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4-Chloro-3-fluorobenzeneacetic acid ethyl ester | CAS:1256479-12-5
4-Chloro-3-fluorobenzeneacetic acid ethyl ester
  • Name:4-Chloro-3-fluorobenzeneacetic acid ethyl ester
  • CAS:1256479-12-5
  • Synonyms:(4-Chloro-3-fluorophenyl)acetic acid ethyl ester
  • Molecular Formula:C10H10ClFO2
  • Molecular Weight:216.64
  • EINESC:

Description

Properties

Boiling point 258.8±25.0 ºC (760 Tor
Flash point 99.1±12.3 ºC, 计算值*
Density 1.238±0.06 g/cm3 (20 º

Safety

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SDS

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Articles
Peer-Reviewed Papers
Chlorhexidine gluconate-impregnated central-line dressings and necrosis in complicated skin disorder patients.Jennifer B Wall et al.Journal of critical care, 29(6), 1130-1130 (2014-07-19) [Preoperative chlorhexidine shower--unscientific advice from the Swedish Association of Local Authorities and Regions].Christer Drott Lakartidningen, 110(16), 836-836 (2013-05-31) Cytogenetic analysis of oral mucosa cells, induced by chlorhexidine, essential oils in ethanolic solution and triclosan mouthwashes.Irene Ros-Llor et al.Environmental research, 132, 140-145 (2014-04-29) The impact of topical corticosteroid use before diagnosis on the outcome of Acanthamoeba keratitis.Dana Robaei et al.Ophthalmology, 121(7), 1383-1388 (2014-03-19) Decreased susceptibility to chlorhexidine and prevalence of disinfectant resistance genes among clinical isolates of Staphylococcus epidermidis.Gustaf Prag et al.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 122(10), 961-967 (2014-03-19) Daily chlorhexidine bathing for critically ill patients: a note of caution.Didier Pittet et al.JAMA, 313(4), 365-366 (2015-01-21) Preoperative chlorhexidine anaphylaxis in a patient scheduled for coronary artery bypass graft: a case report.Matthew Toomey AANA journal, 81(3), 209-214 (2013-08-09) Influence of peripheral enamel bonding and chlorhexidine pretreatment on resin bonding to dentin.Jun Lin et al.The journal of adhesive dentistry, 15(4), 351-359 (2013-04-18) Single-dose intra-alveolar chlorhexidine gel application, easier surgeries, and younger ages are associated with reduced dry socket risk.Afshin Haraji et al.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(2), 259-265 (2014-01-21) Effects of intra-alveolar placement of 0.2% chlorhexidine bioadhesive gel on dry socket incidence and postsurgical pain: a double-blind split-mouth randomized controlled clinical trial.Afshin Haraji et al.Journal of orofacial pain, 27(3), 256-262 (2013-07-25) Chlorhexidine droplet splash from a skin preparation gallipot: effect of height of pouring.L Evans et al.Anaesthesia, 68(12), 1243-1246 (2013-10-12) A suitable device for cystic lesions close to the tooth-bearing areas of the jaws.Fábio Wildson Gurgel Costa et al.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(1), 96-98 (2013-09-03) Chlorhexidine-impregnated dressing: an efficient weapon against catheter-related bloodstream infection?*.Yazine Mahjoub et al.Critical care medicine, 42(7), 1742-1743 (2014-06-17) Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial.Lennie P G Derde et al.The Lancet. Infectious diseases, 14(1), 31-39 (2013-10-29) Survey on oral hygiene measures for intubated patients in Swiss intensive care units.Claudius Gmür et al.Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 123(5), 394-409 (2013-05-31) Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection.Arne Ohlsson et al.The Cochrane database of systematic reviews, 12(12), CD003520-CD003520 (2014-12-17) Chitosan based nanoparticles functionalized with peptidomimetic derivatives for oral drug delivery.Laura Chronopoulou et al.New biotechnology, 33(1), 23-31 (2015-08-11) Effectiveness of standard lavage with supplemental chlorhexidine in patients undergoing chemical matricectomy for ingrown toenails: a clinical trial.Damian Cordoba-Diaz et al.Journal of the American Academy of Dermatology, 70(6), 1092-1095 (2014-04-01) Oral antibiotics versus topical decolonization to prevent surgical site infection after Mohs micrographic surgery--a randomized, controlled trial.Paul Cherian et al.