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Peer-Reviewed Papers

CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles.Daniela Ivanova et al.Cell reports, 30(7), 2444-2459 (2020-02-23) Group I Paks support muscle regeneration and counteract cancer-associated muscle atrophy.Andrea Cerquone Perpetuini et al.Journal of cachexia, sarcopenia and muscle, 9(4), 727-746 (2018-05-22) AP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets.Gregory Neveu et al.Journal of virology, 89(8), 4387-4404 (2015-02-06) Influenza A virus uses intercellular connections to spread to neighboring cells.Kari L Roberts et al.Journal of virology, 89(3), 1537-1549 (2014-11-28) Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans.Fikadu G Tafesse et al.PLoS pathogens, 11(10), e1005188-e1005188 (2015-10-03) p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112.Diana Z Ye et al.PloS one, 6(11), e27637-e27637 (2011-11-19) Productive Entry of Foot-and-Mouth Disease Virus via Macropinocytosis Independent of Phosphatidylinositol 3-Kinase.Shi-Chong Han et al.Scientific reports, 6, 19294-19294 (2016-01-14) Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice.Z Tu et al.Cell death and differentiation, 23(1), 169-181 (2015-07-18) Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis.Karla C Williams et al.Oncogene, 38(19), 3598-3615 (2019-01-18) YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells.Shannon M White et al.Developmental cell, 49(3), 425-443 (2019-05-08) A key role for Rac and Pak signaling in neutrophil extracellular traps (NETs) formation defines a new potential therapeutic target.Mathilde Gavillet et al.American journal of hematology, 93(2), 269-276 (2017-11-11) Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of merlin.Masashi Okada et al.Cancer research, 69(9), 4043-4051 (2009-04-09) Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling.Ji-Gang Zhang et al.BMC cancer, 20(1), 32-32 (2020-01-15) African swine fever virus uses macropinocytosis to enter host cells.Elena G Sánchez et al.PLoS pathogens, 8(6), e1002754-e1002754 (2012-06-22) Cdc42 Is Essential for Both Articular Cartilage Degeneration and Subchondral Bone Deterioration in Experimental Osteoarthritis.Xinhua Hu et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 33(5), 945-958 (2018-01-10) Betanodavirus-like particles enter host cells via clathrin-mediated endocytosis in a cholesterol-, pH- and cytoskeleton-dependent manner.Runqing Huang et al.Veterinary research, 48(1), 8-8 (2017-02-10) Cell confluence regulates claudin-2 expression: possible role for ZO-1 and Rac.Yasaman Amoozadeh et al.American journal of physiology. Cell physiology, 314(3), C366-C378 (2017-12-01) Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling.Kristina Kurgonaite et al.Journal of cell science, 128(20), 3781-3795 (2015-08-27) PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma.Elaine Y Chung et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 25(12), 3589-3601 (2019-03-14) PKA-dependent phosphorylation of LIMK1 and Cofilin is essential for mouse sperm acrosomal exocytosis.Ana Romarowski et al.Developmental biology, 405(2), 237-249 (2015-07-15) Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein.Magdalena Anna Krzyzaniak et al.PLoS pathogens, 9(4), e1003309-e1003309 (2013-04-18) PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.A Berger et al.Leukemia, 28(3), 629-641 (2013-11-23) Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.K Grauwet et al.Journal of virology, 90(3), 1522-1533 (2015-11-20) PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion.G Wang et al.Cell death & disease, 6, e1682-e1682 (2015-03-15) ErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.Khedidja Benseddik et al.PloS one, 8(1), e55211-e55211 (2013-02-06) Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes.András D Tóth et al.EMBO molecular medicine, 10(7) (2018-06-17) Probing Cell Adhesion Profiles with a Microscale Adhesive Choice Assay.Harsha Kittur et al.Biophysical journal, 113(8), 1858-1867 (2017-10-19) Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture.Florian Ingo Schmidt et al.The EMBO journal, 30(17), 3647-3661 (2011-07-28) Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kinase 2 phosphorylation orchestrating 2 oncogenic pathways.Hui Li et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(1), 73-82 (2017-08-27) Estimating high-risk cannabis and opiate use in Ankara, Istanbul and Izmir.Ludwig Kraus et al.Drug and alcohol review, 36(5), 626-632 (2016-06-29) Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.Hiroaki Nagai et al.EBioMedicine, 24, 147-158 (2017-09-25) Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX.Abira Rajah et al.Scientific reports, 9(1), 11430-11430 (2019-08-09) Caspase-3 activation decreases lipid order in the outer plasma membrane leaflet during apoptosis: A fluorescent probe study.Kyrylo A Pyrshev et al.Biochimica et biophysica acta, 1859(10), 2123-2132 (2017-08-09) Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.Artur Szczepanski et al.Veterinary research, 49(1), 55-55 (2018-07-05) Specific Aptamer-Based Probe for Analyzing Biomarker MCP Entry Into Singapore Grouper Iridovirus-Infected Host Cells via Clathrin-Mediated Endocytosis.Qing Yu et al.Frontiers in microbiology, 11, 1206-1206 (2020-07-09) Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala.Aniruddha Das et al.Scientific reports, 7(1), 13930-13930 (2017-10-27) Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation.Christopher S Rex et al.The Journal of cell biology, 186(1), 85-97 (2009-07-15) Oncogenic role of Merlin/NF2 in glioblastoma.P A Guerrero et al.Oncogene, 34(20), 2621-2630 (2014-07-22) Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic.H D Roberts-Dalton et al.Nanoscale, 9(36), 13693-13706 (2017-09-08) Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation.Jirong R Wang et al.Genetics, 202(3), 1055-1069 (2016-01-08)

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