Melting point	75 ºC (ligroine )**
Density	1.136±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

Rab5 GTPases are required for optimal TORC2 function.Melissa N Locke et al.The Journal of cell biology, 218(3), 961-976 (2018-12-24) Age dependence of oval cell responses and bile duct carcinomas in male fischer 344 rats fed a cyclic choline-deficient, ethionine-supplemented diet.Ian Guest et al.Hepatology (Baltimore, Md.), 52(5), 1750-1757 (2010-09-16) Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice.Agnès Fourcot et al.American journal of physiology. Gastrointestinal and liver physiology, 300(6), G1043-G1053 (2011-02-26) An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial.Helen Hurst et al.Reproductive toxicology (Elmsford, N.Y.), 28(4), 503-510 (2009-08-04) Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury.Soona Shin et al.Gastroenterology, 148(1), 192-202 (2014-10-07) Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.Michael Römer et al.PloS one, 9(5), e97640-e97640 (2014-05-17) Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.Aymeric Goyer et al.Plant & cell physiology, 48(2), 232-242 (2006-12-16) Identification and characterization of genes related to the production of organic acids in yeast.Satoshi Yoshida et al.Journal of bioscience and bioengineering, 113(5), 556-561 (2012-01-27) Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury.Noémi Van Hul et al.The American journal of pathology, 179(4), 1839-1850 (2011-08-23) Proliferation, differentiation and apoptosis of choline deficient ethionine supplemented diet-rat oval cells under the influence of 2-methoxyestradiol.M Wojcik et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(6), 669-676 (2013-02-08) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Adaptive remodeling of the biliary architecture underlies liver homeostasis.Kota Kaneko et al.Hepatology (Baltimore, Md.), 61(6), 2056-2066 (2015-01-13) Ethionine-induced ATP depletion represses mTOR signaling in the absence of increases in AMP-activated protein kinase activity in the rat liver.Fumiaki Yoshizawa et al.Bioscience, biotechnology, and biochemistry, 73(9), 1984-1988 (2009-09-08) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Induction of methionine sulfoxide reductase activity by pergolide, pergolide sulfoxide, and S-adenosyl-methionine in neuronal cells.Jade M Franklin et al.Neuroscience letters, 533, 86-89 (2012-11-28) The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.Jennifer A Sanders et al.Experimental and molecular pathology, 93(1), 40-49 (2012-04-25) FERONIA receptor kinase interacts with S-adenosylmethionine synthetase and suppresses S-adenosylmethionine production and ethylene biosynthesis in Arabidopsis.Dandan Mao et al.Plant, cell & environment, 38(12), 2566-2574 (2015-05-20) Effects of acute ethionine injection on plasma ghrelin and obestatin levels in trained male rats.Abbass Ghanbari-Niaki et al.Metabolism: clinical and experimental, 59(7), 982-987 (2010-01-05) Bmi1 is required for regeneration of the exocrine pancreas in mice.Akihisa Fukuda et al.Gastroenterology, 143(3), 821-831 (2012-05-23) An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated.Percy Ho et al.BMC molecular biology, 8, 87-87 (2007-10-05) Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.Dennis J Pelletier et al.Journal of chemical information and modeling, 47(3), 1196-1205 (2007-04-13) Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet.Shingo Akita et al.Biochemical and biophysical research communications, 420(4), 743-749 (2012-04-03) Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.Quanyan Liu et al.Hepatology research : the official journal of the Japan Society of Hepatology, 37(5), 376-388 (2007-04-20) Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells.Janina E E Tirnitz-Parker et al.Hepatology (Baltimore, Md.), 52(1), 291-302 (2010-06-26) Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Luke Boulter et al.Nature medicine, 18(4), 572-579 (2012-03-06) The Japanese toxicogenomics project: application of toxicogenomics.Takeki Uehara et al.Molecular nutrition & food research, 54(2), 218-227 (2009-12-31) Impaired liver glucose production in a murine model of steatosis and endotoxemia: protection by inducible nitric oxide synthase.Oren Tirosh et al.Antioxidants & redox signaling, 13(1), 13-26 (2009-12-03) Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response.Yiannis N Kallis et al.Gut, 60(4), 525-533 (2010-11-26) L-leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst.Makoto Hibi et al.Applied microbiology and biotechnology, 97(6), 2467-2472 (2012-05-16) Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.Kathleen H Mortell et al.Bioorganic & medicinal chemistry letters, 16(5), 1138-1141 (2005-12-29) Opposite effects of GPR120 and GPR40 on cell motile activity induced by ethionine in liver epithelial cells.Shuhei Ishii et al.Biochemical and biophysical research communications, 456(1), 135-138 (2014-12-03) Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos.Shuntaro Ikeda et al.The Journal of reproduction and development, 58(1), 91-97 (2011-11-05) Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet.Joanne N Tonkin et al.Stem cell research, 1(3), 195-204 (2009-04-23) The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein.Angel L Pey et al.Biochimica et biophysica acta, 1844(9), 1453-1462 (2014-05-02) Small-molecule inhibitors of the protein methyltransferase SET7/9 identified in a high-throughput screen.Nicola-Jane Francis et al.Journal of biomolecular screening, 17(8), 1102-1109 (2012-07-10) Automated annotation and quantification of metabolites in 1H NMR data of biological origin.Erik Alm et al.Analytical and bioanalytical chemistry, 403(2), 443-455 (2012-03-01) Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice.Michal Aharoni-Simon et al.Laboratory investigation; a journal of technical methods and pathology, 91(7), 1018-1028 (2011-04-06) Imprinting: RNA expression for homocysteine recycling in the human oocyte.Moncef Benkhalifa et al.Fertility and sterility, 93(5), 1585-1590 (2009-04-14) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Microbial L-methioninase: production, molecular characterization, and therapeutic applications.Ashraf S El-Sayed Applied microbiology and biotechnology, 86(2), 445-467 (2010-02-11) Time-resolved biomarker discovery in 1H-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis.Erik Alm et al.Analytical and bioanalytical chemistry, 396(5), 1681-1689 (2010-01-21) Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet.Satoshi Ida et al.Experimental animals, 59(4), 421-429 (2010-07-28)

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