Melting point	210-211 ºC (dec.)
Water Solubility	soluble

Symbol(GHS)	Xn
Hazard Codes	R22;R41;R68
SDS/MSDS	S26;S36/37/39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Polymer synthesis: facilitating functionality.Steve Rimmer Nature chemistry, 2(3), 164-165 (2010-12-03) Catalytic enantioselective protonation of nitronates utilizing an organocatalyst chiral only at sulfur.Kyle L Kimmel et al.Journal of the American Chemical Society, 134(22), 9058-9061 (2012-05-25) Radical cyclization cascades of unsaturated Meldrum's acid derivatives.Brice Sautier et al.Organic letters, 14(1), 146-149 (2011-12-01) New route to 2-substituted indoles by pyrolysis of N-acylacetylphenylhydroxylamines.Hirao K-I, et al. Tetrahedron Letters, 33(11), 1459-1462 (1992) Tetrahedron, 63, 389-389 (2007) Practical asymmetric conjugate alkynylation of Meldrum's acid-derived acceptors: access to chiral beta-alkynyl acids.Sheng Cui et al.Journal of the American Chemical Society, 132(2), 436-437 (2009-12-22) Synthetic Communications, 25, 3067-3067 (1995) Cu(II)-catalyzed aerobic hydroperoxidation of Meldrum's acid derivatives and application in intramolecular oxidation: a conceptual blueprint for O2/H2 dihydroxylation.Scott W Krabbe et al.Organic letters, 14(23), 5932-5935 (2012-11-21) Self-assembled Pd6 open cage with triimidazole walls and the use of its confined nanospace for catalytic Knoevenagel- and Diels-Alder reactions in aqueous medium.Dipak Samanta et al.Chemistry (Weinheim an der Bergstrasse, Germany), 18(39), 12322-12329 (2012-08-18) Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation.Barry M Trost et al.Organic letters, 13(12), 3222-3225 (2011-05-28) Synthetic Communications, 36, 3043-3043 (2006) A novel one-pot three-(in situ five-)component condensation reaction: an unexpected approach for the synthesis of tetrahydro-2,4-dioxo-1H-benzo[b][1,5]diazepine-3-yl-2-methylpropanamide derivatives.Ahmad Shaabani et al.Organic letters, 11(15), 3342-3345 (2009-09-02) An energy efficient and facile synthesis of high molecular weight polyesters using ketenes.Martin Wolffs et al.Chemical communications (Cambridge, England), 47(38), 10572-10574 (2011-09-01) Polymer synthesis: facilitating functionality.Steve Rimmer Nature chemistry, 2(3), 164-165 (2010-12-03) A novel one-pot three-(in situ five-)component condensation reaction: an unexpected approach for the synthesis of tetrahydro-2,4-dioxo-1H-benzo[b][1,5]diazepine-3-yl-2-methylpropanamide derivatives.Ahmad Shaabani et al.Organic letters, 11(15), 3342-3345 (2009-09-02) An energy efficient and facile synthesis of high molecular weight polyesters using ketenes.Martin Wolffs et al.Chemical communications (Cambridge, England), 47(38), 10572-10574 (2011-09-01) Henning H-G, et al. Justus Liebigs Annalen der Chemie, 813-813 (1992) Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents.Harmeet S Sandhu et al.Bioorganic & medicinal chemistry, 18(15), 5626-5633 (2010-07-14) Probing persistent intramolecular C-H...X (X = O, S, Br, Cl, and F) bonding in solution using benzyl Meldrum's acid derivatives.Eric Fillion et al.The Journal of organic chemistry, 74(3), 1259-1267 (2008-12-31) New multicomponent domino reactions (MDRs) in water: highly chemo-, regio-and stereoselective synthesis of spiro {[1, 3] dioxanopyridine}-4, 6-diones and pyrazolo [3, 4-b] pyridines.Ma N, et al. Green Chemistry, 12?(8), 1357-1361 (2010) An efficient one-pot synthesis of pyrano[3,2-c]quinolin-2,5-dione derivatives catalyzed by L-proline.Songlei Zhu et al.Molecules (Basel, Switzerland), 17(12), 13856-13863 (2012-11-24) Microwave-assisted solid phase conversion study of Meldrum's acid to ethylenetetracarboxylic dianhydride (C6O6).Avat Arman Taherpour Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(1), 493-497 (2009-12-01) Electrochemical oxidation of catechols in the presence of phenyl-Meldrum's acid. Synthesis and kinetic evaluation.Davood Nematollahi et al.Chemical & pharmaceutical bulletin, 58(1), 23-26 (2010-01-05) The synthesis of β-keto lactones via cyclization of β-keto ester dianions or the cyclization of Meldrum's acid derivatives.Lermer L, et al. Canadian Journal of Chemistry, 70(5), 1427-1445 (1992) Synthetic routes to pyrrolizine-1,5-dione derivatives by flash vacuum pyrolysis of amidomethylene derivatives of Meldrum's acid.Hamish McNab et al.Organic & biomolecular chemistry, 7(23), 4936-4942 (2009-11-13) Selective synthesis of 3-hydroxy acids from Meldrum's acids using SmI2-H2O.Michal Szostak et al.Nature protocols, 7(5), 970-977 (2012-04-28) Meldrum's acids and 5-alkylidene Meldrum's acids in catalytic carbon-carbon bond-forming processes.Aaron M Dumas et al.Accounts of chemical research, 43(3), 440-454 (2009-12-17) A coumarin-Meldrum's acid conjugate based chemodosimetric probe for cyanide.Hongda Li et al.Chemical communications (Cambridge, England), 48(95), 11659-11661 (2012-10-26) A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.Jessica L Wojtaszek et al.Cell, 178(1), 152-159 (2019-06-11) Europium(III) functionalized 3D covalent organic framework for quinones adsorption and sensing investigation.Wen-Kui Li et al.Journal of hazardous materials, 388, 121740-121740 (2019-12-05) Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment.David Cantillo et al.The Journal of organic chemistry, 77(5), 2463-2473 (2012-02-11) A new domino autocatalytic reaction leading to polyfunctionalized spiro[5.5]undecanes and dispiro[4.2.5.2]pentadecanes.Bo Jiang et al.Organic & biomolecular chemistry, 7(10), 2195-2201 (2009-05-08) One hundred years of Meldrum's acid: advances in the synthesis of pyridine and pyrimidine derivatives.Victoria V Lipson et al.Molecular diversity, 13(4), 399-419 (2009-04-22) Synthesis of functionalized chromenes from Meldrum's acid, 4-hydroxycoumarin, and ketones or aldehydes.Maryam Sabbaghan et al.Combinatorial chemistry & high throughput screening, 13(9), 813-817 (2010-07-10) Pseudo-five-component reaction between 3-formylchromones, meldrum's acid, isocyanides and primary arylamines: diversity-oriented synthesis of novel chromone-containing peptidomimetics.Mohammad Bagher Teimouri et al.ACS combinatorial science, 13(6), 659-666 (2011-09-17)

Remarks