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Synthetic Route

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Articles

Peer-Reviewed Papers

Production of N-acetyl-D-neuraminic acid using two sequential enzymes overexpressed as double-tagged fusion proteins.Tzu-Hsien Wang et al.BMC biotechnology, 9, 63-63 (2009-07-10) Coupled bioconversion for preparation of N-acetyl-D: -neuraminic acid using immobilized N-acetyl-D: -glucosamine-2-epimerase and N-acetyl-D: -neuraminic acid lyase.Shiyuan Hu et al.Applied microbiology and biotechnology, 85(5), 1383-1391 (2009-08-27) X-ray-excited optical luminescence of protein crystals: a new tool for studying radiation damage during diffraction data collection.Robin L Owen et al.Acta crystallographica. Section D, Biological crystallography, 68(Pt 5), 505-510 (2012-04-25) Molecular characterization of a novel N-acetylneuraminate lyase from Lactobacillus plantarum WCFS1.Guiomar Sánchez-Carrón et al.Applied and environmental microbiology, 77(7), 2471-2478 (2011-02-15) Production of N-acetyl-D-neuraminic acid by use of an efficient spore surface display system.Xiaoman Xu et al.Applied and environmental microbiology, 77(10), 3197-3201 (2011-03-29) Asymmetric transformations involving 1,2-dicarbonyl compounds as pronucleophiles.Wilfried Raimondi et al.Chemical communications (Cambridge, England), 48(54), 6763-6775 (2012-06-02) Homology modeling and molecular dynamics study on N-acetylneuraminate lyase.Hui-Ying Chu et al.Journal of molecular modeling, 15(3), 323-328 (2008-12-06) Glycomimicry: display of the GM3 sugar epitope on Escherichia coli and Salmonella enterica sv Typhimurium.Karin Ilg et al.Glycobiology, 20(10), 1289-1297 (2010-06-25) The sialic acids. I. The structure and enzymatic synthesis of N-acetylneuraminic acid.D G COMB et al.The Journal of biological chemistry, 235, 2529-2537 (1960-09-01) Requirement of purine and pyrimidine synthesis for colonization of the mouse intestine by Escherichia coli.Jacqueline Vogel-Scheel et al.Applied and environmental microbiology, 76(15), 5181-5187 (2010-06-22) Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.Ivan Campeotto et al.Journal of molecular biology, 404(1), 56-69 (2010-09-10) An efficient method for N-acetyl-D-neuraminic acid production using coupled bacterial cells with a safe temperature-induced system.Yinan Zhang et al.Applied microbiology and biotechnology, 86(2), 481-489 (2009-11-06) The quaternary structure of Escherichia coli N-acetylneuraminate lyase is essential for functional expression.Sean R A Devenish et al.Biochemical and biophysical research communications, 388(1), 107-111 (2009-08-04) Chemistry, metabolism, and biological functions of sialic acids.R Schauer Advances in carbohydrate chemistry and biochemistry, 40, 131-234 (1982-01-01) Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.Rachel A North et al.Acta crystallographica. Section F, Structural biology and crystallization communications, 69(Pt 3), 306-312 (2013-03-23) [Cloning and expression of N-acetyl-D-neuraminic acid aldolase in Escherichia coli].Wen-liu Yang et al.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 39(1), 57-63 (2010-02-23) Protein solubility and differential proteomic profiling of recombinant Escherichia coli overexpressing double-tagged fusion proteins.Chung-Hsien Cheng et al.Microbial cell factories, 9, 63-63 (2010-08-31) Modelling the reaction course of N-acetylneuraminic acid synthesis from N-acetyl-D-glucosamine--new strategies for the optimisation of neuraminic acid synthesis.Vera Zimmermann et al.Applied microbiology and biotechnology, 76(3), 597-605 (2007-07-03) Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives.Li Ding et al.Chemical communications (Cambridge, England), 47(30), 8691-8693 (2011-07-05) Parallel chemoenzymatic synthesis of sialosides containing a C5-diversified sialic acid.Hongzhi Cao et al.Bioorganic & medicinal chemistry letters, 19(20), 5869-5871 (2009-09-11) One-pot bio-synthesis: N-acetyl-D-neuraminic acid production by a powerful engineered whole-cell catalyst.Fei Tao et al.Scientific reports, 1, 142-142 (2012-02-23) Blood-based biomarkers can differentiate ulcerative colitis from Crohn's disease and noninflammatory diarrhea.Robert Burakoff et al.Inflammatory bowel diseases, 17(8), 1719-1725 (2011-07-12) Edwardsiella tarda sialidase: pathogenicity involvement and vaccine potential.Ren-ping Jin et al.Fish & shellfish immunology, 33(3), 514-521 (2012-06-19) Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251.Chien-Yu Chou et al.The Journal of biological chemistry, 286(16), 14057-14064 (2011-01-29) 4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibition.Travis J Riedel et al.Biochimica et biophysica acta, 1822(10), 1544-1552 (2012-07-10) Pasteurella multocida sialic acid aldolase: a promising biocatalyst.Yanhong Li et al.Applied microbiology and biotechnology, 79(6), 963-970 (2008-06-04) The capability of catabolic utilization of N-acetylneuraminic acid, a sialic acid, is essential for Vibrio vulnificus pathogenesis.Hee Gon Jeong et al.Infection and immunity, 77(8), 3209-3217 (2009-06-03) Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida.Nhung Huynh et al.Biochemistry, 52(47), 8570-8579 (2013-10-25) Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis.Varun Bhaskar et al.Proteins, 79(4), 1132-1142 (2011-02-05) A crosslinked inclusion body process for sialic acid synthesis.Jozef Nahálka et al.Journal of biotechnology, 134(1-2), 146-153 (2008-03-04)

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