Melting point	36-39 ºC
Water Solubility	Insoluble
Boiling point	260 ºC
Flash point	138 ºC

Symbol(GHS)	Xn
Hazard Codes	R22;R36/38
SDS/MSDS	S26;S37/39

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins.Federica Menichini et al.Pharmaceutical biology, 48(9), 1059-1065 (2010-08-10) [Phamacokinetic study of bergapten in rats plasma by LC-MS/MS].Yufeng Ma et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(3), 381-383 (2012-05-10) Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination.M L Panno et al.Breast cancer research and treatment, 136(2), 443-455 (2012-10-12) Caffeine as a photoprotective agent for diminishing phototoxicity.Yim Tong Szeto et al.Toxicology and industrial health, 26(10), 667-670 (2010-07-16) Pharmacokinetic studies of bergapten in dog plasma by using a LC-MS/MS method studies.Y Gao et al.Drug research, 63(7), 338-341 (2013-04-04) Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.Yan Liu et al.Science translational medicine, 6(266), 266ra170-266ra170 (2014-12-17) Flu-like syndrome, bronchoconstriction and fever caused by 5-methoxypsoralen: the first case report and literature review.Lucia Mantovani et al.Dermatology (Basel, Switzerland), 223(3), 213-215 (2011-05-18) Breast cancer cell survival signal is affected by bergapten combined with an ultraviolet irradiation.Maria Luisa Panno et al.FEBS letters, 584(11), 2321-2326 (2010-04-08) Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.Shinsuke Marumoto et al.Bioorganic & medicinal chemistry, 20(2), 784-788 (2012-01-10) Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica.Domenico Bonamonte et al.Contact dermatitis, 62(6), 343-348 (2010-06-19) Simultaneous and sensitive determination of xanthotoxin, psoralen, isoimpinellin and bergapten in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.Wei Yang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(5-6), 575-582 (2010-02-02) Biotransformation of bergapten and xanthotoxin by Glomerella cingulata.Shinsuke Marumoto et al.Journal of agricultural and food chemistry, 58(13), 7777-7781 (2010-06-10) Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study.Jarogniew J Łuszczki et al.Pharmacological reports : PR, 62(6), 1231-1236 (2011-01-29) [Chemical constituents contained in seeds of Notopterygium franchetii].Yanxia Zhang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(7), 941-945 (2012-07-17) Immunotoxicity activity of natural furocoumarins from milky sap of Ficus carica L. against Aedes aegypti L.Iii-Min Chung et al.Immunopharmacology and immunotoxicology, 33(3), 515-518 (2011-01-11) Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.Vinicius Barreto da Silva et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 12(3), 378-387 (2010-01-14) 5-Methoxypsoralen plus ultraviolet (UV) A is superior to medium-dose UVA1 in the treatment of severe atopic dermatitis: a randomized crossover trial.S Tzaneva et al.The British journal of dermatology, 162(3), 655-660 (2009-09-23) Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures.Nicole Raquet et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 257-266 (2014-04-01) Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.Wei-Xia Liu et al.World journal of gastroenterology, 18(18), 2197-2202 (2012-05-23) Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures.Renuka Diwan et al.Natural product communications, 7(7), 895-898 (2012-08-23) Rapid characterization of cross-links, mono-adducts, and non-covalent binding of psoralens to deoxyoligonucleotides by LC-UV/ESI-MS and IRMPD mass spectrometry.Suncerae I Smith et al.The Analyst, 135(5), 943-952 (2010-04-27) Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registry.M Inzinger et al.The British journal of dermatology, 165(3), 640-645 (2011-05-14) Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys.Sailesh Konda et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(5), 1092-1095 (2011-02-02) [High-performance liquid chromatography for determination of psoralene, bergapten and apigenin in Ficus hirta Vahl].Yan-jun Yang et al.Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 30(11), 2565-2567 (2010-11-26) Antagonistic regulation, yet synergistic defense: effect of bergapten and protease inhibitor on development of cowpea bruchid Callosobruchus maculatus.Fengguang Guo et al.PloS one, 7(8), e41877-e41877 (2012-08-29) Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.Alessia Salvador et al.ChemMedChem, 5(9), 1506-1512 (2010-07-21) Bergapten induces G1 arrest of non‑small cell lung cancer cells, associated with the p53‑mediated cascade.Shyh-Ren Chiang et al.Molecular medicine reports, 19(3), 1972-1978 (2019-01-11) The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsoralen.Tatsushi Goto et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2110-2116 (2010-08-28) 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo.W McNeely et al.Drugs, 56(4), 667-690 (1998-11-07)

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