turicensis O1 antigen-specific monoclonal antibody inhibits bacterial motility and entry into epithelial cells.Kristina Schauer et al.Infection and immunity, 83(3), 876-887 (2014-12-24) Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing.Madhuri Basak et al.Antioxidants & redox signaling, 32(11), 766-784 (2019-12-14) Phenotypic Variation in Mitochondria-Related Performance Traits Across New Zealand Snail Populations.Emma S Greimann et al.Integrative and comparative biology, 60(2), 275-287 (2020-06-27) Antioxidant and Anti-Apoptotic Activity of Octadecaneuropeptide Against 6-OHDA Toxicity in Cultured Rat Astrocytes.Hadhemi Kaddour et al.Journal of molecular neuroscience : MN, 69(1), 1-16 (2018-10-22) Mn-TAT PTD-Ngb attenuates oxidative injury by an enhanced ROS scavenging ability and the regulation of redox signaling pathway.Cui Zhang et al.Scientific reports, 9(1), 20103-20103 (2019-12-29) miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.Jie-Jie Zhang et al.Mechanisms of ageing and development, 164, 8-19 (2017-03-30) Dynamin-related protein 1 is involved in micheliolide-induced breast cancer cell death.Yongsheng Jia et al.OncoTargets and therapy, 8, 3371-3381 (2015-12-02) Functional nanosome for enhanced mitochondria-targeted gene delivery and expression.Yoonhee Bae et al.Mitochondrion, 37, 27-40 (2017-07-04) GPR39 protects against corticosterone-induced neuronal injury in hippocampal cells through the CREB-BDNF signaling pathway.Fengfeng Mo et al.Journal of affective disorders, 272, 474-484 (2020-06-20) Beryllium inhibits apoptosis via mitochondria in beryllium-induced lung disease in the rat.Zhihong Liu et al.Experimental lung research, 45(3-4), 92-100 (2019-06-04) Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism.Siyu Wu et al.Experimental neurology, 309, 67-78 (2018-08-05) Analysis of proliferation and apoptotic induction by 20 steroid glycosides in 143B osteosarcoma cells in vitro.C I Delebinski et al.Cell proliferation, 48(5), 600-610 (2015-08-25) Antioxidant and Neuroprotective Potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson's Disease Model.Joana Silva et al.Marine drugs, 17(2) (2019-02-06) Asiatic acid protects differentiated PC12 cells from Aβ25-35-induced apoptosis and tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β signaling.Wenjing Cheng et al.Life sciences, 208, 96-101 (2018-07-19) K6PC-5 Activates SphK1-Nrf2 Signaling to Protect Neuronal Cells from Oxygen Glucose Deprivation/Re-Oxygenation.Hua Liu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 51(4), 1908-1920 (2018-12-07) Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.Xinwen Liao et al.Journal of Cancer, 10(16), 3678-3690 (2019-07-25) Cinobufagin Induces Apoptosis in Osteosarcoma Cells Via the Mitochondria-Mediated Apoptotic Pathway.Guo Dai et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 46(3), 1134-1147 (2018-04-19) Ninjurin-1 upregulated by TNFα receptor 1 stimulates monocyte adhesion to human TNFα-activated endothelial cells; benefic effects of amlodipine.Laura Toma et al.Life sciences, 249, 117518-117518 (2020-03-10) Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway.Yan Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 105, 1172-1182 (2018-07-20) Tafazzin-dependent cardiolipin composition in C6 glioma cells correlates with changes in mitochondrial and cellular functions, and cellular proliferation.Sarah Gürtler et al.Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(4), 452-465 (2019-01-15) Biological evaluation of octahydropyrazin[2,1-a:5,4-a']diisoquinoline derivatives as potent anticancer agents.Agnieszka Gornowicz et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39(6), 1010428317701641-1010428317701641 (2017-06-18) Metformin partially reverses the carboplatin-resistance in NSCLC by inhibiting glucose metabolism.Yong Liu et al.Oncotarget, 8(43), 75206-75216 (2017-11-02) Metformin upregulates mitophagy in patients with T2DM: A randomized placebo-controlled study.Shipra Bhansali et al.Journal of cellular and molecular medicine, 24(5), 2832-2846 (2020-01-25) Effect of mitochondrial apoptotic activation through the mitochondrial membrane permeability transition pore on yak meat tenderness during postmortem aging.Lin-Lin Wang et al.Food chemistry, 234, 323-331 (2017-05-30) Renalase Attenuates Mouse Fatty Liver Ischemia/Reperfusion Injury through Mitigating Oxidative Stress and Mitochondrial Damage via Activating SIRT1.Tao Zhang et al.Oxidative medicine and cellular longevity, 2019, 7534285-7534285 (2020-01-18) Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H2O2-induced apoptosis by regulating ROS-ASK1-JNK/p38 MAPK signaling.Li-Min Zhang et al.BMC complementary medicine and therapies, 20(1), 54-54 (2020-02-16) Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels.Daniel León-Aparicio et al.International journal of molecular sciences, 20(20) (2019-10-12) Resveratrol preserves mitochondrial function, stimulates mitochondrial biogenesis, and attenuates oxidative stress in regulatory T cells of mice fed a high-fat diet.Bin Wang et al.Journal of food science, 79(9), H1823-H1831 (2014-08-27) MicroRNA-141 protects PC12 cells against hypoxia/reoxygenation-induced injury via regulating Keap1-Nrf2 signaling pathway.Bin Zhou et al.Journal of bioenergetics and biomembranes, 51(4), 291-300 (2019-07-06) Analysis of apoptosis induced by perfluorooctane sulfonates (PFOS) in mouse Leydig cells in vitro.De-Yong Zhang et al.Toxicology mechanisms and methods, 25(1), 21-25 (2014-09-30) Neuroprotective action of tea polyphenols on oxidative stress-induced apoptosis through the activation of the TrkB/CREB/BDNF pathway and Keap1/Nrf2 signaling pathway in SH-SY5Y cells and mice brain.Guoyuan Qi et al.Food & function, 8(12), 4421-4432 (2017-11-02) AMPK activation by Tanshinone IIA protects neuronal cells from oxygen-glucose deprivation.Yingfeng Weng et al.Oncotarget, 9(4), 4511-4521 (2018-02-13) Thyroid hormone protects cardiomyocytes from H2O2-induced oxidative stress via the PI3K-AKT signaling pathway.Bin Zeng et al.Experimental cell research, 380(2), 205-215 (2019-05-07) Mitochondrial translocation of estrogen receptor β affords resistance to oxidative insult-induced apoptosis and contributes to the pathogenesis of endometriosis.Tien-Ling Liao et al.Free radical biology & medicine, 134, 359-373 (2019-01-27) Flupirtine derivatives as potential treatment for the neuronal ceroid lipofuscinoses.Joelle Makoukji et al.Annals of clinical and translational neurology, 5(9), 1089-1103 (2018-09-27) Structure-function relationships of HDL in diabetes and coronary heart disease.Mathias Cardner et al.JCI insight, 5(1) (2019-12-13) Mitochondrial OXPHOS is involved in the protective effects of L-arginine against heat-induced low sperm motility of boar.Yansen Li et al.Journal of thermal biology, 84, 236-244 (2019-08-31) LASS2 inhibits proliferation and induces apoptosis in HepG2 cells by affecting mitochondrial dynamics, the cell cycle and the nuclear factor‑κB pathways.Yan Yang et al.Oncology reports, 41(5), 3005-3014 (2019-03-22) TIPE attenuates the apoptotic effect of radiation and cisplatin and promotes tumor growth via JNK and p38 activation in Raw264.7 and EL4 cells.Yao Liu et al.Oncology reports, 39(6), 2688-2694 (2018-04-06) Smart Biomimetic Nanocomposites Mediate Mitochondrial Outcome through Aerobic Glycolysis Reprogramming: A Promising Treatment for Lymphoma.Qiangqiang Zhao et al.ACS applied materials & interfaces, 12(20), 22687-22701 (2020-04-25) Peroxiredoxin II Maintains the Mitochondrial Membrane Potential against Alcohol-Induced Apoptosis in HT22 Cells.Mei-Hua Jin et al.Antioxidants (Basel, Switzerland), 9(1) (2019-12-22) LPS challenge increased intestinal permeability, disrupted mitochondrial function and triggered mitophagy of piglets.Shuting Cao et al.Innate immunity, 24(4), 221-230 (2018-04-13) Preparation of intact mitochondria using free-flow isoelectric focusing with post-pH gradient sample injection for morphological, functional and proteomics studies.Yu-Chen He et al.Analytica chimica acta, 982, 200-208 (2017-07-25) PI3K and Bcl-2 inhibition primes glioblastoma cells to apoptosis through downregulation of Mcl-1 and Phospho-BAD.Fresia Pareja et al.Molecular cancer research : MCR, 12(7), 987-1001 (2014-04-24) Mitochondria changes and metabolome differences of bovine longissimus lumborum and psoas major during 24 h postmortem.Qianqian Yu et al.Meat science, 166, 108112-108112 (2020-04-18) Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.Jie Wang et al.OncoTargets and therapy, 11, 7031-7040 (2018-11-10) Sperm viability, reactive oxygen species, and DNA fragmentation index combined can discriminate between above- and below-average fertility bulls.A Kumaresan et al.Journal of dairy science, 100(7), 5824-5836 (2017-05-10) Resveratrol ameliorates disorders of mitochondrial biogenesis and mitophagy in rats continuously exposed to benzo(a)pyrene from embryonic development through adolescence.Kai-Ge Chen et al.Toxicology, 442, 152532-152532 (2020-07-04) Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity.Yubin Li et al.Nanotoxicology, 9(3), 344-355 (2014-07-02) Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing.Natascha Sommer et al.Science advances, 6(16), eaba0694-eaba0694 (2020-05-20) DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage.Xiao Xiao et al.Nature communications, 9(1), 4342-4342 (2018-10-20) Synergistic antitumor effect of polysaccharide from Lachnum sp. in combination with cyclophosphamide in hepatocellular carcinoma.Shuai Zong et al.Carbohydrate polymers, 196, 33-46 (2018-06-13) Growth-inhibitory and chemosensitizing effects of microRNA-31 in human glioblastoma multiforme cells.Rong-Jing Zhou et al.International journal of molecular medicine, 36(4), 1159-1164 (2015-08-28) HIV gp120 in the Lungs of Antiretroviral Therapy-treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci.Paul J Collini et al.American journal of respiratory and critical care medicine, 197(12), 1604-1615 (2018-01-25) Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.Yong-Fang Yao et al.Biochemical pharmacology, 137, 10-28 (2017-05-01) Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses.Zhaohui Jiang et al.Scientific reports, 10(1), 6427-6427 (2020-04-15) Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.Hong Ming Huang et al.G3 (Bethesda, Md.), 7(9), 3133-3144 (2017-07-29) Roles of eIF3m in the tumorigenesis of triple negative breast cancer.Wei Han et al.Cancer cell international, 20, 141-141 (2020-05-06) Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles.Pengcheng Yu et al.Acta biomaterialia, 14, 115-124 (2014-12-17) Indoxyl sulfate induces intestinal barrier injury through IRF1-DRP1 axis-mediated mitophagy impairment.Yinghui Huang et al.Theranostics, 10(16), 7384-7400 (2020-07-10) Novel α-Lipoic Acid/3-n-Butylphthalide Conjugate Enhances Protective Effects against Oxidative Stress and 6-OHDA Induced Neuronal Damage.Kwanchanok Uppakara et al.ACS chemical neuroscience, 11(11), 1634-1642 (2020-05-07) Irbesartan attenuates advanced glycation end products-mediated damage in diabetes-associated osteoporosis through the AGEs/RAGE pathway.Yan-Zhen Cheng et al.Life sciences, 205, 184-192 (2018-04-28) The natural sweetener metabolite steviol inhibits the proliferation of human osteosarcoma U2OS cell line.Jun-Ming Chen et al.Oncology letters, 15(4), 5250-5256 (2018-03-20) Antibiotic tigecycline enhances cisplatin activity against human hepatocellular carcinoma through inducing mitochondrial dysfunction and oxidative damage.Jun Tan et al.Biochemical and biophysical research communications, 483(1), 17-23 (2017-01-11) Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer.Liping Shan et al.Aging, 11(18), 7780-7795 (2019-09-24) Taraxerol Induces Cell Apoptosis through A Mitochondria-Mediated Pathway in HeLa Cells.Xiangyang Yaoi et al.Cell journal, 19(3), 512-519 (2017-08-25) Bis(ethylmaltolato)oxidovanadium (IV) mitigates neuronal apoptosis resulted from amyloid-beta induced endoplasmic reticulum stress through activating peroxisome proliferator-activated receptor γ.Zhijun He et al.Journal of inorganic biochemistry, 208, 111073-111073 (2020-05-30) Green Tea Seed Oil Suppressed Aβ1⁻42-Induced Behavioral and Cognitive Deficit via the Aβ-Related Akt Pathway.Jong Min Kim et al.International journal of molecular sciences, 20(8) (2019-04-18) Molecular insights for the biological interactions between polyethylene glycol and cells.Li Xu et al.Biomaterials, 147, 1-13 (2017-09-20) Total triterpenoids from the fruits of Chaenomeles speciosa exerted gastroprotective activities on indomethacin-induced gastric damage via modulating microRNA-423-5p-mediated TFF/NAG-1 and apoptotic pathways.Haibo He et al.Food & function, 11(1), 662-679 (2020-01-03) Fumonisin B1-induced oxidative stress triggers Nrf2-mediated antioxidant response in human hepatocellular carcinoma (HepG2) cells.Thilona Arumugam et al.Mycotoxin research, 35(1), 99-109 (2018-11-10) Synoviocyte apoptosis may differentiate responder and non-responder patients to methotrexate treatment in rheumatoid arthritis.Sang Yeob Lee et al.Archives of pharmacal research, 37(10), 1286-1294 (2014-07-06) The soluble VEGF receptor sFlt-1 contributes to endothelial dysfunction in IgA nephropathy.Yaling Zhai et al.PloS one, 15(8), e0234492-e0234492 (2020-08-14) N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α alleviates phenylephrine‑induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes.Zuheng Liu et al.Molecular medicine reports, 18(2), 2142-2152 (2018-06-15) Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction.Naoki Fujitani et al.Scientific reports, 9(1), 14764-14764 (2019-10-16) In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells.Noraini Nordin et al.Scientific reports, 9(1), 1614-1614 (2019-02-09) S-Allyl Cysteine Alleviates Hydrogen Peroxide Induced Oxidative Injury and Apoptosis through Upregulation of Akt/Nrf-2/HO-1 Signaling Pathway in HepG2 Cells.Chitra Basu et al.BioMed research international, 2018, 3169431-3169431 (2018-12-06) Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway.Ruiying Tong et al.Oxidative medicine and cellular longevity, 2020, 2543504-2543504 (2020-07-04) Triterpenoids fromJuan Cen et al.Oncotarget, 8(41), 69465-69476 (2017-10-21) Prediction of the mechanisms of Xiaoai Jiedu Recipe in the treatment of breast cancer: A comprehensive approach study with experimental validation.Yuyun Li et al.Journal of ethnopharmacology, 252, 112603-112603 (2020-01-26) Interleukin-35 inhibits human umbilical vein endothelial cell injury induced by sera from pre-eclampsia patients by up-regulating S100A8 protein expression.Ming Li et al.Hypertension in pregnancy, 39(2), 126-138 (2020-03-24) Mitochondrial dysfunction in dopaminergic neurons differentiated from exfoliated deciduous tooth-derived pulp stem cells of a child with Rett syndrome.Saki Hirofuji et al.Biochemical and biophysical research communications, 498(4), 898-904 (2018-03-15) Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate diquat-induced intestinal barrier dysfunction in C57BL/6 mice through their antioxidant activity.Lei Qiao et al.Food & function, 11(4), 3020-3031 (2020-04-04) Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy.Kaiyuan Ni et al.Nature communications, 9(1), 4321-4321 (2018-10-20) Zinc phthalocyanine encapsulated in polymer micelles as a potent photosensitizer for the photodynamic therapy of osteosarcoma.Wei Yu et al.Nanomedicine : nanotechnology, biology, and medicine, 14(4), 1099-1110 (2018-02-21) Loss of fructose-1,6-bisphosphatase induces glycolysis and promotes apoptosis resistance of cancer stem-like cells: an important role in hexavalent chromium-induced carcinogenesis.Jin Dai et al.Toxicology and applied pharmacology, 331, 164-173 (2017-06-19) Autophagy inhibition enhances radiosensitivity of Eca‑109 cells via the mitochondrial apoptosis pathway.Hua Tao et al.International journal of oncology, 52(6), 1853-1862 (2018-04-06) Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells.Y Xue et al.Human & experimental toxicology, 37(12), 1293-1309 (2018-04-17) Inhibiting the mobilization of Ly6C(high) monocytes after acute myocardial infarction enhances the efficiency of mesenchymal stromal cell transplantation and curbs myocardial remodeling.Wenbin Lu et al.American journal of translational research, 7(3), 587-597 (2015-06-06) ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma through Mitochondrial Dysfunction and p70S6K Signaling Pathway.Shih-Wei Wang L et al.International journal of molecular sciences, 21(5) (2020-03-01) 3-Bromopyruvate enhances TRAIL-induced apoptosis in human nasopharyngeal carcinoma cells through CHOP-dependent upregulation of TRAIL-R2.Zhou Can et al.Anti-cancer drugs, 28(7), 739-749 (2017-05-05) Pyrroloquinoline quinone protects nucleus pulposus cells from hydrogen peroxide-induced apoptosis by inhibiting the mitochondria-mediated pathway.Lianjun Yang et al.