Melting point	31-34 ºC
Water Solubility	negligible
Boiling point	214-224 ºC
Flash point	90 ºC
Density	0.936
Refractive index	1.482-1.485

Symbol(GHS)	Xi
Hazard Codes	R38
SDS/MSDS	S37

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Determination of hyperin in seed of Cuscuta chinensis Lam. by enhanced chemiluminescence of CdTe quantum dots on calcein/K3Fe(CN)6 system.Jing Kang et al.Food chemistry, 134(4), 2383-2388 (2013-02-28) An ethyl acetate fraction derived from Houttuynia cordata extract inhibits the production of inflammatory markers by suppressing NF-кB and MAPK activation in lipopolysaccharide-stimulated RAW 264.7 macrophages.Jin Mi Chun et al.BMC complementary and alternative medicine, 14, 234-234 (2014-07-12) [Studies on the chemical constituents of the herb of Antenoron filiforme].You-Xing Zhao et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 704-707 (2011-10-01) Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds.Nicole Schöbel et al.Chemical senses, 39(6), 471-487 (2014-04-11) Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside.Sae-Kwang Ku et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 197-204 (2012-12-12) New Polyphenols Identified in Artemisiae abrotani herba Extract.Elisabeta Baiceanu et al.Molecules (Basel, Switzerland), 20(6), 11063-11075 (2015-06-18) Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents.Abugafar M L Hossion et al.Journal of medicinal chemistry, 54(11), 3686-3703 (2011-05-04) Simultaneous determination of 14 constituents of Radix polygoni multiflori from different geographical areas by liquid chromatography-tandem mass spectrometry.Longfei Lin et al.Biomedical chromatography : BMC, 29(7), 1048-1055 (2014-12-03) Anti-inflammatory effects of hyperoside in human endothelial cells and in mice.Sae-Kwang Ku et al.Inflammation, 38(2), 784-799 (2014-08-07) Biological and Chemical Insights of Beech (Fagus sylvatica L.) Bark: A Source of Bioactive Compounds with Functional Properties.Corneliu Tanase et al.Antioxidants (Basel, Switzerland), 8(9) (2019-09-25) Induction of Nur77 by hyperoside inhibits vascular smooth muscle cell proliferation and neointimal formation.Yan Huo et al.Biochemical pharmacology, 92(4), 590-598 (2014-10-16) Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance.Cassandra L Quave et al.PloS one, 10(8), e0136486-e0136486 (2015-08-22) Phytochemical Characterization of Veronica officinalis L., V. teucrium L. and V. orchidea Crantz from Romania and Their Antioxidant and Antimicrobial Properties.Andrei Mocan et al.International journal of molecular sciences, 16(9), 21109-21127 (2015-09-26) [Chemical constituents of flavonoids from flowers of Koelreuteria paniculata].Qing-Hui Qu et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(11), 1716-1719 (2012-04-18) Quantitative determination of phenolic compounds in lotus (Nelumbo nucifera) leaves by capillary zone electrophoresis.Tho Chau Minh Vinh Do et al.Planta medica, 78(16), 1796-1799 (2012-08-28) Highly sensitive analysis of flavonoids by zwitterionic microemulsion electrokinetic chromatography coupled with light-emitting diode-induced fluorescence detection.Wan Cao et al.Journal of chromatography. A, 1358, 277-284 (2014-07-23) Microemulsion liquid chromatographic method for simultaneous separation and determination of six flavonoids of Apocynum venetum leaf extract.Rui juan Song et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 995-996, 8-14 (2015-05-30) Pretreatment with the total flavone glycosides of Flos Abelmoschus manihot and hyperoside prevents glomerular podocyte apoptosis in streptozotocin-induced diabetic nephropathy.Lei Zhou et al.Journal of medicinal food, 15(5), 461-468 (2012-03-24) Identification of common horsetail (Equisetum arvense L.; Equisetaceae) using Thin Layer Chromatography versus DNA barcoding.C Haris Saslis-Lagoudakis et al.Scientific reports, 5, 11942-11942 (2015-07-15) Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift reactor.Xi-Hua Cui et al.Bioresource technology, 102(21), 10072-10079 (2011-09-16) Anticonvulsant, antidepressant-like activity of Abelmoschus manihot ethanol extract and its potential active components in vivo.Jianming Guo et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(14), 1250-1254 (2011-07-26) The effects of Zanthoxylum bungeanum extract on lipid metabolism induced by sterols.Tingting Wu et al.Journal of pharmacological sciences, 127(3), 251-259 (2015-04-04) Comparative Studies on Polyphenolic Composition, Antioxidant and Diuretic Effects of Nigella sativa L. (Black Cumin) and Nigella damascena L. (Lady-in-a-Mist) Seeds.Claudia-Crina Toma et al.Molecules (Basel, Switzerland), 20(6), 9560-9574 (2015-05-29) Hyperin extracted from Manchurian rhododendron leaf induces apoptosis in human endometrial cancer cells through a mitochondrial pathway.Fu-Rong Li et al.Asian Pacific journal of cancer prevention : APJCP, 13(8), 3653-3656 (2012-10-27) The antibiofilm activity of lingonberry flavonoids against oral pathogens is