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Phentolamine hydrochloride | CAS:73-05-2
Phentolamine hydrochloride
  • Name:Phentolamine hydrochloride
  • CAS:73-05-2
  • Synonyms:3-[4,5-Dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol hydrochloride
  • Molecular Formula:C17H19N3O.HCl
  • Molecular Weight:317.81
  • EINESC:200-793-5

Description

Properties

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Safety

Symbol(GHS) Xn
Hazard Codes R22
SDS/MSDS S22;S24/25

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Disinfection Byproducts Bind Human Estrogen Receptor-α.Breanne E Holmes et al.Environmental toxicology and chemistry, 38(5), 956-964 (2019-01-31) Glutathione and N-acetylcysteine inactivations of mutagenic 2(5H)-furanones from the chlorination of humics in water.R T LaLonde et al.Chemical research in toxicology, 6(4), 445-451 (1993-07-01) Induction of genotoxic effects by chlorohydroxyfuranones, byproducts of water disinfection, in E. coli K-12 cells recovered from various organs of mice.K Fekadu et al.Environmental and molecular mutagenesis, 24(4), 317-324 (1994-01-01) Novel anti-bacterials against MRSA: synthesis of focussed combinatorial libraries of tri-substituted 2(5H)-furanones.Eric Lattmann et al.Current drug discovery technologies, 3(2), 125-134 (2006-08-24) Mutagenicity in vitro of 3,4-dichloro-5-hydroxy-2(5H)-furanone (mucochloric acid), a chlorine disinfection by-product in drinking water.K Jansson et al.Environmental and molecular mutagenesis, 25(4), 284-287 (1995-01-01) Formation of ethenocarbaldehyde derivatives of adenosine and cytidine in reactions with mucochloric acid.L Kronberg et al.Chemical research in toxicology, 6(4), 495-499 (1993-07-01) Mucochloric acid action on phi X174 DNA: a comparison to other chlorine-substituted 2(5H)-furanones.R T LaLonde et al.Chemical research in toxicology, 10(2), 205-210 (1997-02-01) Reaction of mucochloric and mucobromic acids with adenosine and cytidine: formation of chloro- and bromopropenal derivatives.L Kronberg et al.Chemical research in toxicology, 9(8), 1257-1263 (1996-12-01) Reactivity of mucohalic acids in water.Rafael Gómez-Bombarelli et al.Water research, 45(2), 714-720 (2010-09-22) Identification of endocrine active disinfection by-products (DBPs) that bind to the androgen receptor.Breanne E Holmes et al.Chemosphere, 187, 114-122 (2017-08-27) Effect of beta-cyclodextrin on mucochloric acid and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone.I R Politzer et al.Archives of environmental contamination and toxicology, 20(3), 371-374 (1991-04-01) Formation of 3,N4-ethenocytidine, 1,N6-ethenoadenosine, and 1,N2-ethenoguanosine in reactions of mucochloric acid with nucleosides.L Kronberg et al.Chemical research in toxicology, 5(6), 852-855 (1992-11-01) Novel synthons from mucochloric acid: the first use of alpha,beta-dichloro-gamma-butenolides and gamma-butyrolactams for direct vinylogous aldol addition.Koushik Das Sarma et al.The Journal of organic chemistry, 72(9), 3311-3318 (2007-04-03) Test of chiral recognition in the Salmonella typhimurium (TA100) mutagenicity of mucochloric acid-cysteine adducts.R T LaLonde et al.Environmental and molecular mutagenesis, 22(3), 181-187 (1993-01-01) The toxicity of the mutagen 'MX' and its analogue, mucochloric acid, to rainbow trout hepatocytes and gill epithelial cells and to Daphnia magna.B Isomaa et al.Toxicology, 100(1-3), 69-77 (1995-06-26) The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone(mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, balb/ca mice or C57bl/6J-min mice.I L Steffensen et al.Pharmacology & toxicology, 85(2), 56-64 (1999-09-17) Unraveling the Molecular Mechanism of Selective Antimicrobial Activity of 2(5H)-Furanone Derivative against Staphylococcus aureus.Irshad S Sharafutdinov et al.International journal of molecular sciences, 20(3) (2019-02-10) A study of inactivation reactions of N-acetylcysteine with mucochloric acid, a mutagenic product of the chlorination of humic substances in water.R T LaLonde et al.Chemical research in toxicology, 5(5), 618-624 (1992-09-01) Reaction of mucochloric acid with adenosine: formation of 8-(N6-adenosinyl)ethenoadenosine derivatives.D Asplund et al.Chemical research in toxicology, 8(6), 841-846 (1995-09-01) Oxidation and radical intermediates associated with the glutathione conjugation of mucochloric acid.R T LaLonde et al.Chemical research in toxicology, 7(4), 482-486 (1994-07-01) First direct reductive amination of mucochloric acid: a simple and efficient method for preparing highly functionalized alpha,beta-unsaturated gamma-butyrolactams.Ji Zhang et al.Organic letters, 5(4), 553-556 (2003-02-14)
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