Density	1.756±0.06 g/cm3 (20 º

没有数据	没有数据

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Mucoadhesive beads of gellan gum/pectin intended to controlled delivery of drugs.Fabíola Garavello Prezotti et al.Carbohydrate polymers, 113, 286-295 (2014-09-27) Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep.D Marini et al.Australian veterinary journal, 93(8), 265-270 (2015-07-30) Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug.Sifei Han et al.Pharmaceutical research, 32(5), 1830-1844 (2014-12-03) A case of photoallergic contact dermatitis caused by unusual exposure to ketoprofen.Rossana Conti et al.Dermatitis : contact, atopic, occupational, drug, 23(6), 295-296 (2012-11-22) Topical ketoprofen patch.Bernard Mazières Drugs in R&D, 6(6), 337-344 (2005-11-09) Properties of bioadhesive ketoprofen liquid suppositories: preparation, determination of gelation temperature, viscosity studies and evaluation of mechanical properties using texture analyzer by 4 × 4 factorial design.Işık Ozgüney et al.Pharmaceutical development and technology, 19(8), 968-975 (2013-10-26) Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells.Shinobu Fujii et al.The Journal of pharmacy and pharmacology, 65(2), 171-180 (2013-01-03) Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188.Sarah Maud Fischer et al.The Journal of pharmacy and pharmacology, 64(11), 1631-1637 (2012-10-13) A charged aerosol detector/chemiluminescent nitrogen detector/liquid chromatography/mass spectrometry system for regular and fragment compound analysis in drug discovery.Yutao Jiang et al.Journal of chromatography. A, 1411, 63-68 (2015-08-11) Imaging the Stromal Vascular Fraction during Soft-Tissue Reconstruction.Jacqueline M Bliley et al.Plastic and reconstructive surgery, 136(6), 1205-1215 (2015-11-26) Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I.Ming Liu et al.Bioorganic & medicinal chemistry letters, 21(14), 4243-4247 (2011-06-22) Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan.Gordon C C Yang et al.Journal of hazardous materials, 277, 53-61 (2014-04-08) Inhibition of heat-induced denaturation of albumin by nonsteroidal antiinflammatory drugs (NSAIDs): pharmacological implications.L Saso et al.Archives of pharmacal research, 24(2), 150-158 (2001-05-08) Polyamidoamine dendrimers used as solubility enhancers of ketoprofenYiyun C, et al. European Journal of Medicinal Chemistry, 40(12), 1390-1393 (2005) Non-steroidal anti-inflammatory drugs and gastroprotection with proton pump inhibitors: a focus on ketoprofen/omeprazole.Antonio Gigante et al.Clinical drug investigation, 32(4), 221-233 (2012-02-22) Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.Yan-Ping Duan et al.The Science of the total environment, 447, 267-273 (2013-02-09) Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry.Abdelmonaim Azzouz et al.Food chemistry, 178, 63-69 (2015-02-24) Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.Stanislav Gobec et al.Bioorganic & medicinal chemistry letters, 15(23), 5170-5175 (2005-09-27) Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B.David J Durgan et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(3), 402-411 (2014-11-27) Efficacy of Common Analgesics for Postsurgical Pain in Rats.Megan E Waite et al.Journal of the American Association for Laboratory Animal Science : JAALAS, 54(4), 420-425 (2015-08-01) Selective retention of basic compounds by metal aquo-ion affinity chromatography.Yoshiki Asakawa et al.Journal of separation science, 37(19), 2641-2651 (2014-07-22) Factors influencing the severity of pain during hysterosalpingography.Iwona Szymusik et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 129(2), 118-122 (2015-02-05) In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.Brian J Krieg et al.Journal of pharmaceutical sciences, 103(11), 3473-3490 (2014-09-13) Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release.Zeting Yuan et al.International journal of pharmaceutics, 446(1-2), 191-198 (2013-02-21) A dispersive liquid-liquid micellar microextraction for the determination of pharmaceutical compounds in wastewaters using ultra-high-performace liquid chromatography with DAD detection.Sarah Montesdeoca-Esponda et al.Biomedical chromatography : BMC, 29(3), 353-356 (2014-07-25) 