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4-Chloro-2-picoline | CAS:3678-63-5
4-Chloro-2-picoline
  • Name:4-Chloro-2-picoline
  • CAS:3678-63-5
  • Synonyms:4-Chloro-2-methylpyridine
  • Molecular Formula:C6H6ClN
  • Molecular Weight:127.57
  • EINESC:

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Properties

Density 1.156

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Peer-Reviewed Papers
Establishment of a Primary Screening Assay for the DHX9 Helicase.Regina Cencic et al.Combinatorial chemistry & high throughput screening, 18(9), 855-861 (2015-10-20) The quorum sensing regulator CinR hierarchically regulates two other quorum sensing pathways in ligand-dependent and -independent fashions in Rhizobium etli.Huiming Zheng et al.Journal of bacteriology, 197(9), 1573-1581 (2015-02-19) Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein.Shuichi Sekine et al.Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30) A new member of the DMATS superfamily from Aspergillus niger catalyzes prenylations of both tyrosine and tryptophan derivatives.Aili Fan et al.Applied microbiology and biotechnology, 98(24), 10119-10129 (2014-06-28) Heterofunctional Magnetic Metal-Chelate-Epoxy Supports for the Purification and Covalent Immobilization of Benzoylformate Decarboxylase From Pseudomonas Putida and Its Carboligation Reactivity.Servet Tural et al.Chirality, 27(9), 635-642 (2015-07-07) Subtype-specific analysis of the K65R substitution in HIV-1 that confers hypersusceptibility to a novel nucleotide-competing reverse transcriptase inhibitor.Hong-Tao Xu et al.Antimicrobial agents and chemotherapy, 59(6), 3189-3196 (2015-03-18) Preparation of monoPEGylated Cyanovirin-N's derivative and its anti-influenza A virus bioactivity in vitro and in vivo.Chongchao Wu et al.Journal of biochemistry, 157(6), 539-548 (2015-02-26) PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis.Min-Sik Lee et al.Nature communications, 6, 7769-7769 (2015-07-18) In Salmonella enterica, the Gcn5-related acetyltransferase MddA (formerly YncA) acetylates methionine sulfoximine and methionine sulfone, blocking their toxic effects.Kristy L Hentchel et al.Journal of bacteriology, 197(2), 314-325 (2014-11-05) Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase.Claire L Price et al.Applied and environmental microbiology, 81(10), 3379-3386 (2015-03-10) TAT-mediated delivery of neuroglobin attenuates apoptosis induced by oxygen-glucose deprivation via the Jak2/Stat3 pathway in vitro.Yi Lin et al.Neurological research, 37(6), 531-538 (2014-07-16) Intersectin adaptor proteins are associated with actin-regulating protein WIP in invadopodia.Tetyana Gryaznova et al.Cellular signalling, 27(7), 1499-1508 (2015-03-24) GHSC70 is involved in the cellular entry of nervous necrosis virus.Jui-Shin Chang et al.Journal of virology, 89(1), 61-70 (2014-10-17) Characterization of an IL-12 p40/p35 Truncated Fusion Protein That can Inhibit the Action of IL-12.Denise Skrombolas et al.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 35(9), 690-697 (2015-05-06) Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.Ryuichi Miura et al.PLoS neglected tropical diseases, 9(7), e0003914-e0003914 (2015-07-15) Lipoprotein(a) determination in human serum using a nitrilotriacetic acid derivative immunosensing scaffold on disposable electrodes.Berta Esteban-Fernández de Ávila et al.Analytical and bioanalytical chemistry, 406(22), 5379-5387 (2014-06-24) Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent.Liron Nesiel-Nuttman et al.Oncotarget, 5(22), 11464-11478 (2014-11-27) Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.Tatsuhiro Igawa et al.FEBS letters, 589(6), 680-686 (2015-02-11) Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS.Fatemeh Momen-Heravi et al.Scientific reports, 5, 9991-9991 (2015-05-15) Molecular snapshots of the Pex1/6 AAA+ complex in action.Susanne Ciniawsky et al.Nature communications, 6, 7331-7331 (2015-06-13) Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1.Milo B Fasken et al.PLoS genetics, 11(3), e1005044-e1005044 (2015-03-17) Host erythrocyte environment influences the localization of