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Peer-Reviewed Papers

Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction.Carola Buccellati et al.European journal of pharmacology, 443(1-3), 133-141 (2002-06-05) Bacillus thermoamyloliquefaciens KP1071 alpha-glucosidase II is a thermostable M(r) 540,000 homohexameric alpha-glucosidase with both exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities.Y Suzuki et al.European journal of biochemistry, 245(1), 129-136 (1997-04-01) Design, synthesis and in vitro activities on anti-platelet aggregation of 4-methoxybenzene-1,3-isophthalamides.Xiu Jie Liu et al.Bioorganic & medicinal chemistry letters, 22(21), 6591-6595 (2012-09-27) Thermal analysis as a screening technique in preformulation studies of picotamide solid dosage forms.P Mura et al.Drug development and industrial pharmacy, 24(8), 747-756 (1999-01-07) The effects of thromboxane A2 inhibition (picotamide) and angiotensin II receptor blockade (losartan) in primary Raynaud's phenomenon.P Pancera et al.Journal of internal medicine, 242(5), 373-376 (1998-01-04) "In vitro" and "ex vivo" effects of picotamide, a combined thromboxane A2-synthase inhibitor and -receptor antagonist, on human platelets.M Berrettini et al.European journal of clinical pharmacology, 39(5), 495-500 (1990-01-01) Inhibition of agonist-induced smooth muscle contraction by picotamide in the male human lower urinary tract outflow region.Martin Hennenberg et al.European journal of pharmacology, 803, 39-47 (2017-03-21) Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor.P L Malini et al.Lancet (London, England), 350(9070), 15-18 (1997-07-05) Medical management of peripheral arterial disease.Daniel G Hackam JAMA, 296(1), 41-41 (2006-07-06) Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes.S Ratti et al.European journal of pharmacology, 355(1), 77-83 (1998-10-01) Picotamide in migraine aura prevention: a pilot study.G Allais et al.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 25 Suppl 3, S267-S269 (2004-11-19) Tumor necrosis factor-induced lethal hepatitis: pharmacological intervention with verapamil, tannic acid, picotamide and K76COOH.W Van Molle et al.FEBS letters, 467(2-3), 201-205 (2000-02-17) Treatment of aura: solving the puzzle.G D'Andrea et al.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 27 Suppl 2, S96-S99 (2006-05-12) 8-isoprostane F2α up-regulates the expression of type 5 phosphodiesterase in cavernosal vascular smooth muscle cells: inhibition with sildenafil, iloprost, nitric oxide and picotamide.Matthew Hotston et al.BJU international, 106(11), 1794-1798 (2010-05-27) Isolation of phosphopeptides by immobilized metal ion affinity chromatography.Thomas Nühse et al.Current protocols in molecular biology, Chapter 18, Unit 18-Unit 18 (2008-02-12) Picotamide versus aspirin in diabetic patients with peripheral arterial disease: has David defeated Goliath?Paolo Gresele et al.European heart journal, 25(20), 1769-1771 (2004-10-12) Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study.Gian Gastone Neri Serneri et al.European heart journal, 25(20), 1845-1852 (2004-10-12) Antivasoconstrictor and antiaggregatory activities of picotamide unrelated to thromboxane A2 antagonism.R Vezza et al.Thrombosis and haemostasis, 78(5), 1385-1391 (1998-01-04) Antiaggregatory effects of picotamide in long-term treatment: a 2-year, double-blind placebo-controlled trial.M Cocozza et al.Vascular medicine (London, England), 2(4), 292-295 (1998-05-12) Effects of aspirin or picotamide, an antithromboxane agent, in combination with low-intensity oral anticoagulation in patients with acute myocardial infarction: a controlled randomized pilot trial.A Vetrano et al.Giornale italiano di cardiologia, 29(5), 524-528 (1999-06-15) The receptor antagonist picotamide inhibits adrenergic and thromboxane-induced contraction of hyperplastic human prostate smooth muscle.Martin Hennenberg et al.American journal of physiology. Renal physiology, 305(10), F1383-F1390 (2013-09-21) Dietary polyunsaturated fatty acid and antioxidant modulation of vascular dysfunction in the spontaneously hypertensive rat.M Y Abeywardena et al.Prostaglandins, leukotrienes, and essential fatty acids, 65(2), 91-97 (2001-09-08) Physical characterization of picotamide monohydrate and anhydrous picotamide.G Bettinetti et al.Journal of pharmaceutical sciences, 88(11), 1133-1139 (1999-11-17) A review of picotamide in the reduction of cardiovascular events in diabetic patients.Andrea Celestini et al.Vascular health and risk management, 3(1), 93-98 (2007-06-23) Competitive inhibition of platelet thromboxane A2 receptor binding by picotamide.P A Modesti et al.European journal of pharmacology, 169(1), 85-93 (1989-10-04) Determinants of fibrinogen in an Italian population suffering from claudication. Lower fibrinogen in the south compared to middle and north of Italy. The ADEP Group.S Basili et al.Haematologica, 83(8), 701-707 (1998-10-30) Thromboxane inhibition improves renal perfusion and excretory function in severe congestive heart failure.Sergio Castellani et al.Journal of the American College of Cardiology, 42(1), 133-139 (2003-07-10) Long-term safety and efficacy of picotamide, a dual-action antithromboxane agent, in diabetic patients with carotid atherosclerosis: a 6-year follow-up study.V Coto et al.The Journal of international medical research, 26(4), 200-205 (1998-11-18) Masterclass series in peripheral arterial disease. Antiplatelet therapy for peripheral arterial disease and claudication.William R Hiatt et al.Vascular medicine (London, England), 11(1), 55-60 (2006-05-04) Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patients.A Giustina et al.Diabetes, 47(3), 423-430 (1998-03-31) Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2.Serena Lucotti et al.The Journal of clinical investigation, 129(5), 1845-1862 (2019-03-26) Effects of picotamide on release of endothelin-1, thromboxane and prostacycline after treadmill stress in patients with peripheral artery disease.A Saitta et al.Angiology, 49(11), 879-884 (1998-11-20)

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