Melting point	201-204 ºC

Symbol(GHS)	Xn
Hazard Codes	R20/21/22
SDS/MSDS	S36

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Calycosin down-regulates c-Met to suppress development of glioblastomas.Xiaohu Nie et al.Journal of biosciences, 44(4) (2019-09-11) Calycosin inhibits nasopharyngeal carcinoma cells by influencing EWSAT1 expression to regulate the TRAF6-related pathways.Lingping Kong et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 106, 342-348 (2018-07-04) Calycosin protects HUVECs from advanced glycation end products-induced macrophage infiltration.Youhua Xu et al.Journal of ethnopharmacology, 137(1), 359-370 (2011-06-15) Effects of calycosin on the impairment of barrier function induced by hypoxia in human umbilical vein endothelial cells.Yi Fan et al.European journal of pharmacology, 481(1), 33-40 (2003-11-26) Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.Xingping Duan et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 25, 83-92 (2017-02-14) Effect of calycosin on left ventricular ejection fraction and angiogenesis in rat models with myocardial infarction.Gao Junqing et al.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 35(2), 160-167 (2015-05-16) Calycosin induces apoptosis in osteosarcoma cell line via ERβ‑mediated PI3K/Akt signaling pathways.Wei Tian et al.Molecular medicine reports, 21(6), 2349-2356 (2020-04-03) Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC.Jing Yan Tang et al.PloS one, 5(7), e11822-e11822 (2010-08-06) Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats.Chao Guo et al.Journal of ethnopharmacology, 144(3), 768-774 (2012-11-06) Calycosin promotes lifespan in Caenorhabditis elegans through insulin signaling pathway via daf-16, age-1 and daf-2.Lulu Lu et al.Journal of bioscience and bioengineering, 124(1), 1-7 (2017-04-25) Calycosin inhibits viability, induces apoptosis, and suppresses invasion of cervical cancer cells by upregulating tumor suppressor miR-375.Dongli Zhang et al.Archives of biochemistry and biophysics, 691, 108478-108478 (2020-07-28) Calycosin stimulates proliferation of estrogen receptor-positive human breast cancer cells through downregulation of Bax gene expression and upregulation of Bcl-2 gene expression at low concentrations.Jian Chen et al.JPEN. Journal of parenteral and enteral nutrition, 35(6), 763-769 (2011-07-30) Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae.Guang Hu et al.Xenobiotica; the fate of foreign compounds in biological systems, 42(3), 294-303 (2011-10-04) Investigation of effects and mechanisms of total flavonoids of Astragalus and calycosin on human erythroleukemia cells.Dongqing Zhang et al.Oxidative medicine and cellular longevity, 2012, 209843-209843 (2012-08-01) Thermal stability of kudzu root (Pueraria Radix) isoflavones as additives to beef patties.S Kumari et al.Journal of food science and technology, 52(3), 1578-1585 (2015-03-10) Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.Xinli Chen et al.Pharmaceutical research, 32(2), 538-548 (2014-08-22) Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract.Amy Guo-wei Gong et al.Journal of ethnopharmacology, 168, 150-157 (2015-03-23) Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins.Yan Zhou et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(7), 5333-5339 (2015-02-13) Calycosin induces apoptosis via p38‑MAPK pathway‑mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells.Wei Tian et al.Molecular medicine reports, 22(5), 3962-3968 (2020-09-10)

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