Water Solubility	decompose
Boiling point	125-126 ºC
Flash point	10 ºC
Density	0.767
Refractive index	1.4103-1.4123

Symbol(GHS)	F;C
Hazard Codes	R11;R34
SDS/MSDS	S16;S24/25

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

The efficacy of triclabendazole and other anthelmintics against Fasciola hepatica in controlled studies in cattle.R J Richards et al.The Veterinary record, 126(9), 213-216 (1990-03-03) Multi-residue determination of phenolic and salicylanilide anthelmintics and related compounds in bovine kidney by liquid chromatography-tandem mass spectrometry.Caldow M, et al. Journal of Chromatography A, 1216(46), 8200-8205 (2009) Evaluation of nitroxynil and closantel activity using ELISA and egg counts against Fasciola hepatica in experimentally and naturally infected cattle.C Boulard et al.Veterinary research, 26(4), 249-255 (1995-01-01) Determination of nitroxynil in cow milk by reversed-phase high-performance liquid chromatography with dual-electrode coulometric detection.K Takeba et al.Journal of chromatography, 596(1), 67-71 (1992-04-03) Experiments on anthelmintic control of Fasciola hepatica in Brazil.F A Echevarria et al.Veterinary parasitology, 43(3-4), 211-222 (1992-07-01) Efficacy of an injectable combination anthelmintic (nitroxynil+clorsulon+ivermectin) against early immature Fasciola hepatica compared to triclabendazole combination flukicides given orally or topically to cattle.G W Hutchinson et al.Veterinary parasitology, 162(3-4), 278-284 (2009-04-21) [Study of plasma and hepatic hydrolysis of nitroxinil derivatives].G Baziard-Mouysset et al.Annales pharmaceutiques francaises, 54(5), 223-227 (1996-01-01) Determination of nitroxynil residues in tissues using high-performance liquid chromatography-thermospray mass spectrometry.W J Blanchflower et al.The Analyst, 114(9), 1013-1015 (1989-09-01) In vitro metabolism of aromatic nitriles.B Markus et al.Journal of pharmaceutical sciences, 83(12), 1729-1734 (1994-12-01) Ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo and in vitro drug treatment with nitroxynil (Trodax).B McKinstry et al.Parasitology research, 101(4), 929-941 (2007-06-09) Combined subcutaneous administration of ivermectin and nitroxynil in sheep: age/body weight related changes to the kinetic disposition of both compounds.L Moreno et al.Research in veterinary science, 88(2), 315-320 (2009-11-07) High-performance liquid chromatographic method for the determination of the anthelmintic nitroxynil in cattle muscle tissue with on-line anion-exchange clean-up.J A Tarbin et al.Journal of chromatography, 613(2), 347-353 (1993-04-02) Immunological detection of chemotherapeutic success in bovine fasciolosis using the specific antigen f2.D Levieux et al.Veterinary parasitology, 45(1-2), 81-88 (1992-12-01) Development and Optimisation of a Multiresidue Method for the Determination of 40 Anthelmintic Compounds in Environmental Water Samples by Solid Phase Extraction (SPE) with LC-MS/MS Detection.Damien Mooney et al.Molecules (Basel, Switzerland), 24(10) (2019-05-28) [Investigation of the residue of the fasciolicide nitroxynil in milk and dairy products].K Takeba et al.[Nihon koshu eisei zasshi] Japanese journal of public health, 39(2), 75-82 (1992-02-01) Efficacy of nitroxynil against Fasciola hepatica resistant to triclabendazole in a naturally infected sheep flock.Maria Martínez-Valladares et al.Parasitology research, 107(5), 1205-1211 (2010-08-04) Plasma protein binding of nitroxynil in several species.M Alvinerie et al.Journal of veterinary pharmacology and therapeutics, 14(2), 170-173 (1991-06-01) Efficacy of nitroxynil against ivermectin, benzimidazole and salicylanilide resistant H contortus.P C Jeannin et al.The Veterinary record, 126(25), 624-625 (1990-06-23) How long before resistance makes it impossible to control some field strains of Haemonchus contortus in South Africa with any of the modern anthelmintics?J A van Wyk et al.Veterinary parasitology, 70(1-3), 111-122 (1997-06-01) Morphological response of triclabendazole-susceptible and triclabendazole-resistant isolates of Fasciola hepatica to treatment in vitro with nitroxynil (Trodax).B McKinstry et al.Parasitology research, 104(3), 645-655 (2008-11-19) Determination of bithionol, bromophen, nitroxynil, oxyclozanide, and tribromsalan in milk with liquid chromatography coupled with tandem mass spectrometry.Miho Sakamoto et al.Journal of AOAC International, 93(4), 1340-1346 (2010-10-07) Efficacy of glutathione for treatment of fascioliasis. An investigation in the experimentally infested rat.R Maffei Facino et al.Arzneimittel-Forschung, 43(4), 455-460 (1993-04-01) Fasciola hepatica: tegumental surface alterations following treatment in vivo and in vitro with nitroxynil (Trodax).B McKinstry et al.Parasitology research, 91(3), 251-263 (2003-08-26) Fasciolicides: efficacy, actions, resistance and its management.I Fairweather et al.Veterinary journal (London, England : 1997), 158(2), 81-112 (1999-09-18) Activity of oxyclozanide, nitroxynil, clorsulon and albendazole against adult triclabendazole-resistant Fasciola hepatica.G C Coles et al.The Veterinary record, 148(23), 723-724 (2001-06-30) RP-HPLC Method Development and Validation for Nitroxynil in Active Pharmaceutical Ingredient Manufacturing.Yelamanchi KSV, et al. Journal of Pharmaceutical Sciences and Research, 8(9), 967-967 (2016) Essential Drug Data for Rational Therapy in Veterinary Practice (2014) Anaerobic Metabolism of the Agro-Pesticide Nitroxinil by Bovine Ruminal Fluid.Irazoqui I, et al. Drug Metabolism Letters, 8(2), 101-108 (2014) Voltammetric assay of the anthelmintic veterinary drug nitroxynil in bulk form and formulation at a mercury electrode.M M Ghoneim et al.Journal of pharmaceutical and biomedical analysis, 41(4), 1268-1273 (2006-05-12) Investigation of the persistence of nitroxynil residues in milk from lactating dairy cows by ultra performance liquid chromatography tandem mass spectrometry.Michelle Whelan et al.Journal of agricultural and food chemistry, 59(14), 7793-7797 (2011-06-11)

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