
Bafetinib | CAS:859212-16-1
Bafetinib
- Name:Bafetinib
- CAS:859212-16-1
- Synonyms:N-[3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide
- Molecular Formula:C30H31F3N8O
- Molecular Weight:576.62
- EINESC:
Description
Properties
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Safety
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SDS
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Synthetic Route
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Articles
Peer-Reviewed Papers
Quantitative structure-activity relationship study of novel alpha1a-selective adrenoceptor antagonists.P Singh et al.Journal of enzyme inhibition, 16(4), 331-338 (2002-03-28)
QSAR study of 4-phenylpiperidine derivatives as mu opioid agonists by neural network method.Xing-hai Wang et al.European journal of medicinal chemistry, 41(2), 226-232 (2006-01-13)
Structure-activity studies of morphine fragments. I. 4-alkyl-4-(m-hydroxy-phenyl)-piperidines.G H Loew et al.Molecular pharmacology, 34(3), 363-376 (1988-09-01)
Influence of cocaine history on the behavioral effects of Dopamine D(3) receptor-selective compounds in monkeys.B L Blaylock et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(5), 1104-1113 (2011-02-04)
Clandestine drug synthesis.W H Soine Medicinal research reviews, 6(1), 41-74 (1986-01-01)
[Derivatives of 4-phenylpiperidine as substrates of rat brain monoamine oxidase].A G Ishkov et al.Voprosy meditsinskoi khimii, 38(2), 25-28 (1992-03-01)
Pyrrolovesamicols--synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers.Barbara Wenzel et al.Bioorganic & medicinal chemistry letters, 22(6), 2163-2166 (2012-03-01)
Benz[f]isoquinoline analogues as high-affinity sigma ligands.M G Russell et al.Journal of medicinal chemistry, 35(11), 2025-2033 (1992-05-29)
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).Fredrik Pettersson et al.Journal of medicinal chemistry, 53(6), 2510-2520 (2010-02-17)
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.R A Glennon et al.Journal of medicinal chemistry, 34(12), 3360-3365 (1991-12-01)
Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.Diane K Luci et al.Bioorganic & medicinal chemistry letters, 17(23), 6489-6492 (2007-10-16)
A facile synthesis for novel loperamide analogs as potential μ opioid receptor agonists.Xiaofeng Bao et al.Molecules (Basel, Switzerland), 17(12), 14288-14297 (2012-12-05)
Radical-mediated nitrile translocation as the key step in the stereoselective transformation of 2-(4-chloro-2-cyanobutyl)aziridines to methyl cis-(1-arylmethyl-4-phenylpiperidin-2-yl)acetates.Karel Vervisch et al.Organic & biomolecular chemistry, 10(16), 3308-3314 (2012-03-14)
Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists.Paul J Emmerson et al.European journal of pharmacology, 494(2-3), 121-130 (2004-06-24)
A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore.Alan C Spivey et al.Organic & biomolecular chemistry, 6(22), 4093-4095 (2008-10-31)
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