Melting point	179-182 ºC
Boiling point	274-275 ºC

Symbol(GHS)	Xn
Hazard Codes	R22
SDS/MSDS	S22

Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

Synthesis and free radical scavenging activity of some new spiropyranocoumarins.Vassiliki Panteleon et al.Bioorganic & medicinal chemistry letters, 18(21), 5781-5784 (2008-10-07) Reversible two-photon optical data storage in coumarin-based copolymers.Iliopoulos K, et al. Journal of the American Chemical Society, 132(41), 14343-14345 (2010) Synthesis and anti-inflammatory effects of a series of novel 7-hydroxycoumarin derivatives.Juri M Timonen et al.European journal of medicinal chemistry, 46(9), 3845-3850 (2011-06-18) An integrated strategy based on UPLC-DAD-QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines: Tibetan "Snow Lotus" herb (Saussurea laniceps), a case study.Tao Yi et al.Journal of ethnopharmacology, 153(3), 701-713 (2014-03-26) Integrated metabolomics and transcriptomics reveal enhanced specialized metabolism in Medicago truncatula root border cells.Bonnie S Watson et al.Plant physiology, 167(4), 1699-1716 (2015-02-11) Using smell to triage samples in point-of-care assays.Hemakesh Mohapatra et al.Angewandte Chemie (International ed. in English), 51(44), 11145-11148 (2012-10-06) Molecular structure, Normal Coordinate Analysis, harmonic vibrational frequencies, Natural Bond Orbital, TD-DFT calculations and biological activity analysis of antioxidant drug 7-hydroxycoumarin.S Sebastian et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 370-381 (2012-11-06) The catalytic process of poly-silicate-ferric (PSF) and generation mechanism of hydroxyl radical based on photo-Fenton system.Zhiqing Liu et al.Water science and technology : a journal of the International Association on Water Pollution Research, 81(4), 709-719 (2020-05-28) UV and Visible Light-Driven Production of Hydroxyl Radicals by Reduced Forms of N, F, and P Codoped Titanium Dioxide.A M Abdullah et al.Molecules (Basel, Switzerland), 24(11) (2019-06-09) Rational design of novel CYP2A6 inhibitors.Niina Tani et al.Bioorganic & medicinal chemistry, 22(23), 6655-6664 (2014-12-03) Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.Jacqueline Ramírez et al.Drug metabolism and disposition: the biological fate of chemicals, 43(7), 928-935 (2015-04-15) 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.Atsushi Kato et al.Bioorganic & medicinal chemistry letters, 20(19), 5630-5633 (2010-09-02) Risto O Juvonen et al.Xenobiotica; the fate of foreign compounds in biological systems, 50(8), 885-893 (2020-01-07)Sulfonation is an important high affinity elimination pathway for phenolic compounds.In this study sulfonation of 7-hydroxycoumarin and 13 its derivatives were evaluated in liver cytosols of human and six animal species. 7-hydroxycoumarin and its derivatives are strongly fluorescent, and their... In vitro isolation, elicitation of psoralen in callus cultures of Psoralea corylifolia and cloning of psoralen synthase gene.Behrooz M Parast et al.Plant physiology and biochemistry : PPB, 49(10), 1138-1146 (2011-04-29) Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1.Stefan Starcević et al.Journal of medicinal chemistry, 54(1), 248-261 (2010-12-09) Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.Ana C A X De-Oliveira et al.PloS one, 10(1), e0117842-e0117842 (2015-01-31) Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.Yoshihiko Shimokawa et al.Biological & pharmaceutical bulletin, 37(11), 1727-1735 (2014-11-05) Polyphenolic Profile of Pear Leaves with Different Resistance to Pear Psylla (Cacopsylla pyri).Milica M Fotirić Akšić et al.Journal of agricultural and food chemistry, 63(34), 7476-7486 (2015-08-19) Effect of digestion and storage of human milk on free fatty acid concentration and cytotoxicity.Alexander H Penn et al.Journal of pediatric gastroenterology and nutrition, 59(3), 365-373 (2014-05-21) Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay.Dany Spaggiari et al.Journal of chromatography. A, 1371, 244-256 (2014-12-03) Fluorescent chemodosimeter for selective detection of cyanide in water.Lee K S, et al. Organic