Melting point	48-55 ºC
Flash point	>110 ºC

Symbol(GHS)	Xi
Hazard Codes	R36
SDS/MSDS	S26

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
Apollo	View & Download

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Peer-Reviewed Papers

Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.Ahmad Sharanek et al.Toxicological sciences : an official journal of the Society of Toxicology, 141(1), 244-253 (2014-06-29) Peptoid CCK receptor antagonists: pharmacological evaluation of CCKA, CCKB and mixed CCKA/B receptor antagonists.L Singh et al.European journal of pharmacology, 286(2), 185-191 (1995-11-14) Urea cycle disorder drug approved.Malini Guha Nature biotechnology, 31(4), 274-274 (2013-04-09) Obesity-induced endoplasmic reticulum stress suppresses nuclear factor-Y expression.Yulan Liu et al.Molecular and cellular biochemistry, 426(1-2), 47-54 (2016-11-12) Reduced delivery of epididymal adipocyte-derived exosomal resistin is essential for melatonin ameliorating hepatic steatosis in mice.Bohan Rong et al.Journal of pineal research, 66(4), e12561-e12561 (2019-01-20) Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.Wangqin Shu et al.Molecular and cellular biology, 40(3) (2019-11-13) Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis.Akhirunnesa Mily et al.BMC pulmonary medicine, 13, 23-23 (2013-04-18) Endoplasmic Reticulum (ER) Stress in Part Mediates Effects of Angiotensin II in Pancreatic Beta Cells.Latha Ramalingam et al.Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 2843-2853 (2020-09-05) The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation.Olivier Mansier et al.Cancers, 11(12) (2019-12-08) Comparison of Different Histone Deacetylase Inhibitors in Attenuating Inflammatory Pain in Rats.Yu Mao et al.Pain research & management, 2019, 1648919-1648919 (2019-02-28) Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma.Xiefang Yuan et al.Scientific reports, 8(1), 7950-7950 (2018-05-23) Total Analysis of Microcystins in Fish Tissue Using Laser Thermal Desorption-Atmospheric Pressure Chemical Ionization-High-Resolution Mass Spectrometry (LDTD-APCI-HRMS).Audrey Roy-Lachapelle et al.Journal of agricultural and food chemistry, 63(33), 7440-7449 (2015-07-28) Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets.J Y Chan et al.Diabetologia, 55(11), 2999-3009 (2012-08-16) Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.Sergey Lupachyk et al.Diabetes, 62(3), 944-952 (2013-02-01) 3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cells.Da-Hye Go et al.Oncotarget, 8(35), 58790-58800 (2017-09-25) Epithelial Cells Induce a Cyclo-Oxygenase-1-Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype.Michael J O'Sullivan et al.American journal of respiratory cell and molecular biology, 57(6), 683-691 (2017-07-15) Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.Wenyuan Huang et al.Cancer cell international, 19, 151-151 (2019-06-06) The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes.Ross M Tanis et al.Biochimica et biophysica acta, 1853(1), 213-221 (2014-12-03) The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.Karin Eigner et al.Scientific reports, 7(1), 17498-17498 (2017-12-14) Rare disease clinical research network's urea cycle consortium delivers a successful clinical trial to improve alternate pathway therapy.Pramod K Mistry Hepatology (Baltimore, Md.), 57(6), 2100-2102 (2012-10-20) Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.Meng He et al.Psychoneuroendocrinology, 104, 286-299 (2019-03-31) The endoplasmic reticulum stress response participates in connexin 43-mediated ossification of the posterior longitudinal ligament.Lei Shi et al.American journal of translational research, 11(7), 4113-4125 (2019-08-10) Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction.Min Zheng et al.International immunopharmacology, 15(3), 517-523 (2013-02-19) Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.Aidong Shan et al.Biochimica et biophysica acta. General subjects, 1863(5), 870-882 (2019-02-25) How sweet it isn't: a new formulation of sodium phenylbutyrate and the challenge of palatability for medicines for children.Michael Rieder Archives of disease in childhood, 97(12), 1080-1080 (2012-11-21) Endoplasmic reticulum stress induces epithelial-mesenchymal transition through autophagy via activation of c-Src