exported protein 2, an essential component of the Plasmodium translocon.Elamaran Meibalan et al.Eukaryotic cell, 14(4), 371-384 (2015-02-11) Efficient generation of functional hepatocyte-like cells from menstrual blood-derived stem cells.Sayeh Khanjani et al.Journal of tissue engineering and regenerative medicine, 9(11), E124-E134 (2013-03-19) An evolved Mxe GyrA intein for enhanced production of fusion proteins.Carrie J Marshall et al.ACS chemical biology, 10(2), 527-538 (2014-11-11) Autographa californica multiple nucleopolyhedrovirus ORF11 is essential for budded-virus production and occlusion-derived-virus envelopment.Xue Ying Tao et al.Journal of virology, 89(1), 373-383 (2014-10-17) A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains.Silvia Wuertenberger et al.FEBS letters, 589(10), 1156-1163 (2015-03-31) The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice.Anne E Bausch et al.Learning & memory (Cold Spring Harbor, N.Y.), 22(7), 323-335 (2015-06-17) Insights into a type III cohesin-dockerin recognition interface from the cellulose-degrading bacterium Ruminococcus flavefaciens.Jonathan Y Weinstein et al.Journal of molecular recognition : JMR, 28(3), 148-154 (2015-02-03) Preparation and functional characterization of human vascular endothelial growth factor-melittin fusion protein with analysis of the antitumor activity in vitro and in vivo.Dingding Wang et al.International journal of oncology, 47(3), 1160-1168 (2015-07-15) Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal salts.Yijia Li et al.Antimicrobial agents and chemotherapy, 59(7), 4148-4156 (2015-05-06) The quorum sensing regulator CinR hierarchically regulates two other quorum sensing pathways in ligand-dependent and -independent fashions in Rhizobium etli.Huiming Zheng et al.Journal of bacteriology, 197(9), 1573-1581 (2015-02-19) Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase.Claire L Price et al.Applied and environmental microbiology, 81(10), 3379-3386 (2015-03-10) TAT-mediated delivery of neuroglobin attenuates apoptosis induced by oxygen-glucose deprivation via the Jak2/Stat3 pathway in vitro.Yi Lin et al.Neurological research, 37(6), 531-538 (2014-07-16) Intersectin adaptor proteins are associated with actin-regulating protein WIP in invadopodia.Tetyana Gryaznova et al.Cellular signalling, 27(7), 1499-1508 (2015-03-24) Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.Ryuichi Miura et al.PLoS neglected tropical diseases, 9(7), e0003914-e0003914 (2015-07-15) Lipoprotein(a) determination in human serum using a nitrilotriacetic acid derivative immunosensing scaffold on disposable electrodes.Berta Esteban-Fernández de Ávila et al.Analytical and bioanalytical chemistry, 406(22), 5379-5387 (2014-06-24) Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.Tatsuhiro Igawa et al.FEBS letters, 589(6), 680-686 (2015-02-11) Preparation of monoPEGylated Cyanovirin-N's derivative and its anti-influenza A virus bioactivity in vitro and in vivo.Chongchao Wu et al.Journal of biochemistry, 157(6), 539-548 (2015-02-26) Subtype-specific analysis of the K65R substitution in HIV-1 that confers hypersusceptibility to a novel nucleotide-competing reverse transcriptase inhibitor.Hong-Tao Xu et al.Antimicrobial agents and chemotherapy, 59(6), 3189-3196 (2015-03-18) Molecular snapshots of the Pex1/6 AAA+ complex in action.Susanne Ciniawsky et al.Nature communications, 6, 7331-7331 (2015-06-13) Replication of boid inclusion body disease-associated arenaviruses is temperature sensitive in both boid and mammalian cells.Jussi Hepojoki et al.Journal of virology, 89(2), 1119-1128 (2014-11-08) Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.Olof Idevall-Hagren et al.The EMBO journal, 34(17), 2291-2305 (2015-07-24) Study of the putative fusion regions of the preS domain of hepatitis B virus.Carmen L Delgado et al.Biochimica et biophysica acta, 1848(4), 895-906 (2015-01-03) Biodegradation of fenoxaprop-P-ethyl (FE) by Acinetobacter sp. strain DL-2 and cloning of FE hydrolase gene afeH.Weiliang Dong et al.Bioresource technology, 186, 114-121 (2015-03-31) Deleterious c-Cbl Exon Skipping Contributes to Human Glioma.Min