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Antioxidant 425 | CAS:88-24-4
Antioxidant 425
  • Name:Antioxidant 425
  • CAS:88-24-4
  • Synonyms:2,2'-Methylenebis(4-ethyl-6-tert-butylphenol); 6,6'-Di-tert-butyl-4,4'-diethyl-2,2'-methylenediphenol
  • Molecular Formula:C25H36O2
  • Molecular Weight:368.55
  • EINESC:201-814-0

Description

Properties

Melting point 119-122 ºC
Density 1.010

Safety

Symbol(GHS) Xi
Hazard Codes R36/37/38
SDS/MSDS S26;S36

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
The methoxylated flavones eupatorin and cirsiliol induce CYP1 enzyme expression in MCF7 cells.Vasilis P Androutsopoulos et al.Journal of natural products, 72(8), 1390-1394 (2009-07-16) Analysis of vervain flavonoids by HPLC/Diode array detector method. Its application to quality control.P Valentão et al.Journal of agricultural and food chemistry, 47(11), 4579-4582 (1999-12-20) Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves.Iva Dolečková et al.Fitoterapia, 83(6), 1000-1007 (2012-06-16) Determination of flavonoids from Orthosiphon stamineus in plasma using a simple HPLC method with ultraviolet detection.Yit Hong Loon et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 816(1-2), 161-166 (2005-01-25) Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation.Mirka Laavola et al.Planta medica, 78(8), 779-786 (2012-04-21) Eupatorin Suppressed Tumor Progression and Enhanced Immunity in a 4T1 Murine Breast Cancer Model.Nursyamirah Abd Razak et al.Integrative cancer therapies, 19, 1534735420935625-1534735420935625 (2020-08-25) In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19).Yan Pan et al.Journal of ethnopharmacology, 133(2), 881-887 (2010-11-26) Lipophilic flavonoids from Orthosiphon spicatus prevent oxidative inactivation of 15-lipoxygenase.I M Lyckander et al.Prostaglandins, leukotrienes, and essential fatty acids, 54(4), 239-246 (1996-04-01) The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis.Anna-Leena Salmela et al.Experimental cell research, 318(5), 578-592 (2012-01-10) Flavones and rosmarinic acid from Salvia limbata.Ahmad R Gohari et al.Natural product research, 24(20), 1902-1906 (2010-11-26) Bioactive Phenolics of the Genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS/MS Profile of the Siberian Species and Their Inhibitory Potential AgainstOlennikov DN, et al. Frontiers in Pharmacology, 9 (2018) A simple isocratic HPLC method for the simultaneous determination of sinensetin, eupatorin, and 3'-hydroxy-5,6,7,4'-tetramethoxyflavone in Orthosiphon stamineus extracts.Mun Fei Yam et al.Journal of acupuncture and meridian studies, 5(4), 176-182 (2012-08-18)
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