kinase.Soo Young Moon et al.Nephron. Experimental nephrology, 126(3), 127-140 (2014-05-28) The endoplasmic reticulum stress and related signal pathway mediated the glyphosate-induced testosterone synthesis inhibition in TM3 cells.Yongpeng Xia et al.Environmental pollution (Barking, Essex : 1987), 260, 113949-113949 (2020-01-23) Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: protection by nifedipine.Khadija Syeda et al.Biochemical pharmacology, 86(9), 1338-1346 (2013-09-03) Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.Yuya Urano et al.Chemico-biological interactions, 296, 185-197 (2018-09-24) Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.Hilaire C Lam et al.The Journal of clinical investigation, 123(12), 5212-5230 (2013-11-10) Debika Datta et al.Cell death discovery, 4, 30-30 (2018-03-14)Mycobacterium fortuitum is a natural fish pathogen. It induces apoptosis in headkidney macrophages (HKM) of catfish, Clarias sp though the mechanism remains largely unknown. We observed M. fortuitum triggers calcium (Ca2+) insult in the sub-cellular compartments which elicits pro-apototic ER-stress... Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia.Yong Yang et al.Cell and tissue research, 379(3), 589-599 (2019-10-23) Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.He Huang et al.Autophagy, 9(2), 175-195 (2012-11-22) Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension.Peter Dromparis et al.Circulation, 127(1), 115-125 (2012-11-15) Analysis of individual and total microcystins in surface water by on-line preconcentration and desalting coupled to liquid chromatography tandem mass spectrometry.Gabriel Munoz et al.Journal of chromatography. A, 1516, 9-20 (2017-08-22) Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension.Masayuki Koyama et al.American journal of physiology. Heart and circulatory physiology, 306(9), H1314-H1323 (2014-03-13) (-)-Hydroxycitric acid attenuates endoplasmic reticulum stress-mediated alterations in 3T3-L1 adipocytes by protecting mitochondria and downregulating inflammatory markers.V M Nisha et al.Free radical research, 48(11), 1386-1396 (2014-09-02) Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.Norihiko Yokoi et al.Nature medicine, 21(1), 19-26 (2014-12-09) Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.Ke-Xue Li et al.European journal of pharmacology, 852, 90-98 (2019-03-10) Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress.Yong Zhou et al.Cancer science, 105(10), 1279-1287 (2014-08-05) Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy.Madhuri Chaurasia et al.Autophagy, 15(8), 1391-1406 (2019-02-19) Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle.Tae Woo Jung et al.Molecular and cellular endocrinology, 470, 26-33 (2017-11-08) Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.Anaïs Szpigel et al.Diabetologia, 61(2), 399-412 (2017-10-11) Glucosamine induces increased musclin gene expression through endoplasmic reticulum stress-induced unfolding protein response signaling pathways in mouse skeletal muscle cells.Qian Guo et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 95-105 (2019-01-03) Developing a new formulation of sodium phenylbutyrate.Nathalie Guffon et al.Archives of disease in childhood, 97(12), 1081-1085 (2012-09-04) Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways.Chongshan Dai et al.Biomolecules, 10(7) (2020-07-12) Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus.Hazel M Girvan et al.Journal of inorganic biochemistry, 188, 18-28 (2018-08-18) The activation of autophagy protects neurons and astrocytes against bilirubin-induced cytotoxicity.Mohammed Qaisiya et al.Neuroscience letters, 661, 96-103 (2017-10-03) Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.Di Liu et al.Biochemical and biophysical research communications, 494(1-2), 165-172 (2017-10-19) Growth inhibition of pancreatic cancer by experimental treatment with 4-phenylbutyrate is associated with increased expression of Connexin 43.Dmitriy I Dovzhanskiy et al.Oncology research, 20(2-3), 103-111 (2012-12-01) Nebulization prior to ionization for mechanistic studies of chemical reactions.Hong Zhang et al.Analytica chimica acta, 1107, 107-112 (2020-03-24) Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells.Xin Chou et al.Archives of toxicology, 93(4), 965-986 (2019-02-24) The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity.Consuelo Amantini et al.Oncotarget, 8(53), 90766-90780 (2017-12-07) Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.Kyoungsub Song et al.Hepatology (Baltimore, Md.), 58(5), 1681-1692 (2013-05-25) Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway.Ji Hyun Choi et al.Experimental & molecular medicine, 52(3), 423-437 (2020-03-04) Autosomal Dominant PTH Gene Signal Sequence Mutation in a Family With Familial Isolated Hypoparathyroidism.Luigia Cinque et al.The Journal of clinical endocrinology and metabolism, 102(11), 3961-3969 (2017-09-25) Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection.Yasir Alhamdi et al.PLoS pathogens, 11(5), e1004836-e1004836 (2015-05-15) Chan-Yen Kuo et al.Cancer research, 77(13), 3406-3416 (2017-05-24)Mutations and epigenetic inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) are major causes of clear-cell renal cell carcinoma (ccRCC) that may originate from chronic inflammation. However, the role of VHL loss of function in the development of ccRCC... Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways.Nikhil N Kulkarni et al.Molecular immunology, 63(2), 530-539 (2014-12-03) Neuroprotective Effects of Germinated Brown Rice in Rotenone-Induced Parkinson's-Like Disease Rats.Supin Chompoopong et al.Neuromolecular medicine, 18(3), 334-346 (2016-07-20) Effect of advanced glycation end product on paraoxonase 2 expression: Its impact on endoplasmic reticulum stress and inflammation in HUVECs.Ramya Ravi et al.Life sciences, 246, 117397-117397 (2020-02-08) Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.Xin Wen et al.Frontiers in physiology, 11, 868-868 (2020-10-06) Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection.Yasir Alhamdi et al.PLoS pathogens, 11(5), e1004836-e1004836 (2015-05-15) Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.Gamze Bora-Tatar et al.Bioorganic & medicinal chemistry, 17(14), 5219-5228 (2009-06-13) Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma.Gulab S Zode et al.The Journal of clinical investigation, 124(5), 1956-1965 (2014-04-03) Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.Agostino Marrazzo et al.European journal of medicinal chemistry, 46(1), 433-438 (2010-11-09) Chan-Yen Kuo et al.Cancer research, 77(13), 3406-3416 (2017-05-24)Mutations and epigenetic inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) are major causes of clear-cell renal cell carcinoma (ccRCC) that may originate from chronic inflammation. However, the role of VHL loss of function in the development of ccRCC... Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways.Nikhil N Kulkarni et al.Molecular immunology, 63(2), 530-539 (2014-12-03) Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.Kyoungsub Song et al.Hepatology (Baltimore, Md.), 58(5), 1681-1692 (2013-05-25) Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.Qian Deng et al.European journal of pharmacology, 826, 24-30 (2018-03-05) The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity.Consuelo Amantini et al.Oncotarget, 8(53), 90766-90780 (2017-12-07) Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway.Ji Hyun Choi et al.Experimental & molecular medicine, 52(3), 423-437 (2020-03-04) 4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum.Wei Zeng et al.Life sciences, 103(1), 15-24 (2014-03-22) Zearalenone induces apoptosis in bovine mammary epithelial cells by activating endoplasmic reticulum stress.YuRong Fu et al.Journal of dairy science, 102(11), 10543-10553 (2019-09-10) CYP2E1 regulates the development of radiation-induced pulmonary fibrosis via ER stress- and ROS-dependent mechanisms.Beomseok Son et al.American journal of physiology. Lung cellular and molecular physiology, 313(5), L916-L929 (2017-08-12) Matrine inhibits prostate cancer via activation of the unfolded protein response/endoplasmic reticulum stress signaling and reversal of epithelial to mesenchymal transition.Junli Chang et al.Molecular medicine reports, 18(1), 945-957 (2018-05-31) Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.Di Liu et al.Biochemical and biophysical research communications, 494(1-2), 165-172 (2017-10-19) Matrine Suppresses the ER-positive MCF Cells by Regulating Energy Metabolism and Endoplasmic Reticulum Stress Signaling Pathway.Yi Xiao et