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4-Bromo-5-fluoro-1H-pyridin-2-one | CAS:884495-01-6
4-Bromo-5-fluoro-1H-pyridin-2-one
  • Name:4-Bromo-5-fluoro-1H-pyridin-2-one
  • CAS:884495-01-6
  • Synonyms:4-Bromo-5-fluoro-2(1H)-pyridinone
  • Molecular Formula:C5H3BrFNO
  • Molecular Weight:191.99
  • EINESC:

Description

Properties

Boiling point 231 ºC
Flash point 93 ºC
Density 1.86

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Peer-Reviewed Papers
Clemizole hydrochloride.Parvez M Acta Crystallographica Section C, Structural Chemistry, 52(4), 904-905 (1996) Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.Katarina Ondrusova et al.Scientific reports, 7(1), 16332-16332 (2017-11-29) Critical Components for Spontaneous Activity and Rhythm Generation in Spinal Cord Circuits in Culture.Samuel Buntschu et al.Frontiers in cellular neuroscience, 14, 81-81 (2020-05-16) Clemizole hydrochloride is a novel and potent inhibitor of transient receptor potential channel TRPC5.Julia M Richter et al.Molecular pharmacology, 86(5), 514-521 (2014-08-21) Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.Alberto Arboit et al.Cells, 9(2) (2020-02-09) Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice.Caoimhin S Griffin et al.Scientific reports, 8(1), 9264-9264 (2018-06-20) Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.Scott C Baraban et al.Nature communications, 4, 2410-2410 (2013-09-05)
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