Letters, 10(1), 49-51 (2008) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: kinetic investigations by HPLC.S Huber et al.Journal of pharmaceutical and biomedical analysis, 104, 137-143 (2014-12-17) [Chemical constituents of Pileostegia viburnoides var. glabrescens].Ju-ying Zou et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 724-725 (2012-12-12) Phenotyping of CYP450 in human liver microsomes using the cocktail approach.Dany Spaggiari et al.Analytical and bioanalytical chemistry, 406(20), 4875-4887 (2014-06-05) Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs.In-Hwan Baek et al.Xenobiotica; the fate of foreign compounds in biological systems, 44(11), 975-987 (2014-05-31) Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.Doyoung Kwon et al.Molecular pharmacology, 96(5), 641-654 (2019-09-08) Effects of sorbitol on porcine oocyte maturation and embryo development in vitro.Tao Lin et al.Zygote (Cambridge, England), 23(2), 297-306 (2014-01-05) Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.Siti Nur Fadzilah Muhsain et al.Toxicology and applied pharmacology, 282(1), 77-89 (2014-12-06) Oxygen therapy improves energy metabolism in focal cerebral ischemia.Li Sun et al.Brain research, 1415, 103-108 (2011-08-30) Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.C Preston Pugh et al.Archives of biochemistry and biophysics, 564, 244-253 (2014-12-03) Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.Anna Maria Ferrari et al.European journal of medicinal chemistry, 42(7), 1028-1031 (2007-02-24) Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation.Hiromu Kashida et al.Bioorganic & medicinal chemistry, 20(14), 4310-4315 (2012-06-19) Developmental changes in leaf phenolics composition from three artichoke cvs. (Cynara scolymus) as determined via UHPLC-MS and chemometrics.Amira S El Senousy et al.Phytochemistry, 108, 67-76 (2014-10-11) Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.Soo Hyeon Bae et al.Antimicrobial agents and chemotherapy, 58(9), 5036-5046 (2014-06-04) A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery.Lance Heinle et al.Combinatorial chemistry & high throughput screening, 18(5), 442-452 (2015-04-02) Effects of 8-methoxypsoralen on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.Mingfei Feng et al.Drug metabolism and pharmacokinetics, 30(4), 314-320 (2015-07-27) Effect of colloidal silica on the spectral behaviour of 7-hydroxycoumarin in aqueous medium.Moumita Chakraborty et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 97, 722-727 (2012-08-14) Umbelliferone instability during an analysis involving its extraction process.Andrzej L Dawidowicz et al.Monatshefte fur chemie, 149(8), 1327-1340 (2018-08-14) New halogenated phenylcoumarins as tyrosinase inhibitors.Maria João Matos et al.Bioorganic & medicinal chemistry letters, 21(11), 3342-3345 (2011-04-26) Coumarins content in wine: application of HPLC, fluorescence spectrometry, and chemometric approach.Katarína Hroboňová et al.Journal of food science and technology, 57(1), 200-209 (2020-01-25) Photo responsive monoolein cubic phase containing coumarin-Tween 20 conjugates.Jing Dai et al.Drug development and industrial pharmacy, 39(9), 1457-1463 (2013-08-02) Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets.Ye V Liu et al.Vaccine, 33(18), 2152-2158 (2015-03-17) Solvent and pH Effects of Coumarin-Terminated Monolayer on Silver Particles.Issha Nadirah Ismail et al.Journal of fluorescence, 25(4), 777-785 (2015-06-10) In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand.Victor M Navarro-García et al.Mycoses, 54(5), e569-e571 (2011-05-25) Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.Yuki Kondo et al.PloS one, 9(8), e104010-e104010 (2014-08-02) Functional analysis and transcriptional output of the Göttingen minipig genome.Tobias Heckel et al.BMC genomics, 16, 932-932 (2015-11-18) Short-term effects of the allelochemical umbelliferone on Triticum durum L. metabolism through GC-MS based untargeted metabolomics.Biswapriya B Misra et al.Plant science : an international journal of experimental plant biology, 298, 110548-110548 (2020-08-11) Phagocytosis and killing of Salmonella by 7-hydroxycoumarin activated macrophages.Tsvetanka Stefanova et al.Immunological investigations, 41(2), 199-213 (2011-10-20) Species differences in the metabolism of ritobegron in vitro and assessment of potential interactions with transporters and cytochrome P450 enzymes.Y Abe et al.Die Pharmazie, 70(1), 38-46 (2015-05-16) Identification and functional characterization of novel feline cytochrome P450 2A.Gaku Okamatsu et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(6), 503-510 (2014-12-31) Cell isolation through whole-liver perfusion and preparation of hepatocytes for cytochrome p450 analysis.Sonya O Meheux Methods in molecular biology (Clifton, N.J.), 1001, 43-51 (2013-03-16) Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation.Vasudevan Aparna et al.PloS one, 9(7), e101840-e101840 (2014-07-16) Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.H A M Mutsaers et al.Biochimica et biophysica acta, 1832(1), 142-150 (2012-09-29) Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.Yu Fen Zheng et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 117-127 (2014-03-19) A 2-oxoglutarate-dependent dioxygenase from Ruta graveolens L. exhibits p-coumaroyl CoA 2'-hydroxylase activity (C2'H): a missing step in the synthesis of umbelliferone in plants.Guilhem Vialart et al.The Plant journal : for cell and molecular biology, 70(3), 460-470 (2011-12-16) Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases.Dan Li et al.Neurotoxicology, 33(5), 1368-1374 (2012-09-12) Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives.Prince Firdoos Iqbal et al.European journal of medicinal chemistry, 44(5), 2252-2259 (2008-08-05) Novel Spectrofluorimetric Method for the Determination of Perindopril Erbumine Based on Charge Transfer Reaction with 7-Hydroxycoumarin.Hanan Fael et al.Journal of fluorescence, 25(4), 811-818 (2015-07-08) Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore.Du L, et al. Tetrahedron Letters, 49(19), 3045-3048 (2008) Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San.Xi Huang et al.PloS one, 9(11), e113819-e113819 (2014-11-27) pH induced dual "OFF-ON-OFF" switch: influence of a suitably placed carboxylic acid.Kalyan K Sadhu et al.Organic & biomolecular chemistry, 11(4), 563-568 (2012-10-13) Total synthesis of (+)-angelmarin.Magolan J and Coster M J The Journal of Organic Chemistry, 74(14), 5083-5086 (2009) Synthesis and pharmacological activity of O-aminoalkyl derivatives of 7-hydroxycoumarin.Joanna Trykowska Konc et al.European journal of medicinal chemistry, 46(6), 2252-2263 (2011-03-29) Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation.Vasudevan Aparna et al.PloS one, 9(7), e101840-e101840 (2014-07-16) Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.H A M Mutsaers et al.Biochimica et biophysica acta, 1832(1), 142-150 (2012-09-29) Identification and functional characterization of novel feline cytochrome P450 2A.Gaku Okamatsu et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(6), 503-510 (2014-12-31) Cell isolation through whole-liver perfusion and preparation of hepatocytes for cytochrome p450 analysis.Sonya O Meheux Methods in molecular biology (Clifton, N.J.), 1001, 43-51 (2013-03-16) A 2-oxoglutarate-dependent dioxygenase from Ruta graveolens L. exhibits p-coumaroyl CoA 2'-hydroxylase activity (C2'H): a missing step in the synthesis of umbelliferone in plants.Guilhem Vialart et al.The Plant journal : for cell and molecular biology, 70(3), 460-470 (2011-12-16) Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.Yu Fen Zheng et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 117-127 (2014-03-19) Enantioselective inhibition of carprofen towards UDP-glucuronosyltransferase (UGT) 2B7.Zhong-Ze Fang et al.Chirality, 27(3), 189-193 (2014-12-17) Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases.Dan Li et al.Neurotoxicology, 33(5), 1368-1374 (2012-09-12) Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives.Prince Firdoos Iqbal et al.European journal of medicinal chemistry, 44(5), 2252-2259 (2008-08-05) Molecular cloning and functional analysis of the