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(10), 1486-1493 (2013-10-05) Keratocystic odontogenic tumor. Case report and review of the literature.Mariano Sanchez-Siles et al.The New York state dental journal, 79(2), 44-47 (2013-05-23) Implant abutment screw reverse torque values before and after plasma cleaning.Costanza Micarelli et al.The International journal of prosthodontics, 26(4), 331-333 (2013-07-10) Superficial roughness on composite surface, composite enamel and composite dentin junctions after different finishing and polishing procedures. Part I: roughness after treatments with tungsten carbide vs diamond burs.Federico Ferraris et al.The international journal of esthetic dentistry, 9(1), 70-89 (2014-04-24) Development of a practical complete-kill assay to evaluate anti-Acanthamoeba drugs.Regis P Kowalski et al.JAMA ophthalmology, 131(11), 1459-1462 (2013-10-01) Targeted versus universal decolonization to prevent ICU infection.Susan S Huang et al.The New England journal of medicine, 368(24), 2255-2265 (2013-05-31) Antiseptic use in Mohs and reconstructive surgery: an American College of Mohs Surgery member survey.Lindsey K Collins et al.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 41(1), 164-166 (2014-12-19) Cytotoxicity and genotoxicity of chlorhexidine on macrophages in vitro.Yi-Ching Li et al.Environmental toxicology, 29(4), 452-458 (2012-04-11) Care bundles in intensive care units - authors' reply.Marc J M Bonten et al.The Lancet. Infectious diseases, 14(5), 372-372 (2014-04-25) Data bits: take a swipe at surgical site infections.Janet Bertoli et al.Kentucky nurse, 62(2), 3-3 (2014-05-06) Effect of chlorhexidine varnish application on streptoococcus mutans colonisation in adolescents with fixed orthodontic appliances.Rengin Attin et al.Australian orthodontic journal, 29(1), 52-57 (2013-06-22) Recently introduced qacA/B genes in Staphylococcus epidermidis do not increase chlorhexidine MIC/MBC.Sissel Skovgaard et al.The Journal of antimicrobial chemotherapy, 68(10), 2226-2233 (2013-06-07) Antibacterial efficacy and effect of chlorhexidine mixed with irreversible hydrocolloid for dental impressions: a randomized controlled trial.Glória Cubas et al.The International journal of prosthodontics, 27(4), 363-365 (2014-07-11) Propolis and commonly used intracanal irrigants: comparative evaluation of antimicrobial potential.M Jolly et al.The Journal of clinical pediatric dentistry, 37(3), 243-249 (2013-07-17) [Subcutaneous implantation type central venous port management in patients with malignant tumors effect of different antiseptic agents on central venous port-related infection].Junya Sato et al.Gan to kagaku ryoho. Cancer & chemotherapy, 41(8), 981-985 (2014-08-19) Anaphylactic reaction to intraurethral chlorhexidine: sensitisation following previous repeated uneventful administration.J E Dyer et al.Annals of the Royal College of Surgeons of England, 95(6), e105-e106 (2013-09-13) Evaluation of preventive programs in high caries active preschool children.Anna Lena Sundell et al.Swedish dental journal, 37(1), 23-29 (2013-06-01) Inhibition of biofilm formation and antibacterial properties of a silver nano-coating on human dentine.Alexandros Besinis et al.Nanotoxicology, 8(7), 745-754 (2013-07-24) Staphylococcus aureus bacteraemia associated with peripherally inserted central catheters: the role of chlorhexidine gluconate-impregnated sponge dressings.Michael J Loftus et al.The Medical journal of Australia, 200(6), 317-318 (2014-04-08) Ex vivo microbial leakage after using different final irrigation regimens with chlorhexidine.Esther Navarro-Escobar et al.Journal of applied oral science : revista FOB, 21(1), 74-79 (2013-04-06) Chlorhexidine