al.Phytotherapy research : PTR, 31(4), 671-679 (2017-02-12) Copper stress induces zebrafish central neural system myelin defects via WNT/NOTCH-hoxb5b signaling and pou3f1/fam168a/fam168b DNA methylation.Ting Zhang et al.Biochimica et biophysica acta. Gene regulatory mechanisms, 1863(10), 194612-194612 (2020-08-04) Mutation specific therapy in CF.Eitan Kerem Paediatric respiratory reviews, 7 Suppl 1, S166-S169 (2006-06-27) Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate.Wendy Smith et al.The Journal of pediatrics, 162(6), 1228-1234 (2013-01-18) Radioimmunoassay for ubenimex in human serum.M Koyama et al.Journal of pharmaceutical and biomedical analysis, 10(2-3), 137-140 (1992-02-01) Cholinergic drugs ameliorate endothelial dysfunction by decreasing O-GlcNAcylation via M3 AChR-AMPK-ER stress signaling.Yan-Ling Cui et al.Life sciences, 222, 1-12 (2019-02-21) Induction of apoptosis coupled to endoplasmic reticulum stress through regulation of CHOP and JNK in bone marrow mesenchymal stem cells from patients with systemic lupus erythematosusGuo G, et al. Journal of immunology research (2015) Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule.Sabrina Chriett et al.Scientific reports, 9(1), 742-742 (2019-01-27) Berberine Attenuates Macrophages Infiltration in Intracranial Aneurysms Potentially Through FAK/Grp78/UPR Axis.Kai Quan et al.Frontiers in pharmacology, 9, 565-565 (2018-06-15) Tetramethylpyrazine suppresses angiotensin II-induced soluble epoxide hydrolase expression in coronary endothelium via anti-ER stress mechanism.Shiu-Kwong Mak et al.Toxicology and applied pharmacology, 336, 84-93 (2017-10-27) Sinomenine Hydrochloride Inhibits the Metastasis of Human Glioblastoma Cells by Suppressing the Expression of Matrix Metalloproteinase-2/-9 and Reversing the Endogenous and Exogenous Epithelial-Mesenchymal Transition.Yumao Jiang et al.International journal of molecular sciences, 19(3) (2018-03-15) Endoplasmic reticulum stress mediates the arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.Xin-Yu Zhang et al.The international journal of biochemistry & cell biology, 68, 158-165 (2015-09-28) 4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.Antje Malo et al.Pancreas, 42(1), 92-101 (2012-08-15) Inhibition of Endoplasmic Reticulum Stress Attenuated Ethanol-Induced Exosomal miR-122 and Acute Liver Injury in Mice.Sheng Wang et al.Alcohol and alcoholism (Oxford, Oxfordshire), 54(5), 465-471 (2019-07-31) N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) attenuates silicotic fibrosis by suppressing apoptosis of alveolar type II epithelial cells via mediation of endoplasmic reticulum stress.Lijuan Zhang et al.Toxicology and applied pharmacology, 350, 1-10 (2018-04-24) Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.Yu-Yang Ma et al.Acta pharmacologica Sinica, 41(3), 404-414 (2019-11-09) Activation of the stress proteome as a mechanism for small molecule therapeutics.Rebecca Deering Brose et al.Human molecular genetics, 21(19), 4237-4252 (2012-07-04) MicroRNA-429 inhibits the migration and invasion of colon cancer cells by targeting PAK6/cofilin signaling.Xiangyang Tian et al.Oncology reports, 34(2), 707-714 (2015-06-11) Kaempferol induces hepatocellular carcinoma cell death via endoplasmic reticulum stress-CHOP-autophagy signaling pathway.Haiqing Guo et al.Oncotarget, 8(47), 82207-82216 (2017-11-16) Ethanol extract of propolis protects macrophages from oxidized low density lipoprotein-induced apoptosis by inhibiting CD36 expression and endoplasmic reticulum stress-C/EBP homologous protein pathway.Hua Tian et al.BMC complementary and alternative medicine, 15, 230-230 (2015-07-15) D4F alleviates macrophage-derived foam cell apoptosis by inhibiting CD36 expression and ER stress-CHOP pathway.Shutong Yao et al.Journal of lipid research, 56(4), 836-847 (2015-01-31) Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy.Shengchao Lin et al.The international journal of biochemistry & cell biology, 87, 54-68 (2017-04-11) Prostaglandin E1 protects hepatocytes against endoplasmic reticulum stress-induced apoptosis via protein kinase A-dependent induction of glucose-regulated protein 78 expression.Fang-Wan Yang et al.World journal of gastroenterology, 23(40), 7253-7264 (2017-11-17) The regulatory mechanism of 4-phenylbutyric acid against ER