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L(-)-Malic acid | CAS:97-67-6
L(-)-Malic acid
  • Name:L(-)-Malic acid
  • CAS:97-67-6
  • Synonyms:L-Hydroxysuccinic acid; Apple acid
  • Molecular Formula:C4H6O5
  • Molecular Weight:134.08
  • EINESC:202-601-5

Description

Properties

Melting point 101-103 ºC
Specific optical rotation -2 º (c=8.5, H2O)
Water Solubility soluble

Safety

Symbol(GHS) Xi
Hazard Codes R36/37/38
SDS/MSDS S26;S37/39

SDS

Source SDS/MSDS Samples
没有数据没有数据
Synthetic Route
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Articles
Peer-Reviewed Papers
Catalytic Biosensors from Complex Coacervate Core Micelle (C3M) Thin Films.Hursh V Sureka et al.ACS applied materials & interfaces, 11(35), 32354-32365 (2019-08-24) Reduction of Allergenic Potential in Bread Wheat RNAi Transgenic Lines Silenced for CM3, CM16 and 0.28ATI Genes.Raviraj M Kalunke et al.International journal of molecular sciences, 21(16) (2020-08-23) Enhanced osteogenesis of quasi-three-dimensional hierarchical topography.Mengfei Yu et al.Journal of nanobiotechnology, 17(1), 102-102 (2019-10-05) Defining a turnover index for the correlation of biomaterial degradation and cell based extracellular matrix synthesis using fluorescent tagging techniques.Katie Bardsley et al.Acta biomaterialia, 45, 133-142 (2016-10-19) Hybrid flagellin as a T cell independent vaccine scaffold.Kaila M Bennett et al.BMC biotechnology, 15, 71-71 (2015-08-13) The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.Endang R Purba et al.Drug metabolism and pharmacokinetics, 30(1), 75-81 (2015-03-12) Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics.Francis Aguisanda et al.Orphanet journal of rare diseases, 12(1), 120-120 (2017-07-01) Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease.Suzanne M de la Monte et al.Journal of Alzheimer's disease : JAD, 55(2), 849-864 (2016-11-02) Polyelectrolyte multi-layers assembly of SiCHA nanopowders and collagen type I on aminolysed PLA films to enhance cell-material interactions.Yanny Marliana Baba Ismail et al.Colloids and surfaces. B, Biointerfaces, 159, 445-453 (2017-08-25) Aptamer-based detection of disease biomarkers in mouse models for chagas drug discovery.Fernanda Fortes de Araujo et al.PLoS neglected tropical diseases, 9(1), e3451-e3451 (2015-01-09) Evaluation of Hydra HALT-1 as a toxin moiety for recombinant immunotoxin.William F Jiemy et al.BMC biotechnology, 20(1), 31-31 (2020-06-20) Injectable Alginate-Peptide Composite Hydrogel as a Scaffold for Bone Tissue Regeneration.Moumita Ghosh et al.Nanomaterials (Basel, Switzerland), 9(4) (2019-04-04) Electrospun polymer scaffolds modified with drugs for tissue engineering.Izabella Rajzer et al.Materials science & engineering. C, Materials for biological applications, 77, 493-499 (2017-05-24) A novel nanoluciferase-based system to monitor Trypanosoma cruzi infection in mice by bioluminescence imaging.Erica Silberstein et al.PloS one, 13(4), e0195879-e0195879 (2018-04-20) M cell targeting by a Claudin 4 targeting peptide can enhance mucosal IgA responses.David D Lo et al.BMC biotechnology, 12, 7-7 (2012-03-15) A multi-material coating containing chemically-modified apatites for combined enhanced bioactivity and reduced infection via a drop-on-demand micro-dispensing technique.Poon Nian Lim et al.Journal of materials science. Materials in medicine, 28(1), 3-3 (2016-11-24) Molecular and Functional Phenotypes of Human Bone Marrow-Derived Mesenchymal Stromal Cells Depend on Harvesting Techniques.Sebastian G Walter et al.International journal of molecular sciences, 21(12) (2020-06-25) Role of surface chemistry in protein remodeling at the cell-material interface.Virginia Llopis-Hernández