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L-Tryptophan | CAS:73-22-3 (80206-30-0)
L-Tryptophan
  • Name:L-Tryptophan
  • CAS:73-22-3 (80206-30-0)
  • Synonyms:L(-)-Tryptophan; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid; L-alphs-Amino-3-indolepropionic acid; Indole-3-alanine; Trp
  • Molecular Formula:C11H12N2O2
  • Molecular Weight:204.23
  • EINESC:

Description

Properties

Melting point 280-285 ºC
Specific optical rotation -31.1 º (c=1, H20)
Water Solubility 11.4 g/L (25 ºC)
Density 1.34

Safety

SDS/MSDS S24/25

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
The role of P-glycoprotein in intestinal transport versus the BBB transport of tetraphenylphosphonium.Avi Swed et al.Molecular pharmaceutics, 6(6), 1883-1890 (2009-09-03) Capillary electrophoresis of chitooligosaccharides in acidic solution: simple determination using a quaternary-ammonium-modified column and indirect photometric detection with crystal violet.Toshiaki Hattori et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(3-4), 477-480 (2009-12-17) Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii.Vijaya Bharathi Srinivasan et al.Antimicrobial agents and chemotherapy, 53(12), 5312-5316 (2009-09-23) Programmed cell death in plants: protective effect of tetraphenylphosphonium and tetramethylrhodamine cations used as transmembrane quinone carriers.L A Vasil'ev et al.Biochemistry. Biokhimiia, 77(4), 354-361 (2012-07-20) Assessment of the activity of RND-type multidrug efflux pumps in Pseudomonas aeruginosa using tetraphenylphosphonium ions.Rimantas Daugelavicius et al.International journal of antimicrobial agents, 36(3), 234-238 (2010-05-22) 4-[18F]-tetraphenylphosphonium as a PET tracer for myocardial mitochondrial membrane potential.Gagandeep S Gurm et al.JACC. Cardiovascular imaging, 5(3), 285-292 (2012-03-17) Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore.Fedor F Severin et al.Proceedings of the National Academy of Sciences of the United States of America, 107(2), 663-668 (2010-01-19) Efficient Perovskite Solar Cells with Reduced Photocurrent Hysteresis through Tuned Crystallinity of Hybrid Perovskite Thin Films.Qi J, et al. ACS Omega, 3(6), 7069-7076 (2018) Fluoroquinolone efflux by the plasmid-mediated multidrug efflux pump QacB variant QacBIII in Staphylococcus aureus.Hidemasa Nakaminami et al.Antimicrobial agents and chemotherapy, 54(10), 4107-4111 (2010-07-28) Tetraarylphosphonium Halides as Arylating Reagents in Pd?Catalyzed Heck and Cross?Coupling Reactions.Hwang L K, et al. Angewandte Chemie (International Edition in English), 44(38), 6166-6169 (2005) In situ monitoring of photodynamic inactivation of the membrane functions of bacteria using electrochemical sensors.Hisato Kato et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 26(10), 1019-1021 (2010-10-19) Evaluation of the electrical potential on the membrane of the extremely alkaliphilic bacterium Thioalkalivibrio.M S Muntyan et al.Biochemistry. Biokhimiia, 77(8), 917-924 (2012-08-07) Developmental upregulation of presynaptic NCKX underlies the decrease of mitochondria-dependent posttetanic potentiation at the rat calyx of Held synapse.Jae Sung Lee et al.Journal of neurophysiology, 109(7), 1724-1734 (2013-01-04) Structure, dynamics, and substrate-induced conformational changes of the multidrug transporter EmrE in liposomes.Sepan T Amadi et al.The Journal of biological chemistry, 285(34), 26710-26718 (2010-06-17) Mitochondrial membrane potential (ΔΨ) fluctuations associated with the metabolic states of mitochondria.Carlos M Palmeira et al.Methods in molecular biology (Clifton, N.J.), 810, 89-101 (2011-11-08) Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase.Faiza Waheed et al.American journal of physiology. Cell physiology, 