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.Marcello Allegretti et al.Journal of medicinal chemistry, 48(13), 4312-4331 (2005-06-25) Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.Manthena V S Varma et al.Journal of medicinal chemistry, 53(3), 1098-1108 (2010-01-15) Organization of local horizontal functional interactions between neurons in the inferior temporal cortex of macaque monkeys.Hiroshi Tamura et al.Journal of neurophysiology, 111(12), 2589-2602 (2014-03-29) A poly(alkyl methacrylate-divinylbenzene-vinylbenzyl trimethylammonium chloride) monolithic column for solid-phase microextraction.Wan-Ling Liu et al.Journal of chromatography. A, 1395, 32-40 (2015-04-15) Stabilization of Human Serum Albumin against Urea Denaturation by Diazepam and Ketoprofen.Pralad Manoharan et al.Protein and peptide letters, 22(7), 611-617 (2015-05-12) In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.Giorgio Ottaviani et al.Journal of medicinal chemistry, 50(4), 742-748 (2007-02-16) A new and fast strategy based on semiautomatic microextraction by packed sorbent followed by ultra high performance liquid chromatography for the analysis of drugs and their metabolites in human urine.Sylwia Magiera et al.Journal of separation science, 37(22), 3314-3315 (2014-08-28) Innovative sampling and extraction methods for the determination of nonsteroidal anti-inflammatory drugs in water.Shivani Tanwar et al.Journal of pharmaceutical and biomedical analysis, 106, 100-106 (2014-12-01) High-Throughput Raman Spectroscopy Screening of Excipients for the Stabilization of Amorphous Drugs.Xiaoyun Chen et al.Applied spectroscopy, 69(11), 1271-1280 (2015-12-10) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Soy glyceollins regulate transcript abundance in the female mouse brain.Sanaya F Bamji et al.Functional & integrative genomics, 15(5), 549-561 (2015-05-09) Photodegradation kinetics and transformation products of ketoprofen, diclofenac and atenolol in pure water and treated wastewater.R Salgado et al.Journal of hazardous materials, 244-245, 516-527 (2012-11-28) Critical development by design of a rugged HPLC-MS/MS method for direct determination of ibuprofen enantiomers in human plasma.Natalija Nakov et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 992, 67-75 (2015-05-11) Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.Xiaofan Sui et al.European journal of medicinal chemistry, 44(11), 4455-4460 (2009-07-10) Comparison of the effects of preoperative and intraoperative intravenous application of dexketoprofen on postoperative analgesia in septorhinoplasty patients: randomised double blind clinical trial.A B Ozer et al.European review for medical and pharmacological sciences, 16(13), 1828-1833 (2012-12-05) Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.Minggui Yuan et al.Bioorganic & medicinal chemistry, 19(3), 1189-1196 (2011-01-18) Biowaiver monographs for immediate-release solid oral dosage forms: ketoprofen.Igor E Shohin et al.Journal of pharmaceutical sciences, 101(10), 3593-3603 (2012-07-13) UDP-glucuronosyltransferases and clinical drug-drug interactions.Tony K L Kiang et al.Pharmacology & therapeutics, 106(1), 97-132 (2005-03-23) A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers.María Ramos-Payán et al.Analytica chimica acta, 849, 7-11 (2014-10-11) Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study.Grace Carolaine Esquivel Velásquez et al.Journal of oral & facial pain and headache, 28(2), 153-158 (2014-05-14) Agar films containing silver nanoparticles as new supports for electromembrane extraction.Cristina Román Hidalgo et al.Analytical and bioanalytical chemistry, 407(5), 1519-1525 (2014-12-19) Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data.H Bagheri et al.Drug safety, 22(5), 339-349 (2000-06-01) Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.Ariane Rennó Brogliato et al.Shock (Augusta, Ga.), 38(6), 620-629 (2012-11-13) In vitro percutaneous absorption of ketoprofen and testosterone: comparison of pluronic lecithin organogel vs. pentravan cream.Paul A Lehman et al.International journal of pharmaceutical compounding, 16(3), 248-252 (2012-10-12) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.R Scott Obach et al.Drug metabolism and