Melting point	226 ºC
Water Solubility	freely soluble

Symbol(GHS)	Xn
Hazard Codes	R22
SDS/MSDS	S22

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS
(3,4-Dimethoxyphenyl)acetonitrile	93-17-4	View

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Articles

Peer-Reviewed Papers

Antiproliferative effect of α-mangostin on canine osteosarcoma cells.Aungkana Krajarng et al.Research in veterinary science, 93(2), 788-794 (2012-02-22) Alpha-mangostin induces apoptosis through activation of reactive oxygen species and ASK1/p38 signaling pathway in cervical cancer cells.Chien-Hsing Lee et al.Oncotarget, 8(29), 47425-47439 (2017-05-26) Significant anti-invasive activities of α-mangostin from the mangosteen pericarp on two human skin cancer cell lines.Jing J Wang et al.Anticancer research, 32(9), 3805-3816 (2012-09-21) Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting.Jun-Jie Koh et al.Biochimica et biophysica acta, 1828(2), 834-844 (2012-09-18) Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes.Berenice Márquez-Valadez et al.Nutritional neuroscience, 15(5), 13-19 (2012-12-13) Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death.Laura María Reyes-Fermín et al.Nutritional neuroscience, 15(5), 34-41 (2012-07-11) Α-mangostin, a polyphenolic xanthone derivative from mangosteen, attenuates β-amyloid oligomers-induced neurotoxicity by inhibiting amyloid aggregation.Yan Wang et al.Neuropharmacology, 62(2), 871-881 (2011-10-01) Anti-angiogenic effect of α-mangostin.Tomoko Shiozaki et al.Journal of natural medicines, 67(1), 202-206 (2012-03-03) Α-mangostin and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach.Mariana Leão et al.Journal of natural products, 76(4), 774-778 (2013-04-02) Alterations in cell cycle and induction of apoptotic cell death in breast cancer cells treated with α-mangostin extracted from mangosteen pericarp.Hitomi Kurose et al.Journal of biomedicine & biotechnology, 2012, 672428-672428 (2012-05-12) Alpha-mangostin suppresses IL-6 and IL-8 expression in P. gingivalis LPS-stimulated human gingival fibroblasts.Ichaya Yiemwattana et al.Odontology, 103(3), 348-355 (2014-06-04) Potent activity against multidrug-resistant Mycobacterium tuberculosis of α-mangostin analogs.Pichit Sudta et al.Chemical & pharmaceutical bulletin, 61(2), 194-203 (2012-11-15) Mangosteen xanthones mitigate ovalbumin-induced airway inflammation in a mouse model of asthma.Ha-Young Jang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(11), 4042-4050 (2012-09-05) Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia.Patricia P Jumbo-Lucioni et al.Disease models & mechanisms, 6(1), 84-94 (2012-07-10) In vivo toxicity and antitumor activity of mangosteen extract.Nuttavut Kosem et al.Journal of natural medicines, 67(2), 255-263 (2012-05-25) Apoptosis, antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f.Muhammad Taher et al.Asian Pacific journal of tropical medicine, 5(2), 136-141 (2012-01-10) Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites.Chureeporn Chitchumroonchokchai et al.Molecular nutrition & food research, 57(2), 203-211 (2012-12-15) [Optimize technique of extracting alpha-mangostin from pericarp of Garcinia mangostana by supersonic wave using central composite design-response surface methodology].Yan Zhao et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(6), 973-977 (2012-12-15) DNA Protection against Oxidative Damage Using the Hydroalcoholic Extract of Garcinia mangostana and Alpha-Mangostin.Carvalho-Silva R Evidence-Based Complementary and Alternative Medicine : ECAM, 2016, 3430405-3430405 (2016) A miniaturized flow-through cell to evaluate skin permeation of endoxifen.Choon Siong Mah et al.International journal of pharmaceutics, 441(1-2), 433-440 (2012-11-24) Solid dispersions of α-mangostin improve its aqueous solubility through self-assembly of nanomicelles.Abdalrahim F A Aisha et al.Journal of pharmaceutical sciences, 101(2), 815-825 (2011-11-15) Protective effect of alpha-mangostin against oxidative stress induced-retinal cell death.Yuan Fang et al.Scientific reports, 6, 21018-21018 (2016-02-19) alpha-Mangostin enhances betulinic acid cytotoxicity and inhibits cisplatin cytotoxicity on HCT 116 colorectal carcinoma cells.Abdalrahim F A Aisha et al.Molecules (Basel, Switzerland), 17(3), 2939-2954 (2012-03-10) α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth.Jeremy J Johnson et al.Carcinogenesis, 33(2), 413-419 (2011-12-14) Alpha-Mangostin-Rich Extracts from Mangosteen Pericarp: Optimization of Green Extraction Protocol and Evaluation of Biological Activity.Ali Ghasemzadeh et al.Molecules (Basel, Switzerland), 23(8) (2018-07-26) Protective effect of alpha-mangostin against type-I collagen formation in thioacetamide-induced cirrhotic rat.Raksawan Poonkhum et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95 Suppl 12, S93-S98 (2013-03-22) Inhibition of human aldose reductase-like protein (AKR1B10) by α- and γ-mangostins, major components of pericarps of mangosteen.Midori Soda et al.Biological & pharmaceutical bulletin, 35(11), 2075-2080 (2012-11-06) New "hyphenated" CPC-HPLC-DAD-MS strategy for simultaneous isolation, analysis and identification of phytochemicals: application to xanthones from Garcinia mangostana.Thomas Michel et al.Analytical and bioanalytical chemistry, 404(10), 2963-2972 (2012-10-12) α-Mangostin induces apoptosis and suppresses differentiation of 3T3-L1 cells via inhibiting fatty acid synthase.Xiaofang Quan et al.PloS one, 7(3), e33376-e33376 (2012-03-20) Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults.Chureeporn Chitchumroonchokchai et al.The Journal of nutrition, 142(4), 675-680 (2012-03-09)

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