Melting point	217 ºC (dec.)

Symbol(GHS)	T
Hazard Codes	R23/24/25;R36/37/38
SDS/MSDS	S26;S36/37/39;S45

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
Acros-Organics	View & Download

Synthetic Route

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Peer-Reviewed Papers

Oral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology.Chinna Reddy Palem et al.Pharmaceutical development and technology, 18(1), 186-195 (2012-08-14) Question 2. How effective is domperidone at reducing symptoms of gastro-oesophageal reflux in infants?Bryonnie Scott Archives of disease in childhood, 97(8), 752-755 (2012-08-04) Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish.Tianna Zhao et al.PloS one, 7(11), e48911-e48911 (2012-11-08) [Efficacy controlled observation on acupuncture and western medicine for gastrointestinal dysmotility in liver cirrhosis].Jing-Jing Deng et al.Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 33(5), 389-393 (2013-07-28) Domperidone. Discovering new choices for lactating mothers.Amanda Henderson AWHONN lifelines, 7(1), 54-60 (2003-04-04) The metoclopramide black box warning for tardive dyskinesia: effect on clinical practice, adverse event reporting, and prescription drug lawsuits.Eli D Ehrenpreis et al.The American journal of gastroenterology, 108(6), 866-872 (2013-06-06) Domperidone and long QT syndrome.Marco Rossi et al.Current drug safety, 5(3), 257-262 (2010-04-17) Evidence for the involvement of dopamine in stress-induced suppression of reproduction in the cichlid fish Oreochromis mossambicus.A Chabbi et al.Journal of neuroendocrinology, 27(5), 343-356 (2015-02-26) Clinical challenge. Esophageal hiatal hernia.Maria Cristina Ferrarini Nunes Soares Hage et al.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 45(4), 999-1001 (2015-01-31) Making a case for domperidone in the treatment of gastrointestinal motility disorders.Naveed Ahmad et al.Current opinion in pharmacology, 6(6), 571-576 (2006-09-26) Effects of dopamine 2 receptor antagonist on sex steroid levels, oocyte maturation and spawning performances in Waigieu seaperch (Psammoperca waigiensis).Hung Quoc Pham et al.Fish physiology and biochemistry, 39(2), 403-411 (2012-08-23) Domperidone.S Cherian et al.Indian pediatrics, 26(9), 932-935 (1989-09-01) Quality and quantity of smelt (Osmerus eperlanus L.) sperm in relation to time after hormonal stimulation.Radosław K Kowalski et al.Reproductive biology, 12(2), 231-246 (2012-08-02) Domperidone: a peripherally acting dopamine2-receptor antagonist.J A Barone The Annals of pharmacotherapy, 33(4), 429-440 (1999-05-20) Domperidone: ventricular arrhythmia and sudden death (continued). Prescrire international, 21(129), 183-183 (2012-08-03) The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis.Pieter Janssen et al.The American journal of gastroenterology, 108(9), 1382-1391 (2013-09-06) Should domperidone be used for the treatment of gastro-oesophageal reflux in children? Systematic review of randomized controlled trials in children aged 1 month to 11 years old.D S Pritchard et al.British journal of clinical pharmacology, 59(6), 725-729 (2005-06-14) Domperidone, a new dopamine antagonist.M C Champion et al.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 135(5), 457-461 (1986-09-01) Efficacy of domperidone gel in an induced model of fescue toxicosis in periparturient mares.D L Cross et al.Theriogenology, 78(6), 1361-1370 (2012-08-18) Efficacy of amitriptyline, pizotifen and propranolol in the prevention of migraine.A Israil et al.Mymensingh medical journal : MMJ, 22(1), 93-100 (2013-02-19) Convolution and validation of in vitro-in vivo correlation of water-insoluble sustained-release drug (domperidone) by first-order pharmacokinetic one-compartmental model fitting equation.Anirbandeep Bose et al.European journal of drug metabolism and pharmacokinetics, 38(3), 191-200 (2012-12-25) Aggregation behavior of amphiphilic p(HPMA)-co-p(LMA) copolymers studied by FCS and EPR spectroscopy.Mirjam Hemmelmann et al.Biomacromolecules, 13(12), 4065-4074 (2012-11-20) Electrical bioimpedance gastric motility measurement based on an electrical-mechanical composite mechanism.Shu Zhao et al.World journal of gastroenterology, 18(25), 3282-3287 (2012-07-12) Effect of piperine, a major component of black pepper, on the pharmacokinetics of domperidone in rats.M S Alhumayyd et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 65(6), 785-789 (2015-01-03) Enhancing breast milk production with Domperidone in mothers of preterm neonates (EMPOWER trial).Elizabeth V Asztalos et al.BMC pregnancy and childbirth, 12, 87-87 (2012-09-01) Use of metoclopramide, domperidone, and