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2-Methyl-5-phenylpyridine | CAS:3256-88-0
2-Methyl-5-phenylpyridine
  • Name:2-Methyl-5-phenylpyridine
  • CAS:3256-88-0
  • Synonyms:
  • Molecular Formula:C12H11N
  • Molecular Weight:169.22
  • EINESC:221-854-2

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A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy.Emma D Deeks Clinical drug investigation, 33(9), 689-697 (2013-07-25) Influence of omeprazole and famotidine on the antiplatelet effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes: a prospective, randomized, multicenter study.Hideto Yano et al.Circulation journal : official journal of the Japanese Circulation Society, 76(11), 2673-2680 (2012-08-07) Comparison of PPIs and H2-receptor antagonists plus prokinetics for dysmotility-like dyspepsia.Masahiro Sakaguchi et al.World journal of gastroenterology, 18(13), 1517-1524 (2012-04-18) Proton-pump inhibitors could be innocent when used concomitantly with clopidogrel.Hisanori Horiuchi Circulation journal : official journal of the Japanese Circulation Society, 76(11), 2542-2543 (2012-09-25) Comparison of famotidine with cimetidine and ranitidine.R R Berardi et al.Clinical pharmacy, 7(4), 271-284 (1988-04-01) Effects of 14 frequently used drugs on prostate-specific antigen expression in prostate cancer LNCaP cells.Kazuhiro Iguchi et al.Oncology letters, 7(5), 1665-1668 (2014-04-26) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Outpatient intravenous interleukin-2 with famotidine has activity in metastatic melanoma.Walter D Y Quan et al.Cancer biotherapy & radiopharmaceuticals, 27(7), 442-445 (2012-06-27) Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.Dennis J Pelletier et al.Journal of chemical information and modeling, 47(3), 1196-1205 (2007-04-13) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) Physico-chemical comparison of famotidine tablets prepared via dry granulation and direct compression techniques.Abdul Baseer et al.Pakistan journal of pharmaceutical sciences, 26(3), 439-443 (2013-04-30) [Clinical aspects of Kvamatel (famotidine) administration].V S Golochevskaia Klinicheskaia meditsina, 74(1), 45-47 (1996-01-01) The binding selectivity of vonoprazan (TAK-438) to the gastric H+, K+ -ATPase.D R Scott et al.Alimentary pharmacology & therapeutics, 42(11-12), 1315-1326 (2015-10-02) Analysis of the histamine H2-receptor in human monocytes.Kristin Werner et al.Biochemical pharmacology, 92(2), 369-379 (2014-09-10) A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.S Takayama et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(1), 41-52 (2012-03-31) Famotidine-associated central nervous system reactions and plasma and cerebrospinal drug concentrations in neurosurgical patients with renal failure.K Yoshimoto et al.Clinical pharmacology and therapeutics, 55(6), 693-700 (1994-06-01) Effects of 14 frequently used drugs on prostate-specific antigen expression in prostate cancer LNCaP cells.Kazuhiro Iguchi et al.Oncology letters, 7(5), 1665-1668 (2014-04-26) Multiple cerebral infarctions related to famotidine-induced eosinophilia.Chi-Shun Wu et al.Journal of neurology, 259(10), 2229-2231 (2012-05-16) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Famotidine: a notable lack of drug interactions.T J Humphries Scandinavian journal of gastroenterology. Supplement, 134, 55-60 (1987-01-01) Analysis of a single Helicobacter pylori strain over a 10-year period in a primate model.Hui Liu et al.International journal of medical microbiology : IJMM, 305(3), 392-403 (2015-03-26) Neural computational prediction of oral drug absorption based on CODES 2D descriptors.A Guerra et al.European journal of medicinal chemistry, 45(3), 930-940 (2009-12-22) Famotidine. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in peptic ulcer disease and other allied diseases.H D Langtry et al.Drugs, 38(4), 551-590 (1989-10-01) The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.Kin Y Tam et al.Journal of medicinal chemistry, 53(1), 392-401 (2009-12-02) Design and development of novel lipid based gastroretentive delivery system: response surface analysis, in-vivo imaging and pharmacokinetic study.Aly Ahmed Abdelbary et al.Drug delivery, 22(1), 37-49 (2013-12-20) QSAR-based solubility model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 18(19), 7078-7084 (2010-09-03) Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS).Kouichi Sakurai et al.BMC gastroenterology, 12, 42-42 (2012-05-03) Famotidine in the USA: a review of efficacy studies.G Gitnick The Journal of international medical research, 17 Suppl 1, 17A-24A (1989-01-01) QSAR-based solubility model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 18(19), 7078-7084 (2010-09-03) Design and development of novel lipid based gastroretentive delivery system: response surface analysis, in-vivo imaging and pharmacokinetic study.Aly Ahmed Abdelbary et al.Drug delivery, 22(1), 37-49 (2013-12-20) Polycaprolactone thin-film