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Peer-Reviewed Papers

Mood stabilizer augmentation in apparently "unipolar" MDD: predictors of response in the naturalistic French national EPIDEP study.Elie G Hantouche et al.Journal of affective disorders, 84(2-3), 243-249 (2005-02-15) Energy Metabolism and Mitochondrial Superoxide Anion Production in Pre-symptomatic Striatal Neurons Derived from Human-Induced Pluripotent Stem Cells Expressing Mutant Huntingtin.James Hamilton et al.Molecular neurobiology, 57(2), 668-684 (2019-08-23) Mood stabilizer augmentation in apparently "unipolar" MDD: predictors of response in the naturalistic French national EPIDEP study.Elie G Hantouche et al.Journal of affective disorders, 84(2-3), 243-249 (2005-02-15) Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries.Erica Elisa Ferrandi et al.The FEBS journal, 282(15), 2879-2894 (2015-06-03) Characterization of the anticonvulsant profile of valpromide derivatives.Silvina M Tasso et al.Bioorganic & medicinal chemistry, 12(14), 3857-3869 (2004-06-24) Valproic acid induces apoptosis in differentiating hippocampal neurons by the release of tumor necrosis factor-alpha from activated astrocytesWang C, et al. Neuroscience Letters, 497(2), 122-127 (2011) Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition.Reecha D Shah et al.Journal of cellular biochemistry, 114(4), 854-863 (2012-10-26) Histone deacetylases are required for amphibian tail and limb regeneration but not development.Amy J Taylor et al.Mechanisms of development, 129(9-12), 208-218 (2012-09-06) Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.Karine Cambon et al.Molecular therapy. Methods & clinical development, 5, 259-276 (2017-06-13) MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates.Romina Aron Badin et al.Nature communications, 10(1), 4357-4357 (2019-09-27) [Valpromide poisoning associated with circulatory collapse].Benoît Trojak et al.Therapie, 60(6), 595-597 (2006-03-25) Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.Akinobu Okada et al.Birth defects research. Part A, Clinical and molecular teratology, 73(4), 229-238 (2005-03-31) Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries.Erica Elisa Ferrandi et al.The FEBS journal, 282(15), 2879-2894 (2015-06-03) Mood stabilizers inhibit cytomegalovirus infection.Sara Ornaghi et al.Virology, 499, 121-135 (2016-09-23) Energy Metabolism and Mitochondrial Superoxide Anion Production in Pre-symptomatic Striatal Neurons Derived from Human-Induced Pluripotent Stem Cells Expressing Mutant Huntingtin.James Hamilton et al.Molecular neurobiology, 57(2), 668-684 (2019-08-23) Mood-stabilizers: the archeology of the concept.Margaret Harris et al.Bipolar disorders, 5(6), 446-452 (2003-11-26) Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors.Simona Dedoni et al.The Journal of pharmacology and experimental therapeutics, 370(3), 490-503 (2019-07-17) Management of epilepsy in adults. Diagnosis guidelines.Louis F Trost et al.Postgraduate medicine, 118(6), 22-26 (2005-12-31) The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells.Tomas Groh et al.International journal of oncology, 47(1), 343-352 (2015-05-13) [Deep lactic acidosis after valproate self-poisoning].D Blayac et al.Annales francaises d'anesthesie et de reanimation, 23(10), 1007-1010 (2004-10-27) Catalytic mechanism of limonene epoxide hydrolase, a theoretical study.Kathrin H Hopmann et al.Journal of the American Chemical Society, 127(41), 14339-14347 (2005-10-13) Exposure to valproic acid inhibits chondrogenesis and osteogenesis in mid-organogenesis mouse limbs.France-Hélène Paradis et al.Toxicological sciences : an official journal of the Society of Toxicology, 131(1), 234-241 (2012-10-09) Clinical pharmacology of valpromide.M Bialer Clinical pharmacokinetics, 20(2), 114-122 (1991-02-01) Amidic modification of valproic acid reduces skeletal teratogenicity in mice.Akinobu Okada et al.Birth defects research. Part B, Developmental and reproductive toxicology, 71(1), 47-53 (2004-03-03) The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior.J A Shimshoni et al.Molecular pharmacology, 71(3), 884-892 (2006-12-15) Valproic acid downregulates Cdk5 activity via the transcription of the p35 mRNA.Miyuki Takahashi et al.Biochemical and biophysical research communications, 447(4), 678-682 (2014-04-24) Valproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression.Zhiqi Xie et al.Oncoimmunology, 9(1), 1734268-1734268 (2020-03-12) Polycomb homologs are involved in teratogenicity of valproic acid in mice.Akinobu Okada et al.Birth defects research. Part A, Clinical and molecular teratology, 70(11), 870-879 (2004-11-04) Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells.Xiao-Chuan Wang et al.Neurochemical research, 33(6), 1138-1144 (2008-01-31) Amidic derivatives of valproic acid, valpromide and valnoctamide, inhibit HSV-1 infection in oligodendrocytes.B Praena et al.Antiviral research, 168, 91-99 (2019-05-28) Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data.Joseph R Calabrese et al.Bipolar disorders, 9(6), 628-635 (2007-09-12) [Pharmacokinetics of biological tags in a case of acute valpromide self poisoning].Diane Commandeur et al.Annales de biologie clinique, 68(2), 234-238 (2010-03-30) Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers.Chun Yang et al.Drug metabolism and disposition: the biological fate of chemicals, 47(2), 104-113 (2018-11-18) Oxetane Substrates of Human Microsomal Epoxide Hydrolase.Francesca Toselli et al.Drug metabolism and disposition: the biological fate of chemicals, 45(8), 966-973 (2017-06-11) Activation of unfolded protein response pathway is important for valproic acid mediated increase in immunoglobulin G productivity in recombinant Chinese hamster ovary cells.Kamal Prashad Segar et al.Journal of bioscience and bioengineering, 124(4), 459-468 (2017-06-12) Valproate decreases inositol biosynthesis.Galit Shaltiel et al.Biological psychiatry, 56(11), 868-874 (2004-12-04) [Valpromide, Valproic acid and removal of small intestine in the treatment of a chronic depression: a case report].G Benjelloun et al.L'Encephale, 30(4), 400-403 (2004-11-13) Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.Zoya Marinova et al.Journal of neurochemistry, 111(4), 976-987 (2009-09-22) Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells.F Condorelli et al.British journal of pharmacology, 153(4), 657-668 (2007-12-07) Delayed toxicity following acute ingestion of valpromide.C Payen et al.Human & experimental toxicology, 23(3), 145-148 (2004-05-04) [Observation on therapeutic effect of acupoint catgut-embedding combined western medicine for epilepsy of generalized seizures type].Zhong-nan Mao et al.Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 31(6), 509-512 (2011-07-12) Adverse effect of valproic acid on an in vitro gastrulation model entails activation of retinoic acid signaling.Aileen S W Li et al.Reproductive toxicology (Elmsford, N.Y.), 66, 68-83 (2016-10-30) The role of histone acetylation in SMN gene expression.Lauren E Kernochan et al.Human molecular genetics, 14(9), 1171-1182 (2005-03-18)

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