Density	1.228±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Peer-Reviewed Papers

[Studies on chemical constituents of rhizome of Matteuccia struthiopteris].Dong Zhang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(14), 1703-1705 (2008-10-10) Pinosylvin suppresses LPS-stimulated inducible nitric oxide synthase expression via the MyD88-independent, but TRIF-dependent downregulation of IRF-3 signaling pathway in mouse macrophage cells.Eun-Jung Park et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(3-4), 353-362 (2011-04-08) IL-6 in Osteoarthritis: Effects of Pine Stilbenoids.Mirka Laavola et al.Molecules (Basel, Switzerland), 24(1) (2019-01-02) Involvement of caspase-3 in stilbene derivatives induced apoptosis of human neutrophils in vitro.Tomáš Perečko et al.Interdisciplinary toxicology, 5(2), 76-80 (2012-11-03) Modulation of TRP channels by resveratrol and other stilbenoids.Lina Yu et al.Molecular pain, 9, 3-3 (2013-02-19) Determination and assay validation of pinosylvin in rat serum: application to drug metabolism and pharmacokinetics.Kathryn Roupe et al.Journal of pharmaceutical and biomedical analysis, 38(1), 148-154 (2005-05-24) [Synthesis and HIV-1 inhibitory activity of natural products isolated from Gnetum parvifolium and their analogues].Zhi-song Piao et al.Yao xue xue bao = Acta pharmaceutica Sinica, 45(12), 1509-1515 (2011-03-01) Molecular cloning and functional characterization of an O-methyltransferase catalyzing 4'-O-methylation of resveratrol in Acorus calamus.Takao Koeduka et al.Journal of bioscience and bioengineering, 127(5), 539-543 (2018-11-26) Isolation and identification of cytotoxic compounds from the wood of Pinus resinosa.François Simard et al.Phytotherapy research : PTR, 22(7), 919-922 (2008-04-05) Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats.Kathryn A Roupe et al.The Journal of pharmacy and pharmacology, 58(11), 1443-1450 (2006-11-30) Suppression of Src/ERK and GSK-3/β-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.Eun-Jung Park et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 55, 424-433 (2013-01-22) Pinosylvin and monomethylpinosylvin, constituents of an extract from the knot of Pinus sylvestris, reduce inflammatory gene expression and inflammatory responses in vivo.Mirka Laavola et al.Journal of agricultural and food chemistry, 63(13), 3445-3453 (2015-03-13) Complexation of pinosylvin, an analogue of resveratrol with high antifungal and antimicrobial activity, by different types of cyclodextrins.José Manuel López-Nicolás et al.Journal of agricultural and food chemistry, 57(21), 10175-10180 (2009-10-10) Wounding response in xylem of Scots pine seedlings shows wide genetic variation and connection with the constitutive defence of heartwood.Anni M Harju et al.Tree physiology, 29(1), 19-25 (2009-02-11) Antibacterial and antifungal activity of pinosylvin, a constituent of pine.S K Lee et al.Fitoterapia, 76(2), 258-260 (2005-03-09) Determination of trans-resveratrol and its metabolites in rat serum using liquid chromatography with high-resolution time of flight mass spectrometry.Jana Rousova et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1039, 35-43 (2016-11-08) Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.Tomas Perecko et al.Neuro endocrinology letters, 29(5), 802-805 (2008-11-07) A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway.Tianhong Yang et al.Plant physiology, 171(4), 2483-2498 (2016-07-01) Vibrational spectroscopy of resveratrol.Ferenc Billes et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 68(3), 669-679 (2007-04-10) Antimetastatic activity of pinosylvin, a natural stilbenoid, is associated with the suppression of matrix metalloproteinases.Eun-Jung Park et al.The Journal of nutritional biochemistry, 23(8), 946-952 (2011-09-23) Formation of reactive oxygen and nitrogen species in the presence of pinosylvin - an analogue of resveratrol.Viera Jancinova et al.Neuro endocrinology letters, 31 Suppl 2, 79-83 (2010-12-29) Polyphenols as resistance modulators in Arcobacter butzleri.Vanessa Sousa et al.Folia microbiologica, 64(4), 547-554 (2019-01-15) Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells.Shalem Modi et al.Scientific reports, 7(1), 17606-17606 (2017-12-16) Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae).C F Massaro et al.Fitoterapia, 95, 247-257 (2014-04-08) Antibacterial effects of knotwood extractives on paper mill