disposition: the biological fate of chemicals, 36(7), 1385-1405 (2008-04-23) Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure.Hanna Kumpulainen et al.Journal of medicinal chemistry, 49(3), 1207-1211 (2006-02-03) Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography.Alexandre Grand-Guillaume Perrenoud et al.Journal of chromatography. A, 1360, 275-287 (2014-08-19) Determination of competitive adsorption isotherm of enantiomers on preparative chromatographic columns using inverse method.Jin Xu et al.Journal of chromatography. A, 1273, 49-56 (2012-12-26) Ultra-high-performance liquid chromatography-Time-of-flight high resolution mass spectrometry to quantify acidic drugs in wastewater.Mercedes Becerra-Herrera et al.Journal of chromatography. A, 1423, 96-103 (2015-11-13) QSAR-based permeability model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 19(8), 2615-2624 (2011-04-05) Singlet oxygen mediated DNA damage induced phototoxicity by ketoprofen resulting in mitochondrial depolarization and lysosomal destabilization.Ratan Singh Ray et al.Toxicology, 314(2-3), 229-237 (2013-10-17) 4 cases of photocontact dermatitis due to ketoprofen.M Sugiura et al.Contact dermatitis, 43(1), 16-19 (2000-07-21) Evaluation of an electrochemical biosensor for uric acid measurement in human whole blood samples.Li-Ting Liao et al.Clinica chimica acta; international journal of clinical chemistry, 436, 72-77 (2014-05-13) A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors.Dima Albals et al.Electrophoresis, 35(19), 2807-2818 (2014-07-02) Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.Loretta Aureli et al.Journal of medicinal chemistry, 48(7), 2469-2479 (2005-04-02) Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes.Norimasa Jinno et al.Xenobiotica; the fate of foreign compounds in biological systems, 44(8), 677-686 (2014-03-01) QSAR study on permeability of hydrophobic compounds with artificial membranes.Masaaki Fujikawa et al.Bioorganic & medicinal chemistry, 15(11), 3756-3767 (2007-04-10) Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis.Marieke Voets et al.Journal of medicinal chemistry, 49(7), 2222-2231 (2006-03-31) Effect of ketoprofen and indomethacin on methotrexate pharmacokinetics in mice plasma and tumor tissues.Yasmine M Elmorsi et al.European journal of drug metabolism and pharmacokinetics, 38(1), 27-32 (2012-11-20) Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).Giulia Caron et al.Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29) Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery.India A Reddy et al.ACS chemical neuroscience, 5(10), 943-951 (2014-07-30) 20 years' experience with ketoprofen.E M Veys Scandinavian journal of rheumatology. Supplement, 90, Suppl 1-Suppl44 (1991-01-01) Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.Elena Dreassi et al.European journal of medicinal chemistry, 44(9), 3712-3717 (2009-05-05) Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.Lei Du-Cuny et al.Bioorganic & medicinal chemistry, 17(19), 6983-6992 (2009-09-08) [Efficacy of ketoprofen lysine salt (artrosilene) in the treatment of nonspecific vertebrogenic pain syndromes in outpatients].E A Trubetskaia et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 113(1), 53-55 (2013-03-27) Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.Thomas H Miller et al.The Science of the total environment, 511, 153-160 (2014-12-30) Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties.Elisabeth Christiansen et al.Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23) Scope of partial least-squares regression applied to the enantiomeric composition determination of ketoprofen from strongly overlapped chromatographic profiles.Juan M Padró et al.Journal of separation science, 38(14), 2423-2430 (2015-05-02) Prediction of drug intestinal absorption by new linear and non-linear QSPR.Alan Talevi et al.European journal of medicinal chemistry, 46(1), 218-228 (2010-11-30) Factors influencing crystal growth rates from undercooled liquids of pharmaceutical compounds.Niraj S Trasi et al.The journal of physical chemistry. B, 118(33), 9974-9982 (2014-07-31) Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices.Doina Macocinschi et al.International journal of biological