Boiling point	50-51 ºC (0.5 Torr)**
Flash point	100.9±9.9 ºC, 计算值*
Density	1.044±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Peer-Reviewed Papers

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid.M A Lovell et al.Archives of neurology, 58(3), 392-396 (2001-03-20) Interactions between metal ions and carbohydrates. Syntheses and spectroscopic studies of several lanthanide nitrate-D-galactitol complexes.Lei Yu et al.Carbohydrate research, 346(14), 2278-2284 (2011-07-26) Radioimmunoassay of serum glycocholic acid, standard laboratory tests of liver function and liver biopsy findings: comparative study of children with liver disease.A Matsui et al.Journal of clinical pathology, 35(9), 1011-1017 (1982-09-01) Galactose toxicity in animals.Kent Lai et al.IUBMB life, 61(11), 1063-1074 (2009-10-28) Galactitol and galactonate in red blood cells of children with the Duarte/galactosemia genotype.Can Ficicioglu et al.Molecular genetics and metabolism, 84(2), 152-159 (2005-01-27) Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer's disease.M A Raskind et al.Biological psychiatry, 46(6), 756-765 (1999-09-24) Serum cobalamin and methylmalonic acid in Alzheimer dementia.M O Kristensen et al.Acta neurologica Scandinavica, 87(6), 475-481 (1993-06-01) Selective oxidation and reduction reactions with cofactor regeneration mediated by galactitol-, lactate-, and formate dehydrogenases immobilized on magnetic nanoparticles.Ayhan S Demir et al.Journal of biotechnology, 152(4), 176-183 (2011-03-12) Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.J A Molina et al.Journal of neural transmission (Vienna, Austria : 1996), 109(7-8), 1035-1044 (2002-07-12) Galactitol is not a cause of senile cataract.H Arola et al.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 230(3), 240-242 (1992-01-01) Long-term complications in Estonian galactosemia patients with a less strict lactose-free diet and metabolic control.K Krabbi et al.Molecular genetics and metabolism, 103(3), 249-253 (2011-04-20) Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease.H U Shetty et al.Clinical chemistry, 42(2), 298-302 (1996-02-01) Production of hexanoic acid from D-galactitol by a newly isolated Clostridium sp. BS-1.Byoung Seung Jeon et al.Applied microbiology and biotechnology, 88(5), 1161-1167 (2010-08-20) Okibacterium endophyticum sp. nov., a novel endophytic actinobacterium isolated from roots of Salsola affinis C. A. Mey.Hong-Fei Wang et al.Antonie van Leeuwenhoek, 107(3), 835-843 (2015-01-09) Evaluation of the biodegradability of polyurethane and its derivatives by using lipase-displaying arming yeast.Seiji Shibasaki et al.Biocontrol science, 14(4), 171-175 (2010-01-09) In vitro and in vivo aldose reductase inhibitory activity of standardized extracts and the major constituent of Andrographis paniculata.Ciddi Veeresham et al.Phytotherapy research : PTR, 27(3), 412-416 (2012-05-26) Outcomes of siblings with classical galactosemia.Joanne Hughes et al.The Journal of pediatrics, 154(5), 721-726 (2009-02-03) Leaf-cutter ant fungus gardens are biphasic mixed microbial bioreactors that convert plant biomass to polyols with biotechnological applications.Alexandre F Somera et al.Applied and environmental microbiology, 81(13), 4525-4535 (2015-04-26) Two new compounds from the dried tender stems of Cinnamomum cassia.Chao Liu et al.Journal of Asian natural products research, 11(9), 845-849 (2010-02-26) Duarte galactosemia: how sweet is it?Paul M Fernhoff Clinical chemistry, 56(7), 1045-1046 (2010-05-22) Polyol formation in cell lines of rat retinal capillary pericytes and endothelial cells (TR-rPCT and TR-iBRB).Peter F Kador et al.