gluconate–impregnated central access catheter dressings as a cause of erosive contact dermatitis: a report of 7 cases.Nicole A Weitz et al.JAMA dermatology, 149(2), 195-199 (2013-04-06) Chlorhexidine bathing and health care-associated infections: a randomized clinical trial.Michael J Noto et al.JAMA, 313(4), 369-378 (2015-01-21) Third-degree chemical burns from chlorhexidine local antisepsis.Ezequiel Palmanovich et al.The Israel Medical Association journal : IMAJ, 15(6), 323-324 (2013-07-26) Novel antiseptic compound OPB-2045G shows potent bactericidal activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus both in vitro and in vivo: a pilot study in animals.Yasuhide Inoue et al.Journal of medical microbiology, 64(Pt 1), 32-36 (2014-10-30) Assessment of implementation of a CAMBRA-based program in a dental school environment.Sorin T Teich et al.Journal of dental education, 77(4), 438-447 (2013-04-12) Rheological properties of gamma-irradiated antimicrobial wafers and in vitro efficacy against Pseudomonas aeruginosa.Olga Labovitiadi et al.International journal of pharmaceutics, 453(2), 462-472 (2013-06-25) Yes, what about prions?A Kirkwood et al.Anaesthesia, 68(10), 1073-1074 (2013-09-21) Incorporation of chlorhexidine gluconate or diacetate into a glass-ionomer cement: porosity, surface roughness, and anti-biofilm activity.Luana Mafra Marti et al.American journal of dentistry, 27(6), 318-322 (2015-02-25) Determining the minimum inhibitory concentration of Tetraclean against Candida albicans.A Qyasian et al.Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria, 23(3), 201-206 (2014-09-05) Antimicrobial resistance in intensive care units.Jean-Ralph Zahar et al.The Lancet. Infectious diseases, 14(1), 3-5 (2013-10-29) Managing an extreme peri-implantitis.A Materni Minerva stomatologica, 62(9), 295-305 (2013-10-16) Does an oral care protocol reduce VAP in patients with a tracheostomy?Patricia Conley et al.Nursing, 43(7), 18-23 (2013-06-20) Daily chlorhexidine bathing and hospital-acquired infection.Jean-Jacques Parienti et al.The New England journal of medicine, 368(24), 2331-2331 (2013-06-14) Daily chlorhexidine bathing and hospital-acquired infection.Anthony L Esposito The New England journal of medicine, 368(24), 2330-2330 (2013-06-14) [Prevention of catheter-related septicemia].S Lemmen et al.Deutsche medizinische Wochenschrift (1946), 139(14), 693-695 (2014-03-29) Effect of chlorhexidine on the 18-month clinical performance of two adhesives.Maristela Dutra-Correa et al.The journal of adhesive dentistry, 15(3), 287-292 (2013-04-06) Influence of mounthrinse solutions on the color stability and microhardness of a composite resin.Cesar Penazzo Lepri et al.The international journal of esthetic dentistry, 9(2), 238-246 (2014-04-26) Evaluation of the in vitro activity of commercially available moxifloxacin and voriconazole eye-drops against clinical strains of Acanthamoeba.C M Martín-Navarro et al.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(9), 2111-2117 (2013-05-21) Screening for MRSA and isolating carriers doesn't reduce ICU infections. BMJ (Clinical research ed.), 346, f3581-f3581 (2013-06-06) Alcohol plus chlorhexidine is more efficient than alcohol alone for phenol-based chemical matricectomy: an in vitro study.Damian Cordoba Diaz et al.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(9), 1363-1367 (2013-05-04) TGF-β1 promotes lymphangiogenesis during peritoneal fibrosis.Hiroshi Kinashi et al.Journal of the American Society of Nephrology : JASN, 24(10), 1627-1642 (2013-08-31) Daily chlorhexidine bathing and hospital-acquired infection.Michael W Climo et al.The New England journal of medicine, 368(24), 2332-2332 (2013-06-14) Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience.Christophe Camus et al.Critical care medicine, 42(5), 1121-1130 (2013-12-25) Chlorhexidine for the prevention of bloodstream infection associated with totally implantable venous ports in patients with solid cancers.Hsiang-Fong Kao et al.