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 24(8), 1702-1710 (2014-10-29) CaSR activates PKCδ to induce cardiomyocyte apoptosis via ER stress‑associated apoptotic pathways during ischemia/reperfusion.Chong Liu et al.International journal of molecular medicine, 44(3), 1117-1126 (2019-07-02) Mitophagy is increased during erythroid differentiation in β-thalassemia.Limei Wu et al.International journal of hematology, 105(2), 162-173 (2016-11-01) Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria-dependent pathway.Yuwan Zhao et al.Oncology letters, 17(5), 4277-4284 (2019-04-05) Min Jin et al.BioMed research international, 2020, 8379358-8379358 (2020-05-29)The petroleum ether (petrol), dichloromethane (CH2Cl2), ethyl acetate (EtOAc), and n-butyl alcohol (n-BuOH) fractions were isolated from alcohol extracts of D. moldavica L. Total phenolic and flavonoid contents and in vitro antioxidant activities of different fractions were evaluated. H9c2 cells... Antiproliferative and apoptotic effect ofIbrahim Turan et al.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 25(2), 241-248 (2017-03-28) A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.Mianli Bian et al.Chemistry (Weinheim an der Bergstrasse, Germany), 26(31), 7092-7108 (2020-02-11) Nanoparticle Delivery of Artesunate Enhances the Anti-tumor Efficiency by Activating Mitochondria-Mediated Cell Apoptosis.Rui Liu et al.Nanoscale research letters, 12(1), 403-403 (2017-06-15) Doxycycline protects against ROS-induced mitochondrial fragmentation and ISO-induced heart failure.Adam Riba et al.PloS one, 12(4), e0175195-e0175195 (2017-04-07) Downregulated miR-150 in bone marrow mesenchymal stem cells attenuates the apoptosis of LPS-stimulated RAW264.7 via MTCH2-dependent mitochondria transfer.Xiao Zhou et al.Biochemical and biophysical research communications, 526(3), 560-567 (2020-04-06) Bafilomycin C1 induces G0/G1 cell-cycle arrest and mitochondrial-mediated apoptosis in human hepatocellular cancer SMMC7721 cells.Xiaoxiao Gao et al.The Journal of antibiotics, 71(9), 808-817 (2018-05-13) Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease.Yong Zhang et al.Biological & pharmaceutical bulletin, 41(5), 670-679 (2018-05-02) Inhibition of PDE4 by FCPR16 induces AMPK-dependent autophagy and confers neuroprotection in SH-SY5Y cells and neurons exposed to MPP+-induced oxidative insult.Jiahong Zhong et al.Free radical biology & medicine, 135, 87-101 (2019-03-01) Femtosecond laser induced photodynamic therapy on 5-ALA treated SKMEL-30 cells: an efficient theranostic strategy to combat melanoma.Meltem Demirel Kars et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 68(5), 657-662 (2014-05-20) Knockdown of KLF11 attenuates hypoxia/reoxygenation injury via JAK2/STAT3 signaling in H9c2.Yang Li et al.Apoptosis : an international journal on programmed cell death, 22(4), 510-518 (2016-11-17) DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis.Hao Zhou et al.Basic research in cardiology, 115(2), 11-11 (2020-01-11) Ca2+/calmodulin-dependent protein kinase II regulation by inhibitor 1 of protein phosphatase 1 alleviates necroptosis in high glucose-induced cardiomyocytes injury.Linlin Sun et al.Biochemical pharmacology, 163, 194-205 (2019-02-20) Mitochondria Regulate the Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth.Hiroki Kato et al.Cell structure and function, 42(2), 105-116 (2017-07-14) Restraint stress of male mice triggers apoptosis in spermatozoa and spermatogenic cells via activating the TNF-α system.Jie Zhang et al.Zygote (Cambridge, England), 1-10 (2020-01-15) The impact of acute thermal stress on green mussel Perna viridis: Oxidative damage and responses.Jing Wang et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 222, 7-15 (2018-04-15) The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro.Jae-Woo Park et al.Acta pharmacologica Sinica, 38(11), 1486-1500 (2017-08-11) T-2 toxin-induced DRP-1-dependent mitophagy leads to the apoptosis of mice Leydig cells (TM3).Jing Wu et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 136, 111082-111082 (2019-12-31) Hispidin induces autophagic and necrotic death in SGC-7901 gastric cancer cells through lysosomal membrane permeabilization by inhibiting tubulin polymerization.Long-Xian Lv et al.Oncotarget, 8(16), 26992-27006 (2017-05-04) MBNL1-Associated Mitochondrial Dysfunction and Apoptosis in C2C12 Myotubes and Mouse Skeletal Muscle.Shingo Yokoyama et al.International journal of molecular sciences, 21(17) (2020-09-06) Ammonium trichloro [1,2-ethanediolato-O,O']-tellurate cures experimental visceral leishmaniasis by redox modulation of Leishmania donovani trypanothione reductase and inhibiting host integrin linked PI3K/Akt pathway.Preeti Vishwakarma et al.Cellular and molecular life sciences : CMLS, 75(3), 563-588 (2017-09-14) Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells.Rong Zhang et al.Cell death & disease, 9(6), 598-598 (2018-05-24) Induction of apoptosis by an oleanolic acid derivative in SMMC-7721 human hepatocellular carcinoma cells is associated with mitochondrial dysfunction.Xinfeng Fan et al.Oncology letters, 15(3), 2821-2828 (2018-02-23) MCL-1 degradation mediated by JNK activation via MEKK1/TAK1-MKK4 contributes to anticancer activity of new tubulin inhibitor MT189.Wei Wang et al.Molecular cancer therapeutics, 13(6), 1480-1491 (2014-04-02) Protective Effect of Baicalein on Oxidative Stress-induced DNA Damage and Apoptosis in RT4-D6P2T Schwann Cells.Cheol Park et al.International journal of medical sciences, 16(1), 8-16 (2019-01-22) Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes.Paloma López de Figueroa et al.Arthritis & rheumatology (Hoboken, N.J.), 67(4), 966-976 (2015-01-22) PM2.5 aggravates the lipid accumulation, mitochondrial damage and apoptosis in macrophage foam cells.Jiangyan Liu et al.Environmental pollution (Barking, Essex : 1987), 249, 482-490 (2019-04-01) Neuroprotective effects of olanzapine against rotenone-induced toxicity in PC12 cells.Ya-Jie Xiong et al.Acta pharmacologica Sinica, 41(4), 508-515 (2020-03-04) Dendritic cells during mousepox: The role of delayed apoptosis in the pathogenesis of infection.Piotr Orlowski et al.Microbial pathogenesis, 109, 99-109 (2017-05-31) Therapeutic efficacy and safety of a human fusion construct targeting the TWEAK receptor Fn14 and containing a modified granzyme B.Ana Alvarez de Cienfuegos et al.Journal for immunotherapy of cancer, 8(2) (2020-09-23) UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer.Jianhua Yu et al.Biochemical pharmacology, 172, 113745-113745 (2019-12-08) Tolerance to dichloroacetonitrile-induced neurotoxicity in streptozotocin-induced diabetic rats.Fang Li et al.Environmental toxicology and pharmacology, 56, 61-67 (2017-09-09) Mito-xenophagic killing of bacteria is coordinated by a metabolic switch in dendritic cells.Nadine Radomski et al.Scientific reports, 7(1), 3923-3923 (2017-06-22) SpBOK inhibits WSSV infection by regulating the apoptotic pathway in mud crab (Scylla paramamosain).Shanmeng Lin et al.Developmental and comparative immunology, 106, 103603-103603 (2020-01-04) Coating doxorubicin-loaded nanocapsules with alginate enhances therapeutic efficacy against Leishmania in hamsters by inducing Th1-type immune responses.S Kansal et al.British journal of pharmacology, 171(17), 4038-4050 (2014-05-20) Ethionine Suppresses Mitochondria Autophagy and Induces Apoptosis via Activation of Reactive Oxygen Species in Neural Tube Defects.Li Zhang et al.Frontiers in neurology, 11, 242-242 (2020-04-23) Baicalin Induces Apoptotic Death of Human Chondrosarcoma Cells through Mitochondrial Dysfunction and Downregulation of the PI3K/Akt/mTOR Pathway.Minyu Zhu et al.Planta medica, 85(5), 360-369 (2018-11-24) PDE5 inhibitor protects the mitochondrial function of hypoxic myocardial cells.Haiyan Jia et al.Experimental and therapeutic medicine, 17(1), 199-204 (2019-01-18) High glucose induces the apoptosis of HUVECs in mitochondria dependent manner by enhancing VDAC1 expression.Jia Zhang et al.Die Pharmazie, 73(12), 725-728 (2018-12-14) A Helical Polypeptide-Based Potassium Ionophore Induces Endoplasmic Reticulum Stress-Mediated Apoptosis by Perturbing Ion Homeostasis.DaeYong Lee et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(14), 1801995-1801995 (2019-08-06) Induction of Apoptosis by Citrus unshiu Peel in Human Breast Cancer MCF-7 Cells: Involvement of ROS-Dependent Activation of AMPK.Min Yeong Kim et al.Biological & pharmaceutical bulletin, 41(5), 713-721 (2018-05-02) Genipin protects rats against lipopolysaccharide-induced acute lung injury by reinforcing autophagy.Zhijie Zhang et al.International immunopharmacology, 72, 21-30 (2019-04-09) Potentiation of in Vivo Anticancer Efficacy of Selenium Nanoparticles by Mushroom Polysaccharides Surface Decoration.Delong Zeng et al.Journal of agricultural and food chemistry, 67(10), 2865-2876 (2019-02-21) Computational flow cytometry reveals that cryopreservation induces spermptosis but subpopulations of spermatozoa may experience capacitation-like changes.C Ortega-Ferrusola et al.Reproduction (Cambridge, England), 153(3), 293-304 (2016-12-15) SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway.Meng Zhang et al.Aging and disease, 9(2), 273-286 (2018-06-14) Oxidative Damage of Blood Platelets Correlates with the Degree of Psychophysical Disability in Secondary Progressive Multiple Sclerosis.Angela Dziedzic et al.Oxidative medicine and cellular longevity, 2020, 2868014-2868014 (2020-07-14) Host defense peptide Hymenochirin-1B induces lung cancer cell apoptosis and cell cycle arrest through the mitochondrial pathway.Yihan Zhang et al.Biochemical and biophysical research communications, 512(2), 269-275 (2019-03-20) Stepwise dual targeting and dual responsive polymer micelles for mitochondrion therapy.Xiaobin Zhang et al.Journal of controlled release : official journal of the Controlled Release Society, 322, 157-169 (2020-03-15) ZnPP reduces autophagy and induces apoptosis, thus aggravating liver ischemia/reperfusion injury in vitro.Yun Wang et al.International journal of molecular medicine, 34(6), 1555-1564 (2014-10-17) Lactoferricin B like peptide triggers mitochondrial disruption-mediated apoptosis by inhibiting respiration under nitric oxide accumulation in Candida albicans.Suhyun Kim et al.IUBMB life, 72(7), 1515-1527 (2020-04-09) Arctigenin induces the apoptosis of primary effusion lymphoma cells under conditions of glucose deprivation.Yusuke Baba et al.International journal of oncology, 52(2), 505-517 (2017-12-06) Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity.Hongshun Wang et al.Cell death & disease, 10(9), 627-627 (2019-08-21) Chronic hyper-leptinemia induces insulin signaling disruption in adipocytes: Implications of NOS2.Abhishek Gupta et al.Free radical biology & medicine, 112, 93-108 (2017-07-26) Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.Ahmi Öz et al.Molecular membrane biology, 33(3-5), 76-88 (2017-06-02) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain.Lucie Valek et al.Redox biology, 11, 176-191 (2016-12-16) Prolonged treatment with mevalonolactone induces oxidative stress response with reactive oxygen species production, mitochondrial depolarization and inflammation in human glioblastoma U-87 MG cells.Rossella Gratton et al.Neurochemistry international, 120, 233-237 (2018-05-13) Evaluation of the water disinfection by-product dichloroacetonitrile-induced biochemical, oxidative, histopathological, and mitochondrial functional alterations: Subacute oral toxicity in rats.Ying Dong et al.Toxicology and industrial health, 34(3), 158-168 (2017-12-12) Effects of N-butylphthalide on the activation of Keap1/Nrf-2 signal pathway in rats after carbon monoxide poisoning.Qin Li et al.Environmental toxicology and pharmacology, 40(1), 22-29 (2015-06-10) Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling.Minjing Ke et al.Cell death & disease, 11(2), 130-130 (2020-02-20) Anti-Proliferative Properties and Proapoptotic Function of New CB2 Selective Cannabinoid Receptor Agonist in Jurkat Leukemia Cells.Antonella Capozzi et al.International journal of molecular sciences, 19(7) (2018-07-06) Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway.Zhiwen Zeng et al.Redox biology, 12, 625-633 (2017-04-10) Curcumin Alleviates β Amyloid-Induced Neurotoxicity in HT22 Cells via Upregulating SOD2.Shuping Du et al.Journal of molecular neuroscience : MN, 67(4), 540-549 (2019-02-13) Perioperative dynamics and significance of amino acid profiles in patients with cancer.Yu Gu et al.Journal of translational medicine, 13, 35-35 (2015-01-28) Effect of mitochondrial calcium uniporter blocking on human spermatozoa.A Bravo et al.Andrologia, 47(6), 662-668 (2014-07-26) PINK1 regulates mitochondrial morphology via promoting mitochondrial fission in porcine preimplantation embryos.Ying-Jie Niu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(7), 7882-7895 (2019-03-22) AMPK activation ameliorates Alzheimer's disease-like pathology and spatial memory impairment in a streptozotocin-induced Alzheimer's disease model in rats.Lai-Ling Du et al.Journal of Alzheimer's disease : JAD, 43(3), 775-784 (2014-08-13) Helichrysetin Induces DNA Damage that Triggers JNK-Mediated Apoptosis in Ca Ski Cells.Ho Yen Fong et al.Pharmacognosy magazine, 13(52), 607-612 (2017-12-05) Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation.Luc H Boudreau et al.Blood, 124(14), 2173-2183 (2014-08-02) Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.Shuang Li et al.Cell & bioscience, 9, 1-1 (2019-01-10) The Effects of Different Fluorescent Indicators in Observing the Changes of the Mitochondrial Membrane Potential during Oxidative Stress-Induced Mitochondrial Injury of Cardiac H9c2 Cells.Yahan Sun et al.Journal of fluorescence, 30(6), 1421-1430 (2020-09-17) Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC‑27.Yingwei Sun et al.Molecular medicine reports, 22(4), 2826-2832 (2020-09-19) Rapamycin enhances growth inhibition on urothelial carcinoma cells through LKB1 deficiency-mediated mitochondrial dysregulation.Young Mi Whang et al.Journal of cellular physiology, 234(8), 13083-13096 (2018-12-15) Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway.Pengyun Li et al.Expert opinion on therapeutic targets, 19(7), 997-1010 (2015-06-16) Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication.Philippe Haouzi et al.Clinical toxicology (Philadelphia, Pa.), 56(9), 828-840 (2018-02-17) Protective Effect of Edaravone Against Aβ25-35-Induced Mitochondrial Oxidative Damage in SH-SY5Y Cells.G-L Zhang et al.Cellular and molecular biology (Noisy-le-Grand, France), 63(5), 36-42 (2017-07-19) Near-Infrared Spectroscopy Screening to Allow Detection of Pathogenic Mitochondrial DNA Variants in Individuals with Unexplained Abnormal Fatigue: A Preliminary Study.Bert M Celie et al.Applied spectroscopy, 72(5), 715-724 (2018-01-18) Study on the potential way of hepatic cytotoxicity of N,N-dimethylformamide.Shiqing Li et al.Journal of biochemical and molecular toxicology, 32(9), e22190-e22190 (2018-07-10) Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells.Lin Zhao et al.PloS one, 10(6), e0128502-e0128502 (2015-06-02) In vitro PAMAM, phosphorus and viologen-phosphorus dendrimers prevent rotenone-induced cell damage.Katarzyna Milowska et al.International journal of pharmaceutics, 474(1-2), 42-49 (2014-08-12) Danqi Pill Protects Against Heart Failure Post-Acute Myocardial Infarction via HIF-1α/PGC-1α Mediated Glucose Metabolism Pathway.Qian Zhang et al.Frontiers in pharmacology, 11, 458-458 (2020-05-07) The WT1/MVP-Mediated Stabilization on mTOR/AKT Axis Enhances the Effects of Cisplatin in Non-small Cell Lung Cancer by a Reformulated Yu Ping Feng San Herbal Preparation.Jian-Shu Lou et al.Frontiers in pharmacology, 9, 853-853 (2018-08-23) Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress.Changwon Yang et al.Cancer letters, 399, 10-19 (2017-04-22) Induction of G2/M Phase Arrest by Diosgenin via Activation of Chk1 Kinase and Cdc25C Regulatory Pathways to Promote Apoptosis in Human Breast Cancer Cells.Wen-Ling Liao et al.International journal of molecular sciences, 21(1) (2019-12-29) Characteristics and Possible Role of Bovine Sperm Head-to-Head Agglutination.Kohei Umezu et al.Cells, 9(8) (2020-08-14) MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1.Qing Xie et al.Oncotarget, 8(13), 22003-22013 (2017-04-21) Mechanisms of TiO2 nanoparticle-induced neuronal apoptosis in rat primary cultured hippocampal neurons.Lei Sheng et al.Journal of biomedical materials research. Part A, 103(3), 1141-1149 (2014-07-22) Lian Liu et al.Neural regeneration research, 15(8), 1526-1531 (2020-01-31)The accumulation of excessive reactive oxygen species can exacerbate any injury of retinal tissue because free radicals can trigger lipid peroxidation, protein damage and DNA fragmentation. Increased oxidative stress is associated with the common pathological process of many eye diseases... Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.Xuan Chen et al.British journal of cancer, 123(1), 126-136 (2020-05-06) Transferrin-conjugated liposomes loaded with novel dihydroquinoline derivatives as potential anticancer agents.Mengqiao Wang et al.PloS one, 12(10), e0186821-e0186821 (2017-11-01) Apolipoprotein O expression in mouse liver enhances hepatic lipid accumulation by impairing mitochondrial function.Feng Tian et al.Biochemical and biophysical research communications, 491(1), 8-14 (2017-06-26) MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.Guo-Xing Wan et al.Cardiovascular toxicology, 19(3), 264-275 (2018-12-12) Cytotoxic Effects of Zoom® Whitening Product in Human Fibroblasts.Carlos Miguel Marto et al.Materials (Basel, Switzerland), 13(7) (2020-03-29) Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo.Hyo Geun Kim et al.Journal of ethnopharmacology, 171, 196-204 (2015-06-13) Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death.Sainan Li et al.British journal of cancer, 117(10), 1518-1528 (2017-09-20) JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer.Haifeng Qiu et al.Oncotarget, 6(9), 6915-6930 (2015-03-13) Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells.Jing-Jing Mou et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 729-737 (2018-04-24) Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells.Kun-Lin Chen et al.In vitro cellular & developmental biology. Animal, 56(4), 322-331 (2020-05-08) Aloin Protects Against Blood-Brain Barrier Damage After Traumatic Brain Injury in Mice.Yao Jing et al.Neuroscience bulletin, 36(6), 625-638 (2020-02-27) miRNA-mRNA crosstalk in myocardial ischemia induced by calcified aortic valve stenosis.Chenyang Duan et al.Aging, 11(2), 448-466 (2019-01-18) Exogenous H2S Protects Against Diabetic Cardiomyopathy by Activating Autophagy via the AMPK/mTOR Pathway.Fan Yang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(3), 1168-1187 (2017-10-05) New chalcone-type compounds and 2-pyrazoline derivatives: synthesis and caspase-dependent anticancer activity.Mohamed I Chouiter et al.Future medicinal chemistry, 12(6), 493-509 (2020-02-27) Zinc oxide nanoparticles induce human tenon fibroblast apoptosis through reactive oxygen species and caspase signaling pathway.Ling Wang et al.Archives of biochemistry and biophysics, 683, 108324-108324 (2020-03-01) Suppressed de novo lipogenesis by plasma membrane citrate transporter inhibitor promotes apoptosis in HepG2 cells.Phornpun Phokrai et al.FEBS open bio, 8(6), 986-1000 (2018-06-22) MCL-1 Is a Key Determinant of Breast Cancer Cell Survival: Validation of MCL-1 Dependency Utilizing a Highly Selective Small Molecule Inhibitor.Yu Xiao et al.Molecular cancer therapeutics, 14(8), 1837-1847 (2015-05-28) Curcumin pretreatment prevents hydrogen peroxide-induced oxidative stress through enhanced mitochondrial function and deactivation of Akt/Erk signaling pathways in rat bone marrow mesenchymal stem cells.Xujie Wang et al.Molecular and cellular biochemistry, 443(1-2), 37-45 (2017-10-21) Cell type-dependent effects of ellagic acid on cellular metabolism.Alexandra L Boehning et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 106, 411-418 (2018-07-11) A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration.Huiliang Zhang et al.Cardiovascular research, 113(2), 160-170 (2016-10-31) Targeting ferroptosis contributes to ATPR-induced AML differentiation via ROS-autophagy-lysosomal pathway.Yan Du et al.Gene, 755, 144889-144889 (2020-06-14) Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease.Jun Kai et al.Free radical biology & medicine, 153, 89-102 (2020-04-15) Fluorene-9-bisphenol exposure induces cytotoxicity in mouse oocytes and causes ovarian damage.Zhenzhen Jia et al.Ecotoxicology and environmental safety, 180, 168-178 (2019-05-15) The iron-sulfur protein subunit of succinate dehydrogenase is critical in driving mitochondrial reactive oxygen species generation in Apostichopus japonicus.Lianlian Sun et al.Fish & shellfish immunology, 102, 350-360 (2020-05-07) Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy.Kevin Yang et al.Scientific reports, 7(1), 10501-10501 (2017-09-07) Heat-shock protein A8 restores sperm membrane integrity by increasing plasma membrane fluidity.Najmeh Moein-Vaziri et al.Reproduction (Cambridge, England), 147(5), 719-732 (2014-02-07) Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.Xinyu Tang et al.Oncology reports, 43(2), 591-600 (2020-01-03) Alpha-linolenic acid protects the developmental capacity of bovine cumulus-oocyte complexes matured under lipotoxic conditions in vitro.Waleed F A Marei et al.Biology of reproduction, 96(6), 1181-1196 (2017-05-19) Apoptotic and antimetastatic activities of betulin isolated from Quercus incana against non-small cell lung cancer cells.Binte Zehra et al.Cancer management and research, 11, 1667-1683 (2019-03-14) Methamidophos alters sperm function and DNA at different stages of spermatogenesis in mice.Mayrut Urióstegui-Acosta et al.Toxicology and applied pharmacology, 279(3), 391-400 (2014-07-08) The detrimental effects of glucocorticoids exposure during pregnancy on offspring's cardiac functions mediated by hypermethylation of bone morphogenetic protein-4.Jieying Peng et al.Cell death & disease, 9(8), 834-834 (2018-08-08) Deferoxamine Treatment Combined With Sevoflurane Postconditioning Attenuates Myocardial Ischemia-Reperfusion Injury by Restoring HIF-1/BNIP3-Mediated Mitochondrial Autophagy in GK Rats.Long Yang et al.Frontiers in pharmacology, 11, 6-6 (2020-03-07) Reproductive Toxicity of Endosulfan: Implication From Germ Cell Apoptosis Modulated by Mitochondrial Dysfunction and Genotoxic Response Genes in Caenorhabditis elegans.Hua Du et al.Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 118-127 (2015-02-11) Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer.Anna Tankiewicz-Kwedlo et al.International journal of molecular sciences, 19(4) (2018-04-25) Bone marrow mesenchymal stem cells-derived conditioned medium protects cardiomyocytes from hypoxia/reoxygenation-induced injury through Notch2/mTOR/autophagy signaling.Xianyu Li et al.Journal of cellular physiology, 234(10), 18906-18916 (2019-04-07) Plasma and mitochondrial membrane perturbation induced by aluminum in human peripheral blood lymphocytes.Aliaksandra Sergeevna Skarabahatava et al.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 31, 37-44 (2015-05-26) A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway.Pranjal Sarma et al.Cancer biology & therapy, 15(10), 1320-1332 (2014-07-11) 3, 3'-Dimethylquercetin Inhibits the Proliferation of Human Colon Cancer RKO Cells through Inducing G2/M Cell Cycle Arrest and Apoptosis.Jianguo Wu et al.Anti-cancer agents in medicinal chemistry, 19(3), 402-409 (2018-11-07) The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.Kunpeng Wu et al.Blood, 136(4), 501-515 (2020-04-16) Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention.Beverly A Baptiste et al.Free radical biology & medicine, 124, 149-162 (2018-06-08) The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.Sara Mirali et al.Science translational medicine, 12(538) (2020-04-10) Peptide-Au Clusters Induced Tumor Cells Apoptosis via Targeting Glutathione Peroxidase-1: The Molecular Dynamics Assisted Experimental Studies.Meiqing Liu et al.Scientific reports, 7(1), 131-131 (2017-03-10) Diquat-induced oxidative stress increases intestinal permeability, impairs mitochondrial function, and triggers mitophagy in piglets.Shuting Cao et al.Journal of animal science, 96(5), 1795-1805 (2018-03-22) Fucoxanthin Protects against oxLDL-Induced Endothelial Damage via Activating the AMPK-Akt-CREB-PGC1α Pathway.Hsiu-Chung Ou et al.Molecular nutrition & food research, 63(10), e1801353-e1801353 (2019-03-21) Synergistic Inactivation Mechanism of Combined Plasma-Activated Water and Mild Heat against Saccharomyces cerevisiae.Rong Zhang et al.Journal of food protection, 83(8), 1307-1314 (2020-04-16) Diphlorethohydroxycarmalol Attenuates Fine Particulate Matter-Induced Subcellular Skin Dysfunction.Ao Xuan Zhen et al.Marine drugs, 17(2) (2019-02-06) Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke.Chuanhong Wu et al.British journal of pharmacology, 176(3), 400-415 (2018-11-11) Carboxylic Acid Fullerene (C60) Derivatives Attenuated Neuroinflammatory Responses by Modulating Mitochondrial Dynamics.Shefang Ye et al.Nanoscale research letters, 10(1), 953-953 (2015-06-11) Dose rate effects of low-LET ionizing radiation on fish cells.Nguyen T K Vo et al.Radiation and environmental biophysics, 56(4), 433-441 (2017-08-07) Downregulation of AIF-2 Inhibits Proliferation, Migration, and Invasion of Human Glioma Cells via Mitochondrial Dysfunction.Wei Chen et al.Journal of molecular neuroscience : MN, 68(2), 304-310 (2019-04-15) A mechanism by which Astragalus polysaccharide protects against ROS toxicity through inhibiting the protein dephosphorylation of boar sperm preserved at 4 °C.Jieli Fu et al.Journal of cellular physiology, 233(7), 5267-5280 (2017-12-13) Saikosaponin D acts against corticosterone-induced apoptosis via regulation of mitochondrial GR translocation and a GR-dependent pathway.Zong-Yang Li et al.Progress in neuro-psychopharmacology & biological psychiatry, 53, 80-89 (2014-03-19) PINK1-Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B-Mediated Hippo-YAP/TAZ Pathway.Shengjun Fan et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(5), 1900860-1900860 (2020-03-11) Eclalbasaponin I causes mitophagy to repress oxidative stress-induced apoptosis via activation of p38 and ERK in SH-SY5Y cells.Wei Wang et al.Free radical research, 53(6), 655-668 (2019-06-13) Protective effect of cyclosporine A in the treatment of severe hydronephrosis in a rabbit renal pelvic perfusion modelBen-Zheng Zhou et al.Turkish journal of medical sciences, 49(5), 1590-1598 (2019-10-28) Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.Siti Nur Fadzilah Muhsain et al.Toxicology and applied pharmacology, 282(1), 77-89 (2014-12-06) MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation.Jun Zheng et al.Cell death & disease, 11(4), 256-256 (2020-04-22) Autoantibody against β1-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4+ T cells by up-regulating AMPK-mediated fatty acid oxidation.Wenli Xu et al.Cell death & disease, 10(3), 158-158 (2019-02-17) Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis.Guiwen Ye et al.Cell death & disease, 11(9), 775-775 (2020-09-19) Enzymatic Synthesis of Anabolic Steroid Glycosides by Glucosyltransferase from Terribacillus sp. PAMC 23288.Eun-Ji Yu et al.Journal of microbiology and biotechnology, 30(4), 604-614 (2020-01-03) Neurotoxicity induced by methamphetamine-heroin combination in PC12 cells.Xiang Tian et al.Neuroscience letters, 647, 1-7 (2017-03-10) Pyropheophorbide-α methyl ester-mediated photodynamic therapy induces apoptosis and inhibits LPS-induced inflammation in RAW264.7 macrophages.Liyi Huang et al.Photodiagnosis and photodynamic therapy, 25, 148-156 (2018-12-19) 14-3-3ζ Regulates the Platelet Apoptosis During Storage.Yuzhong Yan et al.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 36(2), 324-329 (2020-05-20) Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis.Mayumi Watanabe et al.Toxicology, 322, 43-50 (2014-05-08) In vitro activities of hexaazatrinaphthylenes against Leishmania spp.Atteneri López-Arencibia et al.Antimicrobial agents and chemotherapy, 59(5), 2867-2874 (2015-03-11) Oltipraz Prevents High Glucose-Induced Oxidative Stress and Apoptosis in RSC96 Cells through the Nrf2/NQO1 Signalling Pathway.Zengxin Jiang et al.BioMed research international, 2020, 5939815-5939815 (2020-07-21) Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway.Mengzhao Zhang et al.Chemico-biological interactions, 292, 65-75 (2018-07-10) SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules.Fang Wang et al.Molecular cancer therapeutics, 17(4), 763-775 (2018-04-04) Senkyunolide H protects against MPP+-induced apoptosis via the ROS-mediated mitogen-activated protein kinase pathway in PC12 cells.Yanyan Luo et al.Environmental toxicology and pharmacology, 65, 73-81 (2018-12-24) "Funny" channels in cardiac mitochondria modulate membrane potential and oxygen consumption.Teresa Padilla-Flores et al.Biochemical and biophysical research communications, 524(4), 1030-1036 (2020-02-18) Calenduloside E Analogues Protecting H9c2 Cardiomyocytes Against HYu Tian et al.Frontiers in pharmacology, 8, 862-862 (2017-12-09) Metformin treatment of high-fat diet-fed obese male mice restores sperm function and fetal growth, without requiring weight loss.Nicole O McPherson et al.Asian journal of andrology, 22(6), 560-568 (2020-02-27) CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice.Stephen Gilmore-Hall et al.The Journal of cell biology, 218(1), 206-219 (2018-10-20) Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts.Salik Hussain et al.Particle and fibre toxicology, 11, 28-28 (2014-06-12) Mitochondrial Dysfunction and Altered Renal Metabolism in Dahl Salt-Sensitive Rats.Zhengjun Wang et al.Kidney & blood pressure research, 42(3), 587-597 (2017-09-19) Low doses of BPA induced abnormal mitochondrial fission and hypertrophy in human embryonic stem cell-derived cardiomyocytes via the calcineurin-DRP1 signaling pathway: A comparison between XX and XY cardiomyocytes.Wei Cheng et al.Toxicology and applied pharmacology, 388, 114850-114850 (2019-12-13) Efficient induction of apoptosis in cancer cells by paclitaxel-loaded selenium nanoparticles.Anil Parsram Bidkar et al.Nanomedicine (London, England), 12(21), 2641-2651 (2017-10-19) Identification of two mitochondrial-targeting cyclometalated iridium(III) complexes as potent anti-glioma stem cells agents.Wan Peng et al.Journal of inorganic biochemistry, 203, 110909-110909 (2019-11-07) Metabolic pathways underlying GATA6 regulating Trastuzumab resistance in Gastric Cancer cells based on untargeted metabolomics.Jinxia Chang et al.International journal of medical sciences, 17(18), 3146-3164 (2020-11-12) Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation.Dan Liu et al.The international journal of biochemistry & cell biology, 57, 7-19 (2014-10-05) Oxicam-derived non-steroidal anti-inflammatory drugs suppress 1-methyl-4-phenyl pyridinium-induced cell death via repression of endoplasmic reticulum stress response and mitochondrial dysfunction in SH-SY5Y cells.Tomohiro Omura et al.Biochemical and biophysical research communications, 503(4), 2963-2969 (2018-08-16) Effect of various selenium doses on chromium(IV)-induced nephrotoxicity in a male chicken model.Huiyu Wan et al.Chemosphere, 174, 306-314 (2017-02-10) Mitochondrial unfolded protein response gene CLPP changes mitochondrial dynamics and affects mitochondrial function.GuiJun Wu et al.PeerJ, 7, e7209-e7209 (2019-07-16) ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome.Claire Angebault et al.Science signaling, 11(553) (2018-10-26) p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells.Nittiya Chowchaikong et al.International journal of oncology, 52(6), 2031-2040 (2018-04-06) CircPRKCI-miR-545/589-E2F7 axis dysregulation mediates hydrogen peroxide-induced neuronal cell injury.Qiantao Cheng et al.Biochemical and biophysical research communications, 514(2), 428-435 (2019-05-06) Effects of ammonia nitrogen on gill mitochondria in clam Ruditapes philippinarum.Ming Cong et al.Environmental toxicology and pharmacology, 65, 46-52 (2018-12-12) Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy.Bin Zhang et al.Scientific reports, 7, 44239-44239 (2017-03-14) Laurinterol from Laurencia johnstonii eliminates Naegleria fowleri triggering PCD by inhibition of ATPases.Iñigo Arberas-Jiménez et al.Scientific reports, 10(1), 17731-17731 (2020-10-22) Benzoxazole Derivative K313 Induces Cell Cycle Arrest, Apoptosis and Autophagy Blockage and Suppresses mTOR/p70S6K Pathway in Nalm-6 and Daudi Cells.Wenying Zhong et al.Molecules (Basel, Switzerland), 25(4) (2020-02-27) Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson's Disease.Xiaojuan Han et al.Frontiers in neuroscience, 12, 397-397 (2018-07-04) Combination of Mitochondrial and Plasma Membrane Citrate Transporter Inhibitors Inhibits De Novo Lipogenesis Pathway and Triggers Apoptosis in Hepatocellular Carcinoma Cells.Wan-Angkan Poolsri et al.BioMed research international, 2018, 3683026-3683026 (2018-03-17) Aloe-emodin Induces Apoptosis in Human Liver HL-7702 Cells through Fas Death Pathway and the Mitochondrial Pathway by Generating Reactive Oxygen Species.Xiaoxv Dong et al.Phytotherapy research : PTR, 31(6), 927-936 (2017-04-27) Singly protonated dehydronorcantharidin silver coordination polymer induces apoptosis of lung cancer cells via reactive oxygen species-mediated mitochondrial pathway.Senpeng Li et al.European journal of medicinal chemistry, 86, 1-11 (2014-08-20) Ziyuglycoside II induces caspases-dependent and caspases-independent apoptosis in human colon cancer cells.Khaliunaa Lkhagvasuren et al.Toxicology in vitro : an international journal published in association with BIBRA, 59, 255-262 (2019-04-29) Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration.Daoliang Xu et al.Pharmacological research, 117, 357-369 (2017-01-15) PEDF improves mitochondrial function in RPE cells during oxidative stress.Yuan He et al.Investigative ophthalmology & visual science, 55(10), 6742-6755 (2014-09-13) Cyanidin-3-O-glucoside promotes progesterone secretion by improving cells viability and mitochondrial function in cadmium-sulfate-damaged R2C cells.Xia Li et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 128, 97-105 (2019-03-28) A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.Lina Zhang et al.