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Peer-Reviewed Papers

Rosemary extracts improve flow-mediated dilatation of the brachial artery and plasma PAI-1 activity in healthy young volunteers.Andreja Sinkovic et al.Phytotherapy research : PTR, 25(3), 402-407 (2010-08-25) Protective effect of carnosol on lung injury induced by intestinal ischemia/reperfusion.Xiao-Feng Tian et al.Surgery today, 40(9), 858-865 (2010-08-27) Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma.Oliver Rau et al.Planta medica, 72(10), 881-887 (2006-07-22) Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells.Yosei Tamaki et al.Planta medica, 76(7), 683-688 (2009-11-27) Carnosol, a constituent of Zyflamend, inhibits aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and mutagenesis.Arash Mohebati et al.Cancer prevention research (Philadelphia, Pa.), 5(4), 593-602 (2012-03-01) The plant phenolic diterpene carnosol suppresses sodium nitroprusside-induced toxicity in c6 glial cells.Sang Yong Kim et al.Journal of agricultural and food chemistry, 58(3), 1543-1550 (2010-01-16) Relevance of carnosic acid, carnosol, and rosmarinic acid concentrations in the in vitro antioxidant and antimicrobial activities of Rosmarinus officinalis (L.) methanolic extracts.Maria J Jordán et al.Journal of agricultural and food chemistry, 60(38), 9603-9608 (2012-09-11) Degradation study of carnosic acid, carnosol, rosmarinic acid, and rosemary extract (Rosmarinus officinalis L.) assessed using HPLC.Ying Zhang et al.Journal of agricultural and food chemistry, 60(36), 9305-9314 (2012-08-14) Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L.Daniele G Machado et al.Food chemistry, 136(2), 999-1005 (2012-11-06) Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean Lamiaceae Sphacele chamaedryoides (Balbis) Briq.Carlos Areche et al.The Journal of pharmacy and pharmacology, 61(12), 1689-1697 (2009-12-05) Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary.Auxiliadora López-Jiménez et al.European journal of nutrition, 52(1), 85-95 (2011-12-17) Carnosol: a promising anti-cancer and anti-inflammatory agent.Jeremy J Johnson Cancer letters, 305(1), 1-7 (2011-03-09) Dual mechanisms of NF-kappaB inhibition in carnosol-treated endothelial cells.Kai-Cheng Lian et al.Toxicology and applied pharmacology, 245(1), 21-35 (2010-02-02) Storage method, drying processes and extraction procedures strongly affect the phenolic fraction of rosemary leaves: an HPLC/DAD/MS study.N Mulinacci et al.Talanta, 85(1), 167-176 (2011-06-08) Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - studies in electrophile response element transgenic mice.Trude Rakel Balstad et al.Molecular nutrition & food research, 55(2), 185-197 (2010-09-10) The antioxidant effect of carnosol in bovine aortic endothelial cells is mainly mediated via estrogen receptor α pathway.Pi-wen Zhao et al.Biological & pharmaceutical bulletin, 35(11), 1947-1955 (2012-09-14) Carnosic acid induces the NAD(P)H: quinone oxidoreductase 1 expression in rat clone 9 cells through the p38/nuclear factor erythroid-2 related factor 2 pathway.Chia-Wen Tsai et al.The Journal of nutrition, 141(12), 2119-2125 (2011-10-28) ent-Rosane and abietane diterpenoids as cancer chemopreventive agents.Marvin J Núñez et al.Phytochemistry, 72(4-5), 385-390 (2011-02-15) Antioxidant and Antimicrobial Activity of Rosemary, Pomegranate and Olive Extracts in Fish Patties.Lorena Martínez et al.Antioxidants (Basel, Switzerland), 8(4) (2019-04-17) Antimicrobial activity of Rosmarinus officinalis against oral pathogens: relevance of carnosic acid and carnosol.Wagner A Bernardes et al.Chemistry & biodiversity, 7(7), 1835-1840 (2010-07-27) Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention.Jeremy J Johnson et al.Cancer prevention research (Philadelphia, Pa.), 3(9), 1112-1123 (2010-08-26) Effect of Rosemarinus officinalis L. on MMP-9, MCP-1 levels, and cell migration in RAW 264.7 and smooth muscle cells.In Gyeong Chae et al.Journal of medicinal food, 15(10), 879-886 (2012-09-19) Antiangiogenic effect of carnosic acid and carnosol, neuroprotective compounds in rosemary leaves.Tomoko Kayashima et al.Bioscience, biotechnology, and biochemistry, 76(1), 115-119 (2012-01-11) Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells.Sung-Jun Kim et al.Neuroreport, 17(16), 1729-1733 (2006-10-19) Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara.Masahiro Tada et al.Chemical & pharmaceutical bulletin, 58(1), 27-29 (2010-01-05) Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival.Chien-chung Chen et al.Acta pharmacologica Sinica, 32(1), 62-69 (2010-12-15) Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.Fabrice H F Pierre et al.The American journal of clinical nutrition, 98(5), 1255-1262 (2013-09-13) Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice.Melissa Raboni Alves Rodrigues et al.Journal of ethnopharmacology, 139(2), 519-526 (2011-12-14) Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.Julia Bauer et al.The Journal of pharmacology and experimental therapeutics, 342(1), 169-176 (2012-04-19)

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