Melting point	146-151 ºC
Water Solubility	slightly soluble

Symbol(GHS)	Xn;N
Hazard Codes	R22;R36/37/38;R51/53;R62
SDS/MSDS	S26;S36/37/39;S61

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Confirmation of carbadox and olaquindox metabolites in porcine liver using liquid chromatography-electrospray, tandem mass spectrometry.M J Hutchinson et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 816(1-2), 15-20 (2005-01-25) Quinoxaline-2-carboxylic acid in pigs: criteria to distinguish between the illegal use of carbadox and environmental contamination.M J Hutchinson et al.Food additives and contaminants, 21(6), 538-544 (2004-06-19) An immunoaffinity column for the selective purification of 3-methyl-quinoxaline-2-carboxylic acid from swine tissues and its determination by high-performance liquid chromatography with ultraviolet detection and a colloidal gold-based immunochromatographic assay.Dapeng Peng et al.Food chemistry, 237, 290-296 (2017-08-03) Validation of a streamlined multiclass, multiresidue method for determination of veterinary drug residues in bovine muscle by liquid chromatography-tandem mass spectrometry.Marilyn J Schneider et al.Analytical and bioanalytical chemistry, 407(15), 4423-4435 (2014-12-30) Quinoxaline studies. 13. N-(2-Quinoxaloyl)-alpha-amino acids.S Gerchakov et al.Journal of medicinal chemistry, 9(2), 266-268 (1966-03-01) Sorption of naphthoic acids and quinoline compounds to estuarine sediment.William D Burgos et al.Journal of contaminant hydrology, 84(3-4), 107-126 (2006-02-14) Novel surface molecularly imprinted sol-gel polymer applied to the online solid phase extraction of methyl-3-quinoxaline-2-carboxylic acid and quinoxaline-2-carboxylic acid from pork muscle.Zhen-Juan Duan et al.Analytical and bioanalytical chemistry, 401(7), 2291-2299 (2011-08-23) Development and validation of an improved method for confirmation of the carbadox metabolite, quinoxaline-2-carboxylic acid, in porcine liver using LC-electrospray MS-MS according to revised EU criteria for veterinary drug residue analysis.M J Hutchinson et al.The Analyst, 127(3), 342-346 (2002-05-09) Quinoxaline-2-carboxylic acid (QCA) in swine liver and muscle.M Rutalj et al.Food additives and contaminants, 13(8), 879-882 (1996-11-01) Synthetic Approaches to Quinoxaline Antibiotics. Synthesis of Bisquinoxaloyl Derivatives1a.Koppel HC, et al. The Journal of Organic Chemistry, 28(4), 1119-1122 (1963) Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals.D Peng et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(11), 1524-1533 (2011-08-11) Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken.Lingli Huang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 874(1-2), 7-14 (2008-10-08) Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture.Alex P Praseuth et al.Biotechnology progress, 24(1), 134-139 (2008-01-05) Identification and stereochemical assignment of the beta-hydroxytryptophan intermediate in the echinomycin biosynthetic pathway.Kento Koketsu et al.Organic letters, 8(21), 4719-4722 (2006-10-06) Biofunctionalized zinc oxide field effect transistors for selective sensing of riboflavin with current modulation.Joshua A Hagen et al.Sensors (Basel, Switzerland), 11(7), 6645-6655 (2011-12-14) Synthesis and AMPA receptor antagonistic activity of a novel class of quinoxalinecarboxylic acid with a substituted phenyl group at the C-7 position.Yasuo Takano et al.Bioorganic & medicinal chemistry letters, 13(20), 3521-3525 (2003-09-25) In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan.Chen Zhang et al.PloS one, 8(2), e56772-e56772 (2013-02-26) Residues of carbadox metabolites in edible pork products.A J Baars et al.Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 14, 288-292 (1991-01-01) [Determination of the residues of 3-methyl-quinoxaline-2-carboxylic acid and quinoxaline-2-carboxylic acid in animal origin foods by high performance liquid chromatography-tandem mass spectrometry].Ling Zheng et al.Se pu = Chinese journal of chromatography, 30(7), 660-664 (2012-11-30) [Determination of carbadox metabolites, quinoxaline-2-carboxylic acid and desoxycarbadox, in swine muscle and liver by liquid chromatography/mass spectrometry].Masakazu Horie et al.Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 45(3), 135-140 (2004-10-08) Electrochemical sensor based on molecularly imprinted polymer film via sol-gel technology and multi-walled carbon nanotubes-chitosan functional layer for sensitive determination of quinoxaline-2-carboxylic acid.Yukun Yang et al.Biosensors & bioelectronics, 47, 475-481 (2013-04-30) Quinoxalin-2-carboxamides: synthesis and pharmacological evaluation as serotonin type-3 (5-HT3) receptor antagonists.Radhakrishnan Mahesh et al.Journal of enzyme inhibition and medicinal chemistry, 26(5), 610-615 (2011-01-13) Studies on antibiotic biosynthesis by protoplasts and resting cells of Streptomyces echinatus. Part II. Effect of chromophore precursors.D Gauvreau et al.Canadian journal of microbiology, 32(5), 363-372 (1986-05-01) Development of a high-performance liquid chromatography method for the simultaneous quantification of quinoxaline-2-carboxylic acid and methyl-3-quinoxaline-2-carboxylic acid in animal tissues.Yujie Wu et al.Journal of chromatography. A, 1146(1), 1-7 (2007-03-06) Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics.Yuki Hirose et al.The Journal of antibiotics, 64(1), 117-122 (2010-11-26) Development and validation of an immunochromatographic assay for the rapid detection of quinoxaline-2-carboxylic acid, the major metabolite of carbadox in the edible tissues of pigs.T Le et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(6), 925-934 (2012-03-20) Determination of quinoxaline carboxylic acid (metabolite of carbadox) in animal tissue by HPLC.M D Rose et al.Food additives and contaminants, 12(2), 177-183 (1995-03-01) Quantum mechanical study of the structure and spectroscopic (FT-IR, FT-Raman, 13C, 1H and UV), NBO and HOMO-LUMO analysis of 2-quinoxaline carboxylic acid.N Prabavathi et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 92, 325-335 (2012-03-27) Directed biosynthesis of novel derivatives of echinomycin by Streptomyces echinatus. I. Effect of exogenous analogues of quinoxaline-2-carboxylic acid on the fermentation.D Gauvreau et al.Canadian journal of microbiology, 30(4), 439-450 (1984-04-01)

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