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(5), 1189-1197 (2014-01-05) Jaw lesion and discomfort.Liran Levin et al.JAMA, 310(20), 2195-2196 (2013-11-28) Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis.Michael Klompas et al.JAMA internal medicine, 174(5), 751-761 (2014-03-26) Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections.Leighann Sherry et al.BMC oral health, 13, 47-47 (2013-09-26) Effect of oral care solutions in reducing ventilator-associated pneumonia: review of current evidence.E Balamurugan et al.The Nursing journal of India, 103(6), 282-284 (2013-08-09) Chlorhexidine-based oral care and ventilator-associated pneumonia: the devil in disguise?Marc J M Bonten JAMA internal medicine, 174(5), 761-762 (2014-03-26) Chlorhexidine-impregnated dressing for prevention of catheter-related bloodstream infection: a meta-analysis*.Nasia Safdar et al.Critical care medicine, 42(7), 1703-1713 (2014-03-29) A prospective clinical evaluation of the longevity of resorbable sutures in oral surgical procedures.B Fomete et al.Nigerian journal of clinical practice, 16(3), 334-338 (2013-06-19) The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial.Steven P Engebretson et al.JAMA, 310(23), 2523-2532 (2013-12-19) Catheter lubrication and fixation: interventions.Mary Wilson British journal of nursing (Mark Allen Publishing), 22(10), 566-566 (2013-06-12) Antibacterial dental composites with chlorhexidine and mesoporous silica.J F Zhang et al.Journal of dental research, 93(12), 1283-1289 (2014-10-17) A preoperative approach to postoperative infections?Christopher J Arpey Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(10), 1494-1495 (2013-10-05) Care bundles in intensive care units.Samad E J Golzari et al.The Lancet. Infectious diseases, 14(5), 371-372 (2014-04-25) Discussion: does the use of biopatch devices at drain sites reduce perioperative infectious complications in patients undergoing immediate tissue expander breast reconstruction?Deana Saleh Shenaq et al.Plastic and reconstructive surgery, 135(1), 18e-19e (2014-12-30) Does the use of biopatch devices at drain sites reduce perioperative infectious complications in patients undergoing immediate tissue expander breast reconstruction?Katie E Weichman et al.Plastic and reconstructive surgery, 135(1), 9e-17e (2014-12-30) Antimicrobial activity of the essential oil of Tetradenia riparia (Hochst.) Codd. (Lamiaceae) against cariogenic bacteria.Nathalya Isabel de Melo et al.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(2), 519-525 (2015-08-15) CORR Insights®: no infection reduction using chlorhexidine wipes in total joint arthroplasty.Craig J Della Valle Clinical orthopaedics and related research, 471(10), 3126-3127 (2013-07-13) Committee Opinion No. 571: Solutions for surgical preparation of the vagina. Obstetrics and gynecology, 122(3), 718-720 (2013-08-22) Cement-associated signs of inflammation: retrospective analysis of the effect of excess cement on peri-implant tissue.Michael Korsch et al.The International journal of prosthodontics, 28(1), 11-18 (2015-01-15) Commentary: Alcohol plus chlorhexidine is more efficient than alcohol alone for phenol-based chemical matricectomy: in vitro study.Glaysson T Tavares Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(9), 1368-1369 (2013-09-17) Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins.Karl A Hassan et al.Proceedings of the National Academy of Sciences of the United States of America, 110(50), 20254-20259 (2013-11-28) Effect of irrigation with Tetraclean on bacterial leakage of obturated root canals.Zahed Mohammadi et al.The New York state dental journal, 80(3), 39-43 (2014-06-18) Effects of food colouring added to 2% chlorhexidine gluconate and 70% alcohol for surgical site antisepsis.Jason Chow et al.Journal of perioperative practice, 23(11), 255-257 (2013-12-10)
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