drug delivery systems: empirical and predictive models for device designSchlesinger E, et al. Materials Science and Engineering, C, 57, 232-239 (2015) Famotidine augmentation in schizophrenia: hope or hype?Chittaranjan Andrade The Journal of clinical psychiatry, 74(9), e855-e858 (2013-10-11) [Risk factors of gastroduodenal bleeding in patients with severe burns].D O Vagner et al.Vestnik khirurgii imeni I. I. Grekova, 172(1), 55-59 (2013-07-03) HZT-501 (DUEXIS(®); ibuprofen 800 mg/famotidine 26.6 mg) gastrointestinal protection in the treatment of the signs and symptoms of rheumatoid arthritis and osteoarthritis.Michael Schiff et al.Expert review of gastroenterology & hepatology, 6(1), 25-35 (2011-12-14) Selection of generic preparations of famotidine orally disintegrating tablets for use in unit-dose packages.N Yamazaki et al.Drug discoveries & therapeutics, 6(5), 263-268 (2012-12-12) Impact of a clinical pharmacist stress ulcer prophylaxis management program on inappropriate use in hospitalized patients.Mitchell S Buckley et al.The American journal of medicine, 128(8), 905-913 (2015-03-31) Physico-chemical comparison of famotidine tablets prepared via dry granulation and direct compression techniques.Abdul Baseer et al.Pakistan journal of pharmaceutical sciences, 26(3), 439-443 (2013-04-30) Impact of proton pump inhibitors or famotidine on the antiplatelet actions during dual-antiplatelet therapy in Japanese patients.Yoshiki Nagata et al.Cardiovascular intervention and therapeutics, 28(1), 22-29 (2012-08-14) "Development and evaluation of sodium alginate-polyacrylamide graft-co-polymer-based stomach targeted hydrogels of famotidine".Rahul Tripathi et al.AAPS PharmSciTech, 13(4), 1091-1102 (2012-09-01) Prediction of pH dependent absorption using in vitro, in silico, and in vivo rat models: Early liability assessment during lead optimization.Ajay Saxena et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 76, 173-180 (2015-05-12) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Multiple cerebral infarctions related to famotidine-induced eosinophilia.Chi-Shun Wu et al.Journal of neurology, 259(10), 2229-2231 (2012-05-16) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.S Takayama et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(1), 41-52 (2012-03-31) Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.Liang Hong et al.Scientific reports, 5, 14077-14077 (2015-09-15) Famotidine in gastroesophageal reflux disease (GERD).I C Wesdorp Hepato-gastroenterology, 39 Suppl 1, 24-26 (1992-02-01) Tablets compressed with gastric floating pellets coated with acrylic resin for gastro retention and sustained release of famotidine: in-vitro and in-vivo study.Xiaole Qi et al.The Journal of pharmacy and pharmacology, 67(4), 493-500 (2014-12-17) Prediction of drug intestinal absorption by new linear and non-linear QSPR.Alan Talevi et al.European journal of medicinal chemistry, 46(1), 218-228 (2010-11-30) Effects of famotidine or an antacid preparation on the pharmacokinetics of nilotinib in healthy volunteers.Ophelia Q P Yin et al.Cancer chemotherapy and pharmacology, 71(1), 219-226 (2012-10-17) Impact of active ingredients on the swelling properties of orally disintegrating tablets prepared by microwave treatment.Syusuke Sano et al.International journal of pharmaceutics, 468(1-2), 234-242 (2014-04-09) Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.Koji Takeuchi et al.Journal of gastroenterology and hepatology, 29 Suppl 4, 37-46 (2014-12-19) Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection.Toshihiko Tomita et al.Journal of gastroenterology and hepatology, 27(9), 1441-1446 (2012-04-14) Reduction in radiation-induced lymphocytopenia by famotidine in patients undergoing radiotherapy for prostate cancer.Abolfazl Razzaghdoust et al.The Prostate, 74(1), 41-47 (2013-09-11) [Famotidine--a new histamine H2 receptor blockader].P Ia Grigor'ev et al.Klinicheskaia meditsina, 69(4), 23-28 (1991-04-01) Possible involvement of radical intermediates in the inhibition of cysteine proteases by allenyl esters and amides.Yoshio Takeuchi et al.Bioorganic & medicinal chemistry letters, 18(23), 6202-6205 (2008-10-28) Disruption of histamine H2 receptor slows heart failure progression through reducing myocardial apoptosis and fibrosis.Zhi Zeng et al.Clinical science (London, England : 1979), 127(7), 435-448 (2014-03-25) Gastric acid inhibitors may prevent/heal oxyntic lesions by reducing blood demand.Helge Lyder Waldum et al.Gut, 62(1), 184-184 (2012-07-07) Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).Imre Laszlo Szabó et al.Current pharmaceutical design, 19(1), 84-89 (2012-09-06) The Japanese toxicogenomics project: application of toxicogenomics.Takeki Uehara et al.Molecular nutrition & food research, 54(2), 218-227 (2009-12-31) Electrospun formulations containing crystalline active pharmaceutical ingredients.Blair Kathryn Brettmann et al.Pharmaceutical research, 30(1), 238-246 (2012-08-28) Role of