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3-Trifluoromethylphenol | CAS:98-17-9
3-Trifluoromethylphenol
  • Name:3-Trifluoromethylphenol
  • CAS:98-17-9
  • Synonyms:m-Hydroxybenzotrifluoride; 3-Hydroxybenzotrifluoride; 3-(Trifluoromethyl)phenol; alpha,alpha,alpha-Trifluoro-m-cresol
  • Molecular Formula:C7H5F3O
  • Molecular Weight:162.11
  • EINESC:202-645-5

Description

Properties

Melting point -1.8 ºC
Water Solubility Insoluble
Boiling point 178-179 ºC
Flash point 73 ºC
Density 1.333
Refractive index 1.457-1.459

Safety

Symbol(GHS) T;Xi
Hazard Codes R24/25;R34;R37/38;R41
SDS/MSDS S26;S36/37/39;S45

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Metabolism of biphenyl by Aspergillus toxicarius: induction of hydroxylating activity and accumulation of water-soluble conjugates.J H Golbeck et al.Journal of bacteriology, 156(1), 49-57 (1983-10-01) Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4'-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human breast cancer cell line MCF-7.Christel M Olsen et al.Pharmacology & toxicology, 92(4), 180-188 (2003-05-20) Inhibition of melanogenic activity by 4,4'-dihydroxybiphenyl in melanoma cells.Jae Kyung No et al.Biological & pharmaceutical bulletin, 29(1), 14-16 (2006-01-06) Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth.Rainer-B Volk et al.Microbiological research, 161(2), 180-186 (2006-01-24) Antioxidant and cyclooxygenase-2-inhibiting activity of 4,4'-biphenol, 2,2'-biphenol and phenol.Yukio Murakami et al.Anticancer research, 29(6), 2403-2410 (2009-06-17) Lignan compounds and 4,4'-dihydroxybiphenyl protect C2C12 cells against damage from oxidative stress.Ayumu Yoshikawa et al.Biochemical and biophysical research communications, 344(1), 394-399 (2006-04-18) 4,4'-Dihydroxybiphenyl as a new potent tyrosinase inhibitor.You Jung Kim et al.Biological & pharmaceutical bulletin, 28(2), 323-327 (2005-02-03) Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp.Nelson H Caicedo et al.Marine biotechnology (New York, N.Y.), 14(4), 436-445 (2011-12-14) Kinetic evaluation of reactivity of bisphenol A derivatives as radical scavengers for methacrylate polymerization.Y Kadoma et al.Biomaterials, 21(21), 2125-2130 (2000-09-14) Hydroxylations of biphenyl by fungi.R V Smith et al.The Journal of applied bacteriology, 49(1), 65-73 (1980-08-01) Self-assembly and host-guest chemistry of a 3.5-nm coordination nanotube.Takumi Yamaguchi et al.Chemistry, an Asian journal, 2(4), 468-476 (2007-04-19) Occupational dermatitis to dihydroxydiphenyl and diphenylthiourea in neoprene gloves.M L Masmoudi et al.Contact dermatitis, 16(5), 290-291 (1987-05-01) Peroxidase-catalyzed-3-(glutathion-S-yl)-p,p'-biphenol formation.L G McGirr et al.Chemico-biological interactions, 60(1), 85-99 (1986-10-15) Constituents of Agaricus xanthodermus Genevier: the first naturally endogenous azo compound and toxic phenolic metabolites.M Gill et al.Zeitschrift fur Naturforschung. Section C, Biosciences, 39(11-12), 1027-1029 (1984-11-01) Angewandte Chemie (International Edition in English), 106, 1563-1563 (1994) Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists.Miriam Schöpel et al.Journal of medicinal chemistry, 56(23), 9664-9672 (2013-11-26)
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