Melting point	179-180 ºC

Symbol(GHS)	Xn
Hazard Codes	R21/22;R36/37/38
SDS/MSDS	S22;S26;S36/37/39

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Apollo	View & Download
Matrix	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Anionradicals from 5-halouracil substituted oriented DNA after X-irradiation at low temperatures.K Voit et al.Radiation and environmental biophysics, 25(3), 175-181 (1986-01-01) Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages.Junko Takeshita et al.The Journal of biological chemistry, 281(6), 3096-3104 (2005-12-06) Electron attachment to chlorouracil: a comparison between 6-ClU and 5-ClU.Stephan Denifl et al.The Journal of chemical physics, 120(2), 704-709 (2004-07-23) Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.Amritraj Patra et al.Nucleic acids research, 41(4), 2689-2697 (2013-01-01) Evaluation of the SOS chromotest for the detection of antimutagens.T Sato et al.Environmental and molecular mutagenesis, 17(4), 258-263 (1991-01-01) A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma.Liia D Vainchtein et al.Biomedical chromatography : BMC, 24(4), 374-386 (2009-08-04) The effect of histidine on the structure and antitumor activity of metal-5-halouracil complexes.U P Singh et al.Journal of inorganic biochemistry, 37(4), 325-339 (1989-12-01) Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue.Jeffrey P Henderson et al.The Journal of biological chemistry, 278(26), 23522-23528 (2003-04-23) Shape resonance spectra of uracil, 5-fluorouracil, and 5-chlorouracil.F Kossoski et al.The Journal of chemical physics, 140(2), 024317-024317 (2014-01-21) Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma.Marianne Berdugo Polak et al.Investigative ophthalmology & visual science, 49(7), 2993-3003 (2008-06-27) pH-Dependent configurations of a 5-chlorouracil-guanine base pair.Jacob A Theruvathu et al.Biochemistry, 48(47), 11312-11318 (2009-10-30) The genetic toxicology of 5-fluoropyrimidines and 5-chlorouracil.S M Morris Mutation research, 297(1), 39-51 (1993-07-01) Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair.Jacob A Theruvathu et al.Biochemistry, 48(31), 7539-7546 (2009-07-22) Hydrophilic interaction liquid chromatography-APCI-mass spectrometry determination of 5-fluorouracil in plasma and tissues.Rossella Pisano et al.Journal of pharmaceutical and biomedical analysis, 38(4), 738-745 (2005-06-22) Hypochlorous acid-induced base modifications in isolated calf thymus DNA.M Whiteman et al.Chemical research in toxicology, 10(11), 1240-1246 (1997-12-24) Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo.Matthew Whiteman et al.Biochemical and biophysical research communications, 296(4), 883-889 (2002-08-30) A spectroscopic investigations of anticancer drugs binding to bovine serum albumin.S Bakkialakshmi et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 88, 2-9 (2012-01-10) Comparative study of HOCl-inflicted damage to bacterial DNA ex vivo and within cells.Christine Suquet et al.Archives of biochemistry and biophysics, 493(2), 135-142 (2009-10-24) Polymerase incorporation and miscoding properties of 5-chlorouracil.Cherine H Kim et al.Chemical research in toxicology, 23(4), 740-748 (2010-01-29) 5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay.Qing Jiang et al.The Journal of biological chemistry, 278(35), 32834-32840 (2003-06-18) An improved resazurin-based cytotoxicity assay for hepatic cells.M K McMillian et al.Cell biology and toxicology, 18(3), 157-173 (2002-06-27) Highly sensitive determination of 5-fluorouracil in human plasma by capillary gas chromatography and negative ion chemical ionization mass spectrometry.R M Kok et al.Journal of chromatography, 343(1), 59-66 (1985-09-13) Synthesis and characterization of oligonucleotides containing 5-chlorocytosine.Joseph I Kang et al.Chemical research in toxicology, 17(9), 1236-1244 (2004-09-21) Micro scale. Rapid and simple determination of tegafur (FT) by high pressure liquid chromatography in plasma.M Ishikawa et al.Research communications in chemical pathology and pharmacology, 64(2), 347-350 (1989-05-01) Chemical evolution of a bacterium's genome.Philippe Marlière et al.Angewandte Chemie (International ed. in English), 50(31), 7109-7114 (2011-06-29) Toxicity study of uracil in dogs.E J Spicer et al.Journal of applied toxicology : JAT, 5(5), 333-338 (1985-10-01) Electron transfer processes in potassium collisions with 5-fluorouracil and 5-chlorouracil.F Ferreira da Silva et al.Physical chemistry chemical physics : PCCP, 13(48), 21621-21629 (2011-11-11)

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