macromolecules, 52, 32-37 (2012-10-06) In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases.Brian J Krieg et al.Journal of pharmaceutical sciences, 104(9), 2894-2904 (2015-05-20) Efficacy of gastro-retentive forms of ecabet sodium in the treatment of gastric ulcer in rats.Ju-Young Kim et al.Archives of pharmacal research, 37(8), 1053-1062 (2013-11-21) Photosensitivity induced by fibric acid derivatives and its relation to photocontact dermatitis to ketoprofen.G Serrano et al.Journal of the American Academy of Dermatology, 27(2 Pt 1), 204-208 (1992-08-01) Complexation with albumins of chiral aromatic substrates and their chemistry in ground and excited states. Catalytic and chirality recognition properties of the protein in the cases of binaphthol, its photoisomers, and ketoprofen.Akihiko Ouchi et al.Chirality, 14(1), 1-11 (2001-12-19) Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).Jenny M Pedersen et al.Journal of medicinal chemistry, 51(11), 3275-3287 (2008-05-07) Ketoprofen as a photoinitiator for anionic polymerization.Yu-Hsuan Wang et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 14(6), 1120-1126 (2015-04-29) In vitro release of ketoprofen suppositories using the USP basket and the flow-through cell dissolution methods.José Raúl Medina et al.Pakistan journal of pharmaceutical sciences, 27(3), 453-458 (2014-05-09) Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems.Andrea Cerciello et al.Journal of pharmaceutical sciences, 104(10), 3451-3458 (2015-06-20) Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery.Alberto Mazzocchi et al.Homeopathy : the journal of the Faculty of Homeopathy, 101(4), 211-216 (2012-10-24) Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.Hayato Nishida et al.Regulatory toxicology and pharmacology : RTP, 72(3), 578-585 (2015-06-07) Programmable flow-based dynamic sorptive microextraction exploiting an octadecyl chemically modified rotating disk extraction system for the determination of acidic drugs in urine.Valentina Manzo et al.Journal of chromatography. A, 1368, 64-69 (2014-12-03) Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.H Harada et al.Die Pharmazie, 70(10), 678-683 (2015-11-26) In vitro-in vivo evaluation of in situ gelling and thermosensitive ketoprofen liquid suppositories.Işık Ozgüney et al.European journal of drug metabolism and pharmacokinetics, 39(4), 283-291 (2013-10-08) Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study.Marco Pistolozzi et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968, 69-78 (2014-01-30) Molecular characteristics for solid-state limited solubility.Carola M Wassvik et al.Journal of medicinal chemistry, 51(10), 3035-3039 (2008-04-10) Preoperative Local Administration of Morphine as an Add-on Therapy in Patients Undergoing Surgical Removal of an Odontogenic Maxillary Cyst. A Randomized, Double-Blind Pilot Study.Marcin Kolacz et al.Journal of oral & facial pain and headache, 29(4), 378-383 (2015-10-21) Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk.Aleksandar Lolić et al.The Science of the total environment, 508, 240-250 (2014-12-08) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.Francisco J Prado-Prado et al.Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27) Pain and ketoprofen: what is its role in clinical practice?P Sarzi-Puttini et al.Reumatismo, 62(3), 172-188 (2010-11-06) Towards high potential magnetic biocatalysts for on-demand elimination of pharmaceuticals.Vaidyanathan Vinoth Kumar et al.Bioresource technology, 200, 81-89 (2015-10-18) Cheap, suitable, predictable and manageable nanoparticles for drug delivery: quantum dots.Ismail Tuncer Degim et al.Current drug delivery, 10(1), 32-38 (2012-09-25) Periosteal microcirculatory reactions in a zoledronate-induced osteonecrosis model of the jaw in rats.