ortho-hydroxylases of p-coumaroyl coenzyme A/feruloyl coenzyme A involved in formation of umbelliferone and scopoletin in sweet potato, Ipomoea batatas (L.) Lam.Seitaro Matsumoto et al.Phytochemistry, 74, 49-57 (2011-12-16) Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors.Renato F Freitas et al.Bioorganic & medicinal chemistry, 17(6), 2476-2482 (2009-03-04) Umbelliferone and daphnetin ameliorate carbon tetrachloride-induced hepatotoxicity in rats via nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1 expression.Mohamed R Mohamed et al.Environmental toxicology and pharmacology, 38(2), 531-541 (2014-08-30) Modulation of (-)-epicatechin metabolism by coadministration with other polyphenols in Caco-2 cell model.Belén Sanchez-Bridge et al.Drug metabolism and disposition: the biological fate of chemicals, 43(1), 9-16 (2014-10-16) Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells.Stefan Huber et al.PloS one, 10(7), e0133743-e0133743 (2015-07-22) Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.Nadia Touisni et al.Journal of medicinal chemistry, 54(24), 8271-8277 (2011-11-15) Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore.Du L, et al. Tetrahedron Letters, 49(19), 3045-3048 (2008) Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San.Xi Huang et al.PloS one, 9(11), e113819-e113819 (2014-11-27) Investigation of binding properties of umbelliferone (7hydroxycoumarin) to lysozyme.Elmas Gök Journal of fluorescence, 23(2), 333-338 (2012-12-12) Umbelliferone modulates gamma-radiation induced reactive oxygen species generation and subsequent oxidative damage in human blood lymphocytes.Govindasamy Kanimozhi et al.European journal of pharmacology, 672(1-3), 20-29 (2011-09-29) Novel Spectrofluorimetric Method for the Determination of Perindopril Erbumine Based on Charge Transfer Reaction with 7-Hydroxycoumarin.Hanan Fael et al.Journal of fluorescence, 25(4), 811-818 (2015-07-08) [Study on the chemical constituents of Chloranthus multistachys].Xia Liu et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(8), 1254-1256 (2013-01-17) Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines.Céline Bruyère et al.Bioorganic & medicinal chemistry letters, 21(14), 4174-4179 (2011-06-24) A versatile long-wavelength-absorbing scaffold for Eu-based responsive probes.Csongor Szíjjártó et al.Chemistry (Weinheim an der Bergstrasse, Germany), 19(9), 3099-3109 (2013-01-12) Mechanistic Evidence of Viscum schimperi (Viscaceae) Antihyperglycemic Activity: From a Bioactivity-guided Approach to Comprehensive Metabolite Profiling.Hossam M Abdallah et al.Phytotherapy research : PTR, 29(11), 1737-1743 (2015-08-04) Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 43(7), 969-976 (2015-04-11) Structure-inhibition relationship of podophyllotoxin (PT) analogues towards UDP-glucuronosyltransferase (UGT) isoforms.Jia-Qi Qi et al.Die Pharmazie, 70(4), 239-243 (2015-05-28) Anticoagulant activity of some Artemisia dracunculus leaf extracts.Kemal Durić et al.Bosnian journal of basic medical sciences, 15(2), 9-14 (2015-06-05) Synthesis and antiinflammatory activity of coumarin derivatives.Christos A Kontogiorgis et al.Journal of medicinal chemistry, 48(20), 6400-6408 (2005-09-30) Chemical inhibitors of CYP450 enzymes in liver microsomes: combining selectivity and unbound fractions to guide selection of appropriate concentration in phenotyping assays.Ramakrishna Nirogi et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(2), 95-106 (2014-07-30) Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.Shinsuke Marumoto et al.Bioorganic & medicinal chemistry, 20(2), 784-788 (2012-01-10) Integrated sediment quality assessment through biomarker responses and bioavailability measurements: Application in Tai Lake, China.Hong-Xue Qi et al.Ecotoxicology and environmental safety, 119, 148-154 (2015-05-26) 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range.Alfonso Maresca et al.Bioorganic & medicinal chemistry letters, 20(24), 7255-7258 (2010-11-12) 7-Hydroxycoumarin modulates the oxidative metabolism, degranulation and microbial killing of human neutrophils.Luciana M Kabeya et