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N-(2-Phenylethyl)-4-hydroxypiperidine | CAS:3518-76-1
N-(2-Phenylethyl)-4-hydroxypiperidine
  • Name:N-(2-Phenylethyl)-4-hydroxypiperidine
  • CAS:3518-76-1
  • Synonyms:1-Phenethyl-4-piperidinol
  • Molecular Formula:C13H19NO
  • Molecular Weight:205.30
  • EINESC:222-527-7

Description

Properties

Melting point 95.5-98.5 ºC**
Boiling point 341.9±22.0 ºC (760 Tor
Flash point 123.8±16.5 ºC, 计算值*
Density 1.064±0.06 g/cm3 (20 º

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SDS

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Articles
Peer-Reviewed Papers
The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.Lei Chen et al.PloS one, 10(6), e0128696-e0128696 (2015-06-06) Chemotherapy in low-grade gliomas.Aurélien Viaccoz et al.Current opinion in oncology, 24(6), 694-701 (2012-08-24) Long-term survival in a dog with anaplastic oligodendroglioma treated with radiation therapy and CCNU.Daisuke Hasegawa et al.The Journal of veterinary medical science, 74(11), 1517-1521 (2012-07-13) Chemotherapy and radiotherapy combination extends survival for patients with oligodendroglial tumors.Carrie Printz Cancer, 118(18), 4368-4368 (2012-09-07) Autologous noncryopreserved hematopoietic stem cell transplant with CEAM as a modified conditioning regimen in patients with Hodgkin lymphoma: a single-center experience with a new protocol.Mani Ramzi et al.Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 10(2), 163-167 (2012-03-22) Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802.Edward G Shaw et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(25), 3065-3070 (2012-08-02) [Combined effect of gemcitabine and lomustine in mice with intracranial transplanted lymphosarcoma LIO-1].A N Stukov et al.Voprosy onkologii, 58(3), 394-397 (2012-08-15) High-dose etoposide in allogeneic stem cell transplantation.Oystein Bruserud et al.Cancer chemotherapy and pharmacology, 70(6), 765-782 (2012-10-12) Treatment of advanced neuroendocrine tumours using combination chemotherapy with lomustine and 5-fluorouracil.G A Kaltsas et al.Clinical endocrinology, 57(2), 169-183 (2002-08-03) Low apparent risk of CCNU (lomustine)-associated clinical hepatotoxicity in cats.Margaret L Musser et al.Journal of feline medicine and surgery, 14(12), 871-875 (2012-07-10) Phase II clinical evaluation of lomustine chemotherapy for feline vaccine-associated sarcoma.C F Saba et al.Veterinary and comparative oncology, 10(4), 283-291 (2012-01-13) Modified BEAM conditioning regimen in patients with Hodgkin and non-Hodgkin lymphomas.Abrahão Elias Hallack Neto et al.Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 10(6), 622-622 (2012-12-12) Bevacizumab alone at 5 mg/kg in an every-3-week schedule for patients with recurrent glioblastomas: a single center experience.Gentian Kaloshi et al.Tumori, 99(5), 601-603 (2013-12-24) Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma.Tracy T Batchelor et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(26), 3212-3218 (2013-08-14) [Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].Elodie Vauleon et al.Bulletin du cancer, 99(2), 121-126 (2012-01-20) Expression of O(6)-methylguanine-DNA methyltransferase causes lomustine resistance in canine lymphoma cells.Satoshi Kambayashi et al.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 79(3), 201-209 (2015-07-02) [Brain metastasis in breast cancer].L I Korytova et al.Voprosy onkologii, 57(5), 672-674 (2012-01-14) Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402.Gregory Cairncross et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(3), 337-343 (2012-10-17) New clinical, pathological and molecular prognostic models and calculators in patients with locally diagnosed anaplastic oligodendroglioma or oligoastrocytoma. A prognostic factor analysis of European Organisation for Research and Treatment of Cancer Brain Tumour Group Study 26951.Thierry Gorlia et al.European journal of cancer (Oxford, England : 1990), 49(16), 3477-3485 (2013-07-31) Evaluation of lomustine as a rescue agent for cats with resistant lymphoma.Autumn L Dutelle et al.Journal of feline medicine and surgery, 14(10), 694-700 (2012-05-12) Integrated phase II/III clinical trials in oncology: a case study.Meihua Wang et al.Clinical trials (London, England), 9(6), 741-747 (2012-11-28) Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group.Joann L Ater et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(21), 2641-2647 (2012-06-06) Cervicothoracic syringohydromyelia associated with a prosencephalic mass in a dog.D Szabo et al.The Journal of small animal practice, 53(10), 613-617 (2012-09-28) Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.Martin J van den Bent et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(3), 344-350 (2012-10-17) Chemotherapy dose-intensity and survival for childhood medulloblastoma.R L Smith et al.Anticancer research, 32(9), 3885-3892 (2012-09-21) Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study.Carsten Friedrich et al.European journal of cancer (Oxford, England : 1990), 49(4), 893-903 (2012-11-28) The nitrosoureas: carmustine (BCNU) and lomustine (CCNU).R B Weiss et al.Cancer treatment reviews, 9(4), 313-330 (1982-12-01) EORTC 26083 phase I/II trial of dasatinib in combination with CCNU in patients with recurrent glioblastoma.Enrico Franceschi et al.Neuro-oncology, 14(12), 1503-1510 (2012-10-24) Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951.Lale Erdem-Eraslan et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(3), 328-336 (2012-12-28) Preliminary study of lomustine in the treatment of intracranial masses in dogs following localization by imaging techniques.L M Fulton et al.Seminars in veterinary medicine and surgery (small animal), 5(4), 241-245 (1990-11-01) Survival and secondary tumors in children with medulloblastoma receiving radiotherapy and adjuvant chemotherapy: results of Children's Oncology Group trial A9961.Roger J Packer et al.Neuro-oncology, 15(1), 97-103 (2012-10-27) Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.Moritz Stuplich et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(21), e180-e183 (2012-06-13) Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: an analysis of ACCENT adjuvant trials.Greg Yothers et al.Journal of the National Cancer Institute, 103(20), 1498-1506 (2011-10-15) The role of an all-oral chemotherapy containing lomustine (CCNU) in advanced,fs progressive Hodgkin lymphoma: a patient-friendly palliative option which can result in long-term disease control.S J Proctor et al.Annals of oncology : official journal of the European Society for Medical Oncology, 21(2), 426-428 (2009-11-11)
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