Ágnes Janovszky et al.Clinical oral investigations, 19(6), 1279-1288 (2014-10-30) Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen.Kishor V Nikumbh et al.Drug delivery, 22(4), 509-515 (2013-11-26) Design of alginate-based aerogel for nonsteroidal anti-inflammatory drugs controlled delivery systems using prilling and supercritical-assisted drying.Pasquale Del Gaudio et al.Journal of pharmaceutical sciences, 102(1), 185-194 (2012-11-15) A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats.Lisa J Shientag et al.Journal of the American Association for Laboratory Animal Science : JAALAS, 51(6), 832-841 (2013-01-09) Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.Hannu Kokki Paediatric drugs, 12(5), 313-329 (2010-08-31) Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis.Piercarlo Sarzi-Puttini et al.Clinical and experimental rheumatology, 31(5), 731-738 (2013-05-29) Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane.Jie Yuan et al.Stem cell research & therapy, 6, 217-217 (2015-11-07) In vitro-in vivo evaluation of in situ gelling and thermosensitive ketoprofen liquid suppositories.Işık Ozgüney et al.European journal of drug metabolism and pharmacokinetics, 39(4), 283-291 (2013-10-08) Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.H Harada et al.Die Pharmazie, 70(10), 678-683 (2015-11-26) Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study.Marco Pistolozzi et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968, 69-78 (2014-01-30) Histomorphometric Evaluation of Ridge Preservation With and Without Connective Tissue Graft Over Buccal Plate Using Different Types of Bone Substitute: An Animal Study.Gerardo Mendoza-Azpur et al.Implant dentistry, 24(6), 686-692 (2015-07-24) Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.Hayato Nishida et al.Regulatory toxicology and pharmacology : RTP, 72(3), 578-585 (2015-06-07) Programmable flow-based dynamic sorptive microextraction exploiting an octadecyl chemically modified rotating disk extraction system for the determination of acidic drugs in urine.Valentina Manzo et al.Journal of chromatography. A, 1368, 64-69 (2014-12-03) First-principle, structure-based prediction of hepatic metabolic clearance values in human.Haiyan Li et al.European journal of medicinal chemistry, 44(4), 1600-1606 (2008-09-05) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1).Emmanuel Bey et al.Journal of medicinal chemistry, 51(21), 6725-6739 (2008-10-16) Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.Mojca Brunskole et al.Bioorganic & medicinal chemistry, 16(11), 5881-5889 (2008-05-17) MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase.John H Anneken et al.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 8(1), 58-65 (2012-11-28) [Complex therapy of acute and chronic back pain with dexalgin].A E Barulin et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 112(11), 61-64 (2012-12-22) A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry.Cheong Hoon Lee et al.Talanta, 129, 552-559 (2014-08-17) Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox.Lizelle T Fox et al.The Journal of pharmacy and pharmacology, 67(1), 96-106 (2014-09-10) How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?Alex Avdeef et al.Journal of medicinal chemistry, 53(9), 3566-3584 (2010-04-09) Pain and ketoprofen: what is its role in clinical practice?P Sarzi-Puttini et al.Reumatismo, 62(3), 172-188 (2010-11-06) Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk.Aleksandar Lolić et al.The Science of the total environment, 508, 240-250 (2014-12-08) Towards high potential magnetic biocatalysts for on-demand elimination of pharmaceuticals.Vaidyanathan Vinoth Kumar et al.Bioresource technology, 200, 81-89 (2015-10-18) Periosteal microcirculatory reactions in a zoledronate-induced osteonecrosis model of the jaw in rats.Ágnes Janovszky et al.Clinical oral investigations, 19(6), 1279-1288 (2014-10-30) Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.Francisco J Prado-Prado et al.Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27) Cheap, suitable, predictable and manageable nanoparticles for drug delivery: quantum dots.Ismail Tuncer Degim et al.Current drug delivery, 10(1), 32-38 (2012-09-25) Effect of phonophoresis on skin permeation of commercial anti-inflammatory gels: sodium diclofenac and ketoprofen.Jaqueline Souza et al.Ultrasound in medicine & biology, 39(9), 1623-1630 (2013-07-04) Ketoprofen 2.5% gel: a clinical overview.S Coaccioli European review for medical and pharmacological sciences, 15(8), 943-949 (2011-08-19) Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway.Nam Hyeon Kang et al.Pflugers Archiv : European journal of physiology, 472(5), 583-596 (2020-05-03) Ketoprofen