Melting point	68-71 ºC
Density	1.28

SDS/MSDS	S24/25

Source	SDS/MSDS Samples
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Synthetic Route

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Peer-Reviewed Papers

Effects of acute pinitol supplementation on plasma pinitol concentration, whole body glucose tolerance, and activation of the skeletal muscle insulin receptor in older humans.A J Stull et al.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 41(5), 381-386 (2009-02-18) Antihepatotoxic activity of a quantified Desmodium adscendens decoction and D-pinitol against chemically-induced liver damage in rats.Joanna Magielse et al.Journal of ethnopharmacology, 146(1), 250-256 (2013-01-08) The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals.Prashant Singh Chauhan et al.International immunopharmacology, 11(2), 286-291 (2010-12-16) Determination of D-pinitol in carob syrup.Nedim Tetik et al.International journal of food sciences and nutrition, 62(6), 572-576 (2011-04-07) Efficient synthetic routes to fluorinated isosteres of inositol and their effects on cellular growth.Kozikowski AP, et al. Journal of the American Chemical Society, 112(11), 4528-4531 (1990) A single acute dose of pinitol from a naturally-occurring food ingredient decreases hyperglycaemia and circulating insulin levels in healthy subjects.Antonio Hernández-Mijares et al.Food chemistry, 141(2), 1267-1272 (2013-06-26) Metabolic response of soy pinitol on lipid-lowering, antioxidant and hepatoprotective action in hamsters fed-high fat and high cholesterol diet.Myung-Sook Choi et al.Molecular nutrition & food research, 53(6), 751-759 (2009-02-11) Protective effect of pinitol against D-galactosamine-induced hepatotoxicity in rats fed on a high-fat diet.Yusi Zhou et al.Bioscience, biotechnology, and biochemistry, 72(7), 1657-1666 (2008-07-08) Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats.Selvaraj Sivakumar et al.Chemico-biological interactions, 188(1), 237-245 (2010-07-21) Semi-synthetic analogs of pinitol as potential inhibitors of TNF-alpha cytokine expression in human neutrophils.Khurshid A Bhat et al.Bioorganic & medicinal chemistry letters, 19(7), 1939-1943 (2009-03-10) Effects of pinitol on glycemic control, insulin resistance and adipocytokine levels in patients with type 2 diabetes mellitus.Hyun Jin Kim et al.Annals of nutrition & metabolism, 60(1), 1-5 (2011-12-20) Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism.Adrienne C Müller et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 15(2), 221-233 (2012-05-15) Narayanan, C.R. et al. Current Science, 56, 139-139 (1987) Kozikowski, A.P. et al. Journal of the American Chemical Society, 112, 4528-4528 (1990) D-pinitol attenuates the impaired activities of hepatic key enzymes in carbohydrate metabolism of streptozotocin-induced diabetic rats.Selvaraj Sivakumar et al.General physiology and biophysics, 28(3), 233-241 (2009-12-29) D-chiro-inositol and pinitol extend the life span of Drosophila melanogaster.Binika Hada et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 68(3), 226-234 (2012-07-31) D-(+)-pinitol, a component of the heartwood of Enterolobium cyclocarpum (Jacq.) Griseb.David Raya-Gonzalez et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(11-12), 922-924 (2009-02-21) Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats.Selvaraj Sivakumar et al.European journal of pharmacology, 622(1-3), 65-70 (2009-09-22) Antihyperglycemic activity of extracts from Boldoa purpurascens leaves in alloxan-induced diabetic rats.D M González Mosquera et al.Phytotherapy research : PTR, 27(5), 721-724 (2012-07-19) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae).Angel Josabad Alonso-Castro et al.Journal of ethnopharmacology, 224, 314-322 (2018-06-19) D-Pinitol attenuates 7, 12 dimethylbenz [a] anthracene induced hazards through modulating protein bound carbohydrates, adenosine triphosphatases and lysosomal enzymes during experimental mammary carcinogenesis.Thamaraiselvan Rengarajan et al.Journal of experimental therapeutics & oncology, 10(1), 39-49 (2012-09-06) Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats.Selvaraj Sivakumar et al.Free radical research, 44(6), 668-678 (2010-04-08) The effects of creatine monohydrate supplementation with and without D-pinitol on resistance training adaptations.Chad M Kerksick et al.Journal of strength and conditioning research, 23(9), 2673-2682 (2009-10-28) Salt Stress Perception and Plant Growth Regulators in the Halophyte Mesembryanthemum crystallinum.J. C. Thomas et al.Plant physiology, 103(4), 1299-1304 (1993-12-01) Synthesis of azole nucleoside analogues of D-pinitol as potential antitumor agents.Zhan T and Lou H. Carbohydrate Research, 342(6), 865-869 (2007) Different sodium salts cause different solute accumulation in the halophyte Prosopis strombulifera.A Llanes et al.Plant biology (Stuttgart, Germany), 15 Suppl 1, 118-125 (2012-07-04) Inositol methyl tranferase from a halophytic wild rice, Porteresia coarctata Roxb. (Tateoka): regulation of pinitol synthesis under abiotic stress.Sonali Sengupta et al.Plant, cell & environment, 31(10), 1442-1459 (2008-07-23) D-pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice.Nhung Thuy Dang et al.Bioscience, biotechnology, and biochemistry, 74(5), 1062-1067 (2010-05-13) D-pinitol inhibits RANKL-induced osteoclastogenesis.Shan-Chi Liu et al.International immunopharmacology, 12(3), 494-500 (2012-01-25) D-chiro-inositol affects accumulation of raffinose family oligosaccharides in developing embryos of Pisum sativum.Lesław B Lahuta et al.Journal of plant physiology, 168(4), 352-358 (2010-10-16) Antihyperlipidemic effect of D-pinitol on streptozotocin-induced diabetic Wistar rats.P K M Anu Geethan et al.Journal of biochemical and molecular toxicology, 22(4), 220-224 (2008-08-30) Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.Gautam Sethi et al.Molecular cancer therapeutics, 7(6), 1604-1614 (2008-06-21)

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