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Computational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases.M L Bellows et al.Current drug targets, 11(3), 264-278 (2010-03-10) Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.Priscila O de Giuseppe et al.PloS one, 7(9), e44282-e44282 (2012-09-08) [PNP (purine nucleoside phosphorylase) deficiency].Atsuo Taniguchi Nihon rinsho. Japanese journal of clinical medicine, 61 Suppl 1, 372-376 (2003-03-13) The enzymatic synthesis of purine ribosides.H M KALCKAR The Journal of biological chemistry, 167(2), 477-486 (1947-02-01) Complete sequencing and characterization of 21,243 full-length human cDNAs.Toshio Ota et al.Nature genetics, 36(1), 40-45 (2004-01-01) Normal uric acid concentrations in a purine nucleoside phosphorylase (PNP) deficient child presenting with severe chicken pox, possible immunodeficiency and developmental delay.R J Hallett et al.Advances in experimental medicine and biology, 370, 387-389 (1994-01-01) Purine nucleoside phosphorylase: a fortuitous cytosolic arsenate reductase?Michael P Waalkes et al.Toxicological sciences : an official journal of the Society of Toxicology, 70(1), 1-3 (2002-10-22) Purine nucleoside phosphorylase inhibitors in T-cell malignancies.Shanta Bantia et al.Current opinion in drug discovery & development, 7(2), 243-247 (2004-12-18) Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient.U Pannicke et al.Human genetics, 98(6), 706-709 (1996-12-01) The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models.Candida Deves et al.Bone, 52(1), 167-175 (2012-10-03) Initial characterization of the human central proteome.Thomas R Burkard et al.BMC systems biology, 5, 17-17 (2011-01-29) Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.Lizhi Yu et al.Environmental health perspectives, 111(11), 1421-1427 (2003-08-21) Effect of asynchronous transfer on bovine embryonic development and relationship with early cycle uterine proteome profiles.A M Ledgard et al.Reproduction, fertility, and development, 24(7), 962-972 (2012-09-01) Extracellular guanosine regulates extracellular adenosine levels.Edwin K Jackson et al.American journal of physiology. Cell physiology, 304(5), C406-C421 (2012-12-18) Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.R G Silva et al.Current drug targets, 8(3), 413-422 (2007-03-14) Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway.Camille Mary et al.PloS one, 7(12), e52877-e52877 (2013-01-04) The rare fluorinated natural products and biotechnological prospects for fluorine enzymology.K K Jason Chan et al.Methods in enzymology, 516, 219-235 (2012-10-05) Methylthioadenosine phosphorylase inactivation depends on gene deletion in laryngeal squamous cell carcinoma.Laura Conde et al.Histopathology, 61(6), 1082-1088 (2012-10-02) Primary T-cell immunodeficiencies Clinical Immunology (Orlando, Fla.), 54(7), 489-508 (2019) Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization.S R Williams et al.Nucleic acids research, 12(14), 5779-5787 (1984-07-25) Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.P E Morris et al.Current pharmaceutical design, 6(9), 943-959 (2000-06-01) Randomised clinical trial: pre-dosing with taribavirin before starting pegylated interferon vs. standard combination regimen in treatment-naïve patients with chronic hepatitis C genotype 1.M Palmer et al.Alimentary pharmacology & therapeutics, 36(4), 370-378 (2012-06-20) Reduction of dimethylarsinic acid to the highly toxic dimethylarsinous acid by rats and rat liver cytosol.Balázs Németi et al.Chemical research in toxicology, 26(3), 432-443 (2013-02-19) Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.Vern L Schramm Biochimica et biophysica acta, 1587(2-3), 107-117 (2002-06-27) Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state.Beata Wielgus-Kutrowska et al.Bioorganic & medicinal chemistry, 20(22), 6758-6769 (2012-10-09) A purine nucleoside phosphorylase in Solanum tuberosum L. (potato) with specificity for cytokinins contributes to the duration of tuber endodormancy.Jennifer R Bromley et al.The Biochemical journal, 458(2), 225-237 (2013-12-12) DNA sequence and analysis of human chromosome 9.S J Humphray et al.Nature, 429(6990), 369-374 (2004-05-28) Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative.Johan Vande Voorde et al.Biochemical pharmacology, 83(10), 1358-1363 (2012-03-01) [Nucleosides of 1,2,4-triazole: potentialities and restrictions of chemo-enzymatic method for synthesis].I D Konstantinova et al.Bioorganicheskaia khimiia, 39(1), 