allergic reactions.Carmen Cantisani et al.Recent patents on inflammation & allergy drug discovery, 4(1), 58-64 (2009-10-17) Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.Hannu Kokki Paediatric drugs, 12(5), 313-329 (2010-08-31) Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen.Kishor V Nikumbh et al.Drug delivery, 22(4), 509-515 (2013-11-26) Salt-induced sympathoexcitation involves vasopressin V1a receptor activation in the paraventricular nucleus of the hypothalamus.Natalia Ribeiro et al.American journal of physiology. Regulatory, integrative and comparative physiology, 309(11), R1369-R1379 (2015-09-12) In vitro chiral conversion, phase separation, and wave propagation in aged profen solutionsSajewicz M, et al. Journal of Liquid Chromatography and Related Technologies, 32(9), 1359-1372 (2009) The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum.Nathalie C Newby et al.Journal of dairy science, 96(3), 1511-1520 (2013-01-22) Neural computational prediction of oral drug absorption based on CODES 2D descriptors.A Guerra et al.European journal of medicinal chemistry, 45(3), 930-940 (2009-12-22) Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox.Lizelle T Fox et al.The Journal of pharmacy and pharmacology, 67(1), 96-106 (2014-09-10) Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.Gustav Ahlin et al.Journal of medicinal chemistry, 51(19), 5932-5942 (2008-09-16) Resolution of enantiomers of ketoprofen by HPLC: a review.Ramesh Mullangi et al.Biomedical chromatography : BMC, 17(7), 423-434 (2003-11-05) Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.Bram Baert et al.Bioorganic & medicinal chemistry, 15(22), 6943-6955 (2007-09-11) A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry.Cheong Hoon Lee et al.Talanta, 129, 552-559 (2014-08-17) Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats.Magdalena Gaweł et al.Pharmacological reports : PR, 66(5), 862-866 (2014-08-26) Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting.Julia Martín et al.The Science of the total environment, 503-504, 97-104 (2014-06-10) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) [Treatment of back pain (ketoprofen and other methods)].I V Damulin Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 114(2), 81-86 (2014-04-15) Degradation of PPCPs in activated sludge from different WWTPs in Denmark.Xijuan Chen et al.Ecotoxicology (London, England), 24(10), 2073-2080 (2015-09-27) MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase.John H Anneken et al.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 8(1), 58-65 (2012-11-28) Fabrication of mesoporous silica shells on solid silica spheres using anionic surfactants and their potential application in controlling drug release.Ahmed Mohamed El-Toni et al.Molecules (Basel, Switzerland), 17(11), 13199-13210 (2012-11-08) Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China.Mei-Quan Cai et al.Environmental science and pollution research international, 22(3), 1854-1867 (2014-09-10) Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.Mojca Brunskole et al.Bioorganic & medicinal chemistry, 16(11), 5881-5889 (2008-05-17) Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine.Yun Li et al.Journal of chromatography. A, 1392, 28-36 (2015-03-22) Experimental and computational studies of physicochemical properties influence NSAID-cyclodextrin complexation.Linda A Felton et al.AAPS PharmSciTech, 15(4), 872-881 (2014-04-11) Degradation of PPCPs in activated sludge from different WWTPs in Denmark.Xijuan Chen et al.Ecotoxicology (London, England), 24(10), 2073-2080 (2015-09-27) Neural computational prediction of oral drug absorption based on CODES 2D descriptors.A Guerra et al.European journal of medicinal chemistry, 45(3), 930-940 (2009-12-22) The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum.Nathalie C Newby et al.Journal of dairy science, 96(3), 1511-1520 (2013-01-22) Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.Pil H Lee et al.Bioorganic & medicinal chemistry letters, 20(1), 69-73 (2009-12-08) Time-resolved spectroscopic study of the photochemistry of tiaprofenic acid in a neutral phosphate buffered aqueous solution from femtoseconds to final products.Tao Su et al.The journal of physical chemistry. B, 