Melting point	181-186 ºC
Boiling point	275 ºC
Flash point	185 ºC
Density	1.385
Refractive index	1.571-1.576

SDS/MSDS	S24/25

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Amiodarone	1951-25-3	View

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Articles

Peer-Reviewed Papers

Thermodynamic investigations of nitroxoline sublimation by simultaneous DSC-FTIR method and isothermal TG analysis.Gau-Yi Gao et al.Journal of pharmaceutical sciences, 99(1), 255-261 (2009-06-17) Effect of nitroxoline on angiogenesis and growth of human bladder cancer.Joong Sup Shim et al.Journal of the National Cancer Institute, 102(24), 1855-1873 (2010-11-20) The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc.A Sobke et al.Antimicrobial agents and chemotherapy, 56(11), 6021-6025 (2012-08-29) [Microbiological consequences of chelation of bivalent metal cations by nitroxoline].C Pelletier et al.Pathologie-biologie, 42(5), 406-411 (1994-05-01) Substituted oxines inhibit endothelial cell proliferation and angiogenesis.Shridhar Bhat et al.Organic & biomolecular chemistry, 10(15), 2979-2992 (2012-03-07) Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives.Izidor Sosič et al.Journal of medicinal chemistry, 56(2), 521-533 (2012-12-21) Effects of subinhibitory concentrations of nitroxoline on the surface properties of Escherichia coli.H Latrache et al.Folia microbiologica, 45(6), 485-490 (2001-08-15) [Present status of nitroxoline].E Bergogne-Berezin et al.Pathologie-biologie, 35(5 Pt 2), 873-878 (1987-06-01) Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline).Hongchao Jiang et al.Cancer letters, 312(1), 11-17 (2011-09-09) [Intensive combined therapy of patients with urogenital tuberculosis].B V Soloveĭ et al.Problemy tuberkuleza, (1)(1), 30-32 (1995-01-01) [Relation of the chelating property of nitroxoline, the surface hydrophobicity and the inhibition of bacterial adherence].P Bourlioux et al.Pathologie-biologie, 37(5 Pt 2), 600-604 (1989-06-01) Roles of divalent cations and pH in mechanism of action of nitroxoline against Escherichia coli strains.C Pelletier et al.Antimicrobial agents and chemotherapy, 39(3), 707-713 (1995-03-01) Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride.A V Yatsenko et al.Acta crystallographica. Section C, Crystal structure communications, 58(Pt 1), o19-o21 (2002-01-10) [The characteristics of extracting 2-acetylamino-5-nitrothiazole and 5-nitro-8-hydroxyquinoline from aqueous solutions].V K Shormanov et al.Sudebno-meditsinskaia ekspertiza, 37(3), 26-28 (1994-07-01) Electrochemistry of the antibacterial and antifungal drug nitroxoline and its determination in bulk form, pharmaceutical formulation and human blood.Mohamed M Ghoneim et al.Bioelectrochemistry (Amsterdam, Netherlands), 80(2), 162-168 (2010-09-14) Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells.Serena Veschi et al.Journal of experimental & clinical cancer research : CR, 37(1), 236-236 (2018-09-23) [Urinary tract infections in Dakar: etiologies, therapeutic basis].A I Sow et al.Dakar medical, 45(1), 59-61 (2003-12-12) [Inhibition of bacterial adherence by nitroxoline on cellular adhesion and on urinary catheter surfaces].P Bourlioux et al.Pathologie-biologie, 37(5), 451-454 (1989-05-01) [Direct effect of nitroxoline in the inhibition of bacterial adherence to urinary catheters].L Oliviero et al.Pathologie-biologie, 38(5), 455-458 (1990-05-01) Activity in vitro of urine samples from patients treated by nitroxoline against mycoplasmas.A Amgar et al.Journal of chemotherapy (Florence, Italy), 1(4 Suppl), 226-228 (1989-07-01) In vitro activity of the chelating agents nitroxoline and oxine against Mycobacterium bovis BCG.B Murugasu-Oei et al.International journal of antimicrobial agents, 18(6), 579-582 (2001-12-12) Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents.Serena Veschi et al.Journal of enzyme inhibition and medicinal chemistry, 35(1), 1331-1344 (2020-06-27) Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.Bojana Mirković et al.PloS one, 6(11), e27197-e27197 (2011-11-11) [Disorders of kidney function in patients with benign prostatic hyperplasia].V E Rodoman et al.Urologiia i nefrologiia, (6)(6), 24-26 (1998-02-14) In vitro activity of nitroxoline against clinical isolates of Candida species.J M Hernández Molina et al.Mycoses, 34(7-8), 323-325 (1991-07-01) [Antifungal activity of nitroxoline].J M Hernández et al.Enfermedades infecciosas y microbiologia clinica, 9(7), 439-440 (1991-08-01) Experimental and theoretical quantum chemical investigations of 8-hydroxy-5-nitroquinoline.V Arjunan et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 506-516 (2012-06-26) Nitroxoline: a potent antimicrobial agent against multidrug resistant Enterobacteriaceae.Rungrot Cherdtrakulkiat et al.EXCLI journal, 18, 445-453 (2019-08-20) [Is nitroxoline an allergen?].F Rodor et al.Therapie, 57(2), 204-205 (2002-08-21) Highly CO2-soluble 5-Amido-8-hydroxyquinoline Chelating Agents for Extraction of Metals in Sc-CO2.Chang F, et al. Bull. Korean Chem. Soc., 29(7), 1327-1327 (2008)

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