a case connected to residual complexity.Kaisu R Riihinen et al.Fitoterapia, 97, 78-86 (2014-06-01) [Analysis of fingerprint and bioactive components of Bidens biternata by HPLC].Tao-Tao Ma et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(6), 892-896 (2012-12-15) Analysis of Flavonoids in Lotus (Nelumbo nucifera) Leaves and Their Antioxidant Activity Using Macroporous Resin Chromatography Coupled with LC-MS/MS and Antioxidant Biochemical Assays.Ming-Zhi Zhu et al.Molecules (Basel, Switzerland), 20(6), 10553-10565 (2015-06-11) Phytochemical analysis and in vitro biological activity of three Hypericum species from the Canary Islands (Hypericum reflexum, Hypericum canariense and Hypericum grandifolium).Christian Zorzetto et al.Fitoterapia, 100, 95-109 (2014-12-03) Phytochemical composition, antioxidant activity and HPLC fingerprinting profiles of three Pyrola species from different regions.Dongmei Wang et al.PloS one, 9(5), e96329-e96329 (2014-05-07) ILs-based microwave-assisted extraction coupled with aqueous two-phase for the extraction of useful compounds from Chinese medicine.Xiao Lin et al.The Analyst, 137(17), 4076-4085 (2012-07-13) A high performance liquid chromatography with ultraviolet method for Eschweilera nana leaves and their anti-inflammatory and antioxidant activities.Priscila M Outuki et al.Pharmacognosy magazine, 11(43), 619-626 (2015-08-08) [Protective effects and mechanism of hyperin on CoCl2-induced PC12 cells].Kewu Zeng et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(17), 2409-2412 (2011-11-30) Quantification of chlorogenic acid and hyperoside directly from crude blueberry (Vaccinium angustifolium) leaf extract by NMR spectroscopy analysis: single-laboratory validation.Joshua M Hicks et al.Journal of AOAC International, 95(5), 1406-1411 (2012-11-28) Chlorogenic acid, rutin and hyperoside content in Fragaria vesca, F. viridis and F. moschata in Lithuania.Edita Bagdonaite et al.Natural product research, 27(2), 181-184 (2012-02-14) Protective effects of hyperoside against human umbilical vein endothelial cell damage induced by hydrogen peroxide.Zi-lin Li et al.Journal of ethnopharmacology, 139(2), 388-394 (2011-11-29) In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus.Andrea Civra et al.BMC complementary and alternative medicine, 17(1), 74-74 (2017-01-26) Hyperin and quercetin modulate oxidative stress-induced melanogenesis.You Jung Kim Biological & pharmaceutical bulletin, 35(11), 2023-2027 (2012-09-14) Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway.Ke-Wu Zeng et al.European journal of pharmacology, 672(1-3), 45-55 (2011-10-08) Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.Giancarlo Statti et al.Phytotherapy research : PTR, 29(6), 857-863 (2015-03-11) The effect of hyperoside on the functional recovery of the ischemic/reperfused isolated rat heart: potential involvement of the extracellular signal-regulated kinase 1/2 signaling pathway.Zi-lin Li et al.Free radical biology & medicine, 57, 132-140 (2013-01-08) Determination of hyperoside and isoquercitrin in rat plasma by membrane-protected micro-solid-phase extraction with high-performance liquid chromatography.Xiao-Ying Yin et al.Journal of separation science, 35(3), 384-391 (2012-01-20) [Absorption of flavonoids from Abelmoschus manihot extract by in situ intestinal perfusion].Cai-fu Xue et al.Yao xue xue bao = Acta pharmaceutica Sinica, 46(4), 454-459 (2011-07-15) Antidepressant-like effect of hyperoside isolated from Apocynum venetum leaves: possible cellular mechanisms.Meizhu Zheng et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(2), 145-149 (2011-08-02) Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach.Hui Cao et al.Food chemistry, 270, 257-263 (2018-09-04) [Study on toxicity of hyperoside in rat embryo-fetal development].Guo Ai et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(16), 2452-2455 (2012-12-14) Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo.Sae-Kwang Ku et al.Inflammation, 37(5), 1389-1400 (2014-03-13) Application of microdialysis for elucidating the existing form of hyperoside in rat brain: comparison between intragastric and intraperitoneal administration.Jian-ming Guo et al.Journal of ethnopharmacology, 144(3), 664-670 (2012-10-16) Protective effects of polyphenols-enriched extract from Huangshan Maofeng green tea against CCl4-induced liver injury in mice.Yanmang Cui et al.Chemico-biological interactions, 220, 75-83 (2014-06-29) Rosa canina L.--new possibilities for an old medicinal herb.Jelena Živković et al.Food & function, 6(12), 3687-3692 (2015-09-25) Pharmacological evaluation of hyperin for antihyperglycemic activity and effect on lipid profile in diabetic rats.Neeraj Verma et al.Indian journal of experimental biology, 51(1), 65-72 (2013-02-28) Hyperoside protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via nitric oxide signal pathway.Rui-Li Liu et al.Brain research, 1469, 164-173 (2012-07-10)

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