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Synthetic Route

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Peer-Reviewed Papers

Chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the down-regulation of NF-kappaB DNA binding activity.Seung Hyun Kim et al.The Journal of biological chemistry, 281(19), 13117-13125 (2006-03-24) [Enterobiasis in pediatric subjects in north-western Italy: a study of home remedies].M Dutto et al.Annali di igiene : medicina preventiva e di comunita, 24(1), 81-84 (2012-06-08) Expanding the repertoire of small molecule transcriptional activation domains.Ryan J Casey et al.Bioorganic & medicinal chemistry, 17(3), 1034-1043 (2008-03-13) Diminutive effect on T and B-cell proliferation of non-cytotoxic α-santonin derived 1,2,3-triazoles: a report.Praveen K Chinthakindi et al.European journal of medicinal chemistry, 60, 365-375 (2013-01-15) Role of the 3(ππ*) state in photolysis of lumisantonin: insight from ab initio studies.Xing Chen et al.The journal of physical chemistry. A, 115(26), 7815-7822 (2011-06-02) Biotransformation of 6beta-santonin by Phytolacca acinosa cell suspension cultures.Lin Yang et al.Yao xue xue bao = Acta pharmaceutica Sinica, 40(9), 834-837 (2005-12-14) Structure-based pharmacophore screening for natural-product-derived PPARgamma agonists.Yusuf Tanrikulu et al.Chembiochem : a European journal of chemical biology, 10(1), 75-78 (2008-12-11) Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones.Oné R Pagán et al.Pharmacology, biochemistry, and behavior, 89(2), 160-170 (2008-01-29) Synthesis of diacetoxy acetal derivatives of santonin and their enhancing effects on HL-60 leukemia cell differentiation.Seung Hyun Kim et al.Archives of pharmacal research, 29(1), 40-45 (2006-02-24) Natural products in parallel chemistry--novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from alpha-santonin.Oliver Schwarz et al.Journal of combinatorial chemistry, 9(6), 1104-1113 (2007-09-14) Biotransformation of tetrahydro-alpha-santonins by Absidia coerulea.Lin Yang et al.Natural product research, 22(6), 499-506 (2008-04-17) The stories of santonin and santonic acid.Ludmila Birladeanu Angewandte Chemie (International ed. in English), 42(11), 1202-1208 (2003-03-20) Biotransformation of alpha-santonin by cell suspension cultures of five plants.Lin Yang et al.Biotechnology letters, 27(11), 793-797 (2005-08-09) Synthesis and cytotoxic activity of alpha-santonin derivatives.Francisco F P Arantes et al.European journal of medicinal chemistry, 44(9), 3739-3745 (2009-05-02) Synthesis of DAAS derivatives and their enhancement of HL-60 leukemia cell differentiation.Seung Hyun Kim et al.Archives of pharmacal research, 31(3), 300-304 (2008-04-15) [History of the Nippon Shinyaku Institute for Botanical Research].Takao Yamaura Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(3), 395-400 (2011-03-05) Microbial transformations of alpha-santonin.Athar Ata et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(3-4), 209-214 (2004-07-10) Theoretical studies on the photoinduced rearrangement mechanism of α-santonin.Xing Chen et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 13(1), 353-362 (2011-11-29) Biotransformation of alpha- and 6beta-santonin by fungus and plant cell cultures.L Yang et al.Journal of Asian natural products research, 8(4), 317-326 (2006-07-26) Synthesis of novel α-santonin derivatives as potential cytotoxic agents.Francisco F P Arantes et al.European journal of medicinal chemistry, 45(12), 6045-6051 (2010-10-26) Amelioration of root-knot disease of lady's finger plants by potentized Cina and Santonin.N C Sukul et al.Homeopathy : the journal of the Faculty of Homeopathy, 95(3), 144-147 (2006-07-04) The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.Stephan Born et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(1), 201-213 (2013-01-04) Synthesis of C (6)-epimer derivatives of diacetoxy acetal derivative of santonin and their inducing effects on HL-60 leukemia cell differentiation.Sin Ho Kweon et al.Archives of pharmacal research, 34(2), 191-198 (2011-03-08) Santonin-related compound 2 inhibits the nuclear translocation of NF-κB subunit p65 by targeting cysteine 38 in TNF-α-induced NF-κB signaling pathway.Ryuichi Tamura et al.Bioscience, biotechnology, and biochemistry, 76(12), 2360-2363 (2012-12-12) Synthesis of Spirovetivane Sesquiterpenes from Santonin. Synthesis of (+)-Anhydro-beta-rotunol and all diastereomers of 6,11-spirovetivadiene.Gonzalo Blay et al.The Journal of organic chemistry, 69(21), 7294-7302 (2004-10-09) Pursuing structure in microcrystalline solids with independent molecules in the unit cell using 1H-13C correlation data.James K Harper et al.Journal of magnetic resonance (San Diego, Calif. : 1997), 189(1), 20-31 (2007-09-18)

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