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 60, 126493-126493 (2020-03-18) Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection.Dejian Dang et al.Oncotarget, 8(46), 81014-81026 (2017-11-09) Triptolide induces p53-dependent cardiotoxicity through mitochondrial membrane permeabilization in cardiomyocytes.Yue Xi et al.Toxicology and applied pharmacology, 355, 269-285 (2018-07-17) Thioridazine Sensitizes Cisplatin Against Chemoresistant Human Lung and Ovary Cancer Cells.Guanhua Qian et al.DNA and cell biology, 38(7), 718-724 (2019-06-13) Amplification of Oxidative Stress in MCF-7 Cells by a Novel pH-Responsive Amphiphilic Micellar System Enhances Anticancer Therapy.Kai Dong et al.Molecular pharmaceutics, 16(2), 689-700 (2019-01-03) Deletion of mammalian sterile 20-like kinase 1 attenuates neuronal loss and improves locomotor function in a mouse model of spinal cord trauma.Pan-Feng Wang et al.Molecular and cellular biochemistry, 431(1-2), 11-20 (2017-02-18) Non-thermal plasma induces mitochondria-mediated apoptotic signaling pathway via ROS generation in HeLa cells.Wei Li et al.Archives of biochemistry and biophysics, 633, 68-77 (2017-09-13) Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation.P Picone et al.Free radical research, 48(12), 1397-1408 (2014-09-03) SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress.Sanjukta Guha et al.Scientific reports, 7(1), 4074-4074 (2017-06-24) Gefitinib Enhances Mitochondrial Biological Functions in NSCLCs withTomoya Takenaka et al.Anticancer research, 37(9), 4779-4788 (2017-09-06) Inclusion complex from cyclodextrin-grafted hyaluronic acid and pseudo protein as biodegradable nano-delivery vehicle for gambogic acid.Ying Ji et al.Acta biomaterialia, 62, 234-245 (2017-09-02) Arenobufagin Inhibits the Phosphatidylinositol 3-kinase/Protein Kinase B/Mammalian Target of Rapamycin Pathway and Induces Apoptosis and Autophagy in Pancreatic Cancer Cells.Xiaolu Wei et al.Pancreas, 49(2), 261-272 (2020-02-06) Cellular evaluation of diselenonicotinamide (DSNA) as a radioprotector against cell death and DNA damage.M Raghuraman et al.Metallomics : integrated biometal science, 9(6), 715-725 (2017-05-16) Tebuconazole and Econazole Act Synergistically in Mediating Mitochondrial Stress, Energy Imbalance, and Sequential Activation of Autophagy and Apoptosis in Mouse Sertoli TM4 Cells: Possible Role of AMPK/ULK1 Axis.Sabrina Petricca et al.Toxicological sciences : an official journal of the Society of Toxicology, 169(1), 209-223 (2019-01-31) SRV2 promotes mitochondrial fission and Mst1-Drp1 signaling in LPS-induced septic cardiomyopathy.Xiuling Shang et al.Aging, 12(2), 1417-1432 (2020-01-18) Arachidonic Acid Attenuates Cell Proliferation, Migration and Viability by a Mechanism Independent on Calcium Entry.Carlos Cantonero et al.International journal of molecular sciences, 21(9) (2020-05-13) New benzimidazole-derived isothioureas as potential antileukemic agents--studies in vitro.Mirosława Koronkiewicz et al.Medicinal chemistry (Shariqah (United Arab Emirates)), 11(4), 364-372 (2014-12-04) Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.Xiaolong Xu et al.Theranostics, 9(8), 2252-2267 (2019-06-01) A semisynthetic borrelidin analogue BN-3b exerts potent antifungal activity against Candida albicans through ROS-mediated oxidative damage.Hao Su et al.Scientific reports, 10(1), 5081-5081 (2020-03-21) Aqueous extract of Cortex Dictamni protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress and apoptosis by PI3K/Akt signaling pathway.Lin Li et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 89, 233-244 (2017-02-24) Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth.Xia Li et al.Oncogene, 37(18), 2469-2480 (2018-02-20) Candidates for reproductive biomarkers: Protein phosphorylation and acetylation positively related to selected parameters of boar spermatozoa quality.Peifei Li et al.Animal reproduction science, 197, 67-80 (2018-08-26) Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK.Xianling Gong et al.BMC cancer, 18(1), 578-578 (2018-05-23) H2S protects PC12 cells against toxicity of corticosterone by modulation of BDNF-TrkB pathway.Shenglan Gao et al.Acta biochimica et biophysica Sinica, 47(11), 915-924 (2015-10-02) SERPINB1 ameliorates acute lung injury in liver transplantation through ERK1/2-mediated STAT3-dependent HO-1 induction.Weifeng Yao et al.Free radical biology & medicine, 108, 542-553 (2017-04-22) Calcium and oxidative stress mediate perillaldehyde-induced apoptosis in Candida albicans.Hui Tian et al.Applied microbiology and biotechnology, 101(8), 3335-3345 (2017-02-23) Alterations in macrophage phagocytosis and inflammatory tone following exposure to the organochlorine compounds oxychlordane and trans-nonachlor.Darian Young et al.Toxicology in vitro : an international journal published in association with BIBRA, 65, 104791-104791 (2020-02-15) Knockdown of PLAT enhances the anticancer effect of gefitinib in non-small cell lung cancer.Mengnan Yan et al.Journal of thoracic disease, 12(3), 712-723 (2020-04-11) Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway.Cheol Park et al.Animal cells and systems, 24(1), 60-68 (2020-03-12) Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways.Xia Han et al.Biomolecules & therapeutics, 27(1), 41-47 (2018-06-22) Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.Xiaochun Yang et al.Anatomical record (Hoboken, N.J. : 2007), 298(2), 386-395 (2014-07-22) The influence of SRPK1 on glioma apoptosis, metastasis, and angiogenesis through the PI3K/Akt signaling pathway under normoxia.Yingwei Chang et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(8), 6083-6093 (2015-04-03) A miRNA-101-3p/Bim axis as a determinant of serum deprivation-induced endothelial cell apoptosis.Ji-Hee Kim et al.Cell death & disease, 8(5), e2808-e2808 (2017-05-19) Calcium sensing receptor initiating cystathionine-gamma-lyase/hydrogen sulfide pathway to inhibit platelet activation in hyperhomocysteinemia rat.Yuwen Wang et al.Experimental cell research, 358(2), 171-181 (2017-06-22) Hepatitis C virus p7 induces mitochondrial depolarization of isolated liver mitochondria.Deok-Gyun You et al.Molecular medicine reports, 16(6), 9533-9538 (2017-10-19) Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria.Xiaofei Wang et al.Ecotoxicology and environmental safety, 195, 110408-110408 (2020-03-18) Stress-associated endoplasmic reticulum protein 1 (SERP1) and Atg8 synergistically regulate unfolded protein response (UPR) that is independent on autophagy in Candida albicans.Jianrong Li et al.International journal of medical microbiology : IJMM, 308(3), 378-386 (2018-03-17) Huanhuan Lv et al.Oxidative medicine and cellular longevity, 2020, 5021983-5021983 (2020-04-24)Osteosarcoma is the most common primary malignancy of the skeleton in children and adults. The outcomes of people with osteosarcomas are unsatisfied. β-Phenethyl isothiocyanate (PEITC) exhibits chemoprevention and chemotherapeutic activities against many human cancers. The molecular mechanism underlying its action... Ethanolic extract of Cordyceps cicadae exerts antitumor effect on human gastric cancer SGC-7901 cells by inducing apoptosis, cell cycle arrest and endoplasmic reticulum stress.Hongqing Xie et al.Journal of ethnopharmacology, 231, 230-240 (2018-11-24) Soluble LRIG2 ectodomain is released from glioblastoma cells and promotes the proliferation and inhibits the apoptosis of glioblastoma cells in vitro and in vivo in a similar manner to the full-length LRIG2.Qungen Xiao et al.PloS one, 9(10), e111419-e111419 (2014-10-30) Targeting Cell Necroptosis and Apoptosis Induced by Shikonin via Receptor Interacting Protein Kinases in Estrogen Receptor Positive Breast Cancer Cell Line, MCF-7.Zahra Shahsavari et al.Anti-cancer agents in medicinal chemistry, 18(2), 245-254 (2017-09-22) Antimalarial drug artesunate is effective against chemoresistant anaplastic thyroid carcinoma via targeting mitochondrial metabolism.Ling Ma et al.Journal of bioenergetics and biomembranes, 52(2), 123-130 (2020-02-10) Tanshinone IIA Protects Hippocampal Neuronal Cells from Reactive Oxygen Species Through Changes in Autophagy and Activation of Phosphatidylinositol 3-Kinase, Protein Kinas B, and Mechanistic Target of Rapamycin Pathways.Yingchun Zhu et al.Current neurovascular research, 14(2), 132-140 (2017-03-07) Particulate Matter 2.5 Mediates Cutaneous Cellular Injury by Inducing Mitochondria-Associated Endoplasmic Reticulum Stress: Protective Effects of Ginsenoside Rb1.Mei Jing Piao et al.Antioxidants (Basel, Switzerland), 8(9) (2019-09-12) Attenuation of ER stress prevents post-infarction-induced cardiac rupture and remodeling by modulating both cardiac apoptosis and fibrosis.Tao Luo et al.Chemico-biological interactions, 225, 90-98 (2014-12-03) Characterization of lactic acid bacteria derived exopolysaccharides for use as a defined neuroprotective agent against amyloid beta1-42-induced apoptosis in SH-SY5Y cells.Seda Sirin et al.Scientific reports, 10(1), 8124-8124 (2020-05-18) Cold atmospheric plasma induces apoptosis of melanoma cells via Sestrin2-mediated nitric oxide synthase signaling.Jun Xia et al.Journal of biophotonics, 12(1), e201800046-e201800046 (2018-06-23) Antistarvation Strategies of E. Sinensis: Regulatory Networks under Hepatopancreas Consumption.Xiaoli Huang et al.Oxidative medicine and cellular longevity, 2020, 6085343-6085343 (2020-04-08) Stomatin-like protein 2 (SLP2) regulates the proliferation and invasion of trophoblast cells by modulating mitochondrial functions.Xue Zhang et al.Placenta, 100, 13-23 (2020-08-20) Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease.Gulam Haji et al.Respiratory research, 21(1), 262-262 (2020-10-14) Loading MiR-210 in Endothelial Progenitor Cells Derived Exosomes Boosts Their Beneficial Effects on Hypoxia/Reoxygeneation-Injured Human Endothelial Cells via Protecting Mitochondrial Function.Xiaotang Ma et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 46(2), 664-675 (2018-04-06) Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.Muhammad Zubair Saleem et al.OncoTargets and therapy, 13, 435-450 (2020-02-06) RBCK1 promotes p53 degradation via ubiquitination in renal cell carcinoma.Sifan Yu et al.Cell death & disease, 10(4), 254-254 (2019-03-16) Benzo[b]fluoranthene Impairs Mouse Oocyte Maturation via Inducing the Apoptosis.Jing Guo et al.Frontiers in pharmacology, 11, 1226-1226 (2020-09-29) Elamipretide as a potential candidate for relieving cryodamage to human spermatozoa during cryopreservation.Hongwei Bai et al.Cryobiology, 95, 138-142 (2020-04-03) Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophagesLucy E Métayer et al.Oncotarget, 8(37), 60892-60903 (2017-10-06) Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.Gui-Hao Chen et al.Frontiers in pharmacology, 8, 775-775 (2017-11-23) Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system.Zhigang Jiao et al.Cell death discovery, 6, 78-78 (2020-09-05) Bardoxolone methyl (CDDO-Me or RTA402) induces cell cycle arrest, apoptosis and autophagy via PI3K/Akt/mTOR and p38 MAPK/Erk1/2 signaling pathways in K562 cells.Xin-Yu Wang et al.American journal of translational research, 9(10), 4652-4672 (2017-11-10) Doxorubicin and adjudin co-loaded pH-sensitive nanoparticles for the treatment of drug-resistant cancer.Qiong Wang et al.Acta biomaterialia, 94, 469-481 (2019-05-30) AMPK-activated protein kinase activation by Impatiens balsamina L. is related to apoptosis in HSC-2 human oral cancer cells.Ji-Ae Shin et al.Pharmacognosy magazine, 11(41), 136-142 (2015-02-25) Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT.Zongqi Wang et al.Cancer letters, 428, 21-33 (2018-04-28) miR-374a Inhibitor Enhances Etoposide-Induced Cytotoxicity Against Glioma Cells Through Upregulation of FOXO1.Wei Ni et al.Oncology research, 27(6), 703-712 (2019-03-08) Spatiotemporal control of mitochondrial network dynamics in astroglial cells.Jana Göbel et al.Biochemical and biophysical research communications, 500(1), 17-25 (2017-07-06) Structural basis and anticancer properties of ruthenium-based drug complexed with human serum albumin.Yao Zhang et al.European journal of medicinal chemistry, 86, 449-455 (2014-09-10) Downregulation of TIGAR sensitizes the antitumor effect of physapubenolide through increasing intracellular ROS levels to trigger apoptosis and autophagosome formation in human breast carcinoma cells.Ting Ma et al.Biochemical pharmacology, 143, 90-106 (2017-08-05) Artesunate exerts anti-prolactinoma activity by inhibiting mitochondrial metabolism and inducing apoptosis.Weiyu Zhang et al.Annals of translational medicine, 8(14), 858-858 (2020-08-15) SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction.Jennifer Gorwood et al.Cells, 9(4) (2020-04-05) Oil Sands Derived Naphthenic Acids Are Oxidative Uncouplers and Impair Electron Transport in Isolated Mitochondria.Kate I Rundle et al.Environmental science & technology, 52(18), 10803-10811 (2018-08-14) PEGylated Multistimuli-Responsive Dendritic Prodrug-Based Nanoscale System for Enhanced Anticancer Activity.Zhenyu Duan et al.ACS applied materials & interfaces, 10(42), 35770-35783 (2018-09-25) Novel half-sandwich iridium OˆC (carbene)-Complexes: In vitro and in vivo tumor growth suppression and pro-apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes.Zhishan Xu et al.Cancer letters, 447, 75-85 (2019-01-24) Kkot Byeol Kim et al.Nutrients, 10(10) (2018-09-27)Oxidative stress, which is induced by reactive oxygen species (ROS), causes cellular damage which contributes to the pathogenesis of neurodegenerative diseases. Momordica charantia (MC), a traditional medicinal plant, is known to have a variety of health benefits, such as antidiabetic... The Reduced Oligomerization of MAVS Mediated by ROS Enhances the Cellular Radioresistance.Yarong Du et al.Oxidative medicine and cellular longevity, 2020, 2167129-2167129 (2020-03-20) Mogroside V protects porcine oocytes from in vitro ageing by reducing oxidative stress through SIRT1 upregulation.Junyu Nie et al.Aging, 11(19), 8362-8373 (2019-10-07) A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway.Yasamin Dabiri et al.International journal of molecular sciences, 19(12) (2018-12-14) Blocking autophagy enhances the apoptotic effect of 18β-glycyrrhetinic acid on human sarcoma cells via endoplasmic reticulum stress and JNK activation.Shuying Shen et al.Cell death & disease, 8(9), e3055-e3055 (2017-09-22) Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.Ye Xu et al.Oncology reports, 34(6), 3051-3060 (2015-09-24) Acute effects of a prooxidant herbicide on the microalga Chlamydomonas reinhardtii: Screening cytotoxicity and genotoxicity endpoints.Marta Esperanza et al.Aquatic toxicology (Amsterdam, Netherlands), 165, 210-221 (2015-06-29) Activation of cannabinoid receptor 1 is involved in protection against mitochondrial dysfunction and cerebral ischaemic tolerance induced by isoflurane preconditioning.M Cai et al.British journal of anaesthesia, 119(6), 1213-1223 (2017-10-19) Aging impairs mitochondrial respiratory capacity in classical monocytes.Brandt D Pence et al.Experimental gerontology, 108, 112-117 (2018-04-16) Nanosecond Electric Pulses Induce Early and Late Phases of DNA Damage and Cell Death in Cisplatin-Resistant Human Ovarian Cancer Cells.Guanhua Qian et al.BioMed research international, 2018, 4504895-4504895 (2018-09-07) Electroacupuncture Pretreatment against Cerebral Ischemia/Reperfusion Injury through Mitophagy.Chenlu Mao et al.Evidence-based complementary and alternative medicine : eCAM, 2020, 7486041-7486041 (2020-09-24) Protective Effects of Memantine on Hydroquinone-Treated Human Retinal Pigment Epithelium Cells and Human Retinal Müller Cells.Mohamed Tarek Moustafa et al.