Melting point	245 ºC (分解)**
Density	1.7 g/cm3*

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

SiO2 mediated reaction of isatin with N-halosaccharins: A regiospecific preparation of 5-haloisatins.de Souza SPL, et al. Heterocyclic Communications, 9(1), 31-34 (2003) In vitro cytotoxicity evaluation of some substituted isatin derivatives.Kara L Vine et al.Bioorganic & medicinal chemistry, 15(2), 931-938 (2006-11-08) The Structures of the Bromodioxindoles of Baeyer and Knop.Sumpter WC. Journal of the American Chemical Society, 67(7), 1140-1141 (1945) Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.Janice L Hyatt et al.Journal of medicinal chemistry, 50(8), 1876-1885 (2007-03-24) Superelectrophiles in aromatic polymer chemistry.Colquhoun HM, et al. Macromolecules, 34(4), 1122-1124 (2001) [The positive inotropic activity of 5-bromoisatin (5-bromo-indoline-2,3-dione)].V Garalene Eksperimental'naia i klinicheskaia farmakologiia, 62(3), 20-24 (1999-08-10) Isatins Inhibit N5-CAIR Synthetase by a Substrate Depletion Mechanism.Cale C Streeter et al.Biochemistry, 58(17), 2260-2268 (2019-04-10) Acylideneoxoindoles: a new class of reversible inhibitors of human transglutaminase 2.Cornelius Klöck et al.Bioorganic & medicinal chemistry letters, 21(9), 2692-2696 (2011-01-11) Quick and efficient synthesis of Morita-Baylis-Hillman adducts of isatin derivatives.Rad-Moghadam K and Youseftabar-Miri L. ARKIVOC (Gainesville, FL, United States), 11, 43-50 (2011) Electro-organic synthesis of nanosized particles of 3-hydroxy-3-(1H-indol-3-yl) indolin-2-one derivatives.Makarem S, et al. Monatshefte fur Chemie / Chemical Monthly, 148(8), 1157-1160 (2012) A green approach for efficient synthesis of N-substituted pyrroles in ionic liquid under microwave irradiation.Meshram HM, et al. Tetrahedron Letters, 51(27), 3477-3480 (2010) Synthesis and spectral data for cinchoninic acids.Sarkis GY. Journal of Chemical and Engineering Data, 17(3), 388-391 (1972) Synthesis, characterization and cytotoxic activity of S-benzyldithiocarbazate Schiff bases derived from 5-fluoroisatin, 5-chloroisatin, 5-bromoisatin and their crystal structures.Manan MAFA, et al. Journal of Chemical Crystallography, 41(11), 1630-1641 (2011) Mass spectrometry imaging reveals new biological roles for choline esters and Tyrian purple precursors in muricid molluscs.David Rudd et al.Scientific reports, 5, 13408-13408 (2015-09-02) Possible psychopharmacological agents. X. Synthesis of Some Fluorine Containing Indole-2, 3-dione Derivatives.Joshi KC, et al. J. Prakt. Chem., 322(2), 314-320 (1980) [Effect of isatin and its derivatives on some indicators of carbohydrate metabolism].V N Garalene et al.Voprosy meditsinskoi khimii, 30(5), 56-59 (1984-09-01) A practical large-scale preparation of 5'-bromospiro (cyclohexane-1,3-[3H] indol)-2'(1'H)-one.Wilk BK, et al. Organic preparations and procedures international, 37(3), 283-285 (2005) Synthesis of isatin and 5-bromoisatin derivatives.Mesropyan EG, et al. Russ. J. Org. Chem., 37(10), 1476-1477 (2001) A facile one-pot method for the preparation of N-alkyl isatins under microwave irradiation.Azizian J, et al. Synthetic Communications, 33(5), 789-793 (2003) QSAR study of isatin analogues as in vitro anti-cancer agents.Razieh Sabet et al.European journal of medicinal chemistry, 45(3), 1113-1118 (2010-01-09)

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