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Synthetic Route

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Articles

Peer-Reviewed Papers

A nonradioactive approach to investigate the metabolism of therapeutic peptides by tagging with 127i and using inductively-coupled plasma mass spectrometry analysis.Heng-Keang Lim et al.Drug metabolism and disposition: the biological fate of chemicals, 43(1), 17-26 (2014-10-16) An expanded eukaryotic genetic code.Jason W Chin et al.Science (New York, N.Y.), 301(5635), 964-967 (2003-08-16) Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT.Dirk Hellwig et al.European journal of nuclear medicine and molecular imaging, 32(9), 1041-1049 (2005-05-20) Investigation of iodine-123-labelled amino acid derivatives for imaging cerebral gliomas: uptake in human glioma cells and evaluation in stereotactically implanted C6 glioma rats.S Samnick et al.European journal of nuclear medicine, 27(10), 1543-1551 (2000-11-18) Evidence that the supE44 mutation of Escherichia coli is an amber suppressor allele of glnX and that it also suppresses ochre and opal nonsense mutations.B Singaravelan et al.Journal of bacteriology, 192(22), 6039-6044 (2010-09-14) An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.Ganesan Vaidyanathan et al.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(10), 1401-1406 (2011-05-31) The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.Jianming Xie et al.Nature biotechnology, 22(10), 1297-1301 (2004-09-21) Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase.V Reiland et al.Acta crystallographica. Section D, Biological crystallography, 60(Pt 10), 1738-1746 (2004-09-25) One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases.Charles E Melançon et al.Bioorganic & medicinal chemistry letters, 19(14), 3845-3847 (2009-04-29) p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.Samuel Samnick et al.European journal of nuclear medicine and molecular imaging, 31(4), 532-541 (2004-01-15) Para-[(123)I]iodo-L-phenylalanine in patients with pancreatic adenocarcinoma: tumour uptake, whole-body kinetics, dosimetry.D Hellwig et al.Nuklearmedizin. Nuclear medicine, 47(5), 220-224 (2008-10-15) Patients with recurrent glioblastoma multiforme. Initial experience with p-[(131)I]iodo-L-phenylalanine and external beam radiation therapy.F A Verburg et al.Nuklearmedizin. Nuclear medicine, 52(1), 36-42 (2013-01-11) Synthesis of peptide labelled with p-iodophenylalanine which corresponds to the first amphipathic region of apolipoprotein C-I.D R Harding et al.International journal of peptide and protein research, 26(2), 208-213 (1985-08-01) Phasing in iodine for structure determination.Zbigniew Dauter Nature biotechnology, 22(10), 1239-1240 (2004-10-08) [Metabolic studies of p-iodophenylalanine in the pancreas: a gateway to the development of radioiodinated amino acids for functional diagnosis].K Kawai et al.Kaku igaku. The Japanese journal of nuclear medicine, 25(11), 1263-1270 (1988-11-01) Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas.Ina Israel et al.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 66(4), 513-522 (2007-11-21) 123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.Veerle Kersemans et al.European journal of nuclear medicine and molecular imaging, 33(8), 919-927 (2006-03-31) Four color fret dye nucleotide terminators for DNA sequencing.T S Rao et al.Nucleosides, nucleotides & nucleic acids, 20(4-7), 673-676 (2001-09-21) Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions.R Karthikraj et al.Rapid communications in mass spectrometry : RCM, 26(11), 1385-1391 (2012-05-05) Site-specific incorporation of 4-iodo-L-phenylalanine through opal suppression.Koichiro Kodama et al.Journal of biochemistry, 148(2), 179-187 (2010-05-25) Initial evaluation of the feasibility of single photon emission tomography with p-[123 I]iodo-L-phenylalanine for routine brain tumour imaging.S Samnick et al.Nuclear medicine communications, 23(2), 121-130 (2002-03-14) The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit.B Chevrier et al.European journal of biochemistry, 237(2), 393-398 (1996-04-15) Synthesis and radioiodination of N-Boc-p-(tri-n-butylstannyl)-L-phenylalanine tetrafluorophenyl ester: preparation of a radiolabeled phenylalanine derivative for peptide synthesis.D S Wilbur et al.Bioconjugate chemistry, 4(6), 574-580 (1993-11-01) Action and efficacy of p-[131I]iodo-L-phenylalanine on primary human glioma cell cultures and rats with C6-gliomas.Bernd F M Romeike et al.Anticancer research, 24(6), 3971-3976 (2005-03-02) Intra-individual comparison of p-[123I]-iodo-L-phenylalanine and L-3-[123I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas.Dirk Hellwig et al.European journal of nuclear medicine and molecular imaging, 35(1), 24-31 (2007-09-12) A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe.Koichiro Kodama et al.Chembiochem : a European journal of chemical biology, 7(10), 1577-1581 (2006-09-14) Use of the Sonogashira coupling reaction for the "two-step" labeling of phenylalanine peptide side chains with organometallic compounds.Ulrich Hoffmanns et al.Bioconjugate chemistry, 17(1), 204-213 (2006-01-19)

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