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4-Acetamidophenol | CAS:103-90-2
4-Acetamidophenol
  • Name:4-Acetamidophenol
  • CAS:103-90-2
  • Synonyms:p-Hydroxyacetanilide; Acetaminophen; Paracetamol; N-Acetyl-4-aminophenol; APAP
  • Molecular Formula:C8H9NO2
  • Molecular Weight:151.16
  • EINESC:203-157-5

Description

Properties

Melting point 168-172 ºC
Water Solubility 14 g/L (20 ºC)

Safety

Symbol(GHS) Xn
Hazard Codes R22;R36/38;R52/53
SDS/MSDS S26;S37/39;S61

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Conformational preferences and cis-trans isomerization of L-3,4-dehydroproline residue.Young Kee Kang et al.Biopolymers, 92(5), 387-398 (2009-04-18) Oxidation of 3,4-dehydro-D-proline and other D-amino acid analogues by D-alanine dehydrogenase from Escherichia coli.Charles E Deutch FEMS microbiology letters, 238(2), 383-389 (2004-09-11) Complement subcomponent C1q modulation of TNF-alpha binding to L929 cells for enhanced TNF-mediated cytotoxicity.H Jiang et al.Scandinavian journal of immunology, 44(2), 101-107 (1996-08-01) Inhibition of a prolyl hydroxylase domain (PHD) by substrate analog peptides.Hyuk Sung Kwon et al.Bioorganic & medicinal chemistry letters, 21(14), 4325-4328 (2011-06-15) Purification, characterization, and crystallization of human pyrroline-5-carboxylate reductase.Zhaohui Meng et al.Protein expression and purification, 49(1), 83-87 (2006-04-08) Two genes encoding extension-like proteins are predominantly expressed in tomato root hair cells.M Bucher et al.Plant molecular biology, 35(4), 497-508 (1998-02-12) Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence.G Xiao et al.Molecular endocrinology (Baltimore, Md.), 11(8), 1103-1113 (1997-07-01) Acute respiratory failure (1985) Regulation of collagenase-3 and osteocalcin gene expression by collagen and osteopontin in differentiating MC3T3-E1 cells.Richard C D'Alonzo et al.The Journal of biological chemistry, 277(27), 24788-24798 (2002-04-20) Alternative methods to limit extracellular bacterial activity for enumeration of intracellular bacteria.Hyun-Ju Kim et al.Journal of microbiological methods, 64(1), 17-26 (2005-06-02) Roles of extensins in cotyledon primordium formation and shoot apical meristem activity in Nicotiana tabacum.XueLian Zhang et al.Journal of experimental botany, 59(14), 4045-4058 (2008-10-22) PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis.L K McCauley et al.Journal of cellular biochemistry, 61(4), 638-647 (1996-06-15) Inhibitor of C1q secretion suppresses the macrophage response to lipid A for nitric oxide but not for TNF production: evidence for a role of C1q in autocrine binding of TNF.R W Leu et al.Immunobiology, 188(3), 242-258 (1993-07-01) Synthesis of (2R,3R,4S)-2-hydroxymethylpyrrolidine-3,4-diol from (2S)-3,4-dehydroproline derivatives.D M Goli et al.Carbohydrate research, 259(2), 219-241 (1994-06-17) Root border-like cells of Arabidopsis. Microscopical characterization and role in the interaction with rhizobacteria.Maïté Vicré et al.Plant physiology, 138(2), 998-1008 (2005-05-24) Cell proliferation of human fibroblasts and osteoblasts in osteogenesis imperfecta: influence of age.N S Fedarko et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 10(11), 1705-1712 (1995-11-01) Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.Dongxia Li et al.The Journal of biological chemistry, 279(53), 55051-55059 (2004-10-16) 3,4-Dehydroproline inhibits cell wall assembly and cell division in tobacco protoplasts.J B Cooper et al.Plant physiology, 104(2), 747-752 (1994-02-01) Enhanced and feedback-resistant gamma-glutamyl kinase activity of an Escherichia coli transformant carrying a mutated proB gene of Streptococcus thermophilus.I Massarelli et al.FEMS microbiology letters, 182(1), 143-147 (1999-12-29) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.Griet Van Zeebroeck et al.Nature chemical biology, 5(1), 45-52 (2008-12-09) Evidence for a role of collagen synthesis in arterial smooth muscle cell migration.E F Rocnik et al.The Journal of clinical investigation, 101(9), 1889-1898 (1998-06-13) Factors that affect oxygen activation and coupling of the two redox cycles in the aromatization reaction catalyzed by NikD, an unusual amino acid oxidase.Phaneeswara-Rao Kommoju et al.Biochemistry, 48(40), 9542-9555 (2009-08-26) Extracellular matrix regulates induction of alkaline phosphatase expression by ascorbic acid in human fibroblasts.T Abe et al.Journal of cellular physiology, 189(2), 144-151 (2001-10-13) Recognition and ordering at surfaces: the importance of handedness and footedness.Andrew G Mark et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 12(8), 1474-1480 (2011-04-28) Molecular characterization of NikD, a new flavoenzyme important in the biosynthesis of nikkomycin antibiotics.David Venci et al.Biochemistry, 41(52), 15795-15802 (2002-12-27) Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate.Chad N Hancock et al.Amino acids, 48(3), 859-872 (2015-12-15) In vitro reconstitution of the first steps of anatoxin-a biosynthesis in Oscillatoria PCC 6506: from free L-proline to acyl carrier protein bound dehydroproline.Annick Méjean et al.Biochemistry, 49(1), 103-113 (2009-12-04) Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro.Hannu Järveläinen et al.Arteriosclerosis, thrombosis, and vascular biology, 24(1), 67-72 (2003-11-15) Synthesis of 4-aryl-2-pyrrolidones and beta-aryl-gamma-amino-butyric acid (GABA) analogues by Heck arylation of 3-pyrrolines with arenediazonium tetrafluoroborates. Synthesis of (+/-)-rolipram on a multigram scale and chromatographic resolution by semipreparative chiral simulated moving bed chromatography.Ariel L L Garcia et al.The Journal of organic chemistry, 70(3), 1050-1053 (2005-01-29) Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion.T A Sullivan et al.The Journal of biological chemistry, 269(36), 22500-22506 (1994-09-09) The influence of proline analogs on bleomycin-induced lung injury in rats.A Ledwozyw Acta physiologica Hungarica, 83(2), 195-202 (1995-01-01) Collagen/annexin V interactions regulate chondrocyte mineralization.Hyon Jong Kim et al.The Journal of biological chemistry, 283(16), 10310-10317 (2008-02-19) Developmental localization and the role of hydroxyproline rich glycoproteins during somatic embryogenesis of banana (Musa spp. AAA).Chunxiang Xu et al.BMC plant biology, 11, 38-38 (2011-02-26)
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