117(3), 811-824 (2012-12-13) [Perioperative management based on kinetics of bleeding during total primary arthroplasty].E Irisson et al.Annales francaises d'anesthesie et de reanimation, 32(3), 170-174 (2013-01-22) [Treatment of back pain (ketoprofen and other methods)].I V Damulin Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 114(2), 81-86 (2014-04-15) Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.Gustav Ahlin et al.Journal of medicinal chemistry, 51(19), 5932-5942 (2008-09-16) Resolution of enantiomers of ketoprofen by HPLC: a review.Ramesh Mullangi et al.Biomedical chromatography : BMC, 17(7), 423-434 (2003-11-05) Exploring the interaction between the antiallergic drug, tranilast and human serum albumin: Insights from calorimetric, spectroscopic and modeling studies.Saad Tayyab et al.International journal of pharmaceutics, 491(1-2), 352-358 (2015-07-05) Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.Giorgio Ottaviani et al.Journal of medicinal chemistry, 49(13), 3948-3954 (2006-06-23) New NSAIDs-NO hybrid molecules with antiproliferative properties on human prostatic cancer cell lines.Nicolas Bézière et al.Bioorganic & medicinal chemistry letters, 18(16), 4655-4657 (2008-08-01) Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater.Paula Paíga et al.Journal of pharmaceutical and biomedical analysis, 106, 61-70 (2014-07-09) A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthritis.Philip G Conaghan et al.Rheumatology (Oxford, England), 52(7), 1303-1312 (2013-04-02) Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.Yusuf Tunali et al.Journal of neurosurgical anesthesiology, 25(2), 143-147 (2013-01-31) A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.David Buttar et al.Bioorganic & medicinal chemistry, 18(21), 7486-7496 (2010-09-28) Physicochemical determinants of human renal clearance.Manthena V S Varma et al.Journal of medicinal chemistry, 52(15), 4844-4852 (2009-05-19) Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment.Anwar Dawas-Massalha et al.Bioresource technology, 167, 336-342 (2014-07-06) The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption.Laura J Waters et al.Journal of pharmaceutical sciences, 105(12), 3611-3614 (2016-10-26) Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.Ninitha Asirvatham-Jeyaraj et al.American journal of physiology. Heart and circulatory physiology, 305(10), H1462-H1470 (2013-09-10) Determination of pharmaceuticals in bivalves using QuEChERS extraction and liquid chromatography-tandem mass spectrometry.Mireia Núñez et al.Analytical and bioanalytical chemistry, 407(13), 3841-3849 (2015-03-18) Acute exercise increases insulin sensitivity in adult sheep: a new preclinical model.Glenn K McConell et al.American journal of physiology. Regulatory, integrative and comparative physiology, 308(6), R500-R506 (2015-01-09) Bar adsorptive microextraction coated with multi-walled carbon nanotube phases - Application for trace analysis of pharmaceuticals in environmental waters.F Abujaber et al.Journal of chromatography. A, 1600, 17-22 (2019-04-22) Multiresidue determination of ten nonsteroidal anti-inflammatory drugs in bovine, porcine, and chicken liver tissues by HPLC-MS/MS.JeongWoo Kang et al.Applied biochemistry and biotechnology, 174(1), 1-5 (2014-07-30) Application of capillary electrophoresis with electrokinetic supercharging and sweeping for the on-line preconcentration of phenolic acids.Yi-Hui Lin et al.Analytical and bioanalytical chemistry, 407(23), 7093-7100 (2015-07-15) Effects of non-enzymatic glycation in human serum albumin. Spectroscopic analysis.A Szkudlarek et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 152, 645-653 (2015-03-05) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase.Dina S Shokry et al.Biomedical chromatography : BMC, 33(7), e4515-e4515 (2019-02-28) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) [Perioperative management based on kinetics of bleeding during total primary arthroplasty].E Irisson et al.Annales francaises d'anesthesie et de reanimation, 32(3), 170-174 (2013-01-22) Ketoprofen extended-release capsules: a new formulation for the treatment of osteoarthritis and rheumatoid arthritis.H R Schumacher Clinical therapeutics, 16(2), 145-159 (1994-03-01)

Remarks