Melting point	299-305 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
Sigma-Aldrich	View & Download
TCI	View & Download
Oakwood	View & Download

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Effect of organic cosolvent on kinetic resolution of tert-leucine by penicillin G acylase from Kluyvera citrophila.Shu-Lai Liu et al.Bioprocess and biosystems engineering, 28(5), 285-289 (2005-10-26) Highly selective asymmetric acetate aldol reactions of an N-acetyl thiazolidinethione reagent.Yingchao Zhang et al.Organic letters, 6(1), 23-25 (2004-01-03) Enzyme-assisted preparation of D-tert.-leucine.K Laumen et al.Bioscience, biotechnology, and biochemistry, 65(9), 1977-1980 (2001-10-26) Preparation of (S)?tert?Butyl PHOX: (Oxazole, 4?(1, 1?Dimethylethyl)?2?[2?(Diphenylphosphino) Phenyl]?4, 5?Dihydro?(4S)?).Krout M R, et al. Organic Syntheses, 86, 181-193 (2003) An efficient and selective enzymatic oxidation system for the synthesis of enantiomerically pure D-tert-leucine.Werner Hummel et al.Organic letters, 5(20), 3649-3650 (2003-09-26) Scaleable catalytic asymmetric Strecker syntheses of unnatural alpha-amino acids.Stephan J Zuend et al.Nature, 461(7266), 968-970 (2009-10-16) Preferred conformations of peptides containing tert-leucine, a sterically demanding, lipophilic alpha-amino acid with a quaternary side-chain Cbeta atom.Fernando Formaggio et al.Chemistry (Weinheim an der Bergstrasse, Germany), 11(8), 2395-2404 (2005-01-26) Synthesis, structure and application of chiral copper (II) coordination polymers for asymmetric acylation.Jammi S, et al. Inorganic Chemistry, 47(12), 5093-5098 (2008) Highly Selective Asymmetric Acetate Aldol Reactions of an N-Acetyl Thiazolidinethione Reagent.Zhang Y, et al. Organic Letters, 6(1), 23-25 (2004) Asymmetric construction of spirocyclohexanonerhodanines catalyzed by simple diamine derived from chiral tert-leucine.Wenbin Wu et al.Chemical communications (Cambridge, England), 48(73), 9180-9182 (2012-08-07) Stabilizing and destabilizing effects of placing beta-branched amino acids in protein alpha-helices.V W Cornish et al.Biochemistry, 33(40), 12022-12031 (1994-10-11) The tert-butyl group in chemistry and biology.Philippe Bisel et al.Organic & biomolecular chemistry, 6(15), 2655-2665 (2008-07-18) Use of unprotected amino acids in metal-free tandem radical cyclization reactions: divergent synthesis of 6-alkyl/acyl phenanthridines.Lu S C, et al. Royal Society of Chemistry Advances, 7(88), 55891-55896 (2017)

Remarks