the thalamic submedius nucleus histamine H1 and H 2 and opioid receptors in modulation of formalin-induced orofacial pain in rats.Amir Erfanparast et al.Naunyn-Schmiedeberg's archives of pharmacology, 388(10), 1089-1096 (2015-06-17) Design and optimization of a chronotherapeutic dosage form for treatment of nocturnal acid breakthrough.Vaibhav Agarwal et al.Current drug delivery, 9(6), 608-616 (2012-09-01) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.R Scott Obach et al.Drug metabolism and disposition: the biological fate of chemicals, 36(7), 1385-1405 (2008-04-23) Famotidine: an update review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseaseHealther DL, et al. Drugs, 38(3), 551-590 (2015) Famotidine suppresses osteogenic differentiation of tendon cells in vitro and pathological calcification of tendon in vivo.Kenichi Yamamoto et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 30(12), 1958-1962 (2012-05-18) Slow-release of famotidine from tablets consisting of chitosan/sulfobutyl ether β-cyclodextrin composites.Makoto Anraku et al.International journal of pharmaceutics, 487(1-2), 142-147 (2015-04-18) The [3H] dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+] oDiaz GJ, et al. Journal of Pharmacological and Toxicological Methods, 50(3), 187-199 (2004) Clinical pharmacology of famotidine: a summary.A N Chremos Journal of clinical gastroenterology, 9 Suppl 2, 7-12 (1987-01-01) Taste-masking effect of physical and organoleptic methods on peppermint-scented orally disintegrating tablet of famotidine based on suspension spray-coating method.Takeshi Sugiura et al.Chemical & pharmaceutical bulletin, 60(3), 315-319 (2012-03-03) Famotidine in the management of schizophrenia.M C Martinez The Annals of pharmacotherapy, 33(6), 742-747 (1999-07-20) The place of famotidine in anti-ulcer therapy.S G Mann Alimentary pharmacology & therapeutics, 1 Suppl 1, 504S-509S (1987-01-01) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?Alex Avdeef et al.Journal of medicinal chemistry, 53(9), 3566-3584 (2010-04-09) Surface-Deacetylated Chitin Nano-Fiber/Hyaluronic Acid Composites as Potential Antioxidative Compounds for Use in Extended-Release Matrix Tablets.Makoto Anraku et al.International journal of molecular sciences, 16(10), 24707-24717 (2015-10-27) Outpatient intravenous interleukin-2 with famotidine has activity in metastatic melanoma.Walter D Y Quan et al.Cancer biotherapy & radiopharmaceuticals, 27(7), 442-445 (2012-06-27) In vitro effects of famotidine and ranitidine on lower esophageal sphincter tone in rats.Mahmut Özer et al.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 23(5), 438-443 (2012-11-20) Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.Xiaofan Sui et al.European journal of medicinal chemistry, 44(11), 4455-4460 (2009-07-10) Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.Mariusz J Świąder et al.Pharmacological reports : PR, 66(3), 485-491 (2014-06-07) Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugsTaha AS, et al. The New England Journal of Medicine, 334(22), 1435-1439 (1996) Clinical pharmacokinetics of famotidine.H Echizen et al.Clinical pharmacokinetics, 21(3), 178-194 (1991-09-01) Histamine H2-receptor antagonists for urticaria.Zbys Fedorowicz et al.The Cochrane database of systematic reviews, 3(3), CD008596-CD008596 (2012-03-16) Effect of histamine H2-receptor antagonist on the phosphorus-binding abilities of calcium carbonate and calcium lactate in hemodialysis patients.N Takahashi et al.Journal of the American Society of Nephrology : JASN, 10(5), 1090-1094 (1999-05-08) Pharmacokinetics and pharmacodynamics of famotidine in paediatric patients.L P James et al.Clinical pharmacokinetics, 31(2), 103-110 (1996-08-01) FDA-approved drug labeling for the study of drug-induced liver injury.Minjun Chen et al.Drug discovery today, 16(15-16), 697-703 (2011-06-01) Motilin Stimulates Gastric Acid Secretion in Coordination with Ghrelin in Suncus murinus.Chayon Goswami et al.PloS one, 10(6), e0131554-e0131554 (2015-06-27) Nursing care of patients receiving high-dose, continuous-infusion interleukin-2 with pulse dose and famotidine.Charley Cowan Tyre et al.Clinical journal of oncology nursing, 11(4), 513-519 (2007-08-29) Occupational allergic contact dermatitis from intermediate products in famotidine synthesis.D Guimaraens et al.Contact dermatitis, 31(4), 259-260 (1994-10-01) [Famotidine in the treatment of gastroduodenal ulcer].G Lengyel et al.Orvosi hetilap, 135(42), 2299-2304 (1994-10-16) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria.Daisuke Fujisawa et al.The Journal of allergy and clinical immunology, 134(3), 622-633 (2014-06-24) Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations.Asami Ono et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 64, 37-43 (2014-08-26) The tolerability and safety profile of famotidine.C W Howden et al.Clinical therapeutics, 18(1), 36-54 (1996-01-01)
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