stress-induced autophagy in human gingival fibroblasts.Do-Sung Kim et al.Archives of pharmacal research, 35(7), 1269-1278 (2012-08-07) Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice.Jian-Qing Wang et al.Toxicology and applied pharmacology, 266(2), 307-316 (2012-11-24) Cigarette Smoke Extract Promotes Human Lung Myofibroblast Differentiation by the Induction of Endoplasmic Reticulum Stress.Min Song et al.Respiration; international review of thoracic diseases, 98(4), 347-356 (2019-08-16) RTN1-C is involved in high glucose-aggravated neuronal cell subjected to oxygen-glucose deprivation and reoxygenation injury via endoplasmic reticulum stress.Muya Lin et al.Brain research bulletin, 149, 129-136 (2019-04-20) c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy.Xuezheng Li et al.Diabetes, 62(2), 599-608 (2012-09-11) Protective effects of Danzhi jiangtang capsule on vascular endothelial damages induced by high-fat diet and palmitic acid.Yunxia Lu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 107, 1631-1640 (2018-09-28) Improved liver function and relieved pruritus after 4-phenylbutyrate therapy in a patient with progressive familial intrahepatic cholestasis type 2.Sotaro Naoi et al.The Journal of pediatrics, 164(5), 1219-1227 (2014-02-18) Brown rice and its component, γ-oryzanol, attenuate the preference for high-fat diet by decreasing hypothalamic endoplasmic reticulum stress in mice.Chisayo Kozuka et al.Diabetes, 61(12), 3084-3093 (2012-07-25) No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.Elisabeth Kemter et al.The Journal of biological chemistry, 289(15), 10715-10726 (2014-02-26) Low-frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in PTX-resistant PC-3 cells via the endoplasmic reticulum stress-mediated PI3K/Akt/mTOR signaling pathway.Yuqi Wu et al.OncoTargets and therapy, 11, 5621-5630 (2018-09-27) Oridonin Induces Apoptosis of Laryngeal Carcinoma via Endoplasmic Reticulum Stress.Bo Kou et al.Cancer management and research, 12, 8387-8396 (2020-09-29) Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression.Seung Un Seo et al.Biochemical and biophysical research communications, 498(4), 849-854 (2018-03-15) Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue.Lu Gan et al.Frontiers in immunology, 8, 1507-1507 (2017-12-19) 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.Ryoichi Tomiyama et al.Journal of cellular physiology, 233(2), 1671-1684 (2017-07-07) Trehalose inhibits H2O2-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activation.Zhijie Gao et al.International journal of medical sciences, 15(10), 1014-1024 (2018-07-18) Activation of CaMKII via ER-stress mediates coxsackievirus B3-induced cardiomyocyte apoptosis.Jungang Nie et al.Cell biology international, 44(2), 488-498 (2019-10-22) Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress.Xia Gao et al.Biochimica et biophysica acta, 1852(12), 2689-2699 (2015-09-24) Grape seed proanthocyanidins protect cardiomyocytes against hypoxia/reoxygenation injury by attenuating endoplasmic reticulum stress through PERK/eIF2α pathway.Xin Wang et al.Molecular medicine reports, 16(6), 9189-9196 (2017-10-19) Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells.Aritra Mallik et al.Biochemical and biophysical research communications, 502(3), 370-374 (2018-06-01) Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.Kangping Liu et al.Biological trace element research, 194(2), 570-580 (2019-07-03) Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress‑related autophagy in hepatocellular carcinoma.Dong Liu et al.Oncology reports, 40(4), 2206-2214 (2018-08-02) STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress.Yan Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 110022-110022 (2020-02-29) Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells.Qihui Luo et al.BioMed research international, 2018, 5241941-5241941 (2019-01-24) Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation.Keith A Bailey et al.Scientific reports, 7(1), 8196-8196 (2017-08-16) Involvement of ER stress and reactive oxygen species generation in anti-cancer effect of CKD-516 for lung cancer.Soo Jin Kim et al.Cancer chemotherapy and pharmacology, 85(4), 685-697 (2020-03-12) Functional rescue of mutant ABCA1 proteins by sodium 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