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 33(8), 610-619 (2017-09-30) Luteolin induces intrinsic apoptosis via inhibition of E6/E7 oncogenes and activation of extrinsic and intrinsic signaling pathways in HPV-18-associated cells.Sunyoung Ham et al.Oncology reports, 31(6), 2683-2691 (2014-05-03) Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes.M Y Ansari et al.Osteoarthritis and cartilage, 26(8), 1087-1097 (2017-08-13) Deficient mitochondrial biogenesis in IL-2 activated NK cells correlates with impaired PGC1-α upregulation in elderly humans.Dante Miranda et al.Experimental gerontology, 110, 73-78 (2018-05-22) Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease.Xiaomin Xiong et al.Experimental cell research, 396(1), 112266-112266 (2020-09-10) MACC1 supports human gastric cancer growth under metabolic stress by enhancing the Warburg effect.L Lin et al.Oncogene, 34(21), 2700-2710 (2014-07-22) Proteomic mechanism of decabromodiphenyl ether (BDE-209) biodegradation by Microbacterium Y2 and its potential in remediation of BDE-209 contaminated water-sediment system.Yuanyuan Yu et al.Journal of hazardous materials, 387, 121708-121708 (2019-12-07) Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.Zongwei Gao et al.Oncotarget, 6(34), 36338-36353 (2015-10-16) Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.Hongtao Lu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4134-4146 (2020-01-14) Resistance assessment for SYP-14288 in Phytophthora capsici and changes in mitochondria electric potential-associated respiration and ATP production confers resistance.Zhiwen Wang et al.Pest management science, 76(7), 2525-2536 (2020-02-23) Sodium selenite (Na2SeO3) induces apoptosis through the mitochondrial pathway in CNE-2 nasopharyngeal carcinoma cells.Zhongyi Cui et al.International journal of oncology, 46(6), 2506-2514 (2015-04-22) Biodentine™ Boosts, WhiteProRoot®MTA Increases and Life® Suppresses Odontoblast Activity.Anabela Paula et al.Materials (Basel, Switzerland), 12(7) (2019-04-14) Interleukin-12p35 deficiency enhances mitochondrial dysfunction and aggravates cardiac remodeling in aging mice.Jing Ye et al.Aging, 12(1), 193-203 (2020-01-07) Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.Wen Su et al.Frontiers in pharmacology, 11, 202-202 (2020-03-27) The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.Eslam Mohamed et al.Immunity, 52(4), 668-682 (2020-04-16) Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Sun Woo Lim et al.Laboratory investigation; a journal of technical methods and pathology, 97(11), 1271-1281 (2017-08-02) PHD-2 activation: a novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype.Uma Devi et al.Naunyn-Schmiedeberg's archives of pharmacology, 392(10), 1239-1256 (2019-06-04) Nitrite attenuates mitochondrial impairment and vascular permeability induced by ischemia-reperfusion injury in the lung.Ajay Kumar et al.American journal of physiology. Lung cellular and molecular physiology, 318(4), L580-L591 (2020-02-20) Trans, trans-2,4-decadienal impairs vascular endothelial function by inducing oxidative/nitrative stress and apoptosis.Yuanyuan Hu et al.Redox biology, 34, 101577-101577 (2020-05-24) POH1 Knockdown Induces Cancer Cell Apoptosis via p53 and Bim.Chun-Hua Wang et al.Neoplasia (New York, N.Y.), 20(5), 411-424 (2018-03-25) Exploration of the optimal dose of HOE-642 for the protection of neuronal mitochondrial function after cardiac arrest in rats.Lanying Wei et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 110, 818-824 (2018-12-17) Sphingosine-1-Phosphate Reduces Hemorrhagic Shock and Resuscitation-Induced Microvascular Leakage by Protecting Endothelial Mitochondrial Integrity.Natascha G Alves et al.Shock (Augusta, Ga.), 52(4), 423-433 (2018-10-20) Apoptotic effects of ε-viniferin in combination with cis-platin in C6 cells.Filiz Özdemir et al.Cytotechnology, 70(3), 1061-1073 (2018-02-25) Citrus unshiu peel suppress the metastatic potential of murine melanoma B16F10 cells in vitro and in vivo.Eun Ok Choi et al.Phytotherapy research : PTR, 33(12), 3228-3241 (2019-09-06) Flexible ligated ruthenium(II) self-assemblies sensitizes glioma tumor initiating cellsPalani Elumalai et al.Oncotarget, 8(36), 60188-60200 (2017-09-28) Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.Ludger Hauck et al.PloS one, 12(12), e0189861-e0189861 (2017-12-22) Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.Bin Xu et al.Cells, 8(6) (2019-06-21) Glucuronorhamnoxylan from Capsosiphon fulvescens inhibits the growth of HT-29 human colon cancer cells in vitro and in vivo via induction of apoptotic cell death.Ji Won Choi et al.International journal of biological macromolecules, 124, 1060-1068 (2018-12-07) Silencing of PINK1 represses cell growth, migration and induces apoptosis of lung cancer cells.Lihua Liu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 106, 333-341 (2018-07-04) Resveratrol protects boar sperm in vitro via its antioxidant capacity.Linlin Sun et al.Zygote (Cambridge, England), 1-8 (2020-06-03) Induction of mitochondrial dysfunction and oxidative stress in Leishmania donovani by orally active clerodane diterpene.Manoj Kathuria et al.Antimicrobial agents and chemotherapy, 58(10), 5916-5928 (2014-07-30) Ectromelia Virus Affects Mitochondrial Network Morphology, Distribution, and Physiology in Murine Fibroblasts and Macrophage Cell Line.Karolina P Gregorczyk et al.Viruses, 10(5) (2018-05-19) Clostridium perfringens beta2 toxin induced in vitro oxidative damage and its toxic assessment in porcine small intestinal epithelial cell lines.Ruirui Luo et al.Gene, 759, 144999-144999 (2020-07-28) Nuclear Translocation of Calpain-2 Mediates Apoptosis of Hypertrophied Cardiomyocytes in Transverse Aortic Constriction Rat.Juan-Juan Sheng et al.Journal of cellular physiology, 230(11), 2743-2754 (2015-03-31) Akebia Saponin D inhibits the formation of atherosclerosis in ApoE-/- mice by attenuating oxidative stress-induced apoptosis in endothelial cells.Song Yang et al.Atherosclerosis, 285, 23-30 (2019-04-19) SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation.Yu Xiang et al.Life sciences, 256, 117971-117971 (2020-06-20) Ginsenoside Rk1 Induces Apoptosis in Neuroblastoma Cells Through Loss of Mitochondrial Membrane Potential and Activation of Caspases.Jung-Mi Oh et al.International journal of molecular sciences, 20(5) (2019-03-14) Boar seminal plasma inhibits cryo-capacitation of frozen-thawed ram sperm and improves fertility following intracervical insemination.Yi Fang et al.Theriogenology, 105, 84-89 (2017-09-25) Trehalose improves rabbit sperm quality during cryopreservation.Zhendong Zhu et al.Cryobiology, 75, 45-51 (2017-02-23) Oxycodone suppresses the apoptosis of hippocampal neurons induced by oxygen-glucose deprivation/recovery through caspase-dependent and caspase-independent pathways via κ- and δ-opioid receptors in rats.Cuicui Kong et al.Brain research, 1721, 146319-146319 (2019-07-06) Inhibition of Caspase-1-dependent pyroptosis attenuates copper-induced apoptosis in chicken hepatocytes.Jianzhao Liao et al.Ecotoxicology and environmental safety, 174, 110-119 (2019-03-02) Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment.Xing-Sheng Shu et al.Aging, 12(13), 13437-13462 (2020-06-24) Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus.H Fan et al.Cell death & disease, 5, e1416-e1416 (2014-09-12) HINT2 triggers mitochondrial CaLinghui Chen et al.Cancer letters, 411, 106-116 (2017-09-28) Asiatic acid supplementation during the in vitro culture period improves early embryonic development of porcine embryos produced by parthenogenetic activation, somatic cell nuclear transfer and in vitro fertilization.Jia-Jia Qi et al.Theriogenology, 142, 26-33 (2019-10-02) Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.Zheng-Zhi Zou et al.Oncotarget, 8(14), 22414-22432 (2015-10-16) Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans†.Rolando Pasquariello et al.Biology of reproduction, 100(4), 971-981 (2018-11-27) Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides.Zong-Rui Liu et al.Free radical research, 52(5), 616-628 (2018-05-22) Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway.Xianjun Tan et al.Journal of molecular neuroscience : MN, 70(11), 1728-1741 (2020-06-05) Salvianic acid A sodium protects HUVEC cells against tert-butyl hydroperoxide induced oxidative injury via mitochondria-dependent pathway.Dan Jia et al.Chemico-biological interactions, 279, 234-242 (2017-11-13) 3,4-Methylenedioxymethamphetamine causes cytotoxicity on 661W cells through inducing macrophage polarization.Xin Liu et al.Cutaneous and ocular toxicology, 37(2), 143-150 (2017-07-27) The effect of Ginsenoside Rg1 in hepatic ischemia reperfusion (I/R) injury ameliorates ischemia-reperfusion-induced liver injury by inhibiting apoptosis.Jie Lin et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 129, 110398-110398 (2020-07-01) Cytotoxicity of the methanol extracts of Elephantopus mollis, Kalanchoe crenata and 4 other Cameroonian medicinal plants towards human carcinoma cells.Victor Kuete et al.BMC complementary and alternative medicine, 17(1), 280-280 (2017-05-27) Enhanced apoptosis by pemetrexed and simvastatin in malignant mesothelioma and lung cancer cells by reactive oxygen species-dependent mitochondrial dysfunction and Bim induction.Ki-Eun Hwang et al.International journal of oncology, 45(4), 1769-1777 (2014-08-07) In vitro study evaluating the instantaneous treatment of ozonised olive oil on human sperm.Yan Fan et al.The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 23(2), 147-153 (2018-04-20) Role of adiponectin in the metabolism of skeletal muscles in collagen VI-related myopathies.Tania Gamberi et al.Journal of molecular medicine (Berlin, Germany), 97(6), 793-801 (2019-03-31) The ethyl acetate fraction of Sargassum muticum attenuates ultraviolet B radiation-induced apoptotic cell death via regulation of MAPK- and caspase-dependent signaling pathways in human HaCaT keratinocytes.Mei Jing Piao et al.Pharmaceutical biology, 52(9), 1110-1118 (2014-03-13) Development of Theragnostic Tool Using NIR Fluorescence Probe Targeting Mitochondria in Glioma Cells.Yeonjeong Chu et al.Bioconjugate chemistry, 30(6), 1642-1648 (2019-06-11) Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes.Vijaya L Damaraju et al.Biochemical pharmacology, 155, 162-171 (2018-07-10) Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo.Feng Wei et al.International journal of oncology, 51(5), 1383-1394 (2017-10-20) Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes.Qiong-Feng Wu et al.Cell death & disease, 8(5), e2828-e2828 (2017-05-26) The Effects of Phellinus linteus Polysaccharide Extracts on Cholesterol Efflux in Oxidized Low-Density Lipoprotein-Loaded THP-1 Macrophages.Xiao-hui Li et al.Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 63(5), 752-757 (2015-05-20) Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity.J R Vergara-Salinas et al.Food chemistry, 171, 62-69 (2014-10-14) Binding and Anticancer Properties of Plumbagin with Human Serum Albumin.Yi Gou et al.Chemical biology & drug design, 86(3), 362-369 (2014-12-24) Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH.Sangeeta Chakraborty et al.Nature communications, 11(1), 1783-1783 (2020-04-15) LncRNA UCA1 Promotes Mitochondrial Function of Bladder Cancer via the MiR-195/ARL2 Signaling Pathway.Hui-Jin Li et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(6), 2548-2561 (2017-11-14) Shape-dependent cellular toxicity on renal epithelial cells and stone risk of calcium oxalate dihydrate crystals.Xin-Yuan Sun et al.Scientific reports, 7(1), 7250-7250 (2017-08-05) N-acetyl cysteine protects human oral keratinocytes from Bis-GMA-induced apoptosis and cell cycle arrest by inhibiting reactive oxygen species-mediated mitochondrial dysfunction and the PI3K/Akt pathway.Yu Zhu et al.Toxicology in vitro : an international journal published in association with BIBRA, 29(8), 2089-2101 (2015-09-08) Sirt1 gene confers Adriamycin resistance in DLBCL via activating the PCG-1α mitochondrial metabolic pathway.Zhen Zhou et al.Aging, 12(12), 11364-11385 (2020-06-23) Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells.Jiyon Lee et al.BMC complementary and alternative medicine, 19(1), 134-134 (2019-06-20) (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one reduces lipoteichoic acid-induced damage in rat cardiomyoblast cells.Zhe Liu et al.Anatolian journal of cardiology, 19(3), 198-204 (2018-03-10) Effects of X-radiation on lung cancer cells: the interplay between oxidative stress and P53 levels.Fernando Mendes et al.Medical oncology (Northwood, London, England), 32(12), 266-266 (2015-11-20) Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells.Birol Özkal et al.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 36(6), 1283-1292 (2020-03-09) Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.Insun Park et al.Journal of computer-aided molecular design, 31(10), 929-941 (2017-09-16) Fatty acid ethyl esters disrupt neonatal alveolar macrophage mitochondria and derange cellular functioning.Sowmya S Mohan et al.Alcoholism, clinical and experimental research, 39(3), 434-444 (2015-02-24) Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy.Jianpeng Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 114, 108844-108844 (2019-04-14) Momordica charantia lectin exhibits antitumor activity towards hepatocellular carcinoma.Chris Zhiyi Zhang et al.Investigational new drugs, 33(1), 1-11 (2014-09-10) Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.Yen-Yun Wang et al.Head & neck, 39(6), 1055-1064 (2017-03-28) The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells.Haiyan Sun et al.Biochemical pharmacology, 146, 87-100 (2017-10-28) Using redox-sensitive mitochondrial cytochrome Raman bands for label-free detection of mitochondrial dysfunction.Takeshi Morimoto et al.The Analyst, 144(8), 2531-2540 (2019-03-07) Bioenergetic Impairment in Congenital Muscular Dystrophy Type 1A and Leigh Syndrome Muscle Cells.Cibely C Fontes-Oliveira et al.Scientific reports, 7, 45272-45272 (2017-04-04) Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages.Muhammed Enes Inanc et al.Animal reproduction science, 193, 191-200 (2018-04-28) Alleviation of Ischemia-Reperfusion Injury in Liver Steatosis by Augmenter of Liver Regeneration Is Attributed to Antioxidation and Preservation of Mitochondria.Junhua Weng et al.Transplantation, 101(10), 2340-2348 (2017-07-14) Carnosic Acid Pretreatment Attenuates Mitochondrial Dysfunction in SH-SY5Y Cells in an Experimental Model of Glutamate-Induced Excitotoxicity.Marcos Roberto de Oliveira et al.Neurotoxicity research, 36(3), 551-562 (2019-04-25) Cellular responses to T-2 toxin and/or deoxynivalenol that induce cartilage damage are not specific to chondrocytes.Yang Lei et al.Scientific reports, 7(1), 2231-2231 (2017-05-24) Polydatin prevents the induction of secondary brain injury after traumatic brain injury by protecting neuronal mitochondria.Li Li et al.Neural regeneration research, 14(9), 1573-1582 (2019-05-16) Rosuvastatin Improves Neurite Outgrowth of Cortical Neurons against Oxygen-Glucose Deprivation via Notch1-mediated Mitochondrial Biogenesis and Functional Improvement.Weiliang He et al.Frontiers in cellular neuroscience, 12, 6-6 (2018-02-02) Synergistic effects of 5-fluorouracil and gambogenic acid on A549 cells: activation of cell death caused by apoptotic and necroptotic mechanisms via the ROS-mitochondria pathway.Jingjing Su et al.Biological & pharmaceutical bulletin, 37(8), 1259-1268 (2014-08-05) ROS changes are responsible for tributyl phosphate (TBP)-induced toxicity in the alga Phaeodactylum tricornutum.Qian Liu et al.Aquatic toxicology (Amsterdam, Netherlands), 208, 168-178 (2019-01-25) T1-11, an adenosine derivative, ameliorates aging-related behavioral physiology and senescence markers in aging mice.Wei-Hsiang Hsu et al.Aging, 12(11), 10556-10577 (2020-06-06) Zinc protects chondrocytes from monosodium iodoacetate-induced damage by enhancing ATP and mitophagy.Li-Wen Huang et al.Biochemical and biophysical research communications, 521(1), 50-56 (2019-10-16) N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.Hongqing Xie et al.International journal of molecular sciences, 21(16) (2020-08-23) Pennogenyl saponins induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.Fang-Yi Long et al.Journal of ethnopharmacology, 162, 112-120 (2015-01-07) Non-classical platinum-based compound 56MESS, with preferential cytotoxic effect on oral cancer cells by downregulating FACL4 expression.Lejing Miao et al.Die Pharmazie, 75(10), 494-499 (2020-12-12) Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A.Karine Z Oben et al.Oncotarget, 8(44), 77436-77452 (2017-11-05) Inhibition of soluble epoxide hydrolase attenuates renal tubular mitochondrial dysfunction and ER stress by restoring autophagic flux in diabetic nephropathy.Xu-Shun Jiang et al.Cell death & disease, 11(5), 385-385 (2020-05-23) Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer.Eun-Sun Choi et al.Scientific reports, 4, 7162-7162 (2014-11-25) Baicalin induces apoptosis of gallbladder carcinoma cells in vitro via a mitochondrial-mediated pathway and suppresses tumor growth in vivo.Yi-Jun Shu et al.Anti-cancer agents in medicinal chemistry, 14(8), 1136-1145 (2014-02-27) Effects and Mechanisms of Vitamin C Post-Conditioning on Platelet Activation after Hypoxia/Reoxygenation.Demin Liu et al.