61-80 (2013-07-13) [Adenosine deaminase (ADA), 5'-nucleotidase (5'N) and purine nucleoside phosphorylase (PNP) in lympho- and myeloproliferative disorders].K Warzocha et al.Przeglad lekarski, 51(12), 531-535 (1994-01-01) Enzymes of the human erythrocyte. I. Purine nucleoside phosphorylase; isolation procedure.K K TSUBOI et al.The Journal of biological chemistry, 224(2), 879-887 (1957-02-01) Significantly decreased methylthioadenosine phosphorylase expression in malignant melanoma.Thilo Gambichler et al.The American Journal of dermatopathology, 34(7), 777-779 (2012-09-25) Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase.Shanzhi Wang et al.Biochemistry, 53(9), 1527-1535 (2014-02-08) [Purine nucleoside phosphorylase (PNP)].Atsuo Taniguchi Nihon rinsho. Japanese journal of clinical medicine, 61 Suppl 1, 85-90 (2003-03-13) In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.Eric J Sorscher et al.Cancer chemotherapy and pharmacology, 70(2), 321-329 (2012-07-05) [Purine nucleoside phosphorylase (PNP)].T Sakiyama Nihon rinsho. Japanese journal of clinical medicine, 54(12), 3220-3225 (1996-12-01) Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesis.George Liechti et al.Journal of bacteriology, 194(4), 839-854 (2011-12-24) Nucleotide degradation and ribose salvage in yeast.Yi-Fan Xu et al.Molecular systems biology, 9, 665-665 (2013-05-15) Caught in the act. Femtochemistry opens the lid on biology's third vital criterion.Philip Hunter EMBO reports, 14(1), 36-38 (2012-12-12) An analysis of the myocardial transcriptome in a mouse model of cardiac dysfunction with decreased cholinergic neurotransmission.Ashbeel Roy et al.PloS one, 7(6), e39997-e39997 (2012-07-07) Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells.Baiqing Tang et al.Cancer biology & therapy, 13(11), 1082-1090 (2012-07-25) Deregulation of protein methylation in melanoma.Katharina Limm et al.European journal of cancer (Oxford, England : 1990), 49(6), 1305-1313 (2012-12-26) [Purine nucleoside phosphorylase].L G Pogosian et al.Biomeditsinskaia khimiia, 59(5), 483-497 (2014-02-01) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).Daniela S Gerhard et al.Genome research, 14(10B), 2121-2127 (2004-10-19) [Purine nucleoside phosphorylase (PNP) deficiency].T Sakiyama Nihon rinsho. Japanese journal of clinical medicine, 54(12), 3328-3332 (1996-12-01) [Purine nucleoside phosphorylase deficiency].Y Sakiyama Ryoikibetsu shokogun shirizu, (32)(32), 43-45 (2001-02-24) Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE).Katharina von Löhneysen et al.PloS one, 7(4), e34237-e34237 (2012-04-18) Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.M R Aust et al.American journal of human genetics, 51(4), 763-772 (1992-10-01) Catalytic site conformations in human PNP by 19F-NMR and crystallography.Javier Suarez et al.Chemistry & biology, 20(2), 212-222 (2013-02-27) Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.Rong Guan et al.Biochemistry, 52(46), 8313-8322 (2013-10-24) Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disordersJohnston S B and Raines R T Biochemistry, 54(7), 1576-1582 (2015) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.Sharon Gauci et al.Analytical chemistry, 81(11), 4493-4501 (2009-05-06) Role of disulfide bonds in conformational stability and folding of 5'-deoxy-5'-methylthioadenosine phosphorylase II from the hyperthermophilic archaeon Sulfolobus solfataricus.Giovanna Cacciapuoti et al.Biochimica et biophysica acta, 1824(10), 1136-1143 (2012-07-04) Homozygous deletions of cadherin genes in chondrosarcoma-an array comparative genomic hybridization study.Tarja Niini et al.Cancer genetics, 205(11), 588-593 (2012-11-14) Distortional binding of transition state analogs to human purine nucleoside phosphorylase probed by magic angle spinning solid-state NMR.Mathew J Vetticatt et al.Proceedings of the National Academy of Sciences of the United States of America, 110(40), 15991-15996 (2013-09-18) Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution.S E Ealick et al.The Journal of biological chemistry, 265(3), 1812-1820 (1990-01-25) Homooligomerization is needed for stability: a molecular modelling and solution study of Escherichia coli purine nucleoside phosphorylase.Branimir Bertoša et al.The FEBS journal, 281(7), 1860-1871 (2014-05-03) A study on the interaction of rhodamine B with methylthioadenosine phosphorylase protein sourced from an Antarctic soil metagenomic library.Paulina Bartasun et al.PloS one, 8(1), e55697-e55697 (2013-02-06) [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].Andrzej Lewandowicz Postepy biochemii, 50(3), 218-227 (2005-04-13) [Phosphorolysis and hydrolysis of purine ribosides by enzymes from yeast].L A HEPPEL et al.The Journal of biological chemistry, 198(2), 683-694 (1952-10-01) Assessment of emerging biomarkers of liver injury in human subjects.Shelli Schomaker et al.Toxicological sciences : an official journal of the Society of Toxicology, 132(2), 276-283 (2013-01-23) Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.Richard R Furman et al.Seminars in oncology, 34(6 Suppl 5), S29-S34 (2007-12-19) Enzymatic synthesis of highly fluorescent 8-azapurine ribosides using a purine nucleoside phosphorylase reverse reaction: variable ribosylation sites.Alicja Stachelska-Wierzchowska et al.Molecules (Basel, Switzerland), 18(10), 12587-12598 (2013-10-16) Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.Keith Clinch et al.Bioorganic & medicinal chemistry, 20(17), 5181-5187 (2012-08-03) The evolution of catalytic residues and enzyme mechanism within the bacterial nucleoside phosphorylase superfamily 1.Anke Konrad et al.Gene, 510(2), 154-161 (2012-09-13) Association between rs10118757(A/G) in methylthioadenosine phosphorylase gene and coronary artery disease in Chinese Hans.Xiaofei Lv et al.Gene, 526(2), 344-346 (2013-03-07) Continuous enzyme-coupled assay of phosphate- or pyrophosphate-releasing enzymes.Antonio S Guillén Suárez et al.BioTechniques, 53(2), 99-103 (2012-10-04) [Purine nucleoside phosphorylase inhibitors and their clinical significance].L G Pogosian et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 80(5), 95-104 (2009-03-03) Purine nucleoside phosphorylase from human erythrocytes. IV. Crystallization and some properties.R P Agarwal et al.The Journal of biological chemistry, 244(4), 644-647 (1969-02-25) Experimental cerebral malaria is suppressed by disruption of nucleoside transporter 1 but not purine nucleoside phosphorylase.Mamoru Niikura et al.Biochemical and biophysical research communications, 432(3), 504-508 (2013-02-14) Disorders of purines and pyrimidines Handbook of Clinical Neurology, 827-838 (2014) Transition states and inhibitors of the purine nucleoside phosphorylase family.Erika A Taylor Ringia et al.Current topics in medicinal chemistry, 5(13), 1237-1258 (2005-11-25) AS3MT, GSTO, and PNP polymorphisms: impact on arsenic methylation and implications for disease susceptibility.Ray Antonelli et al.Environmental research, 132, 156-167 (2014-05-06) [Purine nucleoside phosphorylase (PNP) deficiency].S Sumi et al.Ryoikibetsu shokogun shirizu, (18 Pt 1)(18 Pt 1), 458-459 (1998-05-20) [Influence of ionizing radiation on enzymatic activity and state of nucleus-nucleolar apparatus in rat hepatocytes].L S Nersesova et al.Radiatsionnaia biologiia, radioecologiia, 53(1), 55-62 (2013-05-25) Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides.Xinrui Zhou et al.The FEBS journal, 280(6), 1475-1490 (2013-01-22) Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies.Eyal Grunebaum et al.Current opinion in allergy and clinical immunology, 13(6), 630-638 (2013-10-12) Lack of expression of MTAP in uncommon T-cell lymphomas.Joseph R Bertino et al.Clinical lymphoma, myeloma & leukemia, 12(5), 306-309 (2012-10-09) A human purine nucleoside phosphorylase deficiency caused by a single base change.S R Williams et al.The Journal of biological chemistry, 262(5), 2332-2338 (1987-02-15) Improved synthesis of 2'-deoxyadenosine and 5-methyluridine by Escherichia coli using an auto-induction system.Juan Xiong et al.World journal of microbiology & biotechnology, 28(2), 721-727 (2012-07-19) Mycoplasma hyorhinis-encoded purine nucleoside phosphorylase: kinetic properties and its effect on the cytostatic potential of purine-based anticancer drugs.Johan Vande Voorde et al.Molecular pharmacology, 84(6), 865-875 (2013-09-27) Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.Sean B Johnston et al.PloS one, 10(1), e0116898-e0116898 (2015-01-22) Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis.Kajal Buckoreelall et al.Journal of bacteriology, 193(20), 5668-5674 (2011-08-09) Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus.P P Saunders et al.The Journal of biological chemistry, 244(13), 3691-3697 (1969-07-10) Purine nucleoside phosphorylase activity decline is linked to the decay of the trimeric form of the enzyme.Beata Wielgus-Kutrowska et al.Archives of biochemistry and biophysics, 549, 40-48 (2014-04-02)

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