Density	1.42±0.1 g/cm3 (20 ºC

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

The antiproliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway.Yan-Lin Wei et al.Anatomical record (Hoboken, N.J. : 2007), 292(7), 945-950 (2009-06-24) Interaction of cepharanthine with immobilized heat shock protein 90α (Hsp90α) and screening of Hsp90α inhibitors.Jun Haginaka et al.Analytical biochemistry, 434(1), 202-206 (2012-12-12) Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.Yiping Ren et al.Journal of immunology (Baltimore, Md. : 1950), 181(2), 1491-1498 (2008-07-09) Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice.Guan-Yu Wang et al.Journal of Asian natural products research, 11(3), 219-228 (2009-05-02) Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-mediated pathway.Xiao-ying Zhao et al.Chinese medical journal, 120(9), 802-806 (2007-05-29) [Mechanism related to inhibition of leukemia K562 cells by berbamine].Yan-lin WEI et al.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 38(4), 387-391 (2009-08-21) Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.Sangkil Nam et al.Molecular oncology, 6(5), 484-493 (2012-06-22) Synthesis of berbamine acetyl glycosides and evaluation of antitumor activity.Yanli Cui et al.European journal of medicinal chemistry, 54, 867-872 (2012-05-29) Berbamine overcomes imatinib-induced neutropenia and permits cytogenetic responses in Chinese patients with chronic-phase chronic myeloid leukemia.Yanmin Zhao et al.International journal of hematology, 94(2), 156-162 (2011-07-06) CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine.Ying Gu et al.Blood, 120(24), 4829-4839 (2012-10-18) Berbamine induces apoptosis in human hepatoma cell line SMMC7721 by loss in mitochondrial transmembrane potential and caspase activation.Guan-yu Wang et al.Journal of Zhejiang University. Science. B, 8(4), 248-255 (2007-04-21) Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.Shan Wang et al.Molecular cancer, 8, 81-81 (2009-10-03) Probing the binding sites and the effect of berbamine on the structure of bovine serum albumin.Xiao-Xia Cheng et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(5), 922-928 (2009-02-03) Berbamine protects the heart from ischemia/reperfusion injury by maintaining cytosolic Ca(2+) homeostasis and preventing calpain activation.Cai-Mei Zhang et al.Circulation journal : official journal of the Japanese Circulation Society, 76(8), 1993-2002 (2012-06-06) The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids.Xiaohui Ji et al.Nucleic acid therapeutics, 21(6), 415-422 (2011-10-25) Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells.Yun Liang et al.Acta pharmacologica Sinica, 30(12), 1659-1665 (2009-12-05) Delivery of paclitaxel and berbamine by polymeric carriers to cure gastric cancer.Lingjun Zhu et al.Oncology research, 20(7), 265-274 (2013-07-25) Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo.Yan-lin Wei et al.Acta pharmacologica Sinica, 30(4), 451-457 (2009-03-10) Flavonols, alkaloids, and antioxidant capacity of edible wild berberis species from patagonia.Antonieta Ruiz et al.Journal of agricultural and food chemistry, 62(51), 12407-12417 (2014-12-17) Studies on alkaloids binding to GC-rich human survivin promoter DNA using positive and negative ion electrospray ionization mass spectrometry.Zhaofu Wang et al.Journal of mass spectrometry : JMS, 43(3), 327-335 (2007-10-31) Berbamine increases myocardial contractility via a Ca2+-independent mechanism.Cai-Mei Zhang et al.Journal of cardiovascular pharmacology, 58(1), 40-48 (2011-07-15) A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells.Rong Liu et al.Journal of pharmaceutical sciences, 99(7), 3266-3275 (2010-01-30) [Berbamine induces apoptosis of multiple myeloma RPMI 8226 cells by activating GADD45/JNK pathway].Yun Liang et al.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 38(5), 439-444 (2009-10-16) Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity.Yun Liang et al.Journal of Zhejiang University. Science. B, 12(7), 568-574 (2011-07-05) [The mechanism of apoptosis of chronic myeloid leukemia cells induced by the novel p210 bcr/abl inhibitor berbamine].Jian-rong Sun et al.Zhonghua yi xue za zhi, 86(32), 2246-2251 (2006-10-27)

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