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 25(4), 299-308 (2009-05-20) Galactose metabolism by the mouse with galactose-1-phosphate uridyltransferase deficiency.C Ning et al.Pediatric research, 48(2), 211-217 (2000-08-06) The triterpenes 3β-lup-20(29)-en-3-ol and 3β-lup-20(29)-en-3-yl acetate and the carbohydrate 1,2,3,4,5,6-hexa-O-acetyl-dulcitol as photosynthesis light reactions inhibitors.Djalma Menezes-de-Oliveira et al.Molecules (Basel, Switzerland), 16(12), 9939-9956 (2011-12-03) Metabolic fingerprints of proliferative diabetic retinopathy: an 1H-NMR-based metabonomic approach using vitreous humor.Ignasi Barba et al.Investigative ophthalmology & visual science, 51(9), 4416-4421 (2010-04-09) The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease.M L Selley et al.Neurobiology of aging, 23(3), 383-388 (2002-04-18) Differential acetylcholine and choline concentrations in the cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia.Jian-ping Jia et al.Chinese medical journal, 117(8), 1161-1164 (2004-09-14) Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease.J-M Serot et al.Journal of neurology, neurosurgery, and psychiatry, 76(11), 1585-1587 (2005-10-18) Polyol formation in cell lines of rat retinal capillary pericytes and endothelial cells (TR-rPCT and TR-iBRB).Peter F Kador et al.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 25(4), 299-308 (2009-05-20) Oxidative stress in lens in vivo: inhibitory effect of caffeine. A preliminary report.S D Varma et al.Molecular vision, 16, 501-505 (2010-03-31) In vivo evidence of brain galactitol accumulation in an infant with galactosemia and encephalopathy.G T Berry et al.The Journal of pediatrics, 138(2), 260-262 (2001-02-15) 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.Atsushi Kato et al.Bioorganic & medicinal chemistry letters, 20(19), 5630-5633 (2010-09-02) Galactose and galactitol in the urine of children with compound heterozygosity for Duarte variant and classical galactosemia (GtD/gt) after an oral galactose load.H P Schwarz et al.Clinical chemistry, 31(3), 420-422 (1985-03-01) Erythrocyte galactose 1-phosphate quantified by isotope-dilution gas chromatography-mass spectrometry.Jie Chen et al.Clinical chemistry, 48(4), 604-612 (2002-03-20) Galactitol and galactonate in red blood cells of galactosemic patients.Claire T Yager et al.Molecular genetics and metabolism, 80(3), 283-289 (2003-12-19) Capillary gas chromatography combined with ion trap detection for quantitative profiling of polyols in cerebrospinal fluid and plasma.H U Shetty et al.Analytical biochemistry, 224(1), 279-285 (1995-01-01) The analysis of hexitols in biological fluid by selected ion monitoring.B R Pettit et al.Biomedical mass spectrometry, 7(7), 309-313 (1980-07-01) The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum.Sri Fatmawati et al.Phytotherapy research : PTR, 23(1), 28-32 (2008-12-25) Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease.Beatrice Bocca et al.Annali dell'Istituto superiore di sanita, 41(2), 197-203 (2005-10-26) Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates.Andreas Bosshart et al.Chembiochem : a European journal of chemical biology, 16(4), 592-601 (2015-02-07) The effect of aldose reductase inhibition on erythrocyte polyols and galactitol accumulation in diabetic patients.C M Airey et al.Diabetic medicine : a journal of the British Diabetic Association, 6(9), 804-808 (1989-12-01) Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.Anna Walter et al.Neurobiology of aging, 25(10), 1299-1303 (2004-10-07) Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects.A N Fonteh et al.Amino acids, 32(2), 213-224 (2006-10-13) ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.Daniel J Wichelecki et al.The Journal of biological chemistry, 290(48), 28963-28976 (2015-10-17) Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.Wolfram Gronwald et al.Kidney international, 79(11), 1244-1253 (2011-03-11) Galactitol in galactosemia.C Jakobs et al.European journal of pediatrics, 154(7 Suppl 2), S50-S52 (1995-01-01) Gas-liquid chromatographic determination of galactitol in amniotic fluid for possible use in prenatal diagnosis of