cisapride in the management of diabetic gastroparesis.C K Brown et al.Clinical pharmacy, 9(5), 357-365 (1990-05-01) Domperidone-induced acute dystonia and polycystic ovary syndrome.U Bonuccelli et al.Movement disorders : official journal of the Movement Disorder Society, 6(1), 79-81 (1991-01-01) Serum deprivation confers the MDA-MB-231 breast cancer line with an EGFR/JAK3/PLD2 system that maximizes cancer cell invasion.Qing Ye et al.Journal of molecular biology, 425(4), 755-766 (2012-12-15) Dopamine inhibits reproduction in female zebrafish (Danio rerio) via three pituitary D2 receptor subtypes.Romain Fontaine et al.Endocrinology, 154(2), 807-818 (2013-01-09) A systematic review of the efficacy of domperidone for the treatment of diabetic gastroparesis.Aravind Sugumar et al.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 6(7), 726-733 (2008-06-06) Domperidone and sudden cardiac death: How much longer should we wait?Veronique Michaud et al.Journal of cardiovascular pharmacology, 61(3), 215-217 (2013-01-19) Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier.Mike De Vrieze et al.Analytical and bioanalytical chemistry, 406(25), 6179-6188 (2014-08-16) Health Canada advisory on domperidone should I avoid prescribing domperidone to women to increase milk production [corrected]?Pina Bozzo et al.Canadian family physician Medecin de famille canadien, 58(9), 952-953 (2012-09-14) Domperidone: review of pharmacology and clinical applications in gastroenterology.Savio C Reddymasu et al.The American journal of gastroenterology, 102(9), 2036-2045 (2007-05-10) Simultaneous determination of Cinnarizine and Domperidone by area under curve and dual wavelength spectrophotometric methods.Maha M Abdelrahman Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 113, 291-296 (2013-06-06) Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report.David Stegner et al.Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2212-2217 (2013-07-23) Domperidone. A review of its pharmacological activity, pharmacokinetics and therapeutic efficacy in the symptomatic treatment of chronic dyspepsia and as an antiemetic.R N Brogden et al.Drugs, 24(5), 360-400 (1982-11-01) Gastroesophageal reflux: natural evolution, diagnostic approach and treatment.Badriul Hegar et al.The Turkish journal of pediatrics, 55(1), 1-7 (2013-05-23) Domperidone.M C Champion General pharmacology, 19(4), 499-505 (1988-01-01) Domperidone interacts with pioglitazone but not with ondansetron via common CYP metabolism in vitro.Amir S Youssef et al.Xenobiotica; the fate of foreign compounds in biological systems, 44(9), 792-803 (2014-03-20) Preparation and characterization of domperidone solid dispersions.Ebtessam Ahmed Essa et al.Pakistan journal of pharmaceutical sciences, 25(4), 783-791 (2012-09-27) Domperidone as a tool to assess the role of dopamine within carotid body chemoreception.P Zapata et al.Advances in experimental medicine and biology, 410, 291-297 (1996-01-01) [Domperidone, diclofenac: the time has come for drug alerts].Jean-Yves Nau Revue medicale suisse, 9(382), 852-853 (2013-05-15) Domperidone. A review of its use in diabetic gastropathy.A Prakash et al.Drugs, 56(3), 429-445 (1998-10-20) Development and validation of UPLC-MS/MS method for determination of domperidone in human plasma and its pharmacokinetic application.Xintao Wang et al.Biomedical chromatography : BMC, 27(3), 371-376 (2012-08-16) Restless legs syndrome outside the blood-brain barrier--exacerbation by domperidone in Parkinson's disease.S Rios Romenets et al.Parkinsonism & related disorders, 19(1), 92-94 (2012-08-28) A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models.Lawrence O Olala et al.Molecular and cellular endocrinology, 366(1), 31-37 (2012-11-28) [Domperidone and the risk of sudden cardiac death].Sonja E van Roeden et al.Nederlands tijdschrift voor geneeskunde, 157(45), A6770-A6770 (2013-11-07) Evaluation and comparison of different brands of domperidone tablets available in Karachi, Pakistan.Muhammad Qamar Khan et al.Pakistan journal of pharmaceutical sciences, 27(4), 935-938 (2014-07-13) Domperidone and Parkinson's disease.J D Parkes Clinical neuropharmacology, 9(6), 517-532 (1986-01-01) Domperidone: limited benefits with significant risk for sudden cardiac death.Luc M Hondeghem Journal of cardiovascular pharmacology, 61(3), 218-225 (2012-11-29) Gum Ghatti--a pharmaceutical excipient: development, evaluation and optimization of sustained release mucoadhesive matrix tablets of domperidone.Gurpreetarora et al.Acta poloniae pharmaceutica, 69(4), 725-737 (2012-08-11)

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