Melting point	76-78 ºC

Symbol(GHS)	Xn
Hazard Codes	R40
SDS/MSDS	S36/37

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

The difluorotoluene debate--a decade later.Eric T Kool et al.Chemical communications (Cambridge, England), (35)(35), 3665-3675 (2006-10-19) Bi-stranded, multisite replication of a base pair between difluorotoluene and adenine: confirmation by 'inverse' sequencing.D Liu et al.Chemistry & biology, 4(12), 919-926 (1998-03-07) Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules.Wenonah A Vercoutere et al.Nucleic acids research, 31(4), 1311-1318 (2003-02-13) Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta.M Todd Washington et al.Molecular and cellular biology, 23(14), 5107-5112 (2003-07-02) DNA curvature at A tracts containing a non-polar thymine mimic.Angèle Maki et al.Nucleic acids research, 31(3), 1059-1066 (2003-02-01) Solution structure of a DNA duplex containing a guanine-difluorotoluene pair: a wobble pair without hydrogen bonding?Danielle A Pfaff et al.Journal of the American Chemical Society, 130(14), 4869-4878 (2008-03-18) Aromatic Nonpolar Nucleosides as Hydrophobic Isosteres of Pyrimidine and Purine Nucleosides.Barbara A Schweitzer et al.The Journal of organic chemistry, 59(24), 7238-7242 (1994-12-01) Recognition of GT mismatches by Vsr mismatch endonuclease.K R Fox et al.Nucleic acids research, 28(13), 2535-2540 (2000-06-28) Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex.Shuangluo Xia et al.Journal of the American Chemical Society, 133(26), 10003-10005 (2011-06-15) Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa.William T Wolfle et al.Molecular and cellular biology, 25(16), 7137-7143 (2005-08-02) A thymine isostere in the templating position disrupts assembly of the closed DNA polymerase beta ternary complex.Thomas W Kirby et al.Biochemistry, 44(46), 15230-15237 (2005-11-16) Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography.Pradeep S Pallan et al.Journal of the American Chemical Society, 131(35), 12548-12549 (2009-08-19) Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair.K M Guckian et al.Nature structural biology, 5(11), 954-959 (1998-11-10) Quantum-chemical ab initio study on the adenine-difluorotoluene complex--a mimic for the adenine-thymine base pair.M Meyer et al.Journal of biomolecular structure & dynamics, 15(3), 619-624 (1998-01-24) Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.Lyudmila Yakovleva et al.The Journal of biological chemistry, 281(47), 35914-35921 (2006-09-29) Interaction and solvation energies of nonpolar DNA base analogues and their role in polymerase insertion fidelity.D Barsky et al.Journal of biomolecular structure & dynamics, 16(6), 1119-1134 (1999-08-14) Molecular moment similarity between several nucleoside analogs of thymidine and thymidine. [email protected] D Silverman et al.Journal of biomolecular structure & dynamics, 16(6), 1169-1175 (1999-08-14) Importance of terminal base pair hydrogen-bonding in 3'-end proofreading by the Klenow fragment of DNA polymerase I.J C Morales et al.Biochemistry, 39(10), 2626-2632 (2000-03-08) Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene.Adriana Irimia et al.The Journal of biological chemistry, 282(50), 36421-36433 (2007-10-24) Novel modifications in RNA.Kelly Phelps et al.ACS chemical biology, 7(1), 100-109 (2011-12-14) Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue.Shuangluo Xia et al.Biochemistry, 51(7), 1476-1485 (2012-02-07)

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