Woo Seong et al.Neoplasia (New York, N.Y.), 17(6), 518-524 (2015-07-15) Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidase.Danielle B Steed et al.Antimicrobial agents and chemotherapy, 59(7), 3887-3898 (2015-04-22) A high-affinity fluorescence probe for copper(II) ions and its application in fluorescence lifetime correlation spectroscopy.Andreas Grüter et al.Analytical and bioanalytical chemistry, 411(15), 3229-3240 (2019-04-27) Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.Gary Male et al.Nature communications, 6, 7387-7387 (2015-06-11) Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis.Weixing Zhao et al.Nucleic acids research, 43(8), 4055-4066 (2015-03-31) Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters.Qin Zhao et al.Nature communications, 6, 7661-7661 (2015-07-23) Phosphoproteome Analysis Links Protein Phosphorylation to Cellular Remodeling and Metabolic Adaptation during Magnaporthe oryzae Appressorium Development.William L Franck et al.Journal of proteome research, 14(6), 2408-2424 (2015-05-01) Efficient generation of functional hepatocyte-like cells from menstrual blood-derived stem cells.Sayeh Khanjani et al.Journal of tissue engineering and regenerative medicine, 9(11), E124-E134 (2013-03-19) An adverse outcome pathway framework for neural tube and axial defects mediated by modulation of retinoic acid homeostasis.Elisa C M Tonk et al.Reproductive toxicology (Elmsford, N.Y.), 55, 104-113 (2014-12-03) The Plasmodium vivax rhoptry neck protein 5 is expressed in the apical pole of Plasmodium vivax VCG-1 strain schizonts and binds to human reticulocytes.Gabriela Arévalo-Pinzón et al.Malaria journal, 14, 106-106 (2015-04-19) Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.Helen J Whalley et al.Nature communications, 6, 7437-7437 (2015-06-17) Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations.Christian S Müller et al.Biochemistry, 54(3), 711-721 (2014-12-30) Directed evolution of Gloeobacter violaceus rhodopsin spectral properties.Martin K M Engqvist et al.Journal of molecular biology, 427(1), 205-220 (2014-07-01) TRIM28 and β-actin identified via nanobody-based reverse proteomics approach as possible human glioblastoma biomarkers.Ivana Jovčevska et al.PloS one, 9(11), e113688-e113688 (2014-11-25) CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism.Jayan Rammohan et al.Nucleic acids research, 43(6), 3272-3285 (2015-02-24) Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.Clara Brieke et al.Organic & biomolecular chemistry, 13(7), 2012-2021 (2014-12-17) Nucleotide-Induced Conformational Changes in Escherichia coli DnaA Protein Are Required for Bacterial ORC to Pre-RC Conversion at the Chromosomal Origin.Rahul Saxena et al.International journal of molecular sciences, 16(11), 27897-27911 (2015-11-28) Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense.Mario Waespy et al.PLoS neglected tropical diseases, 9(10), e0004120-e0004120 (2015-10-17) Membrane Topology and Biochemical Characterization of the Escherichia coli BacA Undecaprenyl-Pyrophosphate Phosphatase.Guillaume Manat et al.PloS one, 10(11), e0142870-e0142870 (2015-11-13) Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids.Yan Li et al.Biochimica et biophysica acta, 1848(12), 3150-3157 (2015-09-26) Computational design and experimental verification of a symmetric protein homodimer.Yun Mou et al.Proceedings of the National Academy of Sciences of the United States of America, 112(34), 10714-10719 (2015-08-14) Inhibition of aminoglycoside acetyltransferase resistance enzymes by metal salts.Yijia Li et al.Antimicrobial agents and chemotherapy, 59(7), 4148-4156 (2015-05-06) Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase.Meike Hüdig et al.Plant & cell physiology, 56(9), 1820-1830 (2015-07-24) Behavioral Deficits Are Accompanied by Immunological and Neurochemical Changes in a Mouse Model for Neuropsychiatric Lupus (NP-SLE).Yan Li et al.International journal of molecular sciences, 16(7), 15150-15171 (2015-07-08) GRPR-targeted Protein Contrast Agents for Molecular Imaging of Receptor Expression in Cancers by MRI.Fan Pu et al.Scientific reports, 5, 16214-16214 (2015-11-19) Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation.I K Herrmann et al.Nanoscale, 7(32), 13511-13520 (2015-07-24) Host erythrocyte environment influences the localization of exported protein 2, an essential component of the Plasmodium translocon.Elamaran Meibalan et al.Eukaryotic cell, 14(4), 371-384 (2015-02-11) Functional Characterization of the Receiver Domain for Phosphorelay Control in Hybrid Sensor Kinases.Emiko Kinoshita-Kikuta et al.PloS one, 10(7), e0132598-e0132598 (2015-07-08) A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains.Silvia Wuertenberger et al.FEBS letters, 589(10), 1156-1163 (2015-03-31) Truncation of domain V of the multidomain glucansucrase GTF180 of Lactobacillus reuteri 180 heavily impairs its polysaccharide-synthesizing ability.Xiangfeng Meng et al.Applied microbiology and biotechnology, 99(14), 5885-5894 (2015-01-15) The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice.Anne E Bausch et al.Learning & memory (Cold Spring Harbor, N.Y.), 22(7), 323-335 (2015-06-17) Insights into a type III cohesin-dockerin recognition interface from the cellulose-degrading bacterium Ruminococcus flavefaciens.Jonathan Y Weinstein et al.Journal of molecular recognition : JMR, 28(3), 148-154 (2015-02-03) Autographa californica multiple nucleopolyhedrovirus ORF11 is essential for budded-virus production and occlusion-derived-virus envelopment.Xue Ying Tao et al.Journal of virology, 89(1), 373-383 (2014-10-17) Preparation and functional characterization of human vascular endothelial growth factor-melittin fusion protein with analysis of the antitumor activity in vitro and in vivo.Dingding Wang et al.International journal of oncology, 47(3), 1160-1168 (2015-07-15) Beyond glycolysis: GAPDHs are multi-functional enzymes involved in regulation of ROS, autophagy, and plant immune responses.Elizabeth Henry et al.PLoS genetics, 11(4), e1005199-e1005199 (2015-04-29) Deinococcus radiodurans PriA is a Pseudohelicase.Matthew E Lopper et al.PloS one, 10(7), e0133419-e0133419 (2015-07-17) Wide expression of type I Na+-phosphate cotransporter 3 (NPT3/SLC17A2), a membrane 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Cell physiology, 309(2), C71-C80 (2015-05-15) An evolved Mxe GyrA intein for enhanced production of fusion proteins.Carrie J Marshall et al.ACS chemical biology, 10(2), 527-538 (2014-11-11) Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.Frederic F Depreux et al.Human molecular genetics, 24(15), 4284-4295 (2015-05-08) Citrem modulates internal nanostructure of glyceryl monooleate dispersions and bypasses complement activation: Towards development of safe tunable intravenous lipid nanocarriers.Peter P Wibroe et al.Nanomedicine : nanotechnology, biology, and medicine, 11(8), 1909-1914 (2015-09-09) Site-Directed Mutagenesis of a Hyperthermophilic Endoglucanase Cel12B from Thermotoga maritima Based on Rational Design.Jinfeng Zhang et al.PloS one, 10(7), e0133824-e0133824 (2015-07-29) Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells.Małgorzata Stec et al.Journal of translational medicine, 13, 376-376 (2015-12-03) Bacillus 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protective responses.Peter H Goff et al.Journal of virology, 89(6), 3221-3235 (2015-01-09) A Versatile Monoclonal Antibody Specific Against Human DAB2IP.Yintao Su et al.Monoclonal antibodies in immunodiagnosis and immunotherapy, 34(4), 246-250 (2015-08-25) Identification and functional characterization of the CSF1R gene from grass carp Ctenopharyngodon idellus and its use as a marker of monocytes/macrophages.Qiang Chen et al.Fish & shellfish immunology, 45(2), 386-398 (2015-05-10) Autoantibody Signatures Combined with Epstein-Barr Virus Capsid Antigen-IgA as a Biomarker Panel for the Detection of Nasopharyngeal Carcinoma.Yu-Hui Peng et al.Cancer prevention research (Philadelphia, Pa.), 8(8), 729-736 (2015-05-21) Release of nonstop ribosomes is essential.Heather A Feaga et al.mBio, 5(6), e01916-e01916 (2014-11-13) Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8.Yongdae Shin et al.Proceedings of the National 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