Melting point	80-83 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
Oakwood	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

A Graphene-Based Glycan Biosensor for Electrochemical Label-Free Detection of a Tumor-Associated Antibody.Filip Kveton et al.Sensors (Basel, Switzerland), 19(24) (2019-12-11) Mannosylated T/Tn with Freund's adjuvant induces cellular immunity.Hye-Youn Son et al.International journal of immunopathology and pharmacology, 31, 394632017742504-394632017742504 (2017-12-19) Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer.Lenneke A M Cornelissen et al.Frontiers in oncology, 10, 1622-1622 (2020-10-06) Disruption of Core 1-mediated O-glycosylation oppositely regulates CD44 expression in human colon cancer cells and tumor-derived exosomes.Tianbo Gao et al.Biochemical and biophysical research communications, 521(2), 514-520 (2019-11-05) Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.Zhe Liu et al.Journal of cellular and molecular medicine, 23(3), 2083-2092 (2019-01-15) Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice.K Bergstrom et al.Mucosal immunology, 10(1), 91-103 (2016-05-05) Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.Kai Song et al.The Journal of biological chemistry, 290(33), 20159-20166 (2015-07-01) Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin.Sophie A Dusoswa et al.Proceedings of the National Academy of Sciences of the United States of America, 117(7), 3693-3703 (2020-02-06) CD44-Associated Tn Antigen as a New Biomarker of Tumor Cells with Aberrant Glycosylation.M L Shuvalova et al.Biochemistry. Biokhimiia, 85(9), 1064-1081 (2020-10-15) Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours.Sofia Cotton et al.Molecular oncology, 11(8), 895-912 (2017-02-06) Specific identification of glycoproteins bearing the Tn antigen in human cellsZheng J, et al. Angewandte Chemie (International Edition in English), 129(25), 7213-7217 (2017) Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies.Yasuyuki Matsumoto et al.Glycobiology, 30(5), 282-300 (2019-11-20) Glycan-directed CAR-T cells.Catharina Steentoft et al.Glycobiology, 28(9), 656-669 (2018-01-26) The Tn antigen?structural simplicity and biological complexityJu T, et al. Angewandte Chemie (International Edition in English), 50(8), 1770-1791 (2011) Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activationLiu Z, et al. Journal of Cellular and Molecular Medicine (2019) Oncogenic BRAFV600E drives expression of MGL ligands in the colorectal cancer cell line HT29 through N-acetylgalactosamine-transferase 3.Neha M Sahasrabudhe et al.Biological chemistry, 399(7), 649-659 (2018-06-13) Cosmc-dependent mucin-type O-linked glycosylation is essential for podocyte function.Brian R Stotter et al.American journal of physiology. Renal physiology, 318(2), F518-F530 (2020-01-07) T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition.Xichen Dong et al.BioMed research international, 2018, 9532389-9532389 (2018-07-24)

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