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 47(2), 110-118 (2020-05-02) Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells.Petro P Czupiel et al.Journal of controlled release : official journal of the Controlled Release Society, 305, 210-219 (2019-05-10) Change of the metabolomic profile during short-term mononuclear cell storage.P A Steininger et al.Vox sanguinis, 112(2), 163-172 (2017-01-05) Activation of Farnesoid X Receptor by Schaftoside Ameliorates Acetaminophen-Induced Hepatotoxicity by Modulating Oxidative Stress and Inflammation.Meijing Liu et al.Antioxidants & redox signaling, 33(2), 87-116 (2020-02-11) Adenine Nucleotide Translocase 1 Expression is Coupled to the HSP27-Mediated TLR4 Signaling in Cardiomyocytes.Julia Winter et al.Cells, 8(12) (2019-12-11) Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages.Janos Priber et al.Biochemistry and cell biology = Biochimie et biologie cellulaire, 93(3), 241-250 (2015-03-03) Berberine-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway.Juan Xie et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(2), 1279-1288 (2014-10-30) Protective Effect of Fenofibrate on Oxidative Stress-Induced Apoptosis in Retinal-Choroidal Vascular Endothelial Cells: Implication for Diabetic Retinopathy Treatment.Ying-Jung Hsu et al.Antioxidants (Basel, Switzerland), 9(8) (2020-08-09) Melatonin-induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence.Bin He et al.Journal of cellular physiology, 233(1), 302-312 (2017-02-28) Biofunctionalization of selenium nanoparticles with a polysaccharide from Rosa roxburghii fruit and their protective effect against H2O2-induced apoptosis in INS-1 cells.Lei Wang et al.Food & function, 10(2), 539-553 (2019-01-22) Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.Ahmed Elkamhawy et al.European journal of medicinal chemistry, 128, 56-69 (2017-02-06) Piceatannol-Induced Apoptosis Is Reversed by N-Acetyl-L-cysteine through Restoration of XIAP Expression.Cheng-Yun Jin et al.Biological & pharmaceutical bulletin, 41(9), 1372-1378 (2018-09-04) Norcantharidin induces mitochondrial-dependent apoptosis through Mcl-1 inhibition in human prostate cancer cells.Chu-Liang Lin et al.Biochimica et biophysica acta, 1864(10), 1867-1876 (2017-08-02) Bis-guanylhydrazones as efficient anti-Candida compounds through DNA interaction.Jelena Lazić et al.Applied microbiology and biotechnology, 102(4), 1889-1901 (2018-01-14) Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.Xiaokui Huo et al.British journal of pharmacology, 177(9), 1933-1948 (2020-01-31) Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING.Lauren D Aarreberg et al.Molecular cell, 74(4), 801-815 (2019-04-07) 2-O-β-d-glucopyranosyl-l-ascorbic acid, a novel vitamin C derivative from Lycium barbarum, prevents oxidative stress.Shen-Fei Wang et al.Redox biology, 24, 101173-101173 (2019-03-25) Experimental study of a novel tumstatin on C6 brain gliomaPengguo Zhang et al.Oncology letters, 14(3), 2845-2851 (2017-09-21) SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.Xiangyuan Chen et al.Acta biochimica et biophysica Sinica, 50(7), 635-642 (2018-05-16) Tumor acidity activated triphenylphosphonium-based mitochondrial targeting nanocarriers for overcoming drug resistance of cancer therapy.Hui Yu et al.Theranostics, 9(23), 7033-7050 (2019-10-30) Strategic design of cardiac mimetic core-shell nanofibrous scaffold impregnated with Salvianolic acid B and Magnesium l-ascorbic acid 2 phosphate for myoblast differentiation.Ekambaram Shoba et al.Materials science & engineering. C, Materials for biological applications, 90, 131-147 (2018-06-02) Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression.Sandhya V G Nair et al.PloS one, 9(9), e107149-e107149 (2014-09-18) Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis.Pyone Myat Thu et al.European journal of pharmacology, 850, 23-34 (2019-02-05) Complete destruction of deep-tissue buried tumors via combination of gene silencing and gold nanoechinus-mediated photodynamic therapy.Priya Vijayaraghavan et al.Biomaterials, 62, 13-23 (2015-05-29) Madecassic acid inhibits the mouse colon cancer growth by inducing apoptosis and immunomodulation.Hua Zhang et al.Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 19(2), 372-376 (2014-06-27) miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets.Shifang Yu et al.PloS one, 10(4), e0122784-e0122784 (2015-04-16) Thymol exposure mediates pro-oxidant shift by regulating Nrf2 and apoptotic events in zebrafish (Danio rerio) embryos.Manigandan Krishnan et al.Environmental toxicology and pharmacology, 65, 1-8 (2018-11-23) SILAC-based proteomic analysis reveals that salidroside antagonizes cobalt chloride-induced hypoxic effects by restoring the tricarboxylic acid cycle in cardiomyocytes.Zhong-Wei Xu et al.Journal of proteomics, 130, 211-220 (2015-10-06) Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles.Shuo Liu et al.Molecular pharmaceutics, 17(4), 1415-1427 (2020-03-12) Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation.Qi Yuan et al.Cell death & disease, 11(5), 355-355 (2020-05-13) 6H2L, a novel synthetic derivative of bifendate, induces apoptosis in hepatoma cells via mitochondrial and MAPK pathway.Lirong Yu et al.European journal of pharmacology, 882, 173299-173299 (2020-06-27) PINK1/Parkin mediated mitophagy ameliorates palmitic acid-induced apoptosis through reducing mitochondrial ROS production in podocytes.Xu-Shun Jiang et al.Biochemical and biophysical research communications, 525(4), 954-961 (2020-03-17) Nanoparticle delivery of a pH-sensitive prodrug of doxorubicin and a mitochondrial targeting VES-H8R8 synergistically kill multi-drug resistant breast cancer cells.Petro Czupiel et al.Scientific reports, 10(1), 8726-8726 (2020-05-28) Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.Yuliang Xu et al.Ecotoxicology and environmental safety, 194, 110414-110414 (2020-03-11) Simvastatin protects photoreceptors from oxidative stress induced by all-trans-retinal, through the up-regulation of interphotoreceptor retinoid binding protein.Ting Zhang et al.British journal of pharmacology, 176(12), 2063-2078 (2019-03-03) Midazolam and Dexmedetomidine Affect Neuroglioma and Lung Carcinoma Cell Biology In Vitro and In Vivo.Chunyan Wang et al.Anesthesiology, 129(5), 1000-1014 (2018-08-30) Cytotoxic Acetogenins from the Roots of Annona purpurea.Gustavo Alejandro Hernández-Fuentes et al.International journal of molecular sciences, 20(8) (2019-04-25) Yap regulates mitochondrial structural remodeling during myoblast differentiation.Shiyuan Huang et al.American journal of physiology. Cell physiology, 315(4), C474-C484 (2018-06-14) Mitochondrial dysfunction is responsible for fatty acid synthase inhibition-induced apoptosis in breast cancer cells by PdpaMn.Qiang Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 96, 396-403 (2017-10-17) 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.Ching-Chyuan Su et al.Marine drugs, 12(10), 5295-5315 (2014-10-25) Non-toxic fluorescent phosphonium probes to detect mitochondrial potential.Ana Šarić et al.Methods and applications in fluorescence, 5(1), 015007-015007 (2017-03-23) Cratoxy formosum leaf extract inhibits proliferation and migration of human breast cancer MCF-7 cells.Benjaporn Buranrat et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 90, 77-84 (2017-03-28) Melatonin-mediated β-catenin activation protects neuron cells against prion protein-induced neurotoxicity.Jae-Kyo Jeong et al.Journal of pineal research, 57(4), 427-434 (2014-09-25) Autophagic flux induced by graphene oxide has a neuroprotective effect against human prion protein fragments.Jae-Kyo Jeong et al.International journal of nanomedicine, 12, 8143-8158 (2017-12-01) Characteristics of enterovirus 71-induced cell death and genome scanning to identify viral genes involved in virus-induced cell apoptosis.Jinjin Bai et al.Virus research, 265, 104-114 (2019-03-27) Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS.Shanling Yi et al.American journal of physiology. Endocrinology and metabolism, 319(1), E91-E101 (2020-04-29) Identification of new shikonin derivatives as STAT3 inhibitors.Han-Yue Qiu et al.Biochemical pharmacology, 146, 74-86 (2017-10-27) Chrysosplenol d, a Flavonol from Artemisia annua, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells.Sophia J Lang et al.International journal of molecular sciences, 21(11) (2020-06-12) Anti-tumor effect of LATS2 on liver cancer death: Role of DRP1-mediated mitochondrial division and the Wnt/β-catenin pathway.Lijuan Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 114, 108825-108825 (2019-04-14) Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy.Hao Zhou et al.Cell death and differentiation, 25(6), 1080-1093 (2018-03-16) Cold Atmospheric Plasma induces accumulation of lysosomes and caspase-independent cell death in U373MG glioblastoma multiforme cells.Gillian E Conway et al.Scientific reports, 9(1), 12891-12891 (2019-09-11) Neuroprotective effects of ZL006 in Aβ1-42-treated neuronal cells.Wen-Yuan Tao et al.Neural regeneration research, 15(12), 2296-2305 (2020-07-01) MiR-126 reverses drug resistance to TRAIL through inhibiting the expression of c-FLIP in cervical cancer.Weijiang Zhang et al.Gene, 627, 420-427 (2017-07-04) Oxygen concentration alters mitochondrial structure and function in in vitro fertilized preimplantation mouse embryos.Manuel Belli et al.Human reproduction (Oxford, England), 34(4), 601-611 (2019-03-14) Acetaminophen toxicity in rat and mouse hepatocytes in vitro.Otto Kučera et al.Drug and chemical toxicology, 40(4), 448-456 (2016-12-15) Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer.Hisamitsu Ide et al.Cancer science, 109(4), 1230-1238 (2018-01-26) Chitosan oligosaccharides prevent doxorubicin-induced oxidative stress and cardiac apoptosis through activating p38 and JNK MAPK mediated Nrf2/ARE pathway.Yongtian Zhang et al.Chemico-biological interactions, 305, 54-65 (2019-04-01) Hapalindole H Induces Apoptosis as an Inhibitor of NF-ĸB and Affects the Intrinsic Mitochondrial Pathway in PC-3 Androgen-insensitive Prostate Cancer Cells.Ulyana Muñoz Acuña et al.Anticancer research, 38(6), 3299-3307 (2018-06-01) Ulinastatin inhibits high glucose-induced cardiomyocyte apoptosis through activating Akt signaling.Y Long et al.European review for medical and pharmacological sciences, 22(14), 4691-4697 (2018-07-31) Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells.Feifan Wang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4266-4282 (2020-01-21) Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells).Hindupur Ravi et al.Materials science & engineering. C, Materials for biological applications, 91, 785-795 (2018-07-24) Inhibitory effects of JQ1 on listeria monocytogenes-induced acute liver injury by blocking BRD4/RIPK1 axis.Zhao Qian et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 109818-109818 (2020-02-29) Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of coptisine against oxidative stress-induced DNA damage and apoptosis in HaCaT keratinocytes.Yung Hyun Choi General physiology and biophysics, 38(4), 281-294 (2019-06-21) Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite.Srabanti Rakshit et al.Biochimica et biophysica acta, 1843(11), 2645-2661 (2014-07-02) Comparison of cardioprotective effects of labeled and unlabeled oleanoic acids with new BOPIM dye on primary neonatal rat cardiomyocytes following hypoxia/reoxygenation injury.Sa Wang et al.Pharmacological reports : PR, 66(4), 677-685 (2014-06-21) Glutamine Reduces the Apoptosis of H9C2 Cells Treated with High-Glucose and Reperfusion through an Oxidation-Related Mechanism.Kai Li et al.PloS one, 10(7), e0132402-e0132402 (2015-07-07) FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.Chengyu Li et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 3631-3645 (2020-01-22) Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells.Xiao-Huang Xu et al.Planta medica, 83(3-04), 254-260 (2016-07-28) In vitro cytotoxic and toxicological activities of ethanolic extract of Kaempferia galanga Linn. and its active component, ethyl-p-methoxycinnamate, against cholangiocarcinoma.Porwornwisit Tritripmongkol et al.Journal of integrative medicine, 18(4), 326-333 (2020-05-19) New life for an old drug: In vitro and in vivo effects of the anthelmintic drug niclosamide against Toxoplasma gondii RH strain.Ji Li Zhang et al.International journal for parasitology. Drugs and drug resistance, 9, 27-34 (2019-01-02) Dexmedetomidine Alleviates Hyperoxia-Induced Acute Lung Injury via Inhibiting NLRP3 Inflammasome Activation.Qiuyue Zhang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(5), 1907-1919 (2017-09-06) Silibinin prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease via mitochondrial stabilization.Yujeong Lee et al.Journal of neuroscience research, 93(5), 755-765 (2015-02-14) High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells.Sweta Pal et al.Life sciences, 256, 117914-117914 (2020-06-09) Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/β-catenin/c-Myc signaling pathway in human gastric cancer cell.Yudong Hu et al.Biochemical pharmacology, 150, 280-292 (2018-02-24) Inhibition effects of perfluoroalkyl acids on progesterone production in mLTC-1.Wei Zhao et al.Journal of environmental sciences (China), 56, 272-280 (2017-06-03) Protective effect of isoliquiritin against corticosterone-induced neurotoxicity in PC12 cells.Yu-Zhi Zhou et al.Food & function, 8(3), 1235-1244 (2017-02-24) Melatonin Improves the Fertilization Capacity of Sex-Sorted Bull Sperm by Inhibiting Apoptosis and Increasing Fertilization Capacitation via MT1.Chong-Yang Li et al.International journal of molecular sciences, 20(16) (2019-08-15) Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.Yanqiu Wang et al.Aging, 11(18), 7961-7977 (2019-09-24) A pH-Sensitive Prodrug Nanocarrier Based on Diosgenin for Doxorubicin Delivery to Efficiently Inhibit Tumor Metastasis.Zeliang Wei et al.International journal of nanomedicine, 15, 6545-6560 (2020-09-19) Arctium lappa L. root extract induces cell death via mitochondrial-mediated caspase-dependent apoptosis in Jurkat human leukemic T cells.Ravini Ayoddhia Sirilal Gurunanselage Don et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 110, 918-929 (2018-12-21) Autocrine secretion of 15d-PGJ2 mediates simvastatin-induced apoptotic burst in human metastatic melanoma cells.Christine Wasinger et al.British journal of pharmacology, 171(24), 5708-5727 (2014-08-06) LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway.Zeyuan Yin et al.Experimental and therapeutic medicine, 13(6), 2819-2827 (2017-06-08) Apatinib exhibits cytotoxicity toward leukemia cells by targeting VEGFR2-mediated prosurvival signaling and angiogenesis.Manman Deng et al.Experimental cell research, 390(1), 111934-111934 (2020-03-04) Catalpol Inhibits Ischemia-Induced Premyelinating Oligodendrocyte Damage through Regulation of Intercellular Calcium Homeostasis via Na⁺/Ca2+ Exchanger 3.Qiyan Cai et al.International journal of molecular sciences, 19(7) (2018-07-04) Inhibition of didscoidin domain receptor 1 reduces epithelial-mesenchymal transition and induce cell-cycle arrest and apoptosis in prostate cancer cell lines.Reza Azizi et al.Journal of cellular physiology, 234(11), 19539-19552 (2019-04-10) Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction.Xiao-Xin Chen et al.Journal of agricultural and food chemistry, 66(27), 7054-7064 (2018-06-20) Apoptotic death of prostate cancer cells by a gonadotropin-releasing hormone-II antagonist.Sumi Park et al.PloS one, 9(6), e99723-e99723 (2014-06-14) Accumulation of electrophilic aldehydes during postovulatory aging of mouse oocytes causes reduced fertility, oxidative stress, and apoptosis.Tessa Lord et al.Biology of reproduction, 92(2), 33-33 (2014-12-17) Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo.Chenxuan Wu et al.Nutrients, 11(5) (2019-05-01) A new molecular mechanism underlying the EGCG-mediated autophagic modulation of AFP in HepG2 cells.Lin Zhao et al.Cell death & disease, 8(11), e3160-e3160 (2017-11-03) Protective effect and mechanism of lycopene on endothelial progenitor cells (EPCs) from type 2 diabetes mellitus rats.Yao-Chi Zeng et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 92, 86-94 (2017-05-23) RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma.Qianqian Yu et al.OncoTargets and therapy, 11, 7591-7600 (2018-11-23) Prostate cancer Lncap stem-like cells demonstrate resistance to the hydros-induced apoptosis during the formation of spheres.Yan Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 74, 1-8 (2015-09-10) Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.Rui Huang et al.PloS one, 9(5), e96246-e96246 (2014-05-13) Rosmarinic Acid Mitigates Mitochondrial Dysfunction and Spinal Glial Activation in Oxaliplatin-induced Peripheral Neuropathy.Aparna Areti et al.Molecular neurobiology, 55(9), 7463-7475 (2018-02-11) Brazilian green propolis induced apoptosis in human lung cancer A549 cells through mitochondrial-mediated pathway.Yahima Frión-Herrera et al.The Journal of pharmacy and pharmacology, 67(10), 1448-1456 (2015-07-25) Klotho Alleviates Lung Injury Caused by Paraquat via Suppressing ROS/P38 MAPK-Regulated Inflammatory Responses and Apoptosis.Zhiqiang Zhang et al.Oxidative medicine and cellular longevity, 2020, 1854206-1854206 (2020-06-09) Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis.Mei-Jen Wang et al.Cells, 9(1) (2019-12-22) Resveratrol attenuates cerebral ischaemia reperfusion injury via modulating mitochondrial dynamics homeostasis and activating AMPK-Mfn1 pathway.Jinbao Gao et al.International journal of experimental pathology, 100(5-6), 337-349 (2019-12-24) The apoptotic effect of apigenin on human gastric carcinoma cells through mitochondrial signal pathway.Jiayu Chen et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(8), 7719-7726 (2014-05-09) Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells.Xuenong Zhang et al.Journal of breast cancer, 18(2), 112-118 (2015-07-15) Potential crosstalk of Ca2+-ROS-dependent mechanism involved in apoptosis of Kasumi-1 cells mediated by heme oxygenase-1 small interfering