galactosaemia.J T Allen et al.Clinica chimica acta; international journal of clinical chemistry, 110(1), 59-63 (1981-02-19) Features and outcome of galactokinase deficiency in children diagnosed by newborn screening.Julia B Hennermann et al.Journal of inherited metabolic disease, 34(2), 399-407 (2011-02-04) Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease.Takashi Abe et al.Journal of neuroscience research, 70(3), 447-450 (2002-10-23) Reversible and efficient inhibition of UDP-galactopyranose mutase by electrophilic, constrained and unsaturated UDP-galactitol analogues.Christophe Ansiaux et al.Chemistry (Weinheim an der Bergstrasse, Germany), 18(46), 14860-14866 (2012-09-28) [Optimal extraction of melampyrit from Euonymus fortunei by central composite design-response surface methodology].Wen-Jun Wei et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(6), 972-974 (2009-09-22) Single-step bioconversion for the preparation of L-gulose and L-galactose.Ryan D Woodyer et al.Carbohydrate research, 345(3), 363-368 (2009-12-26) A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.Richard F G Fröhlich et al.Bioorganic & medicinal chemistry letters, 21(22), 6872-6875 (2011-10-07) Comosusols A-D and comosone A: cytotoxic compounds from the brown alga Sporochnus comosus.Simon P B Ovenden et al.Journal of natural products, 74(4), 739-743 (2011-02-26) Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia.K J Bär et al.Neurobiology of aging, 24(2), 333-338 (2002-12-25) Identification of the galactitol dehydrogenase, LadB, that is part of the oxido-reductive D-galactose catabolic pathway in Aspergillus niger.Dominik Mojzita et al.Fungal genetics and biology : FG & B, 49(2), 152-159 (2011-12-14) Duarte (DG) galactosemia: a pilot study of biochemical and neurodevelopmental assessment in children detected by newborn screening.Can Ficicioglu et al.Molecular genetics and metabolism, 95(4), 206-212 (2008-11-04) The effect of dietary fruits and vegetables on urinary galactitol excretion in galactose-1-phosphate uridyltransferase deficiency.G T Berry et al.Journal of inherited metabolic disease, 16(1), 91-100 (1993-01-01) Ultrasonic-assisted liquid-liquid extraction and HILIC-ELSD analysis of ginsenoside Rb(1), astragaloside IV and dulcitol in sugar-free "Fufangfufangteng Heji".Jieping Qin et al.Journal of pharmaceutical and biomedical analysis, 56(4), 836-840 (2011-08-16) Spatial Variation and Survival of Salmonella enterica Subspecies in a Population of Australian Sleepy Lizards (Tiliqua rugosa).Sandra K Parsons et al.Applied and environmental microbiology, 81(17), 5804-5811 (2015-06-21) [Familial cataract in plasma galactitol increase without known enzyme defect].M Budde et al.Klinische Monatsblatter fur Augenheilkunde, 215(4), 255-257 (1999-11-26) Determination of polyols in serum by selected ion monitoring.J Roboz et al.Clinical chemistry, 30(10), 1611-1615 (1984-10-01) Monitoring of biochemical status in children with Duarte galactosemia: utility of galactose, galactitol, galactonate, and galactose 1-phosphate.Can Ficicioglu et al.Clinical chemistry, 56(7), 1177-1182 (2010-05-22) Stable isotope dilution analysis of galactitol in amniotic fluid: an accurate approach to the prenatal diagnosis of galactosemia.C Jakobs et al.Pediatric research, 18(8), 714-718 (1984-08-01) In vitro and in vivo inhibitory activities of four Indian medicinal plant extracts and their major components on rat aldose reductase and generation of advanced glycation endproducts.Ajmeera Rama Rao et al.Phytotherapy research : PTR, 27(5), 753-760 (2012-07-25) The Landscape of Adaptive Evolution of a Gut Commensal Bacteria in Aging Mice.Hugo C Barreto et al.Current biology : CB, 30(6), 1102-1109 (2020-03-07) Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry.C Ning et al.Metabolism: clinical and experimental, 49(11), 1460-1466 (2000-11-25)

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