bacteria.L E Lindberg et al.Journal of industrial microbiology & biotechnology, 31(3), 137-147 (2004-04-28) Pinosylvin at a high concentration induces AMPK-mediated autophagy for preventing necrosis in bovine aortic endothelial cells.Jinsun Park et al.Canadian journal of physiology and pharmacology, 92(12), 993-999 (2014-11-14) High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection.Connie M Remsberg et al.Journal of pharmaceutical and biomedical analysis, 43(1), 250-254 (2006-08-04) Porphyromonas gingivalis is highly sensitive to inhibitors of a proton-pumping ATPase.Mizuki Sekiya et al.Biochemical and biophysical research communications, 498(4), 837-841 (2018-03-14) Involvement of nuclear factor-kappaB in the inhibition of pro-inflammatory mediators by pinosylvin.Jongsung Lee et al.Planta medica, 72(9), 801-806 (2006-06-20) The O-methyltransferase PMT2 mediates methylation of pinosylvin in Scots pine.Tanja Paasela et al.The New phytologist, 214(4), 1537-1550 (2017-03-02) Does cryptic microbiota mitigate pine resistance to an invasive beetle-fungus complex? Implications for invasion potential.Chihang Cheng et al.Scientific reports, 6, 33110-33110 (2016-09-14) Metabolic engineering of Escherichia coli for the synthesis of the plant polyphenol pinosylvin.Philana Veronica van Summeren-Wesenhagen et al.Applied and environmental microbiology, 81(3), 840-849 (2014-11-16) In vivo effect of pinosylvin and pterostilbene in the animal model of adjuvant arthritis.Tatiana Macickova et al.Neuro endocrinology letters, 31 Suppl 2, 91-95 (2010-12-29) Screening analyses of pinosylvin stilbenes, resin acids and lignans in Norwegian conifers.Hanne Hovelstad et al.Molecules (Basel, Switzerland), 11(1), 103-114 (2007-10-27) Attenuating Effects of Nortrachelogenin on IL-4 and IL-13 Induced Alternative Macrophage Activation and on Bleomycin-Induced Dermal Fibrosis.Antti Pemmari et al.Journal of agricultural and food chemistry, 66(51), 13405-13413 (2018-11-22) Nuclear factor E2-related factor 2-mediated induction of NAD(P)H:quinone oxidoreductase 1 by 3,5-dimethoxy-trans-stilbene.Eun-Jung Park et al.Journal of pharmacological sciences, 116(1), 89-96 (2011-04-23) The natural stilbenoid pinosylvin and activated neutrophils: effects on oxidative burst, protein kinase C, apoptosis and efficiency in adjuvant arthritis.Viera Jančinová et al.Acta pharmacologica Sinica, 33(10), 1285-1292 (2012-07-31) Pharmacometrics of stilbenes: seguing towards the clinic.Kathryn A Roupe et al.Current clinical pharmacology, 1(1), 81-101 (2008-08-01) Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.Mu-Kuan Chen et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 117, 109160-109160 (2019-08-08) Pinosylvin Induces Cell Survival, Migration and Anti-Adhesiveness of Endothelial Cells via Nitric Oxide Production.Jeong E, Lee HR, Pyee J, Park H. Phytotherapy Research (2012) Biphenyl 4-Hydroxylases Involved in Aucuparin Biosynthesis in Rowan and Apple Are Cytochrome P450 736A Proteins.Debabrata Sircar et al.Plant physiology, 168(2), 428-442 (2015-04-12) Pinosylvin induces cell survival, migration and anti-adhesiveness of endothelial cells via nitric oxide production.Eunsil Jeong et al.Phytotherapy research : PTR, 27(4), 610-617 (2012-06-28) Association genetics of phenolic needle compounds in Norway spruce with variable susceptibility to needle bladder rust.Andrea Ganthaler et al.Plant molecular biology, 94(3), 229-251 (2017-02-13) Developmental Changes in Scots Pine Transcriptome during Heartwood Formation.Kean-Jin Lim et al.Plant physiology, 172(3), 1403-1417 (2016-09-08) Bioactivity guided isolation of anticancer constituents from leaves of Alnus sieboldiana (Betulaceae).A Ludwiczuk et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(6), 491-498 (2010-11-30) Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species.Michael Adams et al.Journal of natural products, 68(1), 83-85 (2005-02-01) Oxyresveratrol activates parallel apoptotic and autophagic cell death pathways in neuroblastoma cells.Md Ataur Rahman et al.Biochimica et biophysica acta, 1861(2), 23-36 (2016-11-07) Separation and isolation of major polyphenols from maritime pine (Pinus pinaster) knots by two-step centrifugal partition chromatography monitored by LC-MS and NMR spectroscopy.Julien Gabaston et al.Journal of separation science, 43(6), 1080-1088 (2020-01-24)

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