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3-Diethylaminopropylamine | CAS:104-78-9
3-Diethylaminopropylamine
  • Name:3-Diethylaminopropylamine
  • CAS:104-78-9
  • Synonyms:3-Aminopropyldiethylamine; N,N-Diethyl-1,3-propanediamine; N,N-Diethyl-1,3-diaminopropane
  • Molecular Formula:C7H18N2
  • Molecular Weight:130.23
  • EINESC:203-236-4

Description

Properties

Melting point -60 ºC
Water Solubility MISCIBLE
Boiling point 168-171 ºC
Flash point 53 ºC
Density 0.82
Refractive index 1.4406-1.4426

Safety

Symbol(GHS) C
Hazard Codes R10;R21/22;R34;R43
SDS/MSDS S26;S36/37/39;S45

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
In vivo study of liposomes as drug carriers to oral mucosa using EPR oximetry.V Erjavec et al.International journal of pharmaceutics, 307(1), 1-8 (2005-11-01) Efficient transesterification/acylation reactions mediated by N-heterocyclic carbene catalysts.Grasa GA, et al. The Journal of Organic Chemistry, 68(7), 2812-2819 (2003) Supplementation of flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition.K Neukam et al.Skin pharmacology and physiology, 24(2), 67-74 (2010-11-20) In situ permeation study of drug through the stratum corneum using attenuated total reflectance [corrected] Fourier transform infrared spectroscopic imaging.Jean-Michel Andanson et al.Journal of biomedical optics, 14(3), 034011-034011 (2009-07-02) Comparison of blood flow to the cutaneous temperature and redness after topical application of benzyl nicotinate.Ute Jacobi et al.Journal of biomedical optics, 11(1), 014025-014025 (2006-03-11) Lip plumper contact urticaria.Elnaz F Firoz et al.Journal of the American Academy of Dermatology, 60(5), 861-863 (2009-04-25) Modulation of tumor hypoxia by topical formulations with vasodilators for enhancing therapy.Zrinka Abramovic et al.Advances in experimental medicine and biology, 701, 75-82 (2011-03-30) Synthesis of benzylpalladium complexes through C-O bond cleavage of benzylic carboxylates: Development of a novel palladium-catalyzed benzylation of olefins.Narahashi H, et al. Journal of Organometallic Chemistry, 693(2), 283-296 (2008) Skin oxygenation after topical application of liposome-entrapped benzyl nicotinate as measured by EPR oximetry in vivo: influence of composition and size.Julijana Kristl et al.AAPS pharmSci, 5(1), E2-E2 (2003-04-26) Estimation of serum protein binding of compounds metabolized in serum using matrix inhibition.Takahide Uchimura et al.Biopharmaceutics & drug disposition, 29(5), 308-310 (2008-05-23) [On interactions of drugs on and in the skin/comparative studies on the mutual influences of ethyleneglycol-monosalicylate and benzylnicotinate (author's transl)].A Zesch et al.Dermatosen in Beruf und Umwelt. Occupation and environment, 29(6), 161-167 (1981-01-01) In vivo study of different ointments for drug delivery into oral mucosa by EPR oximetry.Milan Petelin et al.International journal of pharmaceutics, 270(1-2), 83-91 (2004-01-17) Rhodium-catalyzed enantioselective addition of boronic acids to N-benzylnicotinate salts.Nadeau Christian et al.Journal of the American Chemical Society, 133(9), 2878-2880 (2011-02-12) Kinetics of blood flow after topical application of benzyl nicotinate on different anatomic sites.Ute Jacobi et al.Archives of dermatological research, 298(6), 291-300 (2006-09-13) Measurement of drug and macromolecule diffusion across atherosclerotic rabbit aorta ex vivo by attenuated total reflection-Fourier transform infrared imaging.Francesca Palombo et al.Journal of biomedical optics, 14(4), 044008-044008 (2009-09-04) Effects of water activity and low molecular weight humectants on skin permeability and hydration dynamics - a double-blind, randomized and controlled study.C Albèr et al.International journal of cosmetic science, 36(5), 412-418 (2014-05-03) Effect of benzyl nicotinate on the percutaneous absorption of dexamethasone in the rat.M A Kassem et al.European journal of drug metabolism and pharmacokinetics, 5(1), 25-28 (1980-01-01) Influence of nanosized delivery systems with benzyl nicotinate and penetration enhancers on skin oxygenation.Zrinka Abramović et al.International journal of pharmaceutics, 359(1-2), 220-227 (2008-05-13) Enhancement of bioavailability by lowering of fat content in topical formulations.K Wirén et al.The British journal of dermatology, 160(3), 552-556 (2009-01-06) Improved skin oxygenation after benzyl nicotinate application in different carriers as measured by EPR oximetry in vivo.M Krzic et al.Journal of controlled release : official journal of the Controlled Release Society, 70(1-2), 203-211 (2001-02-13) Blood flow enhancement in skin or oral mucosa after the topical application of liposome entrapped rubifacient as measured by EPR oximetry in vivo: the influence of size and liposome composition.Marjeta Sentjurc Cellular & molecular biology letters, 7(2), 256-258 (2002-07-05)
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