et al.PloS one, 6(5), e19610-e19610 (2011-05-17) A single-molecule digital enzyme assay using alkaline phosphatase with a cumarin-based fluorogenic substrate.Yusuke Obayashi et al.The Analyst, 140(15), 5065-5073 (2015-06-24) Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins.Giulia Pavani et al.Nature communications, 11(1), 3778-3778 (2020-07-31) Highly sensitive chemiluminescent sensing of intracellular Al3+ based on the phosphatase mimetic activity of cerium oxide nanoparticles.Xue Tian et al.Biosensors & bioelectronics, 152, 112027-112027 (2020-02-15) Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection.Lucia A de Oliveira Fraga et al.BMC immunology, 11, 56-56 (2010-11-17) Age-related neurochemical and behavioural changes in D409V/WT GBA1 mouse: Relevance to lewy body dementia.E Clarke et al.Neurochemistry international, 129, 104502-104502 (2019-07-13) Tobacco Smoke Exposure Impairs Brain Insulin/IGF Signaling: Potential Co-Factor Role in Neurodegeneration.Chetram Deochand et al.Journal of Alzheimer's disease : JAD, 50(2), 373-386 (2015-12-20) A cellular high-throughput screening approach for therapeutic trans-cleaving ribozymes and RNAi against arbitrary mRNA disease targets.Edwin H Yau et al.Experimental eye research, 151, 236-255 (2016-05-29) Differential Contributions of Alcohol and the Nicotine-Derived Nitrosamine Ketone (NNK) to Insulin and Insulin-Like Growth Factor Resistance in the Adolescent Rat Brain.Ming Tong et al.Alcohol and alcoholism (Oxford, Oxfordshire), 50(6), 670-679 (2015-09-17) Fluorescence enhancement aided by metal ion displacement.Vanessa Susini et al.Biosensors & bioelectronics, 80, 237-242 (2016-02-07) Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial.Rubhana Raqib et al.BMC infectious diseases, 12, 111-111 (2012-05-12) Surface hydroxyl groups direct cellular response on amorphous and anatase TiO2 nanodots.Yi Hong et al.Colloids and surfaces. B, Biointerfaces, 123, 68-74 (2014-09-13) Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates.Matthew G Haugh et al.Biomaterials, 171, 23-33 (2018-04-21) Application of intracellular alkaline phosphatase activity measurement in detection of neutrophil adherence in vitro.Katarzyna Bednarska et al.Mediators of inflammation, 2006(4), 19307-19307 (2006-10-19) Nanoscale Coatings for Ultralow Dose BMP-2-Driven Regeneration of Critical-Sized Bone Defects.Zhe A Cheng et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(2), 1800361-1800361 (2019-01-30) T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.Ming Tong et al.Journal of Alzheimer's disease : JAD, 51(1), 123-138 (2016-02-03) Exogenous noggin binds the BMP-2 receptor and induces alkaline phosphatase activity in osteoblasts.Saeed M Hashimi Journal of cellular biochemistry, 120(8), 13237-13242 (2019-03-20) Role of material-driven fibronectin fibrillogenesis in protein remodeling.Virginia Llopis-Hernández et al.BioResearch open access, 2(5), 364-373 (2013-10-02) Sequential release of nanoparticle payloads from ultrasonically burstable capsules.Stephen Kennedy et al.Biomaterials, 75, 91-101 (2015-10-27) The cellular magnetic response and biocompatibility of biogenic zinc- and cobalt-doped magnetite nanoparticles.Sandhya Moise et al.Scientific reports, 7, 39922-39922 (2017-01-04) β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.Lauren M Slosky et al.Cell, 181(6), 1364-1379 (2020-05-30) Identification of a target protein of Hydra actinoporin-like toxin-1 (HALT-1) using GST affinity purification and SILAC-based quantitative proteomics.Ameirika et al.Toxicon : official journal of the International Society on Toxinology, 133, 153-161 (2017-05-10)
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