al.Chemico-biological interactions, 206(1), 63-75 (2013-09-03) Structure-inhibition relationship of podophyllotoxin (PT) analogues towards UDP-glucuronosyltransferase (UGT) isoforms.Jia-Qi Qi et al.Die Pharmazie, 70(4), 239-243 (2015-05-28) Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 43(7), 969-976 (2015-04-11) Inhibition of human cytochrome P450 2E1 and 2A6 by aldehydes: structure and activity relationships.Suneel K Kandagatla et al.Chemico-biological interactions, 219, 195-202 (2014-06-14) Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells.Stefan Huber et al.PloS one, 10(7), e0133743-e0133743 (2015-07-22) Umbelliferone and daphnetin ameliorate carbon tetrachloride-induced hepatotoxicity in rats via nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1 expression.Mohamed R Mohamed et al.Environmental toxicology and pharmacology, 38(2), 531-541 (2014-08-30) Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies.Therese Ericsson et al.Xenobiotica; the fate of foreign compounds in biological systems, 44(7), 615-626 (2014-01-10) 7-substituted coumarins inhibit proliferation and migration of laryngeal cancer cells in vitro.Michal Kielbus et al.Anticancer research, 33(10), 4347-4356 (2013-10-15) An efficient synthesis of (+)-decursinol from umbelliferone.Lee J H, et al. Tetrahedron Letters, 48(16), 2889-2892 (2007) CYP2A7 pseudogene transcript affects CYP2A6 expression in human liver by acting as a decoy for miR-126.Masataka Nakano et al.Drug metabolism and disposition: the biological fate of chemicals, 43(5), 703-712 (2015-02-25) Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.Alfonso Maresca et al.Bioorganic & medicinal chemistry letters, 20(15), 4511-4514 (2010-06-29) A novel and unusually long-lived chemiluminophore based on the 7-hydroxycoumarin scaffold.Jan Kočí et al.Chemical communications (Cambridge, England), 47(23), 6713-6715 (2011-05-17) Chiral Inhibition of Rivaroxaban Derivatives Towards UDP-Glucuronosyltransferase (UGT) Isoforms.Zhuhua Yao et al.Chirality, 27(12), 936-943 (2015-10-02) Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 43(10), 1408-1416 (2015-08-01) Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia.Andrew Baxter et al.Toxicology in vitro : an international journal published in association with BIBRA, 29(5), 864-875 (2015-04-12) Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.Adriana Chilin et al.Journal of medicinal chemistry, 51(4), 752-759 (2008-02-07) Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.Theodoros Symeonidis et al.Bioorganic & medicinal chemistry letters, 19(4), 1139-1142 (2009-01-20) Solvent effect on the fluorescence response of hydroxycoumarin bearing a dipicolylamine binding site to metal ions.Hiroyuki Kobayashi et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 30(11), 1045-1050 (2014-11-11) Inhibitory effects of Hwang-Ryun-Hae-Dok-Tang on cytochrome P450 in human liver microsomes.Sang Yoon Lee et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(2), 131-138 (2014-08-26) Photoprotolytic Processes of Umbelliferone and Proposed Function in Resistance to Fungal Infection.Ron Simkovitch et al.The journal of physical chemistry. B, 119(46), 14683-14696 (2015-10-22) Sulfakinin is an important regulator of digestive processes in the migratory locust, Locusta migratoria.Sven Zels et al.Insect biochemistry and molecular biology, 61, 8-16 (2015-04-08) Oxidative modification of rat sulfotransferase 1A1 activity in hepatic tissue slices correlates with effects on the purified enzyme.Jagadeesha K Dammanahalli et al.Drug metabolism and disposition: the biological fate of chemicals, 40(2), 298-303 (2011-11-02) Synthesis and anti-inflammatory activity of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives.Francesco Epifano et al.Bioorganic & medicinal chemistry letters, 17(20), 5709-5714 (2007-09-05) Coumarins as new matrices for matrix-assisted laser-desorption/ionization Fourier transform ion cyclotron resonance mass spectrometric analysis of hydrophobic compounds.Hang Wang et al.Analytica chimica acta, 882, 49-57 (2015-06-05)

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