Melting point	87-88 ºC**
Density	1.127±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Peer-Reviewed Papers

Processing of human protryptase in mast cells involves cathepsins L, B, and C.Quang T Le et al.Journal of immunology (Baltimore, Md. : 1950), 187(4), 1912-1918 (2011-07-12) Cathepsin C and plasma glutamate carboxypeptidase secreted from Fischer rat thyroid cells liberate thyroxin from the N-terminus of thyroglobulin.Dejan Suban et al.Biochimie, 94(3), 719-726 (2011-12-01) Case of rippled-pattern sebaceoma with clinically yellowish surface and histopathological paucity of lipid-containing neoplastic cells.Yoshio Kawakami et al.The Journal of dermatology, 39(7), 644-646 (2011-11-15) Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.Bin Zhang et al.Blood, 118(12), 3384-3391 (2011-07-29) The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human.Éva Korpos et al.Diabetes, 62(2), 531-542 (2012-11-10) Haim Munk syndrome: report of two siblings of northern India treated with acitretin.Raviprakash Sasankoti Mohan et al.Indian journal of dermatology, venereology and leprology, 77(2), 252-252 (2011-03-12) Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.Brian Ruffell et al.Genes & development, 27(19), 2086-2098 (2013-09-26) Identification of novel mutation in cathepsin C gene causing Papillon-Lefèvre Syndrome in Mexican patients.José G Romero-Quintana et al.BMC medical genetics, 14, 7-7 (2013-01-15) Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.Lee S Jacobson et al.The Journal of biological chemistry, 288(11), 7481-7491 (2013-01-09) THE CATALYTIC PROPERTIES OF CATHEPSIN C.R J PLANTA et al.Biochimica et biophysica acta, 89, 511-519 (1964-09-18) Promiscuous processing of human alphabeta-protryptases by cathepsins L, B, and C.Quang T Le et al.Journal of immunology (Baltimore, Md. : 1950), 186(12), 7136-7143 (2011-05-13) Expression of interleukin-4 receptor α in human corneal epithelial cells.Mayumi Ueta et al.Japanese journal of ophthalmology, 55(4), 405-410 (2011-05-28) Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.R Robert Vethanayagam et al.PloS one, 6(12), e28149-e28149 (2011-12-14) Lysosome-membrane fusion mediated superoxide production in hyperglycaemia-induced endothelial dysfunction.Jun-Xiang Bao et al.PloS one, 7(1), e30387-e30387 (2012-01-19) Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease.Wenli Liu et al.The Journal of clinical investigation, 123(9), 3751-3755 (2013-08-03) The specificity of dipeptidyl aminopeptidase I (cathepsin C) and its use in peptide sequence studies.H Lindley The Biochemical journal, 126(3), 683-685 (1972-02-01) The specificity of dipeptidyl transferase.I M Voynick et al.Biochemistry, 7(1), 40-44 (1968-01-01) NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.Natascha C Perera et al.Journal of immunology (Baltimore, Md. : 1950), 191(5), 2700-2707 (2013-08-02) The novel CTSC homozygous nonsense mutation p.Lys106X in a patient with Papillon-Lefèvre syndrome with all permanent teeth remaining at over 40 years of age.T Kobayashi et al.The British journal of dermatology, 169(4), 948-950 (2013-05-15) Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation.Kai Fan et al.Journal of neuroinflammation, 9, 96-96 (2012-05-23) High immunoglobulin E in a Chinese Papillon-Lefèvre syndrome patient with novel compound mutations of cathepsin C.Xuan Wen et al.The Journal of dermatology, 39(7), 664-665 (2012-01-10) Endopeptidase activity of cathepsin C, dipeptidyl aminopeptidase I, from bovine spleen.M Kuribayashi et al.Journal of biochemistry, 113(4), 441-449 (1993-04-01) Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation.Ellen Melaleuca Menkhorst et al.PloS one, 7(2), e31418-e31418 (2012-02-24) Protein modeling of cathepsin C mutations found in Papillon-Lefèvre syndrome.Morteza Moghaddasian et al.Gene, 538(1), 182-187 (2014-01-01) Vacuolar protein sorting receptor in Giardia lamblia.Maria R Rivero et al.PloS one, 7(8), e43712-e43712 (2012-08-24) Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice.Wenli Liu et al.Journal of immunology (Baltimore, Md. : 1950), 189(5), 2460-2467 (2012-07-31) Cytokine production by leukocytes of Papillon-Lefèvre syndrome patients in whole blood cultures.Christian D Sadik et al.Clinical oral investigations, 16(2), 591-597 (2011-03-08) Role of cathepsin A and cathepsin C in the regulation of glycosidase activity.Alina Minarowska et al.Folia histochemica et cytobiologica, 50(1), 20-24 (2012-04-26) Cathepsin C gene 5'-untranslated region mutation in papillon-lefèvre syndrome.Rok Kosem et al.Dermatology (Basel, Switzerland), 225(3), 193-203 (2012-10-31) Biodegradable thermogels.Min Hee Park et al.Accounts of chemical research, 45(3), 424-433 (2011-10-14) JAAD grand rounds quiz. A 40-year-old man with hyperkeratotic palms and soles. Papillone-Lefèvre syndrome.Joy D Wisniewski et al.Journal of the American Academy of Dermatology, 66(2), 339-341 (2012-01-17) Late stage cathepsin C, CXCL13 and Ki-67 overexpression correlate with regional neuropathology in a BSE transgenic murine model.E Vidal et al.Journal of comparative pathology, 148(1), 22-32 (2012-07-14) Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis.Adrian Schreiber et al.Journal of the American Society of Nephrology : JASN, 23(3), 470-482 (2012-01-14) New observations on the substrate specificity of cathepsin C (dipeptidyl aminopeptidase I). Including the degradation of beta-corticotropin and other peptide hormones.J K McDonald et al.The Journal of biological chemistry, 244(10), 2693-2709 (1969-05-25) Purification and properties of dipeptidyl transferase (Cathepsin C).R M Metroione et al.Biochemistry, 5(5), 1597-1604 (1966-05-01) The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis.Jon K Rubach et al.Biochemistry, 51(38), 7551-7568 (2012-08-30) Involvement of Fenneropenaeus chinensis Cathepsin C in antiviral immunity.Shuai Wang et al.Fish & shellfish immunology, 33(4), 821-828 (2012-08-14) Cathepsin C inhibitors: property optimization and identification of a clinical candidate.Mark Furber et al.Journal of medicinal chemistry, 57(6), 2357-2367 (2014-03-07) Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma.E Wilharm et al.The Journal of biological chemistry, 274(38), 27331-27337 (1999-09-10) NSP4, an elastase-related protease in human neutrophils with arginine specificity.Natascha C Perera et al.Proceedings of the National Academy of Sciences of the United States of America, 109(16), 6229-6234 (2012-04-05) The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C.Hajime Kono et al.Journal of immunology (Baltimore, Md. : 1950), 189(7), 3734-3740 (2012-08-24)

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