RNA.Sixi Wei et al.International journal of oncology, 45(6), 2373-2384 (2014-09-19) Lychee (Litchi chinensis Sonn.) Pulp Phenolic Extract Confers a Protective Activity against Alcoholic Liver Disease in Mice by Alleviating Mitochondrial Dysfunction.Juan Xiao et al.Journal of agricultural and food chemistry, 65(24), 5000-5009 (2017-06-01) Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis.Yang Guo et al.Journal of cellular and molecular medicine, 19(2), 340-350 (2014-10-22) Inhibition of mitochondrial translation selectively targets osteosarcoma.Jianguo Chen et al.Biochemical and biophysical research communications, 515(1), 9-15 (2019-05-24) CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii.Chunhuan Jin et al.Molecules (Basel, Switzerland), 24(11) (2019-06-12) Sox2 is involved in paclitaxel resistance of the prostate cancer cell line PC-3 via the PI3K/Akt pathway.Dong Li et al.Molecular medicine reports, 10(6), 3169-3176 (2014-10-14) Synthesis, characterization and antitumor properties of selenium nanoparticles coupling with ferulic acid.Dongxiao Cui et al.Materials science & engineering. C, Materials for biological applications, 90, 104-112 (2018-06-02) Stigmasterol Causes Ovarian Cancer Cell Apoptosis by Inducing Endoplasmic Reticulum and Mitochondrial Dysfunction.Hyocheol Bae et al.Pharmaceutics, 12(6) (2020-06-03) Circular RNA CCDC66 facilitates abdominal aortic aneurysm through the overexpression of CCDC66.Rui Yang et al.Cell biochemistry and function, 38(7), 830-838 (2020-01-31) A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor.Yin Li et al.Current cancer drug targets, 15(6), 493-503 (2015-08-19) Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells.Maria Kawalec et al.PloS one, 10(7), e0134162-e0134162 (2015-08-01) Protection of human retinal pigment epithelial cells from oxidative damage using cysteine prodrugs.Ruvanthi N Kularatne et al.Free radical biology & medicine, 152, 386-394 (2020-04-02) Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis.Ning-Ping Zhang et al.Laboratory investigation; a journal of technical methods and pathology, 99(6), 749-763 (2019-02-01) Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway.Jaeyoon Kim et al.Molecules (Basel, Switzerland), 25(17) (2020-09-06) 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Alleviates Atherosclerosis via Enhancing Efferocytosis and Facilitating a Shift in the Th1/Th2 Balance Toward Th2 Polarization.Yang Yang et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(1), 83-96 (2018-05-16) CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling.Lixia Gao et al.Journal of experimental & clinical cancer research : CR, 39(1), 73-73 (2020-04-30) Notch1 inhibition enhances DNA damage induced by cisplatin in cervical cancer.ShiRong Li et al.Experimental cell research, 376(1), 27-38 (2019-01-29) An analog derived from phenylpropanoids ameliorates Alzheimer's disease-like pathology and protects mitochondrial function.Shichao Huang et al.Neurobiology of aging, 80, 187-195 (2019-06-17) Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes.Pamela Bachour-El Azzi et al.Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 157-168 (2015-02-19) Alterations in the mitochondrial responses to PENAO as a mechanism of resistance in ovarian cancer cells.Stéphanie Decollogne et al.Gynecologic oncology, 138(2), 363-371 (2015-06-17) Mitochonic acid-5 attenuates TNF-α-mediated neuronal inflammation via activating Parkin-related mitophagy and augmenting the AMPK-Sirt3 pathways.Dezhi Huang et al.Journal of cellular physiology, 234(12), 22172-22182 (2019-05-08) Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.Xiju He et al.Proceedings of the National Academy of Sciences of the United States of America, 114(23), E4582-E4591 (2017-05-21) Madhulika Bhagat et al.Current topics in medicinal chemistry, 20(22), 1981-1992 (2020-07-25)The aim of this study is to explore essential oil from the bark of Cedrus deodara (CDEO) as an potential anticancer agent. The frontline drugs against cancer in clinical settings are posing challenges of resistance and other detrimental side-effects. This... Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic coupling.Kexin Sun et al.EBioMedicine, 41, 370-383 (2019-02-26) Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo.Claudia Schmidt et al.Oncotarget, 8(33), 55147-55161 (2017-09-15) Mitochondrial alkaline pH-responsive drug release mediated by Celastrol loaded glycolipid-like micelles for cancer therapy.Yanan Tan et al.Biomaterials, 154, 169-181 (2017-11-13) Neuroprotective effect of trans-N-caffeoyltyramine from Lycium chinense against HOpeyemi J Olatunji et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 93, 895-902 (2017-07-19) Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium.Z M Jiang et al.Die Pharmazie, 73(2), 87-91 (2018-02-15) Capability of iturin from Bacillus subtilis to inhibit Candida albicans in vitro and in vivo.Shuzhen Lei et al.Applied microbiology and biotechnology, 103(11), 4377-4392 (2019-04-19) Hydrogen peroxide induces programmed necrosis in rat nucleus pulposus cells through the RIP1/RIP3-PARP-AIF pathway.Lei Zhao et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 36(4), 1269-1282 (2017-09-30) Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway.Ji-Hyun Park et al.Journal of neuroinflammation, 14(1), 240-240 (2017-12-13) Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.Jing Zhang et al.Journal of ethnopharmacology, 221, 91-99 (2018-04-17) A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells.Didem Karakaş et al.Turkish journal of biology = Turk biyoloji dergisi, 43(4), 256-263 (2019-10-05) Evaluation of drug combination for glioblastoma based on an intestine-liver metabolic model on microchip.Mingsha Jie et al.The Analyst, 142(19), 3629-3638 (2017-08-31) Thermodynamic interference with bile acid demicelleization reduces systemic entry and injury during cholestasis.Cristiane de Oliveira et al.Scientific reports, 10(1), 8462-8462 (2020-05-23) Reactive oxygen species induced by icaritin promote DNA strand breaks and apoptosis in human cervical cancer cells.Xin Chen et al.Oncology reports, 41(2), 765-778 (2018-11-16) miR‑21/PTEN pathway mediates the cardioprotection of geniposide against oxidized low‑density lipoprotein‑induced endothelial injury via suppressing oxidative stress and inflammatory response.Song Zhou et al.International journal of molecular medicine, 45(5), 1305-1316 (2020-04-24) Intracellular antioxidant activity and apoptosis inhibition capacity of PEF-treated KDHCH in HepG2 cells.Rong Liang et al.Food research international (Ottawa, Ont.), 121, 336-347 (2019-05-22) Asiaticoside Attenuates Cell Growth Inhibition and Apoptosis Induced by AβDaqiang Song et al.Frontiers in pharmacology, 9, 28-28 (2018-02-15) Preparation and Characterization of Dictyophora indusiata Polysaccharide-Zinc Complex and Its Augmented Antiproliferative Activity on Human Cancer Cells.Wenzhen Liao et al.Journal of agricultural and food chemistry, 63(29), 6525-6534 (2015-07-15) α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway.Xiao-Dong Pei et al.European journal of pharmacology, 883, 173355-173355 (2020-07-21) Protective effects of 3β-angeloyloxy-8β, 10β-dihydroxyeremophila-7(11)-en-12, 8α-lactone on paraquat-induced oxidative injury in SH-SY5Y cells.Qi-Lin Wang et al.Journal of Asian natural products research, 21(4), 364-376 (2018-01-23) High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis.Taro Narumi et al.Journal of molecular and cellular cardiology, 82, 1-12 (2015-03-05) Suppression of miR-1197-3p attenuates H2O2-induced apoptosis of goat luteinized granulosa cells via targeting PPARGC1A.Guo-Min Zhang et al.Theriogenology, 132, 72-82 (2019-04-20) Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.Leilei Zhang et al.Scientific reports, 7(1), 1669-1669 (2017-05-12) Wenxin Granule Ameliorates Hypoxia/Reoxygenation-Induced Oxidative Stress in Mitochondria via the PKC-δ/NOX2/ROS Pathway in H9c2 Cells.Qihui Jin et al.Oxidative medicine and cellular longevity, 2020, 3245483-3245483 (2020-06-23) Role of mitochondria in the leishmanicidal effects and toxicity of acyl phloroglucinol derivatives: nemorosone and guttiferone A.Lianet Monzote et al.Parasitology, 142(9), 1239-1248 (2015-06-02) Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells.Ismail Ismailoglu et al.Developmental biology, 391(2), 230-240 (2014-05-02) Downregulation of TRAP1 aggravates injury of H9c2 cardiomyocytes in a hyperglycemic state.Xiaodan Zhang et al.Experimental and therapeutic medicine, 18(4), 2681-2686 (2019-10-02) Sodium Butyrate-Modulated Mitochondrial Function in High-Insulin Induced HepG2 Cell Dysfunction.Tingting Zhao et al.Oxidative medicine and cellular longevity, 2020, 1904609-1904609 (2020-07-30) Epigallocatechin gallate promotes the development of mouse 2-cell embryos in vitro by regulating mitochondrial activity and expression of genes related to p53 signalling pathway.Weiyu Zhang et al.Basic & clinical pharmacology & toxicology, 115(5), 403-410 (2014-04-23) Ring-Substituted 1-Hydroxynaphthalene-2-Carboxanilides Inhibit Proliferation and Trigger Mitochondria-Mediated Apoptosis.Tereza Kauerová et al.International journal of molecular sciences, 21(10) (2020-05-16) Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.Bernadette McEvoy et al.The Journal of physiology, 593(23), 5167-5182 (2015-10-21) Inhibition of mTOR's Catalytic Site by PKI-587 Is a Promising Therapeutic Option for Gastroenteropancreatic Neuroendocrine Tumor Disease.Helma Freitag et al.Neuroendocrinology, 105(1), 90-104 (2016-08-12) 4-hydroxynonenal regulates mitochondrial function in human small airway epithelial cells.Lakshmi Galam et al.Oncotarget, 6(39), 41508-41521 (2015-10-21) 3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells.Yaomin Wang et al.International journal of oncology, 50(4), 1392-1402 (2017-03-06) A Novel Polyhalogenated Monoterpene Induces Cell Cycle Arrest and Apoptosis in Breast Cancer Cells.Menna El Gaafary et al.Marine drugs, 17(8) (2019-07-28) Low-level light in combination with metabolic modulators for effective therapy of injured brain.Tingting Dong et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(9), 1435-1444 (2015-05-15) Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo.Georg Karpel-Massler et al.Oncotarget, 6(16), 14507-14521 (2015-05-27) D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH.K Oizel et al.Cell death & disease, 6, e1704-e1704 (2015-03-27) Effects of Nicotinamide on Cervical Cancer-Derived Fibroblasts: Evidence for Therapeutic Potential.Reem N Hassan et al.Cancer management and research, 12, 1089-1100 (2020-02-28) Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling.Anja Heinemann et al.Oncotarget, 6(25), 21507-21521 (2015-06-19) Experimental Study of Shenfu Injection on the Prevention and Treatment of Paclitaxel Chemotherapy DRG Neuron Injury.Panpan Lv et al.Evidence-based complementary and alternative medicine : eCAM, 2020, 8239650-8239650 (2020-04-08) Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: the involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway.Guk Heui Jo et al.International journal of oncology, 45(4), 1497-1506 (2014-07-06) PM2.5 triggered apoptosis in lung epithelial cells through the mitochondrial apoptotic way mediated by a ROS-DRP1-mitochondrial fission axis.Xiaoying Liu et al.Journal of hazardous materials, 397, 122608-122608 (2020-05-11) Duloxetine Reduces Oxidative Stress, Apoptosis, and CaArif Demirdaş et al.Molecular neurobiology, 54(6), 4683-4695 (2016-07-23) PGC-1α-Mediated Mitochondrial Biogenesis is Involved in Cannabinoid Receptor 2 Agonist AM1241-Induced Microglial Phenotype Amelioration.Lei Ma et al.Cellular and molecular neurobiology, 38(8), 1529-1537 (2018-10-14) Malic enzyme 1 is important for uterine decidualization in response to progesterone/cAMP/PKA/HB-EGF pathway.Hai-Fan Yu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 3820-3837 (2020-01-17) Fractionation and Characterization of Lycopene-Oxidation Products by LC-MS/MS (ESI)+: Elucidation of the Chemopreventative Potency of Oxidized Lycopene in Breast-Cancer Cell Lines.Bangalore Prabhashankar Arathi et al.Journal of agricultural and food chemistry, 66(43), 11362-11371 (2018-09-28) Icariin Improves the Viability and Function of Cryopreserved Human Nucleus Pulposus-Derived Mesenchymal Stem Cells.Sheng Chen et al.Oxidative medicine and cellular longevity, 2018, 3459612-3459612 (2018-07-28) Short-term salinity stress in tobacco plants leads to the onset of animal-like PCD hallmarks in planta in contrast to long-term stress.Efthimios A Andronis et al.Planta, 231(2), 437-448 (2009-11-26) Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer.Kirtee D Wani et al.PloS one, 9(9), e107315-e107315 (2014-10-01) Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells.Bo Li et al.International journal of molecular medicine, 36(1), 53-64 (2015-05-06) The mechanism of UVB irradiation induced-apoptosis in cataract.Yinghong Ji et al.Molecular and cellular biochemistry, 401(1-2), 87-95 (2014-12-03) The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells.Ana Reis-Mendes et al.Biomolecules, 9(3) (2019-03-14) Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers.Liu Yang et al.Stem cells and development, 29(13), 835-852 (2020-04-08) Baicalein protects PC12 cells from Aβ25-35-induced cytotoxicity via inhibition of apoptosis and metabolic disorders.Li Gao et al.Life sciences, 248, 117471-117471 (2020-03-01) Methamphetamine Causes Photoreceptor Cell Damage Through Promoting Polarization of Macrophages and Inducing Inflammatory Response.Aihui Zhang et al.International journal of toxicology, 36(5), 403-409 (2017-07-22) Modulation of the Astrocyte-Neuron Lactate Shuttle System contributes to Neuroprotective action of Fibroblast Growth Factor 21.Yan Sun et al.Theranostics, 10(18), 8430-8445 (2020-07-30) Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats.Isamu Murata et al.Annals of intensive care, 7(1), 90-90 (2017-09-06) Knockdown of lncRNA SNHG1 alleviates oxygen-glucose deprivation/reperfusion-induced cell death by serving as a ceRNA for miR-424 in SH-SY5Y cells.Lixun Hu et al.Neurological research, 42(1), 47-54 (2020-01-05) Angelica sinensis polysaccharide prevents mitochondrial apoptosis by regulating the Treg/Th17 ratio in aplastic anemia.Zetao Chen et al.BMC complementary medicine and therapies, 20(1), 192-192 (2020-06-24) Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro.Nadiah Abu et al.PloS one, 9(10), e105244-e105244 (2014-10-07) Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.Zhenyu Zhu et al.Frontiers in pharmacology, 11, 94-94 (2020-03-11) Photodynamic effects on Fonsecaea monophora conidia and RAW264.7 in vitro.Xiuwen Yi et al.Journal of photochemistry and photobiology. B, Biology, 176, 112-117 (2017-10-11) Irisin Protects Heart Against Ischemia-Reperfusion Injury Through a SOD2-Dependent Mitochondria Mechanism.Zhen Wang et al.Journal of cardiovascular pharmacology, 72(6), 259-269 (2018-07-07) Resveratrol Suppresses Rotenone-induced Neurotoxicity Through Activation of SIRT1/Akt1 Signaling Pathway.Hui Wang et al.Anatomical record (Hoboken, N.J. : 2007), 301(6), 1115-1125 (2018-01-20) Enhanced Generation of Non-Oxygen Dependent Free Radicals by Schottky-type Heterostructures of Au-Bi2S3 Nanoparticles via X-ray-Induced Catalytic Reaction for Radiosensitization.Xin Wang et al.ACS nano, 13(5), 5947-5958 (2019-04-11) Tacrine derivatives stimulate human glioma SF295 cell death and alter important proteins related to disease development: An old drug for new targets.Fernanda Costa Nunes et al.Biochimica et biophysica acta, 1862(7), 1527-1536 (2018-04-29) Mst1 overexpression combined with Yap knockdown augments thyroid carcinoma apoptosis via promoting MIEF1-related mitochondrial fission and activating the JNK pathway.Xiaoli Zhang et al.Cancer cell international, 19, 143-143 (2019-05-30) LTBP2 knockdown and oxidative stress affect glaucoma features including TGFβ pathways, ECM genes expression and apoptosis in trabecular meshwork cells.Fatemeh Suri et al.Gene, 673, 70-81 (2018-06-17) Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models.Ying Li et al.Oncotarget, 9(2), 2158-2174 (2018-02-09) Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.Manzhao Ouyang et al.International journal of oncology, 54(4), 1376-1386 (2019-04-11) Melatonin fine-tunes intracellular calcium signals and eliminates myocardial damage through the IP3R/MCU pathways in cardiorenal syndrome type 3.Jin Wang et al.Biochemical pharmacology, 174, 113832-113832 (2020-02-02) Indomethacin elicits proteasomal dysfunctions develops apoptosis through mitochondrial abnormalities.Ayeman Amanullah et al.Journal of cellular physiology, 233(2), 1685-1699 (2017-07-07) Recovery of adriamycin induced mitochondrial dysfunction in liver by selenium.E Taskin et al.Cytotechnology, 67(6), 977-986 (2014-10-18) Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells.Xinchun Ding et al.Oncotarget, 8(18), 30123-30137 (2017-04-19) The pathways by which mild hypothermia inhibits neuronal apoptosis following ischemia/reperfusion injury.Chun Luo et al.Neural