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N,N-Diphenylcarbamic acid 9-[(2R,6S)-6-[[[chloro(dimethylamino)phosphinyl]oxy]methyl]-4-(triphenylmethyl)-2-morpholinyl]-2-[(2-methyl-1-oxopropyl)amino]-9H-purin-6-yl ester | CAS:1357354-76-7
N,N-Diphenylcarbamic acid 9-[(2R,6S)-6-[[[chloro(dimethylamino)phosphinyl]oxy]methyl]-4-(triphenylmethyl)-2-morpholinyl]-2-[(2-methyl-1-oxopropyl)amino]-9H-purin-6-yl ester
  • Name:N,N-Diphenylcarbamic acid 9-[(2R,6S)-6-[[[chloro(dimethylamino)phosphinyl]oxy]methyl]-4-(triphenylmethyl)-2-morpholinyl]-2-[(2-methyl-1-oxopropyl)amino]-9H-purin-6-yl ester
  • CAS:1357354-76-7
  • Synonyms:
  • Molecular Formula:C48H48ClN8O6P
  • Molecular Weight:899.37
  • EINESC:

Description

Properties

Density 1.32±0.1 g/cm3 (20 ºC

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Peer-Reviewed Papers
Direct-oxidative DNA damage and apoptosis induction in different human respiratory cells exposed to low concentrations of sodium chromate.Delia Cavallo et al.Journal of applied toxicology : JAT, 30(3), 218-225 (2009-10-20) Differential impact of ionic and coordinate covalent chromium (Cr)-DNA binding on DNA replication.Jamie L Fornsaglio et al.Molecular and cellular biochemistry, 279(1-2), 149-155 (2005-11-12) Medaka (Oryzias latipes) as a sentinel species for aquatic animals: Medaka cells exhibit a similar genotoxic response as North Atlantic right whale cells.John Pierce Wise et al.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 149(2), 210-214 (2008-10-22) Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure.Daryl E Pritchard et al.Molecular and cellular biochemistry, 279(1-2), 169-181 (2005-11-12) Studies on the acute biochemical effects of La(NO3)3 using 1H NMR spectroscopy of urine combined with pattern recognition.Huifeng Wu et al.Journal of inorganic biochemistry, 99(2), 644-650 (2004-12-29) Cytotoxicity and genotoxicity of hexavalent chromium in human and North Atlantic right whale (Eubalaena glacialis) lung cells.Tânia Li Chen et al.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 150(4), 487-494 (2009-07-28) Sodium chromate oxidation of enol benzoates. Allylic oxidation versus a novel rearrangement.Goldblum A and Mechoulam R Journal of the Chemical Society. Perkin Transactions 1, (17), 1889-1898 (1977) Temporal decrease of trivalent chromium concentration in a standardized algal culture medium: experimental results and implications for toxicity evaluation.Davide A L Vignati et al.Bulletin of environmental contamination and toxicology, 80(4), 305-310 (2008-03-18) Elucidation of the percutaneous absorption of chromium compounds by functional proteomics.Tai-Long Pan et al.Proteomics, 9(22), 5120-5131 (2009-09-23) Cumulative genotoxic and apoptotic effects of xenobiotics in a mini organ culture model of human nasal mucosa as detected by the alkaline single cell microgel electrophoresis assay and the annexin V-affinity assay.Michael Buehrlen et al.Toxicology letters, 169(2), 152-161 (2007-02-20) Comparison between acetic acid and landfill leachates for the leaching of Pb(II), Cd(II), As(V), and Cr(VI) from cementitious wastes.Cheryl E Halim et al.Environmental science & technology, 38(14), 3977-3983 (2004-08-10) Clinical significance of optimal red cell mass and plasma volume estimation methods.Mila V Todorović-Tirnanić et al.Nuclear medicine review. Central & Eastern Europe, 7(1), 31-38 (2004-08-20) The cytotoxicity and genotoxicity of hexavalent chromium in medaka (Oryzias latipes) cells.Britton C Goodale et al.Aquatic toxicology (Amsterdam, Netherlands), 87(1), 60-67 (2008-03-04) Particulate and soluble hexavalent chromium are cytotoxic and genotoxic to human lung epithelial cells.Sandra S Wise et al.Mutation research, 610(1-2), 2-7 (2006-07-29) Stability, antigenicity, and aggregation of Moraxella bovis cytolysin after purification and storage.Lisle W George et al.American journal of veterinary research, 65(7), 977-983 (2004-07-30) Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells.Judith M Myers et al.Toxicology, 246(2-3), 222-233 (2008-03-11) Comparative cytotoxicity and genotoxicity of particulate and soluble hexavalent chromium in human and sperm whale (Physeter macrocephalus) skin cells.Tânia Li Chen et al.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 155(1), 143-150 (2011-04-07) XRCC1 protects cells from chromate-induced chromosome damage, but does not affect cytotoxicity.Eliza Grlickova-Duzevik et al.Mutation research, 610(1-2), 31-37 (2006-08-15) Chromium-induced genotoxicity and interference in human lymphoblastoid cell (TK6) repair processes.Naouale El-Yamani et al.Journal of toxicology and environmental health. Part A, 74(15-16), 1030-1039 (2011-06-29) A comparative study of the JAM test and 51Cr-release assay to assess the cytotoxicity of dendritic cells on hematopoietic tumor cells.Flávio M Ayres et al.Immunological investigations, 32(4), 219-227 (2003-11-08) Versatility of capillary electrophoresis of anions with a high mobility chromate electrolyte.Oehrle S A. Journal of Chromatography A, 671(1-2), 383-387 (1994) Changes of 8-OH-dG levels in DNA and its base excision repair activity in rat lungs after inhalation exposure to hexavalent chromium.Seung-Hee Maeng et al.Mutation research, 539(1-2), 109-116 (2003-09-02) A study of the pollution of the Aries River (Romania) using capillary electrophoresis as analytical technique.Forray F L and Hallbauer D K Environmental Geology, 39(12), 1372-1384 (2000) Human lung cell growth is not stimulated by lead ions after lead chromate-induced genotoxicity.Sandra S Wise et al.Molecular and cellular biochemistry, 279(1-2), 75-84 (2005-11-12) Surface complexation modeling of Cr(VI) adsorption at the goethite-water interface.Jinyu Xie et al.Journal of colloid and interface science, 455, 55-62 (2015-06-10) The clastogenic effects of chronic exposure to particulate and soluble Cr(VI) in human lung cells.Amie L Holmes et al.Mutation research, 610(1-2), 8-13 (2006-07-28) Carcinogenic lead chromate induces DNA double-strand breaks in human lung cells.Hong Xie et al.Mutation research, 586(2), 160-172 (2005-08-23) Chromium oxidation state imaging in mammalian cells exposed in vitro to soluble or particulate chromate compounds.Richard Ortega et al.Chemical research in toxicology, 18(10), 1512-1519 (2006-03-15) Developmental toxicity, uptake and distribution of sodium chromate assayed by frog embryo teratogenesis assay-Xenopus(FETAX).Stefano Bosisio et al.The Science of the total environment, 407(18), 5039-5045 (2009-06-23)
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