298(6), C1376-C1387 (2010-03-20) Effects of dietary polyunsaturated fatty acids on mitochondrial metabolism in mammalian hibernation.Alexander R Gerson et al.The Journal of experimental biology, 211(Pt 16), 2689-2699 (2008-08-12) Dissection of mechanistic principles of a secondary multidrug efflux protein.Nir Fluman et al.Molecular cell, 47(5), 777-787 (2012-07-31) LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus.Jody L Floyd et al.Antimicrobial agents and chemotherapy, 54(12), 5406-5412 (2010-09-22) Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates.Jürgen A Bohnert et al.Antimicrobial agents and chemotherapy, 54(9), 3770-3775 (2010-07-08) Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.Feng Long et al.Antimicrobial agents and chemotherapy, 52(9), 3052-3060 (2008-07-02) Gene cloning and characterization of MdeA, a novel multidrug efflux pump in Streptococcus mutans.Do Kyun Kim et al.Journal of microbiology and biotechnology, 23(3), 430-435 (2013-03-07) Myocardial imaging for mitochondrial membrane potential.H William Strauss et al.JACC. Cardiovascular imaging, 5(3), 293-296 (2012-03-17) 64Cu-labeled phosphonium cations as PET radiotracers for tumor imaging.Yang Zhou et al.Bioconjugate chemistry, 22(8), 1459-1472 (2011-06-24) Isomerization in Alkynyl-Protected Gold Nanoclusters.Zong-Jie Guan et al.Journal of the American Chemical Society, 142(6), 2995-3001 (2020-01-21) Multimeric forms of the small multidrug resistance protein EmrE in anionic detergent.Denice C Bay et al.Biochimica et biophysica acta, 1798(3), 526-535 (2009-12-29) Identification of a glycine motif required for packing in EmrE, a multidrug transporter from Escherichia coli.Yael Elbaz et al.The Journal of biological chemistry, 283(18), 12276-12283 (2008-03-07) Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.Liliana Rodrigues et al.Antimicrobial agents and chemotherapy, 57(2), 751-757 (2012-11-21) Continuous real-time monitoring of cationic porphyrin-induced photodynamic inactivation of bacterial membrane functions using electrochemical sensors.Keiko Komagoe et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 10(7), 1181-1188 (2011-04-08) Presynaptic release probability and readily releasable pool size are regulated by two independent mechanisms during posttetanic potentiation at the calyx of Held synapse.Jae Sung Lee et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(32), 7945-7953 (2008-08-08) Lipophilic phosphonium-lanthanide compounds with magnetic, luminescent, and tumor targeting properties.Min Li et al.Journal of inorganic biochemistry, 107(1), 40-46 (2011-12-17) Enhanced antileukemic activity of the novel complex 2,5-dihydroxybenzoate molybdenum(VI) against 2,5-dihydroxybenzoate, polyoxometalate of Mo(VI), and tetraphenylphosphonium in the human HL-60 and K562 leukemic cell lines.Hellinida Thomadaki et al.Journal of medicinal chemistry, 50(6), 1316-1321 (2007-03-03) Chemical speciation of chromium(III) and (VI) using phosphonium cation impregnated polyurethane foams prior to their spectrometric determination.M S El-Shahawi et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 27(7), 757-757 (2011-07-13) Spectroscopic analysis of small multidrug resistance protein EmrE in the presence of various quaternary cation compounds.Denice C Bay et al.Biochimica et biophysica acta, 1818(5), 1318-1331 (2012-02-14) Oxoperoxo molybdenum (vi) and tungsten (vi) and oxodiperoxo molybdate (vi) and tungstate (vi) complexes with 8-quinolinol: synthesis, structure and catalytic activity.Maiti S K, et al. New. J. Chem., 29(4), 554-563 (2005) Mutant huntingtin fails to directly impair brain mitochondria.James Hamilton et al.Journal of neurochemistry, 151(6), 716-731 (2019-08-17)
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