regeneration research, 10(1), 153-158 (2015-03-20) Type I collagen facilitates safe and reliable expansion of human dental pulp stem cells in xenogeneic serum-free culture.Mai Mochizuki et al.Stem cell research & therapy, 11(1), 267-267 (2020-07-15) IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress.Zhenchuan Liu et al.Journal of experimental & clinical cancer research : CR, 39(1), 144-144 (2020-07-31) SIN-3 as a key determinant of lifespan and its sex dependent differential role on healthspan in Caenorhabditis elegans.Renu Pandey et al.Aging, 10(12), 3910-3937 (2018-12-14) Procyanidin A2, a polyphenolic compound, exerts anti-inflammatory and anti-oxidative activity in lipopolysaccharide-stimulated RAW264.7 cells.Qin-Qin Wang et al.PloS one, 15(8), e0237017-e0237017 (2020-08-07) Long non-coding RNA GHET1/miR-105/RAP2B axis regulates the progression of acute myeloid leukemia.Yue Xiao et al.Journal of Cancer, 11(23), 7081-7090 (2020-10-31) The Protective Effect of DiDang Tang Against AlCl3-Induced Oxidative Stress and Apoptosis in PC12 Cells Through the Activation of SIRT1-Mediated Akt/Nrf2/HO-1 Pathway.Jing Lu et al.Frontiers in pharmacology, 11, 466-466 (2020-05-07) Molecular cloning, characterization and expression analysis of (B-cell lymphoma-2) Bcl-2 in the orange-spotted grouper (Epinephelus coioides).Sheng-Wei Luo et al.Developmental and comparative immunology, 76, 150-162 (2017-06-14) Activation of Sigma-1 Receptor by Cutamesine Attenuates Neuronal Apoptosis by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in a Rat Model of Asphyxia Cardiac Arrest.Jiahong Qin et al.Shock (Augusta, Ga.), 51(1), 105-113 (2018-02-10) TCDD-induced mitochondrial superoxide production does not lead to mitochondrial degeneration or genomic instability in human SH-SY5Y neuroblastoma cells.Jukka Luukkonen et al.Toxicology in vitro : an international journal published in association with BIBRA, 44, 213-218 (2017-07-05) The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIPL.Min Ho Han et al.Biomolecules & therapeutics, 23(1), 31-38 (2015-01-17) Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.Qianlin Song et al.Cell cycle (Georgetown, Tex.), 19(20), 2600-2610 (2020-09-02) Effect of γ-oryzanol on testicular degeneration induced by scrotal insulation in rams.Eduarda Escobar et al.Theriogenology, 128, 167-175 (2019-02-18) iTRAQ-based secretome reveals that SiO2 induces the polarization of RAW264.7 macrophages by activation of the NOD-RIP2-NF-κB signaling pathway.Rong Fu et al.Environmental toxicology and pharmacology, 63, 92-102 (2018-09-07) Effects of dietary tributyrin on intestinal mucosa development, mitochondrial function and AMPK-mTOR pathway in weaned pigs.Chunchun Wang et al.Journal of animal science and biotechnology, 10, 93-93 (2019-12-04) NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells.Rama P Kotipatruni et al.Oncotarget, 6(19), 17594-17604 (2015-06-09) Targeting PDK4 inhibits breast cancer metabolism.Maheedhara R Guda et al.American journal of cancer research, 8(9), 1725-1738 (2018-10-17) Radiosensitization to X-ray radiation by telomerase inhibitor MST-312 in human hepatoma HepG2 cells.Yali Wang et al.Life sciences, 123, 43-50 (2015-01-18) Anti-amyloidogenic properties of an ethyl acetate fraction from Actinidia arguta in Aβ1-42-induced ICR mice.Jeong Su Ha et al.Food & function, 9(6), 3264-3277 (2018-05-23) KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.Zhi-Chuan Zhu et al.Oncogene, 37(22), 2936-2952 (2018-03-10) Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS.Hui Liu et al.Journal of leukocyte biology, 108(1), 253-266 (2020-04-10) Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.Pei-Feng Liu et al.Theranostics, 8(3), 830-845 (2018-01-19) Resveratrol ameliorates disorders of mitochondrial biogenesis and dynamics in a rat chronic ocular hypertension model.Xi Zhang et al.Life sciences, 207, 234-245 (2018-06-13) Pyoluteorin induces cell cycle arrest and apoptosis in human triple-negative breast cancer cells MDA-MB-231.Ting Ding et al.The Journal of pharmacy and pharmacology, 72(7), 969-978 (2020-04-05) Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.Verónica Gómez-Pérez et al.European journal of medicinal chemistry, 89, 362-369 (2014-12-03) Development of apoptosis-inducing polypeptide via simultaneous mitochondrial membrane disruption and Ca2+ delivery.JongHoon Ha et al.Biomaterials, 197, 51-59 (2019-01-15) Runting and Stunting Syndrome Is Associated With Mitochondrial Dysfunction in Sex-Linked Dwarf Chicken.Hongmei Li et al.Frontiers in genetics, 10, 1337-1337 (2020-02-06) Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.Min Chul Kim et al.International journal of molecular medicine, 33(6), 1657-1663 (2014-03-22) 4-Nerolidylcatechol: apoptosis by mitochondrial mechanisms with reduction in cyclin D1 at G0/G1 stage of the chronic myelogenous K562 cell line.Polyana Lopes Benfica et al.Pharmaceutical biology, 55(1), 1899-1908 (2017-06-24) Engeletin suppresses lung cancer progression by inducing apoptotic cell death through modulating the XIAP signaling pathway: A molecular mechanism involving ER stress.Ting Liu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 128, 110221-110221 (2020-05-25) Surgery/Anesthesia disturbs mitochondrial fission/fusion dynamics in the brain of aged mice with postoperative delirium.Yayuan Lu et al.Aging, 12(1), 844-865 (2020-01-14) KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria.Elinor Hortle et al.Scientific reports, 9(1), 6356-6356 (2019-04-25) Effect of docetaxel-loaded lipid microbubble in combination with ultrasound-triggered microbubble destruction on the growth of a gastric cancer cell line.Bin Lai et al.Oncology letters, 18(1), 442-448 (2019-07-11) Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats.Yan Hui et al.Acta histochemica, 119(4), 392-399 (2017-04-25) Maslinic acid activates mitochondria-dependent apoptotic pathway in cardiac carcinoma.Tingmin Chang et al.Clinical and investigative medicine. Medecine clinique et experimentale, 37(4), E217-E224 (2014-08-05) Chronology of cellular events related to mitochondrial burnout leading to cell death in Fuchs endothelial corneal dystrophy.Sébastien J Méthot et al.Scientific reports, 10(1), 5811-5811 (2020-04-04) 2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway.Ruolin Chen et al.Industrial health, 53(3), 222-235 (2015-03-06) Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation.Bei Yan et al.Experimental and therapeutic medicine, 20(4), 3051-3063 (2020-08-29) The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer.Xiaohong Xie et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(9), 7185-7194 (2015-04-22) Ascorbyl stearate and ionizing radiation potentiate apoptosis through intracellular thiols and oxidative stress in murine T lymphoma cells.Shirish D Mane et al.Chemico-biological interactions, 281, 37-50 (2017-12-24) Multinucleated polyploid cardiomyocytes undergo an enhanced adaptability to hypoxia via mitophagy.Yun-Han Jiang et al.Journal of molecular and cellular cardiology, 138, 115-135 (2019-11-30) Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice.Belén Mollá et al.Frontiers in molecular neuroscience, 10, 264-264 (2017-09-16) Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy.Hua Bai et al.Neurochemistry international, 134, 104671-104671 (2020-01-12) Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate.Jarmila Navrátilová et al.Journal of cellular and molecular medicine, 21(9), 1859-1869 (2017-03-01) LncRNA-uc.40 silence promotes P19 embryonic cells differentiation to cardiomyocyte via the PBX1 gene.Rongqiang Wu et al.In vitro cellular & developmental biology. Animal, 54(8), 600-609 (2018-08-17) Effect of Aruncus dioicus var. kamtschaticus Extract on Neurodegeneration Improvement: Ameliorating Role in Cognitive Disorder Caused by High-Fat Diet Induced Obesity.Su Bin Park et al.Nutrients, 11(6) (2019-06-20) The Edible Marine Alga Gracilariopsis chorda Alleviates Hypoxia/Reoxygenation-Induced Oxidative Stress in Cultured Hippocampal Neurons.Md Mohibbullah et al.Journal of medicinal food, 18(9), 960-971 (2015-06-25) Involvement of TREK-1 Channel in Cell Viability of H9c2 Rat Cardiomyoblasts Affected by Bupivacaine and Lipid Emulsion.Jun Ho Yang et al.Cells, 8(5) (2019-05-17) Diethyl citrate and sodium citrate reduce the cytotoxic effects of nanosized hydroxyapatite crystals on mouse vascular smooth muscle cells.Chong-Yu Zhang et al.International journal of nanomedicine, 12, 8511-8525 (2017-12-15) Icariside II inhibits tumorigenesis via inhibiting AKT/Cyclin E/ CDK 2 pathway and activating mitochondria-dependent pathway.Ya-Sai Sun et al.Pharmacological research, 152, 104616-104616 (2019-12-31) Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes.Dmitry E Andreev et al.Genome biology, 16, 90-90 (2015-05-07) Total flavones of Dracocephalum moldavica L. protect astrocytes against H2O2-induced apoptosis through a mitochondria-dependent pathway.Rui-Fang Zheng et al.BMC complementary medicine and therapies, 20(1), 78-78 (2020-03-14) Oxidative stress and cell cycle arrest induced by short-term exposure to dustfall PM2.5 in A549 cells.Jie Yang et al.Environmental science and pollution research international, 25(23), 22408-22419 (2017-11-04) Taxifolin synergizes Andrographolide-induced cell death by attenuation of autophagy and augmentation of caspase dependent and independent cell death in HeLa cells.Mazen Alzaharna et al.PloS one, 12(2), e0171325-e0171325 (2017-02-10) LncRNA FOXP4-AS1 is activated by PAX5 and promotes the growth of prostate cancer by sequestering miR-3184-5p to upregulate FOXP4.Xingcheng Wu et al.Cell death & disease, 10(7), 472-472 (2019-06-19) A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis.Jessica K T Sousa et al.Parasitology international, 73, 101966-101966 (2019-07-31) Mitochondrial delivery of antisense RNA by MITO-Porter results in mitochondrial RNA knockdown, and has a functional impact on mitochondria.Ryo Furukawa et al.Biomaterials, 57, 107-115 (2015-04-29) Pyocyanin induces NK92 cell apoptosis via mitochondrial damage and elevated intracellular Ca2.Ting Li et al.Innate immunity, 25(1), 3-12 (2018-11-15) Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action.Anissa Nofita Sari et al.Cancers, 12(5) (2020-05-10) 7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress.Suk Ju Cho et al.Biomolecules & therapeutics, 27(1), 85-91 (2018-11-30) Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells.Ajda Çoker-Gürkan et al.Amino acids, 47(1), 87-100 (2014-10-15) Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro.Shigeru Murakami et al.Amino acids, 50(9), 1279-1288 (2018-06-28) Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits.Jing Wu et al.Journal of neuroinflammation, 17(1), 110-110 (2020-04-12) Autophagy activation promotes removal of damaged mitochondria and protects against renal tubular injury induced by albumin overload.Jin Tan et al.Histology and histopathology, 33(7), 681-690 (2018-01-11) Intravenous administration of mitochondria for treating experimental Parkinson's disease.Xianxun Shi et al.Mitochondrion, 34, 91-100 (2017-03-01) Wogonoside promotes apoptosis in gastric cancer AGS and SGC-7901 cells through induction of mitochondrial dysfunction and endoplasmic reticulum stress.Xiao-Miao Hu et al.FEBS open bio, 9(8), 1469-1476 (2019-06-30) Trans, trans-2,4-decadienal (tt-DDE), a composition of cooking oil fumes, induces oxidative stress and endoplasmic reticulum stress in human corneal epithelial cells.Chenxi Yan et al.Toxicology in vitro : an international journal published in association with BIBRA, 68, 104933-104933 (2020-07-12) The effect of recombinant human growth hormone and insulin-like growth factor-1 on the mitochondrial function and viability of peripheral blood mononuclear cells in vitro.James Keane et al.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 40(2), 105-115 (2014-12-23) Long non-coding RNA LINC01419 mediates miR-519a-3p/PDRG1 axis to promote cell progression in osteosarcoma.Zhiqian Gu et al.Cancer cell international, 20, 147-147 (2020-05-12) Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells.Marina Figliuzzi et al.Archives of toxicology, 94(9), 2965-2979 (2020-06-25) Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential.He Liu et al.Cell death and differentiation, 26(6), 1048-1061 (2018-08-30) Polyphenol-Conjugated Bimetallic Au@AgNPs for Improved Wound Healing.Piotr Orlowski et al.International journal of nanomedicine, 15, 4969-4990 (2020-08-09) Transition metals activate TFEB in overexpressing cells.Karina A Peña et al.The Biochemical journal, 470(1), 65-76 (2015-08-08) Nucleobase-modified polyamidoamine-mediated miR-23b delivery to inhibit the proliferation and migration of lung cancer.Haobo Han et al.Biomaterials science, 5(11), 2268-2275 (2017-10-05) Oridonin exhibits anti-angiogenic activity in human umbilical vein endothelial cells by inhibiting VEGF-induced VEGFR-2 signaling pathway.Jin-Huan Jiang et al.Pathology, research and practice, 216(8), 153031-153031 (2020-07-25) Hippo/Mst1 overexpression induces mitochondrial death in head and neck squamous cell carcinoma via activating β-catenin/Drp1 pathway.Chao Ma et al.Cell stress & chaperones, 24(4), 807-816 (2019-05-28) Hydroxy-α-sanshool Possesses Protective Potentials on H2O2-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway.Ruo-Lan Li et al.Oxidative medicine and cellular longevity, 2020, 3481758-3481758 (2020-07-23) The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells.Ewa Augustin et al.Acta pharmacologica Sinica, 36(3), 385-399 (2015-02-03) Mitoxantrone as photothermal agents for ultrasound/fluorescence imaging-guided chemo-phototherapy enhanced by intratumoral H2O2-Induced CO.Ya Wang et al.Biomaterials, 252, 120111-120111 (2020-05-19) Mn-TAT PTD-Ngb ameliorates inflammation through the elimination of damaged mitochondria and the activation of Nrf2-antioxidant signaling pathway.Cui Zhang et al.Biochemical pharmacology, 178, 114055-114055 (2020-05-30) A Polysaccharide Purified from Morchella conicaPers. Prevents Oxidative Stress Induced by H₂O₂ in Human Embryonic Kidney (HEK) 293T Cells.Na Xu et al.International journal of molecular sciences, 19(12) (2018-12-16) Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27.Sung Won Lee et al.Bone research, 6, 20-20 (2018-07-14) Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells.Shuangyue Li et al.Industrial health, 55(2), 108-118 (2016-11-15) Transcranial low-level laser therapy improves brain mitochondrial function and cognitive impairment in D-galactose-induced aging mice.Farzad Salehpour et al.Neurobiology of aging, 58, 140-150 (2017-07-25) PERK pathway is involved in oxygen-glucose-serum deprivation-induced NF-kB activation via ROS generation in spinal cord astrocytes.Jinbo Liu et al.Biochemical and biophysical research communications, 467(2), 197-203 (2015-10-11) Attenuation of cyclosporine A induced nephrotoxicity by schisandrin B through suppression of oxidative stress, apoptosis and autophagy.Qiao Lai et al.International immunopharmacology, 52, 15-23 (2017-08-29) Development of erianin-loaded dendritic mesoporous silica nanospheres with pro-apoptotic effects and enhanced topical delivery.Canlong Mo et al.Journal of nanobiotechnology, 18(1), 55-55 (2020-04-02) Potent hydrazone derivatives targeting esophageal cancer cells.Ling-Yu Li et al.European journal of medicinal chemistry, 148, 359-371 (2018-02-24) Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes.Guoyuan Qi et al.Biochimica et biophysica acta, 1863(6), 549-562 (2018-03-05) Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells.Zhifei Shao et al.Translational research : the journal of laboratory and clinical medicine, 166(1), 89-102 (2015-01-15) Zinc and calcium modulate mitochondrial redox state and morphofunctional integrity.Mahmoud S Sharaf et al.Free radical biology & medicine, 84, 142-153 (2015-04-07) Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.Wen Sun et al.Free radical biology & medicine, 108, 433-444 (2017-04-18) Overexpression of miR‑30c‑5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5.Xin Wang et al.International journal of molecular medicine, 45(2), 375-384 (2020-01-03) p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.Sian M Henson et al.The Journal of clinical investigation, 124(9), 4004-4016 (2014-08-02) Taurine protects HK-2 cells from oxidized LDL-induced cytotoxicity via the ROS-mediated mitochondrial and p53-related apoptotic pathways.Chun-Yu Chang et al.Toxicology and applied pharmacology, 279(3), 351-363 (2014-07-16) Quantitative proteomics reveals mitochondrial respiratory chain as a dominant target for carbon ion radiation: Delayed reactive oxygen species generation caused DNA damage.Peng-Cheng Fan et al.Free radical biology & medicine, 130, 436-445 (2018-11-06) IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.Jung Hyun Park et al.Redox biology, 17, 16-24 (2018-04-17) MicroRNA-7450 regulates non-thermal plasma-induced chicken Sertoli cell apoptosis via adenosine monophosphate-activated protein kinase activation.Jiao Jiao Zhang et al.Scientific reports, 8(1), 8761-8761 (2018-06-10)

Remarks